يعرض 1 - 10 نتائج من 50 نتيجة بحث عن '"Marco Arena"', وقت الاستعلام: 1.00s تنقيح النتائج
  1. 1
    دورية أكاديمية

    المصدر: Reviews in Cardiovascular Medicine, Vol 24, Iss 2, p 62 (2023)

    الوصف: Background: Recently, questions around the efficacy and effectiveness of Fractional Flow Reserve (FFR) have arisen in various clinical settings. Methods: The Clinical Outcome of FFR-guided Revascularization Strategy of Coronary Lesions (HALE-BOPP) study is an investigator-initiated, multicentre, international prospective study enrolling patients who underwent FFR measurement on at least one vessel. In accordance with the decision-making workflow and treatment, the vessels were classified in three subgroups: (i) angio-revascularized, (ii) FFR-revascularized, (iii) FFR-deferred. The primary endpoint was the occurrence of target vessel failure (TVF, cardiac death, target vessel myocardial infarction and ischemia-driven target vessel revascularization). The analysis was carried out at vessel- and patient-level. Results: 1305 patients with 2422 diseased vessels fulfilled the criteria for the present analysis. Wire-related pitfalls and transient adenosine-related side effects occurred in 0.8% (95% CI: 0.4%–1.4%) and 3.3% (95% CI: 2.5%–4.3%) of cases, respectively. In FFR-deferred vessels, the overall incidence rate of TVF was 0.024 (95% CI: 0.019–0.031) lesion/year. After a median follow-up of 3.6 years, the occurrence of TVF was 6%, 7% and 11.7% in FFR-deferred, FFR-revascularized and angio-revascularized vessels, respectively. Compared to angio-revascularized vessels, FFR-guided vessels (both FFR-revascularized and FFR-deferred vessels) showed a lower TVF incidence rate lesion/year (0.029, 95% CI: 0.024–0.034 vs. 0.049, 95% CI: 0.040–0.061 respectively, p = 0.0001). The result was consistent after correction for confounding factors and across subgroups of clinical interest. The patient-level analysis confirmed the lower occurrence of TVF in negative-FFR vs. positive-FFR subgroups. Conclusions: In a large prospective observational study, an FFR-based strategy for the deferral of coronary lesions is a reliable and safe tool, associated with good outcomes. Clinical Trial Registration: NCT03079739.

