المؤلفون: Mannarathu Devasia MATHEW, Sardari Lal MANNAN, Subash Chandra CHETAL, Tammana JAYAKUMAR

المصدر: Journal of Solid Mechanics and Materials Engineering. 2013, 7(4):473

المؤلفون: de Menil Victoria, Wood Sarah K, Raja Shoba, Mannarath Saju C

المصدر: International Journal of Mental Health Systems, Vol 4, Iss 1, p 11 (2010)

مصطلحات موضوعية: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

الوصف: Abstract Background Limited evidence about mental health finances in low and middle-income countries is a key challenge to mental health care policy initiatives. This study aimed to map mental health finances in Ghana, Uganda, India (Kerala state), Sri Lanka and Lao PDR focusing on how much money is available for mental health, how it is spent, and how this impacts mental health services. Methods A researcher in each region reviewed public mental health-related budgets and interviewed key informants on government mental health financing. A total of 43 key informant interviews were conducted. Quantitative data was analyzed in an excel matrix using descriptive statistics. Key informant interviews were coded a priori against research questions. Results National ring-fenced budgets for mental health as a percentage of national health spending for 2007-08 is 1.7% in Sri Lanka, 3.7% in Ghana, 2.0% in Kerala (India) and 6.6% in Uganda. Budgets were not available in Lao PDR. The majority of ring-fenced budgets (76% to 100%) is spent on psychiatric hospitals. Mental health spending could not be tracked beyond the psychiatric hospital level due to limited information at the health centre and community levels. Conclusions Mental health budget information should be tracked and made publically accessible. Governments can adapt WHO AIMS indicators for reviewing national mental health finances. Funding allocations work more effectively through decentralization. Mental health financing should reflect new ideas emerging from community based practice in LMICs.

وصف الملف: electronic resource

العلاقة: http://www.ijmhs.com/content/4/1/11Test; https://doaj.org/toc/1752-4458Test

الوصول الحر: https://doaj.org/article/773e4c7893e345c39c4ad60a8606962fTest

المؤلفون: Jon Landa, Ana Beatriz Serafim, Mercedes Alba, Estibaliz Maudes, Laura Molina-Porcel, Anna Garcia-Serra, Francesco Mannara, Josep Dalmau, Francesc Graus, Lidia Sabater

المصدر: Frontiers in Immunology, Vol 15 (2024)

مصطلحات موضوعية: Iglon5, animal model, knockout, behavior (mice), anti-IgLON5 antibody encephalopathy, Immunologic diseases. Allergy, RC581-607

الوصف: BackgroundAnti-IgLON5 disease is a neurological disorder characterized by autoantibodies against IgLON5 and pathological evidence of neurodegeneration. IgLON5 is a cell adhesion molecule of unknown function that is highly expressed in the brain. Our aim was to investigate the impact of IgLON5 loss-of-function in evaluating brain morphology, social behavior, and the development of symptoms observed in an IgLON5 knockout (IgLON5-KO) mouse model.MethodsThe IgLON5-KO mice were generated using CRISPR-Cas9 technology. Immunohistochemistry on fixed sagittal brain sections and Western blotting brain lysates were used to confirm IgLON5 silencing and to evaluate the presence of other cell surface proteins. Two- month-old IgLON5-KO and wild-type (WT) mice underwent a comprehensive battery of behavioral tests to assess 1) locomotion, 2) memory, 3) anxiety, 4) social interaction, and 5) depressive-like behavior. Brain sections were examined for the presence of anatomical abnormalities and deposits of hyperphosphorylated tau in young adult (2-month-old) and aged (22-month-old) mice.ResultsMice did not develop neurological symptoms reminiscent of those seen in patients with anti-IgLON5 disease. Behavioral testing revealed that 2-month-old IgLON5-KO mice showed subtle alterations in motor coordination and balance. IgLON5-KO females exhibited hyperactivity during night and day. Males were observed to have depressive-like behavior and excessive nest-building behavior. Neuropathological studies did not reveal brain morphological alterations or hyperphosphorylated tau deposits.ConclusionIgLON5-KO mice showed subtle alterations in behavior and deficits in fine motor coordination but did not develop the clinical phenotype of anti-IgLON5 disease.

