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  1. 1
    دورية أكاديمية

    المؤلفون: Nagaraj, Gayathri, Vinayak, Shaveta, Khaki, Ali Raza, Sun, Tianyi, Kuderer, Nicole M, Aboulafia, David M, Acoba, Jared D, Awosika, Joy, Bakouny, Ziad, Balmaceda, Nicole B, Bao, Ting, Bashir, Babar, Berg, Stephanie, Bilen, Mehmet A, Bindal, Poorva, Blau, Sibel, Bodin, Brianne E, Borno, Hala T, Castellano, Cecilia, Choi, Horyun, Deeken, John, Desai, Aakash, Edwin, Natasha, Feldman, Lawrence E, Flora, Daniel B, Friese, Christopher R, Galsky, Matthew D, Gonzalez, Cyndi J, Grivas, Petros, Gupta, Shilpa, Haynam, Marcy, Heilman, Hannah, Hershman, Dawn L, Hwang, Clara, Jani, Chinmay, Jhawar, Sachin R, Joshi, Monika, Kaklamani, Virginia, Klein, Elizabeth J, Knox, Natalie, Koshkin, Vadim S, Kulkarni, Amit A, Kwon, Daniel H, Labaki, Chris, Lammers, Philip E, Lathrop, Kate I, Lewis, Mark A, Li, Xuanyi, de Lima Lopes, Gilbert, Lyman, Gary H, Makower, Della F, Mansoor, Abdul-Hai, Markham, Merry-Jennifer, Mashru, Sandeep H, McKay, Rana R, Messing, Ian, Mico, Vasil, Nadkarni, Rajani, Namburi, Swathi, Nguyen, Ryan H, Nonato, Taylor Kristian, O'Connor, Tracey Lynn, Panagiotou, Orestis A, Park, Kyu, Patel, Jaymin M, Patel, Kanishka GopikaBimal, Peppercorn, Jeffrey, Polimera, Hyma, Puc, Matthew, Rao, Yuan James, Razavi, Pedram, Reid, Sonya A, Riess, Jonathan W, Rivera, Donna R, Robson, Mark, Rose, Suzanne J, Russ, Atlantis D, Schapira, Lidia, Shah, Pankil K, Shanahan, M Kelly, Shapiro, Lauren C, Smits, Melissa, Stover, Daniel G, Streckfuss, Mitrianna, Tachiki, Lisa, Thompson, Michael A, Tolaney, Sara M, Weissmann, Lisa B, Wilson, Grace, Wotman, Michael T, Wulff-Burchfield, Elizabeth M, Mishra, Sanjay, French, Benjamin, Warner, Jeremy L, Lustberg, Maryam B, Accordino, Melissa K, Shah, Dimpy P

    الوصف: BackgroundLimited information is available for patients with breast cancer (BC) and coronavirus disease 2019 (COVID-19), especially among underrepresented racial/ethnic populations.MethodsThis is a COVID-19 and Cancer Consortium (CCC19) registry-based retrospective cohort study of females with active or history of BC and laboratory-confirmed severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection diagnosed between March 2020 and June 2021 in the US. Primary outcome was COVID-19 severity measured on a five-level ordinal scale, including none of the following complications, hospitalization, intensive care unit admission, mechanical ventilation, and all-cause mortality. Multivariable ordinal logistic regression model identified characteristics associated with COVID-19 severity.Results1383 female patient records with BC and COVID-19 were included in the analysis, the median age was 61 years, and median follow-up was 90 days. Multivariable analysis revealed higher odds of COVID-19 severity for older age (aOR per decade, 1.48 [95% CI, 1.32-1.67]); Black patients (aOR 1.74; 95 CI 1.24-2.45), Asian Americans and Pacific Islander patients (aOR 3.40; 95 CI 1.70-6.79) and Other (aOR 2.97; 95 CI 1.71-5.17) racial/ethnic groups; worse ECOG performance status (ECOG PS ≥2: aOR, 7.78 [95% CI, 4.83-12.5]); pre-existing cardiovascular (aOR, 2.26 [95% CI, 1.63-3.15])/pulmonary comorbidities (aOR, 1.65 [95% CI, 1.20-2.29]); diabetes mellitus (aOR, 2.25 [95% CI, 1.66-3.04]); and active and progressing cancer (aOR, 12.5 [95% CI, 6.89-22.6]). Hispanic ethnicity, timing, and type of anti-cancer therapy modalities were not significantly associated with worse COVID-19 outcomes. The total all-cause mortality and hospitalization rate for the entire cohort was 9% and 37%, respectively however, it varied according to the BC disease status.ConclusionsUsing one of the largest registries on cancer and COVID-19, we identified patient and BC-related factors associated with worse COVID-19 outcomes. After adjusting for baseline characteristics, underrepresented racial/ethnic patients experienced worse outcomes compared to non-Hispanic White patients.FundingThis study was partly supported by National Cancer Institute grant number P30 CA068485 to Tianyi Sun, Sanjay Mishra, Benjamin French, Jeremy L Warner; P30-CA046592 to Christopher R Friese; P30 CA023100 for Rana R McKay; P30-CA054174 for Pankil K Shah and Dimpy P Shah; KL2 TR002646 for Pankil Shah and the American Cancer Society and Hope Foundation for Cancer Research (MRSG-16-152-01-CCE) and P30-CA054174 for Dimpy P Shah. REDCap is developed and supported by Vanderbilt Institute for Clinical and Translational Research grant support (UL1 TR000445 from NCATS/NIH). The funding sources had no role in the writing of the manuscript or the decision to submit it for publication.Clinical trial numberCCC19 registry is registered on ClinicalTrials.gov, NCT04354701.

