المؤلفون: Mader R., Demay C., Jouvin-Marche E., Ploy M. -C., Barraud O., Bernard S., Lacotte Y., Pulcini C., Weinbach J., Berling C., Bouqueau M., Hlava A., Habl C., Kernstock E., Strauss R., Muchl R., Buhmann V., Versporten A., Ingenbleek A., Vandael E., Haelterman G., De Raedt L., Hunjak B., Raickovic B., Mackova B., Niklova E., Zemlickova H., Hrivnakova L., Jindrak V., Kristensen B., Lyndrup M., Skovgaard S., Wolf Sonksen U., Aasmae B., Ruut J., Linnik L., Sadikova O., Martin P., Zanuzdana A., Kizilkaya-Guneser G., Oezcelik N., Eckmanns T., Lambrou A., Kontopidou F., Papadaki M., Tsana M., Maroulis N., Vatopoulos A., Papadogiannakis E., Kontarini M., Gikas A., Magkanaraki A., Cozza A., Martinelli D., Fortunato F., Prato R., Marella A. M., Pantosti A., Prestinaci F., Busani L., Pezzoti P., Creti R., Martoccia R. M., Brusaferro S., Vilde A., Jakovela A., Langusa E., Grudule L., Grinsteine M., Dumpis U., Dambrauskiene A., Vitkauskiene A., Tirvaite D., Cemnalianskis L., Kazenaite E., Lozoraitiene I., Adomaitiene R., Ambrazaitiene R., Kiveryte S., Maciulaityte A., Kuklyte J., Petrene J., Valinteliene R., Kanapeckiene V., Razmiene A., Kairiene B., Aleksiene G., Valinciute G., Petraitis R., Elsemulder A., Nakched A., Claessen J., Gui L., Kort M. D., Peran R., Van Leeuwen A., Smeets E., Mennen M., Spruijt P., Westerhof R., Skulberg A., Bakka E. Ro., Miard K., Henricsen S. Ho., Pellerud A., Kallberg C., Ardal C., Eriksen H. -M., Kranstad K., Molvik M., Kacelnik O., Sollund P., Samuelsen R., Bakke T., Urdahl A. M., Norstrom M., Olczak-Pienkowska A., Skoczynska A., Zabicka D., Bysiek J., Rekawek J., Lebre A., Falcao E., Scripcaru G., Neves I., Gomes S., Pereira N., Malutan A. M., Iuhas C., Szakacs L., Kissiedou-Bob M., Ciortea R., Grilc E., Klavs I., Turk K., Subelj M., Vrdelja M., Serdt M., Jemec N., Glavan U., Simonovic Z., Tamayo A. N., Lopez Navas A., Munoz Madero C., Alonso Lebrero J. L., Alonso Irujo L., Santacreu Garcia M., Crespo Robledo P., Oliva G., Massanes M., Oliver Palomo A., Garcia Pineda A., Ferragut E., Rojo E., Castano E., Perianez L., Torres Cantero A. M., Jimenez Guillen C., Hukelova H., Alcaraz M., Carlos M. A., Lopez Acuna M. D. P., Gil Setas A., Ibarrola Segura A., Ezpeleta C., Gahigiro Merino C., Portillo Bordonabe M. E., Fragoso M., Beristain Rementeria X., Penalva G., Cisneros J. M., Estevez M., Monteau S., Del Rio L., Gonzalez De Suso M. J., Gallego Berciano P., Aranguren Oyarzabal A., Alioto D., Izquierdo Palomares J. M., Calvo Alcantara M. J., Gonzalez Perez R., Havarria T., Hulth A., Carlin K., Edman L., Grape M., Aspevall O., Haggar A., Lindal E., Burgos A., Ottoson J., Ostman M., Egervarn M., Nordenfelt A., Bengtsson B., Soderman I., Bjers A., Jonsson J. -I., Starborg M., Laine M., Fagerstedt P., Metcalfe A., Soder J., Lytsy B., Madec J. Y., Collineau L., Berger-Carbonne A., Colomb-Cotinat M., Bourely C., Amat J. -P., Broens E. M., Callens B., Crespo-Robledo P., Damborg P., Filippitzi M. -E., Fitzgerald W., Gronthal T., Haenni M., Heuvelink A., Van Hout J., Kaspar H., Pedersen K., Pokludova L., Dal Pozzo F., Slowey R., Zafeiridis C., Madec J. -Y.

