المؤلفون: Ferrera C, Vilacosta I, Cabeza B, Cobiella J, Martínez I, Saiz-Pardo Sanz M, Bustos A, Serrano FJ, Maroto L

المصدر: Vascular Health and Risk Management, Vol Volume 16, Pp 203-213 (2020)

مصطلحات موضوعية: aortic intramural hematoma, acute aortic syndrome, diagnosis, Diseases of the circulatory (Cardiovascular) system, RC666-701

الوصف: Carlos Ferrera,1 Isidre Vilacosta,1 Beatriz Cabeza,2 Javier Cobiella,3 Isaac Martínez,4 Melchor Saiz-Pardo Sanz,5 Ana Bustos,2 Francisco Javier Serrano,4 Luis Maroto3 1Department of Cardiology, Hospital Clínico San Carlos, Madrid, Spain; 2Department of Radiology, Hospital Clínico San Carlos, Madrid, Spain; 3Department of Cardiac Surgery, Hospital Clínico San Carlos, Madrid, Spain; 4Department of Vascular Surgery, Hospital Clínico San Carlos, Madrid, Spain; 5Pathology Department, Hospital Clínico San Carlos, Madrid, SpainCorrespondence: Carlos FerreraDepartment of Cardiology, Hospital Clínico San Carlos, Calle Profesor Martín Lagos S/N, Madrid 28040, SpainTel +34 91 330 3149Fax +34 91 330 3142Email carlosferreraduran@gmail.comAbstract: Aortic intramural hematoma (AIH) is an entity within the acute aortic syndrome. Combination of a priori probability, clinical history, laboratory blood test and imaging techniques are the basis for diagnosis of AIH. This review is focused on all aspects related to diagnosis of patients with AIH, from clinical to imaging and analytical.Keywords: aortic intramural hematoma, acute aortic syndrome, diagnosis

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/diagnosing-aortic-intramural-hematoma-current-perspectives-peer-reviewed-article-VHRMTest; https://doaj.org/toc/1178-2048Test

الوصول الحر: https://doaj.org/article/42c2a35d3e3e48fe83bb716b88c18c4fTest

المؤلفون: Pérez, D, Maroto, L, Cobiella, J, Montero, L, Torres, B, Carnero, M, Marti Sanchez, B, Diaz, A, Cuervo, J

المصدر: Value in Health ; volume 25, issue 1, page S26 ; ISSN 1098-3015

مصطلحات موضوعية: Public Health, Environmental and Occupational Health, Health Policy

الإتاحة: https://doi.org/10.1016/j.jval.2021.11.119Test
https://api.elsevier.com/content/article/PII:S1098301521019148?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1098301521019148?httpAccept=text/plainTest

المؤلفون: McInerney, A, Triado-Conte, G, Hernando Salazar Triviño, C, Cruz, A, Jimenez-Quevedo, P, Carnero, M, Gonzalo, N, Cobiella, J, Nuñez-Gil, I, Mejía-Renteria, H, Salinas, P, Macaya, F, Maroto, L, Vilacosta, I, Fernández-Ortiz, A, Escaned, J, Macaya, C, Nombela-Franco, L

المصدر: Oral abstract presentations 1

الإتاحة: https://doi.org/10.1136/heartjnl-2020-ics.8Test

المؤلفون: Mahia, P, Cobiella, J, Carnero, M, Enriquez, D, De Agustin, J.A, Macaya, C, Maroto, L

المصدر: European Heart Journal ; volume 42, issue Supplement_1 ; ISSN 0195-668X 1522-9645

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

الوصف: Background Transapical beating-heart neochord implantation (Neochord) to repair mitral valve regurgitation has been demonstrated to be a safe and effective minimally invasive alternative to open surgical repair in selected patients with mitral leaflet prolapse. Successful neochordae implantation depends on accurate localization of the site of regurgitation and careful assessment of MV morphology. The objective of this study is to demonstrate that 3D-transesophageal echocardiography (3D-TEE) has become a fundamental tool, essential in both the preoperative study and to guide the procedure and for follow-up. Methods All consecutive patients with severe symptomatic DMR due to prolapse or flail of one or both mitral leaflets that underwent the NeoChord procedure between March 2017-Jan 2021 were included. Patients were categorized according to MV anatomy by 3D-TEE; Type A isolated central posterior leaflet prolapse and/or flail, Type B posterior multi-segment prolapse and/or flail, Type C anterior and/or bi-leaflet prolapse or flail, Type D paracommissural prolapse and/or flail and/or significant leaflet and/or annular calcifications. Results 43 patients were included. Median age was 67.7±13.4 y. Median EuroSCOREII 2.7%±1.91. There were 35 Type A patients (81.4%), 4 Type B (9.3%), 1 Type C (2.3%), and 3 Type D (7%). Type A was considered the more favorable morphology. 2D/3D TEE were employed for guiding the device from the apex of the left ventricle across the mitral annulus (Figure 1, A–C), orientation of the tip of the device with regards to the prolapsing segment of the leaflet positioning and leaflet grasping (Figure 1, D, E) and evaluation of the final length and tension of the neochordae to obtain a satisfactory mitral valve competence. (Figure 1, F). Procedural success was achieved in 38 patients (88,4%). 5 patients, 2 type A and 3 type D, underwent conversion to open surgery for immediate failure. 1 high-risk patient considered inoperable died before discharge. At 19 (IQR 13–23) months median ...

