المؤلفون: Hilton, L. K, Collinge, B, Rushton, C. K, Ben‐Neriah, S, Dreval, K, Grande, B. M, Boyle, M, Meissner, B, Slack, G. W, Farinha, P, Craig, J. W, Gerrie, A. S., Freeman, C, Villa, D, Savage, K. J, Sehn, L. H, Marra, M. A, Steidl, C, Morin, R. D, Scott, D. W

المصدر: Hematological Oncology ; volume 39, issue S2 ; ISSN 0278-0232 1099-1069

الإتاحة: https://doi.org/10.1002/hon.24_2879Test

المؤلفون: Brunetti, G, Cardaioli, F, De Lazzari, M, Cipriani, A, Cecere, AG, Cecchetto, A, Baritussio, A, Giorgi, B, Motta, R, De Conti, G, Tarantini, G, Cacciavillani, L, Iliceto, S, Perazzolo Marra, M

المصدر: European Heart Journal - Cardiovascular Imaging ; volume 22, issue Supplement_2 ; ISSN 2047-2404 2047-2412

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine, Radiology, Nuclear Medicine and imaging, General Medicine

الوصف: Funding Acknowledgements Type of funding sources: None. Background Left ventricular thrombosis (LVT) is a possible complication following myocardial infarction (MI). Besides infarct size, risk factors for LVT include ST-elevated MI (STEMI), anterior and apical location, reduced left ventricular ejection fraction (LVEF) and the presence of microvascular obstruction. Echocardiography quantified myocardial strain has been associated with LVT following MI. Recently, global longitudinal strain, calculated with feature tracking (FT) - CMR, emerged as an independent predictor of major cardiovascular events following MI. Anyway, the relationship between abnormalities on FT-CMR and LVT following MI is still unexplored. Aim of our study is to investigate the possible association between abnormal strain on FT-CMR and LVT following apical STEMI. Methods We performed a retrospective analysis including all patients with a previous apical STEMI, who underwent CMR at our Institute between August 2013 and October 2020. Patients with ongoing anticoagulant therapy were excluded. Differences in global and segmental strain on CMR between patients with and without LVT were tested in a propensity-matched sample, using LVEF, age, gender, time from MI diagnosis and number of LV segments with transmural late gadolinium enhancement (LGE) as covariates to assign propensity score. Furthermore, difference in terms of apical to global radial strain percentual deviation (AGD), calculated as [(Global Radial Strain – Apical Radial Strain)/Global Radial Strain] * 100, was tested. Results Of 356 patients with apical STEMI undergoing CMR at our center, 37 (10.4%) were diagnosed with LVT. After performing a propensity score matching, we obtained a sample of 36 pairs, with a mean age of 65 (SD 11) years, and a median EF of 35% (IQR 27-42); 59 (82%) of them were male. A significant difference in terms of apical radial strain was found between the two groups, with a median strain of 10.75 (IQR 6.8–16.5) in patients without LVT compared to a ...

الإتاحة: https://doi.org/10.1093/ehjci/jeab090.077Test
http://academic.oup.com/ehjcimaging/article-pdf/22/Supplement_2/jeab090.077/38938217/jeab090.077.pdfTest

المؤلفون: Cecere, A, De Lazzari, M, Cipriani, A, Giorgi, B, Motta, R, Iliceto, S, Perazzolo Marra, M

المصدر: European Heart Journal - Cardiovascular Imaging ; volume 22, issue Supplement_2 ; ISSN 2047-2404 2047-2412

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine, Radiology, Nuclear Medicine and imaging, General Medicine