المساهمون: Mader, R., Demay, C., Jouvin-Marche, E., Ploy, M. -C., Barraud, O., Bernard, S., Lacotte, Y., Pulcini, C., Weinbach, J., Berling, C., Bouqueau, M., Hlava, A., Habl, C., Kernstock, E., Strauss, R., Muchl, R., Buhmann, V., Versporten, A., Ingenbleek, A., Vandael, E., Haelterman, G., De Raedt, L., Hunjak, B., Raickovic, B., Mackova, B., Niklova, E., Zemlickova, H., Hrivnakova, L., Jindrak, V., Kristensen, B., Lyndrup, M., Skovgaard, S., Wolf Sonksen, U., Aasmae, B., Ruut, J., Linnik, L., Sadikova, O., Martin, P., Zanuzdana, A., Kizilkaya-Guneser, G., Oezcelik, N., Eckmanns, T., Lambrou, A., Kontopidou, F., Papadaki, M., Tsana, M., Maroulis, N., Vatopoulos, A., Papadogiannakis, E., Kontarini, M., Gikas, A., Magkanaraki, A., Cozza, A., Martinelli, D., Fortunato, F., Prato, R., Marella, A. M., Pantosti, A., Prestinaci, F., Busani, L., Pezzoti, P., Creti, R., Martoccia, R. M., Brusaferro, S., Vilde, A., Jakovela, A., Langusa, E., Grudule, L., Grinsteine, M., Dumpis, U., Dambrauskiene, A., Vitkauskiene, A., Tirvaite, D., Cemnalianskis, L., Kazenaite, E., Lozoraitiene, I., Adomaitiene, R., Ambrazaitiene, R., Kiveryte, S., Maciulaityte, A., Kuklyte, J., Petrene, J., Valinteliene, R., Kanapeckiene, V., Razmiene, A., Kairiene, B., Aleksiene, G., Valinciute, G., Petraitis, R., Elsemulder, A., Nakched, A., Claessen, J., Gui, L., Kort, M. D., Peran, R., Van Leeuwen, A., Smeets, E., Mennen, M., Spruijt, P., Westerhof, R.

مصطلحات موضوعية: Animal, Anti-Bacterial Agent, Bacteria, Cat, Cattle, Chicken, Dog, Drug Resistance, Bacterial, Female, Swine, One Health

الوصف: Background: Building the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen the European One Health antimicrobial resistance (AMR) surveillance approach. Objectives: To define the combinations of animal species/production types/age categories/bacterial species/specimens/antimicrobials to be monitored in EARS-Vet. Methods: The EARS-Vet scope was defined by consensus between 26 European experts. Decisions were guided by a survey of the combinations that are relevant and feasible to monitor in diseased animals in 13 European countries (bottom-up approach). Experts also considered the One Health approach and the need for EARS-Vet to complement existing European AMR monitoring systems coordinated by the ECDC and the European Food Safety Authority (EFSA). Results: EARS-Vet plans to monitor AMR in six animal species [cattle, swine, chickens (broilers and laying hens), turkeys, cats and dogs], for 11 bacterial species (Escherichia coli, Klebsiella pneumoniae, Mannheimia haemolytica, Pasteurella multocida, Actinobacillus pleuropneumoniae, Staphylococcus aureus, Staphylococcus pseudintermedius, Staphylococcus hyicus, Streptococcus uberis, Streptococcus dysgalactiae and Streptococcus suis). Relevant antimicrobials for their treatment were selected (e.g. tetracyclines) and complemented with antimicrobials of more specific public health interest (e.g. carbapenems). Molecular data detecting the presence of ESBLs, AmpC cephalosporinases and methicillin resistance shall be collected too. Conclusions: A preliminary EARS-Vet scope was defined, with the potential to fill important AMR monitoring gaps in the animal sector in Europe. It should be reviewed and expanded as the epidemiology of AMR changes, more countries participate and national monitoring capacities improve.