الإتاحة: https://doi.org/10.1093/eurheartj/ehab724.085Test
https://academic.oup.com/eurheartj/article-pdf/42/Supplement_1/ehab724.085/41049408/ehab724.085.pdfTest

المؤلفون: Olmos, C., Vilacosta, I., López, J., Sáez, C., Anguita, M., García-Granja, P. E., Sarriá, C., Silva, J., Álvarez Álvarez, Belén, Martínez Monzonís, Maria Amparo, Castillo, J. C., Seijas, J., López-Picado, A., Peral, V., Maroto, L., San Román, J. A.

مصطلحات موضوعية: Gram-Positive Cocci, Adult, Endocarditis, Middle Aged, Adolescent, Follow-Up Studies, Anti-Bacterial Agents, Gram-Positive Bacterial Infections, Clinical Protocols, Humans, Treatment Outcome, Young Adult, Time Factors, Prospective Studies, Aged, resultado del tratamiento, infecciones por bacterias grampositivas, estudios de seguimiento, estudios prospectivos, mediana edad, adulto, antibacterianos, anciano, protocolos clínicos, adulto joven, humanos, factores de tiempo, cocos grampositivos, adolescente, CHUS

الوصف: BACKGROUND: Most serious complications of infective endocarditis (IE) appear in the so-called "critical phase" of the disease, which represents the first days after diagnosis. The majority of patients overcoming the acute phase has a favorable outcome, yet they remain hospitalized for a long period of time mainly to complete antibiotic therapy. The major hypothesis of this trial is that in patients with clinically stable IE and adequate response to antibiotic treatment, without signs of persistent infection, periannular complications or metastatic foci, a shorter antibiotic time period would be as efficient and safe as the classic 4 to 6 weeks antibiotic regimen. METHODS: Multicenter, prospective, randomized, controlled open-label, phase IV clinical trial with a non-inferiority design to evaluate the efficacy of a short course (2 weeks) of parenteral antibiotic therapy compared with conventional antibiotic therapy (4-6 weeks). SAMPLE: patients with IE caused by gram-positive cocci, having received at least 10 days of conventional antibiotic treatment, and at least 7 days after surgery when indicated, without clinical, analytical, microbiological or echocardiographic signs of persistent infection. Estimated sample size: 298 patients. INTERVENTION: Control group: standard duration antibiotic therapy, (4 to 6 weeks) according to ESC guidelines recommendations. Experimental group: short-course antibiotic therapy for 2 weeks. The incidence of the primary composite endpoint of all-cause mortality, unplanned cardiac surgery, symptomatic embolisms and relapses within 6 months after the inclusion in the study will be prospectively registered and compared. CONCLUSIONS: SATIE will investigate whether a two weeks short-course of intravenous antibiotics in patients with IE caused by gram-positive cocci, without signs of persistent infection, is not inferior in safety and efficacy to conventional antibiotic treatment (4-6 weeks). TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04222257 (January 7, 2020). EudraCT ...

العلاقة: https://www.ncbi.nlm.nih.gov/pubmed/32546269Test; http://hdl.handle.net/20.500.11940/16542Test; 39265

الإتاحة: https://doi.org/20.500.11940/16542Test
https://doi.org/10.1186/s12879-020-05132-1Test
https://hdl.handle.net/20.500.11940/16542Test
https://www.ncbi.nlm.nih.gov/pubmed/32546269Test

المؤلفون: Mahia, P, Cobiella, J, Enriquez, D, Carnero, M, Maroto, L, Perez De Isla, L, Macaya, C

المصدر: European Heart Journal ; volume 41, issue Supplement_2 ; ISSN 0195-668X 1522-9645