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1347948/fullTest; https://doaj.org/toc/1664-3224Test

الوصول الحر: https://doaj.org/article/52aef26154374e02aaa295b0228c01faTest

المؤلفون: Landa, Jon, Serafim, Ana Beatriz, Alba, Mercedes, Maudes, Estibaliz, Molina-Porcel, Laura, Garcia-Serra, Anna, Mannara, Francesco, Dalmau, Josep, Graus, Francesc, Sabater, Lidia

المساهمون: Instituto de Salud Carlos III

المصدر: Frontiers in Immunology ; volume 15 ; ISSN 1664-3224

مصطلحات موضوعية: Immunology, Immunology and Allergy

الوصف: Background Anti-IgLON5 disease is a neurological disorder characterized by autoantibodies against IgLON5 and pathological evidence of neurodegeneration. IgLON5 is a cell adhesion molecule of unknown function that is highly expressed in the brain. Our aim was to investigate the impact of IgLON5 loss-of-function in evaluating brain morphology, social behavior, and the development of symptoms observed in an IgLON5 knockout (IgLON5-KO) mouse model. Methods The IgLON5-KO mice were generated using CRISPR-Cas9 technology. Immunohistochemistry on fixed sagittal brain sections and Western blotting brain lysates were used to confirm IgLON5 silencing and to evaluate the presence of other cell surface proteins. Two- month-old IgLON5-KO and wild-type (WT) mice underwent a comprehensive battery of behavioral tests to assess 1) locomotion, 2) memory, 3) anxiety, 4) social interaction, and 5) depressive-like behavior. Brain sections were examined for the presence of anatomical abnormalities and deposits of hyperphosphorylated tau in young adult (2-month-old) and aged (22-month-old) mice. Results Mice did not develop neurological symptoms reminiscent of those seen in patients with anti-IgLON5 disease. Behavioral testing revealed that 2-month-old IgLON5-KO mice showed subtle alterations in motor coordination and balance. IgLON5-KO females exhibited hyperactivity during night and day. Males were observed to have depressive-like behavior and excessive nest-building behavior. Neuropathological studies did not reveal brain morphological alterations or hyperphosphorylated tau deposits. Conclusion IgLON5-KO mice showed subtle alterations in behavior and deficits in fine motor coordination but did not develop the clinical phenotype of anti-IgLON5 disease.

الإتاحة: https://doi.org/10.3389/fimmu.2024.1347948Test

المؤلفون: Coppola, Lucia, Reder, Alfredo, Tarantino, Alessandro, Mannara, Giovanni, Pagano, Luca

المصدر: E3S Web of Conferences; 7/4/2024, Vol. 544, p1-8, 8p

المؤلفون: Córdoba-Jover, Bernat, Ribera, Jordi, Portolés, Irene, Lecue, Elena, Rodriguez-Vita, Juan, Pérez-Sisqués, Leticia, Mannara, Francesco, Solsona-Vilarrasa, Estel, Garcia-Ruiz, Carmen, Fernández-Checa, José C., Casals, Gregori, Rodríguez-Revenga, Laia, Álvarez-Mora, María Isabel, Arteche-López, Ana, Díaz de Bustamante, Aranzazu, Calvo, Rosa, Pujol, Anna, Azkargorta, Mikel, Elortza, Felix, Malagelada, Cristina, Pinyol, Roser, Huguet-Pradell, Júlia, Melgar-Lesmes, Pedro, Jiménez, Wladimiro, Morales-Ruiz, Manuel

المساهمون: Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), Ministerio de Ciencia e Innovación (España), Ministerio de Economía y Competitividad (España), Generalitat de Catalunya, Fundación Mutua Madrileña, European Commission, Fundació La Marató de TV3, Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (España), Jiménez, Wladimiro, Morales-Ruiz, Manuel

مصطلحات موضوعية: TCF20, Collagen, Liver fibrosis, Metabolic disease, Newborn lethality, Succinate