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000759761100041; volume:77; issue:3; firstpage:816; lastpage:826; numberofpages:11; journal:JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY; http://hdl.handle.net/11390/1225038Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85125212615

الإتاحة: https://doi.org/10.1093/jac/dkab462Test
http://hdl.handle.net/11390/1225038Test

المؤلفون: Reid, CJ, Cummins, ML, Börjesson, S, Brouwer, MSM, Hasman, H, Hammerum, AM, Roer, L, Hess, S, Berendonk, T, Nešporová, K, Haenni, M, Madec, J-Y, Bethe, A, Michael, GB, Schink, A-K, Schwarz, S, Dolejska, M, Djordjevic, SP

مصطلحات موضوعية: Animals, Cattle, Drug Resistance, Microbial, Escherichia coli, Escherichia coli Infections, Evolution, Molecular, Genome, Bacterial, Genomic Islands, Genomics, Host Specificity, Humans, Phylogeny, Plasmids, Poultry, Species Specificity, Swine, Virulence, Virulence Factors

الوصف: Escherichia coli ST58 has recently emerged as a globally disseminated uropathogen that often progresses to sepsis. Unlike most pandemic extra-intestinal pathogenic E. coli (ExPEC), which belong to pathogenic phylogroup B2, ST58 belongs to the environmental/commensal phylogroup B1. Here, we present a pan-genomic analysis of a global collection of 752 ST58 isolates from diverse sources. We identify a large ST58 sub-lineage characterized by near ubiquitous carriage of ColV plasmids, which carry genes encoding virulence factors, and by a distinct accessory genome including genes typical of the Yersiniabactin High Pathogenicity Island. This sub-lineage includes three-quarters of all ExPEC sequences in our study and has a broad host range, although poultry and porcine sources predominate. By contrast, strains isolated from cattle often lack ColV plasmids. Our data indicate that ColV plasmid acquisition contributed to the divergence of the major ST58 sub-lineage, and different sub-lineages inhabit poultry, swine and cattle.

وصف الملف: Electronic; application/pdf

العلاقة: http://purl.org/au-research/grants/arc/LP150100912Test; Nat Commun; Nat Commun, 2022, 13, (1), pp. 683; http://hdl.handle.net/10453/155861Test

الإتاحة: http://hdl.handle.net/10453/155861Test

المؤلفون: Nunez-Garcia, J., AbuOun, M., Storey, N., Brouwer, M, S, Delgado-Blas, J, F, Mo, S, S, Ellaby, N., Veldman, K, T, Haenni, Marisa, Châtre, P., Madec, J, Y, Hammerl, J, A, Serna, C., Getino, M., La Ragione, R., Naas, T., Telke, A, A, Glaser, Philippe, Sunde, M., Gonzalez-Zorn, B., Ellington, M, J, Anjum, M, F

المساهمون: Animal and Plant Health Agency Addlestone, UK (APHA), Wageningen BioVeterinary Research, Wageningen University and Research Wageningen (WUR), Universidad Complutense de Madrid = Complutense University of Madrid Madrid (UCM), Norwegian Veterinary Institute Oslo, Public Health England London, Unité Antibiorésistance et Virulence Bactériennes (AVB), Laboratoire de Lyon ANSES, Université de Lyon-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)-Université de Lyon-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), German Federal Institute for Risk Assessment Berlin (BfR), University of Surrey (UNIS), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Écologie et Évolution de la Résistance aux Antibiotiques / Ecology and Evolution of Antibiotics Resistance (EERA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Saclay-Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), European Project: 773830, H2020-SFS-2017-1 ,One Health EJP(2018)

المصدر: ISSN: 2045-2322.

