المؤلفون: Prapon Wilairat, Maria G. Gomez-Lorenzo, Thanat Chookajorn, Kesinee Chotivanich, Krittikorn Kümpornsin, Laura M. Sanz, Cristina de Cozar, Marcus C. S. Lee, Namfon Kotanan, Duangkamon Loesbanluechai, Nicholas J. White, Francisco-Javier Gamo

المصدر: International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss, Pp 186-190 (2021)
International Journal for Parasitology: Drugs and Drug Resistance

مصطلحات موضوعية: Drug, Regular article, Artemisinins, media_common.quotation_subject, Plasmodium falciparum, Protozoan Proteins, Drug resistance, Infectious and parasitic diseases, RC109-216, Pharmacology, Lumefantrine, Antimalarials, chemistry.chemical_compound, Isobologram, parasitic diseases, medicine, Humans, Pharmacology (medical), Artemether, Malaria, Falciparum, Artemisinin, media_common, biology, business.industry, biology.organism_classification, medicine.disease, Malaria, Infectious Diseases, chemistry, Parasitology, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d3e099e19347efd4515052b596b009Test
http://www.sciencedirect.com/science/article/pii/S2211320721000488Test

المؤلفون: Madeline R. Luth, Manuel Llinás, Marcus C. S. Lee, Eva S. Istvan, Elizabeth A. Winzeler, Edward Owen, Frances Rocamora, Krittikorn Kümpornsin, Nimisha Mittal, Krypton Carolino, Purva Gupta, Emma F. Carpenter, Jaeson Calla, Daniel E. Goldberg, Erika Sasaki, Sabine Ottilie

المصدر: ACS Infectious Diseases. 7:811-825

مصطلحات موضوعية: 0301 basic medicine, Genetics, biology, Drug discovery, Phenotypic screening, 030106 microbiology, Plasmodium falciparum, Drug resistance, medicine.disease, biology.organism_classification, Multiple drug resistance, 03 medical and health sciences, 030104 developmental biology, Infectious Diseases, medicine, Gene, Chemical genetics, Malaria

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d107534a11d90fbd12eb922babae0441Test
https://doi.org/10.1021/acsinfecdis.0c00676Test

المؤلفون: Deyun Qiu, Jinxin V. Pei, James E. O. Rosling, Dongdi Li, Yi Xue, Jocelyn Sietsma Penington, Krittikorn Kümpornsin, Yi Tong Vincent Aw, Jessica Yi Han Aw, Heath Hasemer, Adelaide S. M. Dennis, Melanie C. Ridgway, Anthony T. Papenfuss, Marcus C. S. Lee, Giel G. van Dooren, Kiaran Kirk, Adele M. Lehane

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::60fbce80d8893b9d3de3dceeed4f1978Test
https://doi.org/10.1101/2022.01.11.475938Test

المؤلفون: Jennifer A. Yang, Bing Yu Zou, Frances Rocamora, Edgar Vigil, Prianka Kumar, Nina F. Gnädig, Alan F. Cowman, David A. Fidock, Roy Williams, Trevor Johnson, Madeline R. Luth, Danushka S. Marapana, Dylan Hutson, Marcus C. S. Lee, Tilla S. Worgall, Jianbo Huang, Gregory M. Goldgof, Gregory LaMonte, T. R. Santha Kumar, Jennifer K. Thompson, Timothy J. Egan, Roxanne Mohunlal, Sabine Ottilie, Dionicio Siegel, Elizabeth A. Winzeler, Andrea L. Cheung

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature communications, vol 11, iss 1

مصطلحات موضوعية: 0301 basic medicine, ved/biology.organism_classification_rank.species, Protozoan Proteins, General Physics and Astronomy, Synthetic lethality, Endoplasmic Reticulum, Plasmodium, Mass Spectrometry, chemistry.chemical_compound, 2.1 Biological and endogenous factors, 2.2 Factors relating to the physical environment, Aetiology, lcsh:Science, Chromatography, High Pressure Liquid, Chromatography, Multidisciplinary, Secretory Pathway, biology, Brefeldin A, Cell biology, Infectious Diseases, 5.1 Pharmaceuticals, High Pressure Liquid, HIV/AIDS, Development of treatments and therapeutic interventions, medicine.symptom, Infection, Science, 030106 microbiology, Saccharomyces cerevisiae, Plasmodium falciparum, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Antimalarials, Inhibitory Concentration 50, Rare Diseases, Target identification, parasitic diseases, medicine, Secretion, Model organism, Gene, Secretory pathway, ved/biology, Endoplasmic reticulum, Autophagy, General Chemistry, biology.organism_classification, Malaria, Vector-Borne Diseases, Good Health and Well Being, 030104 developmental biology, chemistry, Mechanism of action, Pyrazoles, lcsh:Q

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b18290350407667761814a3f37b90a3Test
https://doaj.org/article/30325ebc8f1440eb95a7ef787cbdca69Test

المؤلفون: Johanna Hoshizaki, Hannah Jagoe, Marcus C. S. Lee

مصطلحات موضوعية: Clinical Microbiology, Medical Bacteriology, Medical Infection Agents (incl. Prions), Medical Virology, malaria, reporter genes, fluorescence, CRISPR/Cas9, Plasmodium falciparum

العلاقة: https://figshare.com/articles/dataset/DataSheet_1_Efficient_generation_of_mNeonGreen_Plasmodium_falciparum_reporter_lines_enables_quantitative_fitness_analysis_pdf/21128467Test