    وصف الملف: application/pdf

  2. 2
    دورية أكاديمية

    المصدر: ILMU KELAUTAN: Indonesian Journal of Marine Sciences; Vol 29, No 1 (2024): Ilmu Kelautan; 29-36 ; 2406-7598 ; 0853-7291

    الوصف: Sabah is the main seaweed producer in Malaysia especially red seaweeds which are commercially cultivated for the production of food gum known as carrageenan. Seaweeds are also high in phytochemical such as antioxidant compounds. Three seaweeds species from the Semporna Seawater, Sabah, namely Kappaphycus alvarezii, Caulerpa lentillifera and Sargassum polycystum were chosen for this study for the analysis of their antioxidant activities. K. alvarezii species is commercially cultivated whereas the other two (C. lentillifera and S. polycystum) are wild species. All seaweeds species underwent drying process in a cabinet dryer prior to the analyses. Six types of solvents which were water, ethanol, methanol, chloroform, ethyl acetate and hexane were used for the extraction process. Every concentrated, extracted solutions were then measured for their antioxidant activities based on total phenolic content (TPC), diphenylpicrylhydrazyl (DPPH) radical scavenging activity, ferric reducing antioxidant power (FRAP) and β-carotene bleaching assay. Results showed that TPC of S. polycystum was significantly higher (p<0.05) than K. alvarezii but not significantly different (P>0.05) from C. lentillifera. Even though the extraction yield of water was the highest, but the greatest antioxidant activity values were seen in methanolic extraction in comparison to the other solvents in TPC, DPPH and FRAP. This indicated that most of the antioxidant compounds in all the three seaweed samples are polar. However, high antioxidant activity in terms of β-carotene bleaching assay were seen in other solvent extractions, which were chloroform, hexane and ethyl acetate. This indicated that seaweed also contain non-polar antioxidant compounds such as β-carotene. Overall, the best extraction method of antioxidant compounds in seaweed samples was using methanol as the extractant.

    وصف الملف: application/pdf

  3. 3
    دورية أكاديمية

    المصدر: Bulletin of Culinary Art and Hospitality; Vol. 3 No. 2 (2023); 66-71 ; 2797-8249

    مصطلحات موضوعية: Proximate, Dewandaru fruit, Dried sweets

    الوصف: Dried sweet fruit is a diversified food product that is popular in Indonesia. Dewandaru fruit (Eugenia uniflora L.) dried sweets are expected to be a preferred and beneficial product for health. This study aimed to analyze the Proximate content of Dewandaru fruit. This experimental study utilized a Completely Randomized Design (CRD) with four different drying time treatments consisting of 4 levels (6 hours, 7 hours, 8 hours, and 9 hours) and 2 replications. Observation data were analyzed using One-way ANOVA followed by the DMRT test. The results showed that Dewandaru dried sweets with a drying time of nine hours had the highest chemical properties based on the parameters of the protein content of 3.56 percent, moisture content of 30.90 percent, ash content of 1.81 percent, carbohydrate content of 63.96 percent, fat content 0.4 percent, flavonoids 5,950.85 mg/kg, saponins 46.70 mg/kg, and tannins 242.56 mg/kg. Thus, the drying time rate affects the chemical properties of Dewandaru fruit. However, drying for 9 hours has a higher fat content than other treatments.