مصطلحات موضوعية: MESH: Escherichia coli, MESH: Escherichia coli Infections, MESH: Microbial Sensitivity Tests, MESH: High-Throughput Nucleotide Sequencing, MESH: Drug Resistance, Bacterial, MESH: Computational Biology, MESH: Anti-Bacterial Agents, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology

الوصف: International audience ; Abstract Improvements in cost and speed of next generation sequencing (NGS) have provided a new pathway for delivering disease diagnosis, molecular typing, and detection of antimicrobial resistance (AMR). Numerous published methods and protocols exist, but a lack of harmonisation has hampered meaningful comparisons between results produced by different methods/protocols vital for global genomic diagnostics and surveillance. As an exemplar, this study evaluated the sensitivity and specificity of five well-established in-silico AMR detection software where the genotype results produced from running a panel of 436 Escherichia coli were compared to their AMR phenotypes, with the latter used as gold-standard. The pipelines exploited previously known genotype–phenotype associations. No significant differences in software performance were observed. As a consequence, efforts to harmonise AMR predictions from sequence data should focus on: (1) establishing universal minimum to assess performance thresholds (e.g. a control isolate panel, minimum sensitivity/specificity thresholds); (2) standardising AMR gene identifiers in reference databases and gene nomenclature; (3) producing consistent genotype/phenotype correlations. The study also revealed limitations of in-silico technology on detecting resistance to certain antimicrobials due to lack of specific fine-tuning options in bioinformatics tool or a lack of representation of resistance mechanisms in reference databases. Lastly, we noted user friendliness of tools was also an important consideration. Therefore, our recommendations are timely for widespread standardisation of bioinformatics for genomic diagnostics and surveillance globally.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35999234; info:eu-repo/grantAgreement//773830/EU/Promoting One Health in Europe through joint actions on foodborne zoonoses, antimicrobial resistance and emerging microbiological hazards./One Health EJP; anses-04019418; https://anses.hal.science/anses-04019418Test; https://anses.hal.science/anses-04019418/documentTest; https://anses.hal.science/anses-04019418/file/Nunez%E2%80%91Garcia_WGSharmonization_SciRep2022.pdfTest; PUBMED: 35999234; PUBMEDCENTRAL: PMC9396611

الإتاحة: https://doi.org/10.1038/s41598-022-16760-9Test
https://anses.hal.science/anses-04019418Test
https://anses.hal.science/anses-04019418/documentTest
https://anses.hal.science/anses-04019418/file/Nunez%E2%80%91Garcia_WGSharmonization_SciRep2022.pdfTest

المؤلفون: Mader, R., Jarrige, N., Haenni, Marisa, Bourély, C., Madec, J.-Y., Amat, J.-P.

المساهمون: Unité Antibiorésistance et Virulence Bactériennes (AVB), Laboratoire de Lyon ANSES, Université de Lyon-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)-Université de Lyon-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Unité Epidémiologie et Appui à la Surveillance (EAS), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)

المصدر: ISSN: 0950-2688.

مصطلحات موضوعية: Animal, antimicrobial resistance, evaluation, surveillance, veterinary epidemiology, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology

الوصف: International audience ; Abstract Antimicrobial resistance is a One Health issue requiring the development of surveillance systems in the human, environmental and animal sectors. In the European Economic Area, the surveillance of antimicrobial resistance in zoonotic pathogens and indicator bacteria in healthy food-producing animals is required legally, while countries are also expected to extend their surveillance to diseased animals in the frame of national action plans. In this context, evaluating existing antimicrobial resistance surveillance systems in animal health is important to improve systems in place, but also to help other countries learn from these experiences, understand success factors and anticipate challenges. With this aim, the French surveillance network for antimicrobial resistance in bacteria from diseased animals (RESAPATH) was evaluated using the Outil d'Analyse des Systèmes d'Information en Santé (OASIS) assessment tool. Key performance factors included (i) a strong and inclusive central institutional organisation defining clear and well-accepted surveillance objectives, scope and procedures, (ii) strong skills in epidemiology and microbiology and (iii) a win–win approach enabling the voluntary participation of 71 field laboratories and where free annual proficiency testing plays a pivotal role. The main area for improvement of RESAPATH was its time-consuming data management system.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33877045; anses-04019377; https://anses.hal.science/anses-04019377Test; https://anses.hal.science/anses-04019377/documentTest; https://anses.hal.science/anses-04019377/file/Mader_Oasis_EI2021.pdfTest; PUBMED: 33877045; PUBMEDCENTRAL: PMC8161364

الإتاحة: https://doi.org/10.1017/s0950268821000856Test
https://anses.hal.science/anses-04019377Test
https://anses.hal.science/anses-04019377/documentTest
https://anses.hal.science/anses-04019377/file/Mader_Oasis_EI2021.pdfTest