الإتاحة: https://doi.org/10.3389/fcimb.2022.981432.s001Test
https://figshare.com/articles/dataset/DataSheet_1_Efficient_generation_of_mNeonGreen_Plasmodium_falciparum_reporter_lines_enables_quantitative_fitness_analysis_pdf/21128467Test

المؤلفون: Jacquin C. Niles, John Okombo, Dyann F. Wirth, Eva S. Istvan, Daniel E. Goldberg, Ian H. Gilbert, David A. Fidock, Brice Campo, Barbara Forte, Koen J. Dechering, Francisco-Javier Gamo, Sabine Ottilie, Amanda K. Lukens, Susan Wyllie, Elizabeth A. Winzeler, Case W. McNamara, Marcus C. S. Lee, Miles G. Siegel, Beatriz Baragaña, Charisse Flerida A. Pasaje, Andy Plater

المصدر: ACS Infectious Diseases

مصطلحات موضوعية: Drug, Prioritization, Plasmodium, Computer science, Drug discovery, molecular targets, media_common.quotation_subject, Phenotypic screening, malaria, Computational biology, Antimalarials, Infectious Diseases, Drug Discovery, Perspective, Molecular targets, Humans, media_common, Plasmodium species

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecaca747c60cc11a781350a28e4da460Test
https://pubmed.ncbi.nlm.nih.gov/34523908Test

المؤلفون: Johanna, Hoshizaki, Marcus C S, Lee

المصدر: Nature reviews. Microbiology. 19(8)

مصطلحات موضوعية: Transcription, Genetic, Sequence Analysis, RNA, Plasmodium falciparum, Protozoan Proteins, Chromosome Mapping, Humans, Malaria, Falciparum, Transcription Initiation Site, Promoter Regions, Genetic, Toxoplasma, Toxoplasmosis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::d1c1584d2e279736f209aa9d041233abTest
https://pubmed.ncbi.nlm.nih.gov/34083794Test

المؤلفون: Frances, Rocamora, Purva, Gupta, Eva S, Istvan, Madeline R, Luth, Emma F, Carpenter, Krittikorn, Kümpornsin, Erika, Sasaki, Jaeson, Calla, Nimisha, Mittal, Krypton, Carolino, Edward, Owen, Manuel, Llinás, Sabine, Ottilie, Daniel E, Goldberg, Marcus C S, Lee, Elizabeth A, Winzeler

المصدر: ACS Infectious Diseases

مصطلحات موضوعية: mitochondria, Antimalarials, drug resistance, transporter, Mutation, Plasmodium falciparum, Drug Resistance, malaria, Humans, Article, Malaria, drug discovery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::01a44b4b704872479782475a82692856Test
https://pubmed.ncbi.nlm.nih.gov/33715347Test

المؤلفون: Marcus C. S. Lee, Jose Juan Lopez-Rubio, Scott E. Lindner, Manuel Llinás

المصدر: Briefings in Functional Genomics

مصطلحات موضوعية: Plasmodium, malaria, Computational biology, Gene Deletions, 03 medical and health sciences, Genome editing, CRISPR-Associated Protein 9, medicine, genome editing, CRISPR, CRISPR/Cas9, 030304 developmental biology, Gene Editing, Review Paper, 0303 health sciences, biology, 030306 microbiology, Cas9, biology.organism_classification, medicine.disease, 3. Good health, Gene Expression Regulation, parasite, CRISPR-Cas Systems, Single point, gene regulation, apicomplexan, Functional genomics, Malaria, RNA, Guide, Kinetoplastida

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14af622d3eb9bb16c0eb4944134c191Test
https://doi.org/10.1093/bfgp/elz012Test

المؤلفون: Marcus C. S. Lee, Edward Owen, James M. Murithi, Kerry McGowen, Beatriz Baragaña, Madeline R. Luth, Emma F. Carpenter, Jacquin C. Niles, Chris Walpole, Manu Vanaerschot, Rebecca E. K. Mandt, Sabine Ottilie, Ian H. Gilbert, Avinash S. Punekar, Charisse Flerida A. Pasaje, Krittikorn Kümpornsin, Aslı Akidil, João Pedro Pisco, Kelly Rubiano, Nimisha Mittal, David A. Fidock, Robert L. Summers, De Lin, Andy Plater, Sharon M. Shepherd, Elizabeth A. Winzeler, A. Hazel Dilmore, Andrew M. Shepherd, Amanda K. Lukens, Dyann F. Wirth, Madalyn Won, Josefine Striepen, Justin Munro, Manuel Llinás

المصدر: Cell Chemical Biology. 29:191-201.e8

مصطلحات موضوعية: Models, Molecular, Plasmodium falciparum, Clinical Biochemistry, Druggability, Acetate-CoA Ligase, Biochemistry, Antimalarials, chemistry.chemical_compound, Parasitic Sensitivity Tests, Drug Discovery, Chemogenomics, Humans, Epigenetics, Enzyme Inhibitors, Molecular Biology, Pharmacology, Gene knockdown, Molecular Structure, biology, Acetyl—CoA synthetase, biology.organism_classification, Malaria, Histone, chemistry, Acetylation, biology.protein, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e3028ee2d6c74bf0739d4ebecac7ebTest
https://doi.org/10.1016/j.chembiol.2021.07.010Test