    وصف الملف: electronic resource

  2. 2
    دورية أكاديمية
  3. 3
    دورية أكاديمية

    المؤلفون: Biscaglia, Simone, Guiducci, Vincenzo, Escaned, Javier, Moreno, Raul, Lanzilotti, Valerio, Santarelli, Andrea, Cerrato, Enrico, Sacchetta, Giorgio, Jurado-Roman, Alfonso, Menozzi, Alberto, Amat Santos, Ignacio, Díez Gil, José Luis, Ruozzi, Marco, Barbierato, Marco, Fileti, Luca, Picchi, Andrea, Lodolini, Veronica, Biondi-Zoccai, Giuseppe, Maietti, Elisa, Pavasini, Rita, Cimaglia, Paolo, Tumscitz, Carlo, Erriquez, Andrea, Penzo, Carlo, Colaiori, Iginio, Pignatelli, Gianluca, Casella, Gianni, Iannopollo, Gianmarco, Menozzi, Mila, Varbella, Ferdinando, Caretta, Giorgio, Dudek, Dariusz, Barbato, Emanuele, Tebaldi, Matteo, Campo, Gianluca, FIRE Trial Investigators: Gianluca Campo, Simone Biscaglia, Carlo Penzo, Camilla Matese, Elisa Venturoli, Beatrice De Carolis, Daniele Maio, Martina Viola, Elisa Mosele, Chiara Manzalini, Giorgio Sacchetta, Marco Contarini, Claudia Artale, Vincenzo Guiducci, Gianluca Pignatelli, Iginio Colaiori, Sergio Musto D'Amore, Davide Bosi, Linda Valli, Rosa De Mola, Andrea Santarelli, Mila Menozzi, Caterina Cavazza, Luca Fileti, Andrea Rubboli, Matteo Aquilina, Marco Balducelli, Carolina Moretti, Ferdinando Varbella, Enrico Cerrato, Francesco Tomassini, Cristina Rolfo, Alfonso Franzè, Giulio Piedimonte, Greca Zanda, Luca Lo Savio, Gianni Casella, Giampiero Nobile, Alessandro Capecchi, Valerio Lanzilotti, Gianmarco Iannopollo, Roberto Verardi, Barbara Coutsoumbas, Flavio Maffia, Francesco Giannini, Rossella Ruggiero, Vincenzo Argentino, Dino Bonomo, Diego Milazzo, Gerlando Pilato, Giovanni Vaccaro, Ilenia Di Liberto, Marco Ruozzi, Paolo Magnavacchi, Daniele Iaccarino, Pietro Landino, Alfonsina Corbisiero, Domenico Di Girolamo, Giuseppe Vadalà, Giunta Rocco, Trovato Graziano, Alberto Menozzi, Giorgio Caretta, Marco Arena, Giuseppe Andò, Francesco Costa, Giampiero Vizzari, Vittorio Virga, Francesco Saporito, Michele Pighi, Andrea Mainardi, Francesco Della Mora, Roberto Scarsini, Flavio Ribichini, Andrea Picchi, Alberto Massoni, Ugo Limbruno, Andrea Berni, Stefano Rigattieri, Marco Barbierato, Gianpiero D'Amico, Francesco Gallo, Maurizio D'Amico, Alfonso Gambino, Paolo Calabrò, Fabio Fimiani, Elisabetta Moscarella, Silvio Coletta, Michele De Benedictis, Marco Pavani, Umberto Barbero, Cinzia Moncalvo, Javier Escaned Barbosa, Carlos Vergará, Angela McInerney, Hernán Mejia, Oscar Vedia, Ana Gomez, Raul Moreno, Juan Caro-Codon, Virginia Fernandez-Figares, Guillermo Galeote, Santiago Jimenez-Valero, Alfonso Jurado-Roman, María Labrador, Guiomar Mediavilla, Sandra Rosillo, Francisco Fernandez-Aviles, Enrique Gutierrez Ibañes, Sandra Vazquez, Andres Iñiguez Romo, Guillermo Bastos Fernández, Alberto Ortiz Sáez, Jose Antonio Baz Alonso, Antonio Alejandro de Miguel Castro, Víctor Alfonso Jiménez Díaz, Saleta Fernández Barbeira, Rodrigo Estévez Loureiro, Rocío González Ferreiro, Pablo Juan Salvadores, Ana Isabel Ferrero Martínez, Sonia Soto Fernández, María José Rodríguez Pérez, María Pena Martínez, Fernando Lozano Ruiz-Poveda, Maria Lopez Lluva, Jose Abellan, Ignacio Perez, José Luis Díez Gil, Vicente Jimenez Cruz, Bernabé López Ledesma, Raymundo Ocaranza-Sanchez, Melisa Santás Álvarez, Jeremias Bayón Lorenzo, Rubén Vila Abelleira, Alba Abellás Sequeirós, Rubén Vila, Susana Miranda, Ramiro Trillo Nouche, Diego Lopez Otero, Ana Belen Cid Alvarez, Juan Carlos Santamaria Pena, Diana Pereiro Montes, Ramón Calviño Santos, Jose Manuel Vazquez Rodriguez, Elena Paz Misiego, Ignacio J Amat Santos, Alfredo Redondo, Alberto Campo, Julio Peral, Carlos Baladron, María José Coya, Dariusz Dudek, Dawid Giszterowicz, Wojciech Dobrowolski, Marcin Nosal, Rafał Marosz, Piotr Wilusz, Jarosław Paździerz, Piotr Żywiec, Sławomir Szynal, Stefania Corsi, Marzia Sivieri, Matteo Tebaldi, Javier Escaned, Emanuele Barbato, Andres Iniguez Romo, Ramon Calvino Santos, José Luis Diez Gil, Marco Manfrini, Carlo Tumscitz, Rita Pavasini, Paolo Cimaglia, Elisa Maietti, Stefano Volpato, Anna Zanetti, Nicola Pasenti, Greta Carraro, Giuseppe Biondi Zoccai, Andrea Erriquez, Filippo Maria Verardi, Serena Caglioni, Andrea Marrone, Ennio Scollo, Antonella Scala, Matteo Arzenton, Graziella Pompei, Nicola Bianchi, Roberta Campana, Marta Cocco, Assunta Di Domenico, Federico Marchini, Michele Trichilo, Federico Sanguettoli, Davide Scancarello, Claudio Farina, Veronica Lodolini, Sara Fernandez, Beata Chęcińska-Tokarz