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

الوصف: Background/Introduction Transapical off-pump mitral valve repair with NeoChord implantation (TOP-MINI) has become applied for patients presenting with severe mitral regurgitation (MR) due to posterior leaflet (PML) prolapse or flail. The procedure is performed under real-time 2D- and 3D-transesophageal echocardiography for both implantation and neochordae tension adjustment allowing real-time monitoring of hemodynamic recovery. Purpose This prospective study sought to evaluate acute safety and efficacy of this innovative, minimally invasive, transcatheter mitral valve repair approach. Methods 33 symptomatic patients patients with severe MR secondary to PML flail/prolapse (March 2017-Dec 2019) were included. Patients were stratified on the basis of the preoperative 3D transesophageal echocardiography assessment of MV morphology: type A, isolated central PML prolapse/flail (25 patients); type B, posterior multisegment prolapse/flail (3 patients); type C and D, anterior or bileaflet prolapse/flail or paracommissural prolapse/flail or any type of disease with the presence of significant leaflet/annular calcifications (5 patients). Type A was considered the more favorable morphology. Results Median age was 67.7±13.4 y. Median EuroSCORE-II 2.7%±1.91. Procedural success was achieved in 28 patients (84,9%). 5 patients, 2 type A and 3 type D, underwent conversion to open surgery for immediate failure. The median number of chords implanted was 3.1±0.6. 1 high-risk patient considered inoperable because of severe comorbidities and extensive annular calcifications died before discharge. Postoperative length of stay was 4.25±1 days. At 12.3±4.9 months median follow-up, MR≤moderate was present in 25 (90%). Overall 1-year survival was 100%. Freedom from reintervention was 97% for overall population. Transthoracic echocardiography at 1 year revealed ventricular reverse remodeling, with a significant decrease in indexed left ventricular end- end-systolic volumes (25.3±6.4 to 21.6±8.2 mL/m2, P<0.001). 92.9% were in ...

الإتاحة: https://doi.org/10.1093/ehjci/ehaa946.1933Test
https://academic.oup.com/eurheartj/article-pdf/41/Supplement_2/ehaa946.1933/42430980/ehaa946.1933.pdfTest

المؤلفون: McInerney, A, Rodés-Cabau, J, Veiga, G, Lopez-Otero, D, Muñoz-Garcia, E, Campelo, F, Oteo, JF, Carnero, M, Tafur Soto, JD, Amat-Santos, I, Travieso, A, Mohammadi, S, Barbanti, M, Cheema, AN, Toggweiler, S, Saia, F, Dabrowski, M, Serra, V, Alfonso, F, Barbosa, H, Regueiro, A, Alperi, A, Ongay, AG, Martinez Cereijo, JM, Muñoz-Garcia, AJ, Matta, A, Arellano-Serrano, C, Barrero, A, Tirado-Conte, G, Gonzalo, N, Sanmartin, XC, de la Torre Hernández, JM, Kalavrouziotis, D, Maroto, L, Forteza-Gil, A, Cobiella, J, Escaned, J, Nombela-Franco, L

المصدر: Oral abstract presentations 2

الإتاحة: https://doi.org/10.1136/heartjnl-2022-ics.14Test

المؤلفون: Gomez Polo, J.C., Vilacosta, I., Martin-Garcia, A.C., Fortuny, E., Fernandez-Perez, C., Garcia-Bouza, M., Carnero, M., Vivas, D., Higueras, J., Cobiella, J., Ferrera, C., Martin-Benitez, J.C., Acedo Diaz-Pache, M.V., Olmos, C., Maroto, L.

المصدر: European Heart Journal ; volume 38, issue suppl_1 ; ISSN 0195-668X 1522-9645

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

الإتاحة: https://doi.org/10.1093/eurheartj/ehx502.p2702Test
http://academic.oup.com/eurheartj/article-pdf/38/suppl_1/ehx502.P2702/19626354/ehx502.P2702.pdfTest

المؤلفون: Cruz Utrilla, A., Vivas, D., Perez-Garcia, C.N., Luque, T., Carnero, M., Maroto, L., Olmos, C., Garcia-Arribas, D., Martinez-Vives, P., Fernandez-Vega, A., Vilacosta, I., Macaya, C.

المصدر: European Heart Journal ; volume 38, issue suppl_1 ; ISSN 0195-668X 1522-9645

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

الإتاحة: https://doi.org/10.1093/eurheartj/ehx501.p510Test
http://academic.oup.com/eurheartj/article-pdf/38/suppl_1/ehx501.P510/19619236/ehx501.P510.pdfTest

المؤلفون: Bautista-Hernandez, V., Barbeito, M. Gonzalez, Vazquez, A., Carnero, M., Sarralde, J. A., Maroto, L., Hornero, F., Canovas, S., Gutierrez, F., Arribas, J. M.

المصدر: The Thoracic and Cardiovascular Surgeon ; 50th Annual Meeting of the German Society for Thoracic and Cardiovascular Surgery (DGTHG) ; ISSN 1439-1902

الإتاحة: https://doi.org/10.1055/s-0041-1725750Test