الوصف: Transcription co-activator factor 20 (TCF20) is a regulator of transcription factors involved in extracellular matrix remodelling. In addition, TCF20 genomic variants in humans have been associated with impaired intellectual disability. Therefore, we hypothesized that TCF20 has several functions beyond those described in neurogenesis, including the regulation of fibrogenesis. ; We acknowledge the support from grants PDI2019-105502RB-100 and PID2022-138243OB-I00 to MM-R, PID2019-111669RB, BES-2017-080823 to IP "ESF Investing in your future", and RTI2018-094734-B-C21 to WJ and PM-L, from MCIN/AEI/10.13039/501100011033. RedFibro (RED2022-134485-T) of the 2022 caLL for aid to «RESEARCH NETWORKS», within the framework of the Programa Estatal del Plan Estatal de Investigación Científica, Técnica y de Innovación 2021–2023. Consolidated Research Group of the Generalitat de Catalunya AGAUR (2021 SGR 00881 to MM-R) and PM-L financed ESF Investing in your future, support from AGAUR of the Generalitat de Catalunya. Fundación Mutua Madrileña AP171442019, European Cooperation in Science & Technology (COST) ACTION CA17112 Prospective European Drug-Induced Liver Injury Network, and the Project 201 916/31 Contribution of mitochondrialoxysterol and bile acid metabolism to liver carcinogenesis 2019 by Fundació Marató TV3. PM-L was additionally supported by a fellowship from the Ramon y Cajal Program (RYC2018-0Z23971-I) and a grant (PID2021-123426OB-I00) from the Spanish Ministerio de Ciencia, Innovación y Universidades. CIBERehd is financed by the Instituto de Salud Carlos III. ; Peer reviewed

وصف الملف: application/pdf

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-105502RB-I00/ES/NUEVOS MECANISMOS MOLECULARES Y NUEVAS ESTRATEGIAS TERAPEUTICAS APLICABLES A LA CONSERVACION DE LA FUNCION HEPATICA Y A LA MEJORA DE LA ENFERMEDAD HEPATICA CRONICA/; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-138243OB-I00/ES/FUNCION Y POTENCIAL TERAPEUTICO DE LAS HELICASAS DE RNA Y DE MIR-122A-5P EN LA REGENERACION HEPATICA Y EL CANCER/; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-111669RB-I00/ES/STARD1 Y SAB EN LA ENFERMEDAD ALCOHOLICA HUMANA: VALIDACION EN UN MODELO MURINO CON HIGADO HUMANIZADO/; info:eu-repo/grantAgreement/MINECO//SAF2016-75358-R; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-094734-B-C21/ES/UTILIDAD TERAPEUTICA Y DE NUEVOS TRATAMIENTOS PARA LAS ENFERMEDADES HEPATICAS: RNA DE INTERFERENCIA PARA PTTG1, NANOPARTICULAS DE CARBONO GRAFITO Y DONADORES DE OXIDO NITRICO/; info:eu-repo/grantAgreement/AEI//RED2022-134485-T; info:eu-repo/grantAgreement/AEI//RYC2018-0Z23971-I; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2021-123426OB-I00/ES/NUEVAS ESTRATEGIAS TERAPEUTICAS INMUNOMODULADORAS PARA LAS ENFERMEDADES HEPATICAS: MATRICES CON CELULAS ENDOTELIALES Y NANOPARTICULAS DENDRIMERICAS DIRIGIDAS A MACROFAGO/; Publisher's version; The underlying dataset has been published as supplementary material of the article in the publisher platform at https://doi.org/10.1111/liv.15640Test; https://doi.org/10.1111/liv.15640Test; Sí; Liver International 43(8): 1822-1836 (2023); http://hdl.handle.net/10261/348763Test; http://dx.doi.org/10.13039/501100003329Test; http://dx.doi.org/10.13039/100008666Test; http://dx.doi.org/10.13039/100008061Test; http://dx.doi.org/10.13039/501100002809Test; http://dx.doi.org/10.13039/501100004587Test; http://dx.doi.org/10.13039/501100004837Test; http://dx.doi.org/10.13039/501100011033Test; http://dx.doi.org/10.13039/501100000780Test; 2-s2.0-85163139135; https://api.elsevier.com/content/abstract/scopus_id/85163139135Test

الإتاحة: https://doi.org/10.1111/liv.1564010.13039/50110000332910.13039/10000866610.13039/10000806110.13039/50110000280910.13039/50110000458710.13039/50110000483710.13039/50110001103310.13039/501100000780Test
http://hdl.handle.net/10261/348763Test
https://api.elsevier.com/content/abstract/scopus_id/85163139135Test

المؤلفون: Coppola, L., Reder, A., Tarantino, A., Mannara, G., Pagano, L.