المؤلفون: Bergot, M, Martins-Simoes, P, Kilian, H, Chatre, P, Worthing, KA, Norris, JM, Madec, J-Y, Laurent, F, Haenni, M

الوصف: Staphylococcus pseudintermedius is a colonizer as well as an important pathogen of dogs where it is responsible for skin, ear and post-operative infections. The emergence of methicillin-resistant S. pseudintermedius (MRSP) in the early 2000s, which were additionally resistant to most veterinary-licensed antibiotics, drew specific attention to these pathogens due to the limitations created in veterinary therapeutic options. Multiple studies showed that the sequence type (ST)71 was the most frequently identified clone in Europe. A few years ago, several publications have suggested a decline of the ST71 clone and the emergence of the ST258 lineage in Northern Europe. In this study, we show that ST71 is also decreasing over time in France and that the non-ST71 population is highly heterogeneous. Globally, the non-ST71 clones are more susceptible to antibiotics, which might be good news for veterinarians. Two other lineages, ST258 and ST496, seem to be successful in France. These isolates, as well as representatives of the ST71 clone, underwent whole-genome sequence. This study shows that the ST71 and ST496 clusters are highly homogenous while the ST258 cluster is more diverse. Each ST possesses a specific pattern of resistance and virulence genes. The reasons for the apparent and simultaneous success of the ST258 and ST496 clones remain unclear. But the emergence of the ST496 clone will require monitoring given its multi-resistant genotype and threat to canine health.

العلاقة: Bergot, M., Martins-Simoes, P., Kilian, H., Chatre, P., Worthing, K. A., Norris, J. M., Madec, J. -Y., Laurent, F. & Haenni, M. (2018). Evolution of the Population Structure of Staphylococcus pseudintermedius in France. FRONTIERS IN MICROBIOLOGY, 9 (DEC), https://doi.org/10.3389/fmicb.2018.03055Test.; http://hdl.handle.net/11343/253632Test

الإتاحة: https://doi.org/10.3389/fmicb.2018.03055Test
http://hdl.handle.net/11343/253632Test

المؤلفون: Harris, S, Piotrowska, MJ, Goldstone, RJ, Qi, R, Foster, G, Dobrindt, U, Madec, J-Y, Valat, C, Rao, FV, Smith, DGE

المصدر: Harris , S , Piotrowska , MJ , Goldstone , RJ , Qi , R , Foster , G , Dobrindt , U , Madec , J-Y , Valat , C , Rao , FV & Smith , DGE 2018 , ' Variant O89 O-antigen of E.coli is associated with group 1 capsule loci and multidrug resistance ' , Frontiers in Microbiology , vol. 9 , no. AUG , 2026 . https://doi.org/10.3389/fmicb.2018.02026Test

مصطلحات موضوعية: Escherichia coli, Group 1 capsule, Lipopolysaccharide, Multidrug resistance (MDR), Novel O-antigen, Quantitative proteomics

الوصف: Bacterial surface polysaccharides play significant roles in fitness and virulence. In Gram-negative bacteria such as Escherichia coli, major surface polysaccharides are lipopolysaccharide (LPS) and capsule, representing O- and K-antigens, respectively. There are multiple combinations of O:K types, many of which are well-characterized and can be related to ecotype or pathotype. In this investigation, we have identified a novel O:K permutation resulting through a process of major genome reorganization in a clade of E. coli. A multidrug-resistant, extended-spectrum b-lactamase (ESBL)- producing strain – E. coli 26561 – represented a prototype of strains combining a locus variant of O89 and group 1 capsular polysaccharide. Specifically, the variant O89 locus in this strain was truncated at gnd, flanked by insertion sequences and located between nfsB and ybdK and we apply the term O89m for this variant. The prototype lacked colanic acid and O-antigen loci between yegH and hisI with this tandem polysaccharide locus being replaced with a group 1 capsule (G1C) which, rather than being a recognized E. coli capsule type, this locus matched to Klebsiella K10 capsule type. A genomic survey identified more than 200 E. coli strains which possessed the O89m locus variant with one of a variety of G1C types. Isolates from our collection with the combination of O89m and G1C all displayed a mucoid phenotype and E. coli 26561 was unusual in exhibiting a mucoviscous phenotype more recognized as a characteristic among Klebsiella strains. Despite the locus truncation and novel location, all O89m:G1C strains examined showed a ladder pattern typifying smooth LPS and also showed high molecular weight, alcian blue-staining polysaccharide in cellular and/or extra-cellular fractions. Expression of both O-antigen and capsule biosynthesis loci were confirmed in prototype strain 26561 through quantitative proteome analysis. Further in silico exploration of more than 200 E. coli strains possessing the O89m:G1C combination identified a very high ...