    المساهمون: Biscaglia, Simone, Guiducci, Vincenzo, Escaned, Javier, Moreno, Raul, Lanzilotti, Valerio, Santarelli, Andrea, Cerrato, Enrico, Sacchetta, Giorgio, Jurado-Roman, Alfonso, Menozzi, Alberto, Amat Santos, Ignacio, Díez Gil, José Lui, Ruozzi, Marco, Barbierato, Marco, Fileti, Luca, Picchi, Andrea, Lodolini, Veronica, Biondi-Zoccai, Giuseppe, Maietti, Elisa, Pavasini, Rita, Cimaglia, Paolo, Tumscitz, Carlo, Erriquez, Andrea, Penzo, Carlo, Colaiori, Iginio, Pignatelli, Gianluca, Casella, Gianni, Iannopollo, Gianmarco, Menozzi, Mila, Varbella, Ferdinando, Caretta, Giorgio, Dudek, Dariusz, Barbato, Emanuele, Tebaldi, Matteo, Campo, Gianluca, FIRE Trial Investigators: Gianluca Campo, Matese, Camilla, Venturoli, Elisa, Beatrice De Carolis, Maio, Daniele, Viola, Martina, Mosele, Elisa, Manzalini, Chiara, Contarini, Marco, Artale, Claudia, Sergio Musto D'Amore, Bosi, Davide, Valli, Linda, Rosa De Mola, Cavazza, Caterina, Rubboli, Andrea, Aquilina, Matteo, Balducelli, Marco, Moretti, Carolina, Tomassini, Francesco, Rolfo, Cristina, Franzè, Alfonso, Piedimonte, Giulio, Zanda, Greca, Luca Lo Savio, Nobile, Giampiero, Capecchi, Alessandro, Verardi, Roberto, Coutsoumbas, Barbara, Maffia, Flavio, Giannini, Francesco, Ruggiero, Rossella, Argentino, Vincenzo, Bonomo, Dino, Milazzo, Diego, Pilato, Gerlando, Vaccaro, Giovanni, Ilenia Di Liberto, Magnavacchi, Paolo, Iaccarino, Daniele, Landino, Pietro, Corbisiero, Alfonsina, Domenico Di Girolamo, Vadalà, Giuseppe, Rocco, Giunta, Graziano, Trovato, Arena, Marco, Andò, Giuseppe

    الوصف: Background: The benefit of complete revascularization in older patients (≥75 years of age) with myocardial infarction and multivessel disease remains unclear. Methods: In this multicenter, randomized trial, we assigned older patients with myocardial infarction and multivessel disease who were undergoing percutaneous coronary intervention (PCI) of the culprit lesion to receive either physiology-guided complete revascularization of nonculprit lesions or to receive no further revascularization. Functionally significant nonculprit lesions were identified either by pressure wire or angiography. The primary outcome was a composite of death, myocardial infarction, stroke, or any revascularization at 1 year. The key secondary outcome was a composite of cardiovascular death or myocardial infarction. Safety was assessed as a composite of contrast-associated acute kidney injury, stroke, or bleeding. Results: A total of 1445 patients underwent randomization (720 to receive complete revascularization and 725 to receive culprit-only revascularization). The median age of the patients was 80 years (interquartile range, 77 to 84); 528 patients (36.5%) were women, and 509 (35.2%) were admitted for ST-segment elevation myocardial infarction. A primary-outcome event occurred in 113 patients (15.7%) in the complete-revascularization group and in 152 patients (21.0%) in the culprit-only group (hazard ratio, 0.73; 95% confidence interval [CI], 0.57 to 0.93; P = 0.01). Cardiovascular death or myocardial infarction occurred in 64 patients (8.9%) in the complete-revascularization group and in 98 patients (13.5%) in the culprit-only group (hazard ratio, 0.64; 95% CI, 0.47 to 0.88). The safety outcome did not appear to differ between the groups (22.5% vs. 20.4%; P = 0.37). Conclusions: Among patients who were 75 years of age or older with myocardial infarction and multivessel disease, those who underwent physiology-guided complete revascularization had a lower risk of a composite of death, myocardial infarction, stroke, or ischemia-driven ...