الوصف: Funding Acknowledgements Type of funding sources: None. Background. Arrhythmic mitral valve prolapse (MVP) is characterized by left ventricular (LV) fibrosis in the basal inferolateral wall and papillary muscles. We hypothesized that LV fibrosis are driven by excessive mechanical forces acting on myocardial susceptible cells, representing the last step in the MVP-induced myocardial stretch process. Purpose. We aimed to evaluate the LV myocardial deformation, using strain assessed with cardiac magnetic resonance (CMR), in arrhythmic MVP patients with normal LV ejection fraction (LVEF) and absent/trivial mitral regurgitation (MR) and its correlation with the presence of LV fibrosis, detected by late gadolinium enhancement (LGE) in post-contrast CMR images. Methods. We enrolled consecutive arrhythmic MVP patients with normal LVEF and no/trivial MR. Sixty-nine (39 female; median age: 40 years) patients without MVP, arrhythmias or cardiovascular history served as control group. All patients underwent CMR for identification of LGE and evaluation of LV myocardial deformation. Results. A total of 66 patients were enrolled (47 female; median age: 44 years). In the overall MVP population, LGE was present in 41 patients (62.1%). MVP patients without LGE (25 patients, 37.9%) presented a higher global radial (median: 42.19 vs 33; p: <0.0001) and higher global longitudinal strain (median: -21.61 vs -18.10; p: <0.0001), compared to the control group. A reduction of regional basal posterolateral radial (BPL median: 50.60 vs 67.30; p: 0.0015) and longitudinal strain (BPL median: -23.50 vs -26.70; p: 0.0186) were observed in the MVP patients as compared with controls (Figures A-D). Conversely to the basal region, mid anterolateral and posterolateral region presented a higher radial (MAL median: 52.60 vs 31.10; p: < 0.0001 and MPL median: 52.80 vs 21.50; p: < 0.0001) and longitudinal strain (MAL median: -24.80 vs -18.30; p: < 0.0001 and MPL median: -25.30 vs -14.80; p: < 0.0001), ...

الإتاحة: https://doi.org/10.1093/ehjci/jeab090.047Test
http://academic.oup.com/ehjcimaging/article-pdf/22/Supplement_2/jeab090.047/38937903/jeab090.047.pdfTest

المؤلفون: Marra, M, Lucci, C, Huertas-Leyva, P, Baldanzini, N, Pierini, M, Savino, G

المصدر: IOP Conference Series: Materials Science and Engineering ; volume 1038, issue 1, page 012016 ; ISSN 1757-8981 1757-899X

الوصف: Motorcycle Autonomous Emergency Braking system (MAEB), is a technology that introduces also on Powered-Two-Wheelers (PTWs) the autonomous braking, which is able to apply autonomously a braking force to reduce impact speed in emergency situations. This system was shown to be possibly effective in reducing numbers of deaths and serious injuries resulting from motorcycle crashes. However, its safe applicability on standard vehicles and the acceptability among end-users has still to be proven. The goal of the study presented in this paper is to assess the acceptability and the controllability of automatic braking events deployed in realistic riding manoeuvres. Field tests were conducted involving 55 common riders as participants on three test vehicles: a naked motorcycle, a sport touring motorcycle and three-wheels scooter. The automatic braking was tested in four riding manoeuvres (straight-lane, lane-change, slalom, and curve) deployed remotely by an investigator at a travelling speed of 35-50 km/h. The system was tested with the higher levels of interventions tested so far by common users and more than 1100 interventions were recorded. The results of this study will allow having a new understanding on the limits of MAEB system.

الإتاحة: https://doi.org/10.1088/1757-899x/1038/1/012016Test

المؤلفون: Mammana, M., Dell'Amore, A., Ferrigno, P., Faccioli, E., Marra, M. Perazzolo, Basso, C., Calabrese, F., Rea, F.

المصدر: The Journal of Heart and Lung Transplantation ; volume 40, issue 4, page S511 ; ISSN 1053-2498

مصطلحات موضوعية: Transplantation, Cardiology and Cardiovascular Medicine, Pulmonary and Respiratory Medicine, Surgery

الإتاحة: https://doi.org/10.1016/j.healun.2021.01.2063Test
https://api.elsevier.com/content/article/PII:S1053249821020970?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1053249821020970?httpAccept=text/plainTest

المؤلفون: Stefanizzi, P., Martinelli, A., Ferorelli, D., Soldano, S., Marra, M., Dell’Aera, M., Dattoli, V., Vimercati, L., Tafuri, S., Spinelli, G., Amoruso, F., Capodiferro, L., De Crescenzo, I., Rella, M., Furio, A., Nozza, M., Riformato, G., Lattanzio, S., Raspatella, G., Tatone, A., Parnoffi, N.

المصدر: Journal of Hospital Infection ; volume 112, page 42-44 ; ISSN 0195-6701

مصطلحات موضوعية: Infectious Diseases, Microbiology (medical), General Medicine

الإتاحة: https://doi.org/10.1016/j.jhin.2021.03.016Test
https://api.elsevier.com/content/article/PII:S0195670121001134?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0195670121001134?httpAccept=text/plainTest

المؤلفون: Fiorillo, A, Manai, M, Marra, M, Visconti, S, Camoni, L

مصطلحات موضوعية: Settore BIO/04

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______3667::f326a9f0c78cabb705e0a18b1a7b7908Test
https://hdl.handle.net/2108/321122Test