مصطلحات موضوعية: Geology, Environmental engineering

الوصف: The majority of the Landslide Early Warning Systems (LEWS) currently in operation are based on the monitoring of rainfall data alone and this limits their performance due to false alarms generated by rainfall thresholds that are inevitably set conservative. The accuracy of LEWS may be significantly enhanced by monitoring soil-based variables associated with the stress-strain response of the ground. This paper investigates whether slope pre-failure deformation can be used as additional precursor of landslide initiation. This would lead to a substantial improvement of LEWS accuracy especially if pre-failure deformation is combined with suction monitoring. Tests were carried out using a small-scale physical model of a slope built with unsaturated volcanic silt subjected to artificial rainfall. A new device named tensio-inclinometer was purposely developed to monitor simultaneously suction and suction-induced deformation. It combines a conventional tensiometer and an accelerometer installed at the top of the tensiometer shaft. It is shown that pre-failure deformation detected by the tilting of the tensiometer shaft is an adequate landslide precursor and that, combined with suction, can provide soil-based thresholds for early warning systems.

وصف الملف: text

العلاقة: https://strathprints.strath.ac.uk/82151/1/Coppola_etal_EG_2022_Pre_failure_suction_induced_deformation_to_inform_early_warning_of_shallow_landslides.pdfTest; Coppola, L. and Reder, A. and Tarantino, A. and Mannara, G. and Pagano, L. (2022 ) Pre-failure suction-induced deformation to inform early warning of shallow landslides : proof of concept at slope model scale. Engineering Geology , 309. 106834. ISSN 0013-7952

الإتاحة: https://doi.org/10.1016/j.enggeo.2022.106834Test
https://strathprints.strath.ac.uk/82151Test/
https://strathprints.strath.ac.uk/82151/1/Coppola_etal_EG_2022_Pre_failure_suction_induced_deformation_to_inform_early_warning_of_shallow_landslides.pdfTest