وصف الملف: application/pdf

العلاقة: https://pure.sruc.ac.uk/en/publications/e4ead792-f4be-47c8-a72d-b8acae7d3ca9Test

الإتاحة: https://doi.org/10.3389/fmicb.2018.02026Test
https://pure.sruc.ac.uk/en/publications/e4ead792-f4be-47c8-a72d-b8acae7d3ca9Test
https://pure.sruc.ac.uk/ws/files/15264862/14922.pdfTest

المؤلفون: Valat, C., Haenni, M., Arnaout, Y., Drapeau, A., Hirchaud, E., Touzain, F., Boyer, T., Delannoy, S., Vorimore, F., Fach, P., Madec, J.-Y.

المصدر: Letters in Applied Microbiology ; volume 75, issue 2, page 355-362 ; ISSN 1472-765X 0266-8254

مصطلحات موضوعية: Applied Microbiology and Biotechnology

الوصف: Necrotoxigenic Escherichia coli 2 (NTEC2) are defined as E. coli producing the toxin known as cytotoxic necrotizing factor 2 (CNF2), a potent toxin primarily found in bovine but also in humans. NTEC2 are mostly associated with bovine, and cnf2 is known to be carried by pVir-like plasmids. In this study, we looked for NTEC2 in a collection of E. coli collected between 2011 and 2018 in French bovine. Thirty-two isolates, collected from both sick (n = 19) and healthy (n = 13) animals, were identified and characterized using whole-genome sequencing. One F74 plasmid of this bacterial collection was long-read sequenced: its size was 138 121 bp and it carried the cnf2, F17cA-eG, cdtB, iutA, iucC and ompP virulence factors (VFs), but no resistance gene. A large variety of genetic backgrounds was observed, but all cnf2-carrying plasmids belonged to the IncF family, and most of them (78·1%) were of the F74 group. Similar F74 plasmids were also reported from bovine in the United Kingdom and the United States, as identified in the publically available databases. Consequently, these F74 plasmids, which are widely disseminated among E. coli from cattle in the French territory, are vectors of virulence determinants that largely went unnoticed until now.

الإتاحة: https://doi.org/10.1111/lam.13733Test
https://academic.oup.com/lambio/article-pdf/75/2/355/48738212/lambio0355.pdfTest

المؤلفون: Madec, J.-Y., Haenni, M., Nordmann, P., Poirel, L.

المساهمون: French agency for food, environmental and occupational health safety (ANSES, France), Faculty of Science, University of Fribourg (Switzerland)

المصدر: Clinical Microbiology and Infection ; volume 23, issue 11, page 826-833 ; ISSN 1198-743X

مصطلحات موضوعية: Infectious Diseases, Microbiology (medical), General Medicine

الإتاحة: https://doi.org/10.1016Test/j.cmi.2017.01.013
https://api.elsevier.com/content/article/PII:S1198743X17300460?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1198743X17300460?httpAccept=text/plainTest