المؤلفون: Pontone G., Guaricci A. I., Fusini L., Baggiano A., Guglielmo M., Muscogiuri G., Volpe A., Abete R., Aquaro G., Barison A., Bogaert J., Camastra G., Carigi S., Carrabba N., Casavecchia G., Censi S., Cicala G., De Cecco C. N., De Lazzari M., Di Giovine G., Di Roma M., Dobrovie M., Focardi M., Gaibazzi N., Gismondi A., Gravina M., Lanzillo C., Lombardi M., Lorenzoni V., Lozano-Torres J., Martini C., Marzo F., Masi A., Memeo R., Moro C., Nese A., Palumbo A., Pavon A. G., Pedrotti P., Marra M. P., Pica S., Pradella S., Presicci C., Rabbat M. G., Raineri C., Rodriguez-Palomares J. F., Sbarbati S., Schoepf U. J., Squeri A., Sverzellati N., Symons R., Tat E., Timpani M., Todiere G., Valentini A., Varga-Szemes A., Masci P. -G., Schwitter J.

المساهمون: Pontone, G, Guaricci, A, Fusini, L, Baggiano, A, Guglielmo, M, Muscogiuri, G, Volpe, A, Abete, R, Aquaro, G, Barison, A, Bogaert, J, Camastra, G, Carigi, S, Carrabba, N, Casavecchia, G, Censi, S, Cicala, G, De Cecco, C, De Lazzari, M, Di Giovine, G, Di Roma, M, Dobrovie, M, Focardi, M, Gaibazzi, N, Gismondi, A, Gravina, M, Lanzillo, C, Lombardi, M, Lorenzoni, V, Lozano-Torres, J, Martini, C, Marzo, F, Masi, A, Memeo, R, Moro, C, Nese, A, Palumbo, A, Pavon, A, Pedrotti, P, Marra, M, Pica, S, Pradella, S, Presicci, C, Rabbat, M, Raineri, C, Rodriguez-Palomares, J, Sbarbati, S, Schoepf, U, Squeri, A, Sverzellati, N, Symons, R, Tat, E, Timpani, M, Todiere, G, Valentini, A, Varga-Szemes, A, Masci, P, Schwitter, J

مصطلحات موضوعية: cardiac magnetic resonance, heart failure, implantable cardioverter-defibrillator, ischemic dilated cardiomyopathy, primary prevention

الوصف: Background: Implantable cardioverter-defibrillator (ICD) therapy is the most effective prophylactic strategy against sudden cardiac death (SCD) in patients with ischemic cardiomyopathy (ICM) and left ventricle ejection fraction (LVEF) ≤35% as detected by transthoracic echocardiograpgy (TTE). This approach has been recently questioned because of the low rate of ICD interventions in patients who received implantation and the not-negligible percentage of patients who experienced SCD despite not fulfilling criteria for implantation. Objectives: The DERIVATE-ICM registry (CarDiac MagnEtic Resonance for Primary Prevention Implantable CardioVerter DebrillAtor ThErapy; NCT03352648) is an international, multicenter, and multivendor study to assess the net reclassification improvement (NRI) for the indication of ICD implantation by the use of cardiac magnetic resonance (CMR) as compared to TTE in patients with ICM. Methods: A total of 861 patients with ICM (mean age 65 ± 11 years, 86% male) with chronic heart failure and TTE-LVEF <50% participated. Major adverse arrhythmic cardiac events (MAACE) were the primary endpoints. Results: During a median follow-up of 1,054 days, MAACE occurred in 88 (10.2%). Left ventricular end-diastolic volume index (HR: 1.007 [95% CI: 1.000-1.011]; P = 0.05), CMR-LVEF (HR: 0.972 [95% CI: 0.945-0.999]; P = 0.045) and late gadolinium enhancement (LGE) mass (HR: 1.010 [95% CI: 1.002-1.018]; P = 0.015) were independent predictors of MAACE. A multiparametric CMR weighted predictive derived score identifies subjects at high risk for MAACE compared with TTE-LVEF cutoff of 35% with a NRI of 31.7% (P = 0.007). Conclusions: The DERIVATE-ICM registry is a large multicenter registry showing the additional value of CMR to stratify the risk for MAACE in a large cohort of patients with ICM compared with standard of care.