المؤلفون: Kweh, Barry Ting Sheen, Tee, Jin Wee, Muijs, Sander, Oner, F. Cumhur, Schnake, Klaus John, Benneker, Lorin Michael, Vialle, Emiliano Neves, Kanziora, Frank, Rajasekaran, Shanmuganathan, Schroeder, Gregory, Vaccaro, Alexander R., Grin, Andrey, Abdelgawaad, Ahmed Shawky, Zubairi, Akbar Jaleel, Castillo, Alejandro, Lezica, Alejo Vernengo, Ramieri, Alessandro, Guiroy, Alfredo, Grundshtein, Alon, Godinho, Amauri, Henine, Amin, Pershin, Andrei A., Athanasiou, Alkinoos, Zarate-Kalfopulos, Baron, Benzarti, Sofien, Bernucci, Claudio, Rebholz, Brandon J., Direito-Santos, Bruno, Costa, Bruno Lourenço, Saciloto, Bruno, Majer, Catalin, Tannoury, Chadi, Cheng, Christina, Cheung, Jason Pui Yin, Konrads, Christian, Jetjumnong, Chumpon, Chung, Chun Kee, Popescu, Eugen Cezar, Kilinçer, Cumhur, Harrism, Colin B., Steiner, Craig D., Igualada, Cristina, Perovic, Darko, Picazo, David Ruiz, Falcone, Luis David Orosco, Gopalakrishnan, Dilip, Ankit, Desai, Tokala, Devi Prakash, Karmacharya, Balgopal, Lotan, Raphael, Shoaib, Mahmoud, Russo, Salvatore, Viswanadha, Arun Kumar, Garg, Bhavuk, Uribe, Noe Dimas, Medina, Fabricio, Subbiah, Jayakumar, Alsammak, Wael, Mandizvidza, Valentine, Atan, Ahmad Arieff, Barani, Rathinavelu, Sámano, Hugo Vilchis, Pemovska, Emilija Stojkovska, Hinojosa, Fabian Catarino Lopez, Fang, Taolin, Landriel, Federico, Sartor, Federico Daniel, De Oliveira Ferreira, Marcus Vinicius, Fiorenza, Vito, Mannara, Francisco Alberto, Franz, Seibert, Freedman, Brett A., Grozman, Samuel Arsenio M., Espinosa, Guillermo, Ricciardi, Guillermo Alejandro, Ponnusamy, Gunaseelan, Amadou, Hassane Ali, Romero, Itati, Rutges, Joost, Harrop, James, Sauri-Barraza, Jose-Carlos, Sharma, Jeevan Kumar, Arbatin, Jose Joefrey F., Milano, Jeronimo B., Francis, Jibin Joseph, Li Tat, John Chen, Vahl, Joachim, Corredor, Jose Alfredo, Morais, João Moreno, Guasque, Joana, Koerner, John, Johnny, Duerinck, Ron, Jose Rafael Perozo, Delgado-Fernandez, Juan, Montoya, Juan Esteban Muñoz, Lourido, Juan, Kaen, Ariel, Özdener, Kubilay Murat, Margetis, Konstantinos, Paterakis, Konstantinos, Cari, Lady Lozano, Fu, Lingjie, Dawoud, Ahmed, Luna, Luis Muñiz, Alkharsawi, Mahmoud, Diez-Ulloa, Maximo-Alberto, García-Pallero, Maria A., Pluderi, Mauro, Gruenberg, Marcelo, Valacco, Marcelo, Ganau, Mario, Estefan, Martin M., Rodríguez, Luis Miguel Duchén, Miyakoshi, Naohisa, Elshamly, Mahmoud, Khattab, Mohamed Fawzy, Smith, Sean R., Abeid, Mbarak, Garfinkel, Ignacio, Nicassio, Nicola, Neves, Nuno, Acosta, Olga Carolina Morillo, Bazán, Pedro Luis, Pereira, Paulo, Lim, Phedy, Pritchard, Patrick R., Bhatt, Pragnesh, Kundangar, Raghuraj, Vieira, Rian Souza, Rodrigues-Pinto, Ricardo, Panchal, Ripul R., Llombart-Blanco, Rafael, Rosas, Ronald Alberto Rioja, Manilha, Rui, Yurac, Ratko, Diniz, Sara, Wagner, Scott C., Fuego, Segundo, Ramakrishnan, Selvaraj, Demiröz, Serdar, Hackla, Shafiq, Shariati, Babak, El-Sharkawi, Mohammad, Sorimachi, Yasunori, Corluka, Stipe, Yuh, Sung-Joo, Benzakour, Thami, ElHewala, Tarek, Suri, Tarun, Cawley, Derek T., Toluse, Adetunji, Valdez, Cristian, Abdul, Waheed, Hassan, Waqar, Robinson, Yohan, Hickman, Zachary L., Amin, Mohamad Zaki Haji Mohd, Guerra, Oscar González, Klezl, Zdenek

المساهمون: Chung, Chun Kee

الوصف: © 2022 The authors.OBJECTIVE Optimal management of A3 and A4 cervical spine fractures, as defined by the AO Spine Subaxial Injury Classification System, remains controversial. The objectives of this study were to determine whether significant management variations exist with respect to 1) fracture location across the upper, middle, and lower subaxial cervical spine and 2) geographic region, experience, or specialty. METHODS A survey was internationally distributed to 272 AO Spine members across six geographic regions (North America, South America, Europe, Africa, Asia, and the Middle East). Participants management of A3 and A4 subaxial cervical fractures across cervical regions was assessed in four clinical scenarios. Key characteristics considered in the vignettes included degree of neurological deficit, pain severity, cervical spine stability, presence of comorbidities, and fitness for surgery. Respondents were also directly asked about their preferences for operative management and misalignment acceptance across the subaxial cervical spine. RESULTS In total, 155 (57.0%) participants completed the survey. Pooled analysis demonstrated that surgeons were more likely to offer operative intervention for both A3 (p < 0.001) and A4 (p < 0.001) fractures located at the cervicothoracic junction compared with fractures at the upper or middle subaxial cervical regions. There were no significant variations in management for junctional incomplete (p = 0.116) or complete (p = 0.342) burst fractures between geographic regions. Surgeons with more than 10 years of experience were more likely to operatively manage A3 (p < 0.001) and A4 (p < 0.001) fractures than their younger counterparts. Neurosurgeons were more likely to offer surgical stabilization of A3 (p < 0.001) and A4 (p < 0.001) fractures than their orthopedic colleagues. Clinicians from both specialties agreed regarding their preference for fixation of lower junctional A3 (p = 0.866) and A4 (p = 0.368) fractures. Overall, surgical fixation was ...