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37634150; volume:389; issue:10; firstpage:889; lastpage:898; numberofpages:10; journal:THE NEW ENGLAND JOURNAL OF MEDICINE; https://hdl.handle.net/11570/3273368Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85171177021

  4. 4

    الوصف: In the last decades several Conditional Cash Transfers (CCTs) have been implemented to interrupt the intergenerational transmission of poverty. More recently, they have also been used as a policy response to provide support to households hit by the COVID crisis. CCTs are being deployed as a development tool to reduce local communities’ vulnerability, increasing their resilience and capacity to adapt. In this context, this paper investigates if CCTs can reduce vulnerability to climate change by increasing the adaptative capacity of local communities. Indeed, while some literature has found that CCTs can reduce specific dimensions of vulnerability to socio-economic shocks, we argue that more research is necessary to understand their impact on vulnerability to climate change. Empirically, we use a panel of household survey data collected in Colombia in 2002 and 2006. We employ a difference-in-differences approach to analyse the impact of the CCT programme Familia en Acción (FA) CCTs on rural households. We consider seven components of vulnerability linked to climate change aggregated in an index: wealth, health, access to information, access to basic facilities, financial vulnerability, resilience to natural disasters, and nutrition. Our results differ from previous research and indicate that CCTs provided by the FA program do not decrease vulnerability to climate change. This finding suggests that CCTs are not a universal solution to reducing vulnerability to climate change and may be ineffective in specific contexts. The literature often assumes that CCTs can have a mitigating effect on vulnerability to climate change. Our research shows that in the context of Colombia, this assumption is incorrect.The idea that providing monthly payments to households can reduce vulnerability to climate change should be considered with caution, given limited empirical evidence.Policy makers and scholars should consider the multidimensional nature of vulnerability and design targeted interventions and avoid considering CCTs as a panacea to all aspects of vulnerability to climate change.Our models show that the FA programme failed to have a significant impact in reducing vulnerability to climate change using several different specifications. We show that CCTs do not have an impact on numerous essential components such as wealth, health, access to infrastructure, information and knowledge, financial coping mechanisms, food consumption, and exposure to natural disasters. The literature often assumes that CCTs can have a mitigating effect on vulnerability to climate change. Our research shows that in the context of Colombia, this assumption is incorrect. The idea that providing monthly payments to households can reduce vulnerability to climate change should be considered with caution, given limited empirical evidence. Policy makers and scholars should consider the multidimensional nature of vulnerability and design targeted interventions and avoid considering CCTs as a panacea to all aspects of vulnerability to climate change. Our models show that the FA programme failed to have a significant impact in reducing vulnerability to climate change using several different specifications. We show that CCTs do not have an impact on numerous essential components such as wealth, health, access to infrastructure, information and knowledge, financial coping mechanisms, food consumption, and exposure to natural disasters.

  5. 5
  6. 6
  7. 7

    المصدر: Journal of cardiovascular medicine (Hagerstown, Md.). 23(2)

    الوصف: AIMS We assessed a combined strategy of fractional flow reserve (FFR) plus angiography in stratifying cardiovascular risk in patients with type 1 myocardial infarction (T1MI) or type 2 (T2MI) non-ST elevation acute myocardial infarction (NSTEMI). METHODS A cohort of 150 NSTEMI patients were prospectively studied. Clinical and angiographic features guided the identification of T1MI vs T2MI and the treatment of culprit lesions. Subsequently, T1MI patients underwent FFR evaluation of nonculprit stenoses. In T2MI patients all angiographically significant stenoses were evaluated by FFR. FFR

  8. 8

    المصدر: 2021 IEEE International Symposium on Inertial Sensors and Systems (INERTIAL).