المؤلفون: Mader, R., Demay, C., Jouvin-Marche, E., Ploy, M. -C., Barraud, O., Bernard, S., Lacotte, Y., Pulcini, C., Weinbach, J., Berling, C., Bouqueau, M., Hlava, A., Habl, C., Kernstock, E., Strauss, R., Muchl, R., Buhmann, V., Versporten, A., Ingenbleek, A., Vandael, E., Haelterman, G., De Raedt, L., Hunjak, B., Raickovic, B., Mackova, B., Niklova, E., Zemlickova, H., Hrivnakova, L., Jindrak, V., Kristensen, B., Lyndrup, M., Skovgaard, S., Wolf Sonksen, U., Aasmae, B., Ruut, J., Linnik, L., Sadikova, O., Martin, P., Zanuzdana, A., Kizilkaya-Guneser, G., Oezcelik, N., Eckmanns, T., Lambrou, A., Kontopidou, F., Papadaki, M., Tsana, M., Maroulis, N., Vatopoulos, A., Papadogiannakis, E., Kontarini, M., Gikas, A., Magkanaraki, A., Cozza, A., Martinelli, D., Fortunato, F., Prato, R., Marella, A. M., Pantosti, A., Prestinaci, F., Busani, L., Pezzoti, P., Creti, R., Martoccia, R. M., Brusaferro, S., Vilde, A., Jakovela, A., Langusa, E., Grudule, L., Grinsteine, M., Dumpis, U., Dambrauskiene, A., Vitkauskiene, A., Tirvaite, D., Cemnalianskis, L., Kazenaite, E., Lozoraitiene, I., Adomaitiene, R., Ambrazaitiene, R., Kiveryte, S., Maciulaityte, A., Kuklyte, J., Petrene, J., Valinteliene, R., Kanapeckiene, V., Razmiene, A., Kairiene, B., Aleksiene, G., Valinciute, G., Petraitis, R., Elsemulder, A., Nakched, A., Claessen, J., Gui, L., Kort, M. D., Peran, R., Van Leeuwen, A., Smeets, E., Mennen, M., Spruijt, P., Westerhof, R., Skulberg, A., Bakka, E. Ro., Miard, K., Henricsen, S. Ho., Pellerud, A., Kallberg, C., Ardal, C., Eriksen, H. -M., Kranstad, K., Molvik, M., Kacelnik, O., Sollund, P., Samuelsen, R., Bakke, T., Urdahl, A. M., Norstrom, M., Olczak-Pienkowska, A., Skoczynska, A., Zabicka, D., Bysiek, J., Rekawek, J., Lebre, A., Falcao, E., Scripcaru, G., Neves, I., Gomes, S., Pereira, N., Malutan, A. M., Iuhas, C., Szakacs, L., Kissiedou-Bob, M., Ciortea, R., Grilc, E., Klavs, I., Turk, K., Subelj, M., Vrdelja, M., Serdt, M., Jemec, N., Glavan, U., Simonovic, Z., Tamayo, A. N., Lopez Navas, A., Munoz Madero, C., Alonso Lebrero, J. L., Alonso Irujo, L., Santacreu Garcia, M., Crespo Robledo, P., Oliva, G., Massanes, M., Oliver Palomo, A., Garcia Pineda, A., Ferragut, E., Rojo, E., Castano, E., Perianez, L., Torres Cantero, A. M., Jimenez Guillen, C., Hukelova, H., Alcaraz, M., Carlos, M. A., Lopez Acuna, M. D. P., Gil Setas, A., Ibarrola Segura, A., Ezpeleta, C., Gahigiro Merino, C., Portillo Bordonabe, M. E., Fragoso, M., Beristain Rementeria, X., Penalva, G., Cisneros, J. M., Estevez, M., Monteau, S., Del Rio, L., Gonzalez De Suso, M. J., Gallego Berciano, P., Aranguren Oyarzabal, A., Alioto, D., Izquierdo Palomares, J. M., Calvo Alcantara, M. J., Gonzalez Perez, R., Havarria, T., Hulth, A., Carlin, K., Edman, L., Grape, M., Aspevall, O., Haggar, A., Lindal, E., Burgos, A., Ottoson, J., Ostman, M., Egervarn, M., Nordenfelt, A., Bengtsson, B., Soderman, I., Bjers, A., Jonsson, J. -I., Starborg, M., Laine, M., Fagerstedt, P., Metcalfe, A., Soder, J., Lytsy, B., Madec, J. Y., Collineau, L., Berger-Carbonne, A., Colomb-Cotinat, M., Bourely, C., Amat, J. -P., Broens, E. M., Callens, B., Crespo-Robledo, P., Damborg, P., Filippitzi, M. -E., Fitzgerald, W., Gronthal, T., Haenni, M., Heuvelink, A., Van Hout, J., Kaspar, H., Pedersen, K., Pokludova, L., Dal Pozzo, F., Slowey, R., Zafeiridis, C., Madec, J. -Y.