    وصف الملف: application/pdf

    العلاقة: //bocahjournal.um.ac.id/index.php/bocah/article/view/45/30; //bocahjournal.um.ac.id/index.php/bocah/article/view/45

  4. 4
    دورية أكاديمية
  5. 5
    دورية أكاديمية

    المصدر: Biology, Medicine & Natural Product Chemistry, Vol 11, Iss 1, Pp 55-63 (2022)

    الوصف: Cervical cancer is the second most common type of malignant tumor found in women aged 15-44 years worldwide. Radiotherapy is one form of treatment that uses radiation that can eliminate or kill cancer cells and one way to treat cervical cancer is quite popular. Chemotherapy is a cancer treatment using anticancer drugs designed to kill or slow the growth of cancer cells that divide rapidly in the body. The method used is to study mathematical model of cervical cancer with radiotherapy and radiotherapy treatment followed by chemotherapy. The results of this study are for the early stages of cervical cancer with radiotherapy is quite effective, while for the late stages of radiotherapy and chemotherapy is less effective. Therefore, the need for other treatments for end-stage cervical cancer in addition to radiotherapy and chemotherapy.

    وصف الملف: electronic resource

  6. 6
    دورية أكاديمية

    المصدر: Anjoro: International Journal of Agriculture and Business; Vol 4 No 1 (2023): Anjoro; 1-9 ; 2721-7914 ; 2721-8678 ; 10.31605/anjoro.v4i1

    الوصف: Brassica oleracea L. italica, the scientific name for broccoli, is a vegetable that is frequently consumed for its florets, which have a number of health benefits. However, other portions of the plant, including the leaves, are almost always discarded despite being good for human health. The study was carried out with the purpose of investigating how the physicochemical characteristics of powdered broccoli leaves were affected by blanching and various drying techniques applied. Broccoli leaves were first blanched in hot water before being dried, which included sun drying, oven drying, cabinet drying, and vacuum drying. The findings demonstrated that blanching enhanced the powder's physical attributes while maintaining its phenolic and flavonoid contents. Blanching also reduced the breakdown of the chlorophyll content in all drying techniques, although this process made it harder to keep the goods' antioxidant function. In conclusion, vacuum drying method of blanched broccoli leaf powder showed the highest retention of physicochemical properties, phytochemical content, and antioxidant activity.

    وصف الملف: application/pdf

  7. 7
    دورية أكاديمية

    المساهمون: Universiti Malaysia Sabah, RH Serunding, Serunding Kobis Sabah, Serunding Kubis Kundasang, Serunding Kubis Kak Ida, Serunding Kubis Umi Irsa, Ice cool bakery, Jabatan Pertanian

    المصدر: BASKARA : Journal of Business and Entrepreneurship; Vol 5, No 2 (2023): BASKARA: Journal of Business and Entrepreneurship; 232-244 ; 2623-0089

    الوصف: The management of agricultural resources is an important agenda especially during the period of COVID-19 pandemic, which has increased food waste from agricultural products and the loss of sources of income among communities involved in agricultural activities. However, food waste remains as an urgent matter even in post-COVID-19 pandemic. This article aims to discuss about how local knowledge is used to deal with the agriculture waste. Vegetables dumping issues causing waste and affecting the income of farmers and vegetable sellers. Therefore, innovations in processing vegetables into processed food was implemented to optimize agribussines values. In achieving this goal, the steps to be taken are to empower the existing knowledge so called ‘local knowledge’. The information in producing this article was gathered through observation of community who participate voluntarily and interviews with Department of Agriculture, Federal Agricultural Marketing Authority (FAMA) and The Ministry of Agriculture and Food Industries and abbreviated (MAFI). The results of the study found that the main methods of food processing method by the community are preserving, drying, smoking or curing and frying. Hence this these methods were used to process cabbage (Brassica oleracea) into several products namely (1) cabbage floss, (2) salted cabbage, (4) cabbage bosou and (4) cabbage kimchi.

    وصف الملف: application/pdf

  8. 8
    دورية أكاديمية

    المصدر: Bulletin of Culinary Art and Hospitality; Vol. 3 No. 1 (2023); 5-12 ; 2797-8249

    الوصف: Using Okara flour, this study evaluates its effect on the quality of soda crackers. Nine formulations were produced; namely, the cracker with 15, 20, and 25 percent okara flour was developed with 8, 10, and 12 percent margarine, respectively. Four formulations were chosen using the BIB test on the mean score. The best okara cracker was identified through a hedonic test by trained panelists based on the attributes of color, aroma, taste, texture, crispness, and overall acceptance. Proximate analysis was conducted on the best formulation showing that the best recipe consisted of 6.44 percent moisture, 12.96 percent protein, 8.65 percent fat, 2.41 percent ash, 2.35 percent crude fiber, 67.30 percent carbohydrate, 14.62 percent dietary fiber, and 428.12 kcal/g energy content. The color of the best formulation was significantly (p less than 0.05) darker than the control sample due to its high protein content. Therefore, the rate of Millard reaction had increased compared to the control sample. Additionally, the hardness and fracturability of the okara cracker were found to be significantly (p less than 0.05) higher than the control sample, mainly due to the high protein content in the cracker. The stack height decreased as okara content increased high water absorption and weak gluten formation. Hence, it could be claimed as a product with high dietary fiber and a source of protein.