العلاقة: Journal of Neurosurgery: Spine, Vol.36 No.1, pp.99-112; https://hdl.handle.net/10371/183921Test; 000744151700005; 2-s2.0-85124916122; 160822

الإتاحة: https://doi.org/10.3171/2021.3.SPINE201997Test
https://hdl.handle.net/10371/183921Test

المؤلفون: Karamian, Brian A., Schroeder, Gregory D., Lambrechts, Mark J., Canseco, Jose A., Oner, Cumhur, Vialle, Emiliano, Rajasekaran, Shanmuganathan, Dvorak, Marcel R., Benneker, Lorin M., Kandziora, Frank, Schnake, Klaus, Kepler, Christopher K., Vaccaro, Alexander R., Costa, Bruno Lourenco, Estefan, Martin, Dawoud, Ahmed, Kaen, Ariel, Yuh, Sung-Joo, Fuego, Segundo, Mannara, Francisco, Ponnusamy, Gunaseelan, Suri, Tarun, Jayakumar, Subiiah, Rodriguez, Luis Cuchen, Cawley, Derek, Godinho, Amauri, Duerinck, Johnny, Montemurro, Nicola, Ozdener, Kubilay, Hickman, Zachary, Wael, Alsammak, Gopalakrishnan, Dilip, Santos, Bruno, Morillo, Olga, Sorimachi, Yasunori, Miyakoshi, Naohisa, Alkharsawi, Mahmoud, Rahamimov, Nimrod, Loya, Vijay, Loughenbury, Peter, Rodrigues, Jose, Ankur, Nanda, Alarcon, Olger, Ampar, Nishanth, Sprengel, Kai, Subramaniam, Macherla, Linn, Kyaw, Subramanian, Panchu, Osterhoff, Georg, Mlyavykh, Sergey

المصدر: European Spine Journal ; volume 32, issue 1, page 46-54 ; ISSN 0940-6719 1432-0932

مصطلحات موضوعية: Orthopedics and Sports Medicine, Surgery

الوصف: Purpose To validate the AO Spine Subaxial Injury Classification System with participants of various experience levels, subspecialties, and geographic regions. Methods A live webinar was organized in 2020 for validation of the AO Spine Subaxial Injury Classification System. The validation consisted of 41 unique subaxial cervical spine injuries with associated computed tomography scans and key images. Intraobserver reproducibility and interobserver reliability of the AO Spine Subaxial Injury Classification System were calculated for injury morphology, injury subtype, and facet injury. The reliability and reproducibility of the classification system were categorized as slight ( ƙ = 0–0.20), fair ( ƙ = 0.21–0.40), moderate ( ƙ = 0.41–0.60), substantial ( ƙ = 0.61–0.80), or excellent ( ƙ = > 0.80) as determined by the Landis and Koch classification. Results A total of 203 AO Spine members participated in the AO Spine Subaxial Injury Classification System validation. The percent of participants accurately classifying each injury was over 90% for fracture morphology and fracture subtype on both assessments. The interobserver reliability for fracture morphology was excellent ( ƙ = 0.87), while fracture subtype ( ƙ = 0.80) and facet injury were substantial ( ƙ = 0.74). The intraobserver reproducibility for fracture morphology and subtype were excellent ( ƙ = 0.85, 0.88, respectively), while reproducibility for facet injuries was substantial ( ƙ = 0.76). Conclusion The AO Spine Subaxial Injury Classification System demonstrated excellent interobserver reliability and intraobserver reproducibility for fracture morphology, substantial reliability and reproducibility for facet injuries, and excellent reproducibility with substantial reliability for injury subtype.

الإتاحة: https://doi.org/10.1007/s00586-022-07467-6Test

المؤلفون: Radosevic, Marija, Planagumà, Jesús, Mannara, Francesco, Mellado, Araceli, Aguilar, Esther, Sabater, Lidia, Landa, Jon, García-Serra, Anna, Maudes, Estibaliz, Gasull, Xavier, Lewis, Mike, Dalmau, Josep

المصدر: Neurology Neuroimmunology & Neuroinflammation ; volume 9, issue 1 ; ISSN 2332-7812

الإتاحة: https://doi.org/10.1212/nxi.0000000000001122Test