المساهمون: Departments of Faculty of Veterinary Medicine

المصدر: Journal of Antimicrobial Chemotherapy, 77(3), 816. Oxford University Press
EU-JAMRAI 2022, ' Defining the scope of the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) : a bottom-up and One Health approach ', The Journal of antimicrobial chemotherapy, vol. 77, no. 3, pp. 816-826 . https://doi.org/10.1093/jac/dkab462Test
Journal of antimicrobial chemotherapy, Oxford : Oxford University Press, 2022, vol. 77, iss. 3, p. 816-826
bioRxiv

مصطلحات موضوعية: Microbiology (medical), Veterinary medicine, Staphylococcus pseudintermedius, 040301 veterinary sciences, Swine, Drug Resistance, 413 Veterinary science, 0403 veterinary science, Animals, Anti-Bacterial Agents, Bacteria, Cats, Cattle, Chickens, Dogs, Drug Resistance, Bacterial, Female, One Health, 03 medical and health sciences, Antibiotic resistance, Antimicrobial stewardship, Medicine, Pharmacology (medical), 2. Zero hunger, Streptococcus uberis, Pharmacology, 0303 health sciences, biology, 030306 microbiology, business.industry, Bacterial, 04 agricultural and veterinary sciences, biology.organism_classification, Antimicrobial, Food safety, 3. Good health, Infectious Diseases, business, Streptococcus dysgalactiae

الوصف: BackgroundBuilding the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen the European One Health antimicrobial resistance (AMR) surveillance approach.ObjectivesThe objectives were to (i) define the combinations of animal species, production types, age categories, bacterial species, specimens and antimicrobials to be monitored in EARS-Vet and to (ii) determine antimicrobial test panels able to cover most combinations.MethodsThe EARS-Vet scope was defined by consensus between 26 European experts. Decisions were guided by a survey of the combinations that are relevant and feasible to monitor in diseased animals in 13 European countries (bottom-up approach). Experts also considered the One Health approach and the need for EARS-Vet to complement existing European AMR monitoring systems coordinated by the European Centre for Disease Prevention and Control (ECDC) and the European Food Safety Authority (EFSA).ResultsEARS-Vet would monitor AMR in six animal species (cattle, swine, chicken (broiler and laying hen), turkey, cat and dog), for 11 bacterial species (Escherichia coli, Klebsiella pneumoniae, Mannheimia haemolytica, Pasteurella multocida, Actinobacillus pleuropneumoniae, Staphylococcus aureus, Staphylococcus pseudintermedius, Staphylococcus hyicus, Streptococcus uberis, Streptococcus dysgalactiae and Streptococcus suis). Relevant antimicrobials for their treatment were selected (e.g. tetracyclines) and complemented with antimicrobials of more specific public health interest (e.g. carbapenems). Three test panels of antimicrobials were proposed covering most EARS-Vet combinations of relevance for veterinary antimicrobial stewardship.ConclusionsWith this scope, EARS-Vet would enable to better address animal health in the strategy to mitigate AMR and better understand the multi-sectoral AMR epidemiology in Europe.

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c03cd9abbc31dd8e611ee23aebf903Test
https://hdl.handle.net/1874/419152Test

المؤلفون: Blanc, V., Leflon-Guibout, V., Blanco, J., Haenni, M., Madec, J.-Y., Rafignon, G., Bruno, P., Mora, A., Lopez, C., Dahbi, G., Dunais, B., Anastay, M., Branger, C., Moreau, R., Pradier, C., Nicolas-Chanoine, M.-H.

المصدر: Journal of Antimicrobial Chemotherapy ; volume 69, issue 5, page 1231-1237 ; ISSN 0305-7453 1460-2091

مصطلحات موضوعية: Infectious Diseases, Pharmacology (medical), Pharmacology, Microbiology (medical)

الإتاحة: https://doi.org/10.1093/jac/dkt519Test
http://academic.oup.com/jac/article-pdf/69/5/1231/1986989/dkt519.pdfTest