    وصف الملف: application/pdf

    العلاقة: //bocahjournal.um.ac.id/index.php/bocah/article/view/35/22; //bocahjournal.um.ac.id/index.php/bocah/article/view/35

  9. 9
    دورية أكاديمية

    المساهمون: No fund received during the study period

    المصدر: Arabian Journal of Medicinal and Aromatic Plants; Vol. 9, No 2 (2023); 151-166 ; 2458-5920

    الوصف: Thymus laevigatus Vahl (Lamiaceae) is an endemic subshrub plant with a herbaceous shape that grows wild in higher mountainous regions in the Northern part of Yemen. Its aerial parts are used locally as an appetizer and in folk medicine. It is used to treat cough and pharyngitis. The identity, conservation, usage and geographical distribution of this species, unlike most other species in the Thymus genus, has not received extensive studies. This study aimed to determine detailed morphological features of T. laevigatus grown in Yemen, to facilitate differentiation and identification of its medicinal raw parts. Fresh specimens from five different natural populations grown in five different locations were morphologically studied. Fresh specimens of the whole plant, stem, leaf, inflorescence and flower parts were compared. Results showed that T. laevigatus is a perennial and subshrub with a herbaceous shape. The stem is repent, monopodial plagiotropic growth and pubescence on all four faces. The leaf is simple with an entire margin. Blade shape differs clearly between specimens collected from different locations. It was observed to be either oblanceolate or oblance-ovate. The inflorescence is capitate type. Bracts are similar to upper leaves in shape, but smaller in size. However, the bracts are distinguished by the presence of tall multicellular trichomes in the lower two-thirds of their blade's edges. The calyx is tubular-campanulate, while the corolla is a campanula-tubular with hairy tube. Corolla's color is either white or pale pink. The results obtained can be used for the development of herbal medicinal plants' regulatory documents in Yemen.

    وصف الملف: application/pdf

  10. 10
    دورية أكاديمية

    المصدر: BMC Pediatrics ; volume 23, issue 1 ; ISSN 1471-2431

    مصطلحات موضوعية: Pediatrics, Perinatology and Child Health

    الوصف: Background Vitamin D is one of the most important fat-soluble vitamins necessary for normal growth and development of the human body. According to a study done in Kabul shows that economic, racial, and social concerns are thought to be the main impediments to receiving appropriate amounts of this vitamin through dietary sources in countries like Afghanistan. Hypovitaminosis D, on the other hand, is now recognized as a pandemic in both industrialized and developing countries. Methods To find out how common hypovitaminosis D is in children aged one month to eighteen years in afghan children Kabul, Afghanistan. Vitamin D deficiency and insufficiency are defined as serum levels of less than 20 ng/mL and 20 to 30 ng/mL, respectively. Children aged between 1 month to 18 years attending our hospital, AMC (Ariana Medical Complex) for health examination were checked for their 25-hydroxyvitamin D [25(OH)D]. Age, gender and address were recorded. 25(OH)D were determined using immunoassay auto analyzers. According to their serum 25(OH)D, the 25(OH)D were categorized into five categories: sufficiency: ≥ 30-100 ng/mL; insufficiency: ≥ 20-29 ng/mL; deficiency: < 20 ng/mL; severe deficiency: < 10 ng/mL; and intoxication: > 150 ng/mL. Participants who were intoxicated with vitamin D were excluded from the study. Results A total of 4008 children aged 1 month to 18 years participated in this cross-sectional study. Hypovitaminosis D was found to be prevalent in 62.5 percent of the population. When compared to boys, female children were 1.2 times more likely to be vitamin D deficient. When compared to children of illiterate women, the odds of hypovitaminosis D were 1.4, 1.9, and 5.8 times lower in children with mothers educated up to primary school, graduation, and post-graduate. The average vitamin D level was 23 ng/mL, with a median of 15 ng/mL and maximum and minimum values of 135 ng/mL and 3 ng/mL, respectively. In all, 2500 (62.5%) of the children had low levels of vitamin D in their serum. Only 400 (16%) of ...