    الوصف: This paper examines the position precision of purely inertial navigation using an array of redundant, low-cost MEMS sensors. A carefully designed IMU is used to perform navigation experiments and to analyze the benefits of a sensor array over a single sensor in practice. As our experimental results show, navigation can be improved significantly by calibrating the IMU device regarding scale factors, offsets and cross-axis sensitivity. By comparing predicted navigation error and experimental results it is shown that gyroscope angle random walk and bias instability are dominant and therefore can be used to estimate naviaation performance. The latter improves roughly by a factor of $\sqrt{14}$ when using an array of 14 devices instead of a single one. A Kalman Filter with motion constraints minimizes the error when estimating positions.

  9. 9
    دورية أكاديمية

    المصدر: Ecological Indicators, Vol 159, Iss , Pp 111654- (2024)

    الوصف: The UN 2030 Agenda for Sustainable Development Goal 15, termed Life on Land, is monitored by indicators and sub-indicators that largely deal with forest extent. In countries with structurally complex and species-rich forests, indicators and sub-indicators of forest quality are also needed to effectively monitor and sustain ecological integrity. The goal of the paper is to demonstrate the use of complementary sub-indicators of forest quality for SDG15 reporting and conservation planning. Our objective is to apply these sub-indicators within Colombia, Ecuador, and Peru and evaluate spatial patterns and trends over time as a basis for revealing how the results complement the official indicators of forest extent and forest extent in protected areas in informing conservation. The sub-indicators of forest quality quantify naturalness, riparian forest, forest structure and integrity, forest fragmentation, and forest connectivity. We quantified change during 2000–2021 in these metrics and highlighted insights gained from the complementary sub-indicators of forest quality relative to the official sub-indicators based on forest extent,Forests covered about 60–70% of the forested ecoregions in each country in 2000 and this proportion declined in all three countries by approximately 4% by 2021. Only a subset of the forested area was of high forest quality. Natural forests represented about 40% of forests in Colombian and Ecuador in 2000 and 50% in Peru. Those proportions declined: by 6.3% in Colombia, 6.5% in Ecuador, and 3.4% in Peru. Even less of the forested area was Core Forest in 2013; less than 28% among countries. During 2013–2021, the proportion of forest that was Core decreased by 2.3% in Colombia, 4.5% in Ecuador, and 6.7% in Peru. Connected Forests were about 17–22% of forests among the countries in 2013 and declined 10.4% in Colombia, 1.6% in Ecuador, and 3.8% in Peru by 2021. Forests high in forest structure were 10–18% of forests in 2012 among the countries and increased by 1.1–2% by 2021. Forests of high integrity were 7–13% of forests in 2012 and increased by1.4–2% by 2021. Riparian forests represented less than about 7–9% among the countries and declined by 0.6–1.3% by 2021. Thus, the area of highly quality forest across the countries was substantially less than full forest extent and high-quality forest declined at a higher rate than forest extent during 2000–2021. Forest structure and integrity did increase slightly over this time period.Our results for trends in forest naturalness, riparian association, within stand structure, fragmentation, and connectivity demonstrate how consideration of forest quality provides a much stronger basis for evaluating success in meeting SDG15 targets than consideration of forest extent alone.

    وصف الملف: electronic resource

  10. 10
    دورية أكاديمية

    المساهمون: The Pennsylvania State University CiteSeerX Archives

    الوصف: 2007 This Working Paper should not be reported as representing the views of the IMF. The views expressed in this Working Paper are those of the author(s) and do not necessarily represent those of the IMF or IMF policy. Working Papers describe research in progress by the author(s) and are published to elicit comments and to further debate. This paper exploits a panel dataset comprising 1,565 banks in 20 emerging countries during 1989-2001 and compares the response of the volume of loans and the rates on loans and deposits to various measures of monetary conditions across domestic and foreign banks. It also looks for systematic differences in the behavior of domestic and foreign banks during periods of financial distress and tranquil times. Using differences in bank ownership as a proxy for financial constraints, the paper finds weak evidence that foreign banks have a lower sensitivity of credit to monetary conditions relative to their domestic competitors, with the differences driven by banks with lower asset liquidity and/or capitalization. The lending and deposit rates of foreign banks tend to be smoother during periods of financial distress. However, the differences across domestic and foreign banks do not

    وصف الملف: application/pdf