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37227329; info:eu-repo/semantics/altIdentifier/wos/WOS:001112389700001; volume:16; issue:11; firstpage:1387; lastpage:1400; numberofpages:14; journal:JACC. CARDIOVASCULAR IMAGING; https://hdl.handle.net/10281/481663Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85164622311

الإتاحة: https://doi.org/10.1016/j.jcmg.2023.03.015Test
https://hdl.handle.net/10281/481663Test

المؤلفون: Marra M., Provenzano C., Cesaria M., Cataldo R., Monteduro A. G., Caricato A. P.

المساهمون: Marra, M., Provenzano, C., Cesaria, M., Cataldo, R., Monteduro, A. G., Caricato, A. P.

مصطلحات موضوعية: bromine vacancie, CsPbBr3 halide perovskite, oxygen incorporation during growth, PLD technique

الوصف: Among all the inorganic perovskites, cesium lead bromide (CsPbBr (Formula presented.)) has gained significant interest due to its stability and remarkable optoelectronic/photoluminescence properties. Because of the influence of deposition techniques, the experimental conditions that play a key role in each need to be addressed. In this context, we present CsPbBr (Formula presented.) films grown by pulsed laser deposition (PLD) and discuss the impact of oxygen stemming from their growth under a reduced vacuum, i.e., as the background atmosphere, rather than from post-growth exposure. In detail, stoichiometric mechano-chemically synthesized targets were prepared for deposition by nanosecond-PLD ((Formula presented.) = 248 nm, (Formula presented.) = 20 ns, room temperature, fluence of 1 J/cm (Formula presented.)) to produce slightly Br-deficient CsPbBr (Formula presented.) films under different background pressure conditions (P (Formula presented.) = 10 (Formula presented.), 10 (Formula presented.) Pa). The characterization results suggest that the presence of oxygen during the deposition of CsPbBr (Formula presented.) can advantageously passivate bromide-vacancy states in all the film thicknesses and reduce losses from emissions. Overall, our findings shed light on the critical role of oxygen, under conditions in which we ruled out other effects related to air exposure, and provide valuable guidelines for potential applications in various optoelectronic devices.

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:001074234100001; volume:11; journal:PROCESSES; https://hdl.handle.net/11587/511869Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85172779098

الإتاحة: https://doi.org/10.3390/pr11092514Test
https://hdl.handle.net/11587/511869Test

المؤلفون: Licaj I., Felice D., Germinario C., Zanotti C., Fiorillo A., Marra M., Rocco M.

المساهمون: Licaj, I, Felice, D, Germinario, C, Zanotti, C, Fiorillo, A, Marra, M, Rocco, M

مصطلحات موضوعية: artificial intelligence, osmotic stress, phytohormones, root, wheat, Settore BIO/04

الوصف: Due to drought stress, durum wheat production in the Mediterranean basin will be severely affected in the coming years. Durum wheat cultivation relies on a few genetically uniform "modern" varieties, more productive but less tolerant to stresses, and "traditional" varieties, still representing a source of genetic biodiversity for drought tolerance. Root architecture plasticity is crucial for plant adaptation to drought stress and the relationship linking root structures to drought is complex and still largely under-explored. In this study, we examined the effect of drought stress on the roots’ characteristics of the “traditional” Saragolla cultivar and the “modern” Svevo. By means of “SmartRoot” software, we demonstrated that drought stress affected primary and lateral roots as well as root hair at different extents in Saragolla and Svevo cultivars. Indeed, we observed that under drought stress Saragolla possibly revamped its root architecture, by significantly increasing the length of lateral roots, and the length/density of root hairs compared to the Svevo cultivar. Scanning Electron Microscopy analysis of root anatomical traits demonstrated that under drought stress a greater stele area and an increase of the xylem lumen size vessel occurred in Saragolla, indicating that the Saragolla variety had a more efficient adaptive response to osmotic stress than the Svevo. Furthermore, for the analysis of root structural data, Artificial Intelligence (AI) algorithms have been used: Their application allowed to predict from root structural traits modified by the osmotic stress the type of cultivar observed and to infer the relationship stress-cultivar type, thus demonstrating that root structural traits are clear and incontrovertible indicators of the higher tolerance to osmotic stress of the Saragolla cultivar. Finally, to obtain an integrated view of root morphogenesis, phytohormone levels were investigated. According to the phenotypic effects, under drought stress,a larger increase in IAA and ABA levels, as well as ...

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37900753; info:eu-repo/semantics/altIdentifier/wos/WOS:001089864200001; volume:14; journal:FRONTIERS IN PLANT SCIENCE; https://hdl.handle.net/2108/343523Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85175379875

الإتاحة: https://doi.org/10.3389/fpls.2023.1241281Test
https://hdl.handle.net/2108/343523Test