نتائج البحث - "MTT, 3-(4,5-dimethylthiazol-2-yl)− 2,5-diphenyltetrazolium bromide"

المساهمون: Gugliotta, Gabriele, Sudo, Makoto, Cao, Qi, Lin, De-chen, Sun, Haibo, Takao, Sumiko, Le Moigne, Ronan, Rolfe, Mark, Gery, Sigal, Müschen, Marku, Cavo, Michele, Koeffler, H. Phillip

المصدر: Neoplasia (New York, N.Y.), vol 19, iss 10
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 10, Pp 750-761 (2017)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: PEI, polyethylenimine, 0301 basic medicine, Cancer Research, Apoptosis, ERAD, ER-associated degradation, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Gene Knockout Techniques, chemistry.chemical_compound, UPR, unfolded protein response, Valosin Containing Protein, Molecular Targeted Therapy, Endoplasmic Reticulum Chaperone BiP, Tumor, Cell Cycle, Drug Synergism, Precursor Cell Lymphoblastic Leukemia-Lymphoma, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Endoplasmic Reticulum Stress, Biochemistry, Signal Transduction, medicine.drug, Original article, Vincristine, Programmed cell death, XBP1, HNA, 2-hydroxy-1-naphthaldehyde, Cell Survival, Clinical Sciences, B-ALL, B acute lymphoblastic leukemia, Antineoplastic Agents, Biology, lcsh:RC254-282, 4-OHT, 4-hydroxy tamoxifen, Cell Line, ER, endoplasmic reticulum, PI, propidium iodide, 03 medical and health sciences, Cell Line, Tumor, medicine, Humans, Oncology & Carcinogenesis, Propidium iodide, Cell Proliferation, Endoplasmic reticulum, 030104 developmental biology, Gene Expression Regulation, chemistry, Cell culture, Unfolded Protein Response, Cancer research, Unfolded protein response, Biomarkers

وصف الملف: application/pdf; ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513f1ad0f44ffe57cf442f239234105fTest
https://doi.org/10.1016/j.neo.2017.08.001Test

37

ABT-737 Synergizes with Cisplatin Bypassing Aberration of Apoptotic Pathway in Non-small Cell Lung Cancer

المؤلفون: Arum Kim, Eun Young Kim, Yoon Soo Chang, Se Kyu Kim, Ji Ye Jung

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 4, Pp 354-363 (2017)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Lung Neoplasms, DFS, disease-free survival, Gene Expression, Apoptosis, Piperazines, Nitrophenols, Mice, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Carcinoma, Non-Small-Cell Lung, Cytotoxic T cell, STAT3, Sulfonamides, biology, FFPE, formalin-fixed paraffin embedded, Drug Synergism, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, Tumor Burden, Proto-Oncogene Proteins c-bcl-2, Female, IHC, immunohistochemistry, Signal Transduction, medicine.drug, STAT3 Transcription Factor, Original article, DNA damage, lcsh:RC254-282, OS, overall survival, 03 medical and health sciences, In vivo, Cell Line, Tumor, NSCLC, non-small cell lung cancer, medicine, Animals, Humans, Lung cancer, Aged, Neoplasm Staging, Cisplatin, Biphenyl Compounds, CI, combination index, medicine.disease, Xenograft Model Antitumor Assays, Molecular biology, RT-PCR, real-time PCR, Disease Models, Animal, 030104 developmental biology, Cell culture, biology.protein, Cancer research, Neoplasm Grading, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf7861287b6c8a0c7a85904e30f8700Test

38

Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB

المؤلفون: Claudia Moriconi, Valerio Licursi, Giuseppe Lupo, Emanuela D'Acunto, Emanuele Cacci, Elena Miranda, Nicoletta Carucci, Noemi Antonella Guadagno, Rodolfo Negri, Antonella De Jaco, Paola S. Nisi

المصدر: Neurobiology of Disease
Neurobiology of Disease, Vol 103, Iss, Pp 32-44 (2017)

مصطلحات موضوعية: 0301 basic medicine, Polymers, Epilepsies, Myoclonic, Protein conformational disease, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Mice, FENIB, familial encephalopathy with neuroserpin inclusion bodies, GST, glutathione transferase, Cells, Cultured, ApoE, apolipoprotein E, Neurons, Cerebral Cortex, wild type, WT, GPx, glutathione peroxidase, Neurodegeneration, HRP, horseradish peroxidase, Prdx6, peroxiredoxin 6, 3. Good health, Scara, scavenger receptor class A, Neurology, Heredodegenerative Disorders, Nervous System, Intracellular, Familial encephalopathy with neuroserpin inclusion bodies, NS, neuroserpin, Cell Survival, Neuroserpin, Mice, Transgenic, Biology, Serpin, Article, lcsh:RC321-571, Neural progenitor cells, Oxidative stress, Serpin polymers, ER, endoplasmic reticulum, 03 medical and health sciences, SOD, superoxide dismutase, medicine, unfolded protein response, UPR, Animals, Humans, A1AT, alpha1 antitrypsin, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Serpins, Endoplasmic reticulum, Neuropeptides, Wild type, medicine.disease, Molecular biology, Oxidative Stress, 030104 developmental biology, NFκB, nuclear factor κB, Unfolded protein response, Aldh, aldehyde dehydrogenase, Dementia

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80be70f0ed1b0fc6e7f713e96db2e01Test
http://europepmc.org/articles/PMC5439028Test

39

Synergistic antitumor activity of rapamycin and EF24 via increasing ROS for the treatment of gastric cancer

المؤلفون: Jiansong Ji, Ri Cui, Xiaoxi Fan, Peng Zou, Fazong Wu, Weiqian Chen, Xi Chen, Qianqian Zhang, Rajamanickam Vinothkumar, Guang Liang, Zhongwei Zhao

المصدر: Redox Biol
Redox Biology, Vol 10, Iss C, Pp 78-89 (2016)
Redox Biology

مصطلحات موضوعية: 0301 basic medicine, ATF4, activating transcription factor 4, Cytotoxicity, Clinical Biochemistry, PI, propidium Iodide, Pharmacology, Biochemistry, JC-1, cationic carbocyanine dye, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Mice, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, CHOP, CAAT/enhancer binding protein (C/EBP) homologous protein, cdc-2, cyclin-dependent kinase 1 (cell division cycle protein 2), lcsh:QH301-705.5, EF24, lcsh:R5-920, Kinase, HRP, horseradish peroxidase, Drug Synergism, Endoplasmic Reticulum Stress, PI3 kinase, phosphoinositide 3-kinase, Bcl2, B-cell lymphoma 2, Gene Expression Regulation, Neoplastic, DCF, dichlorodihydrofluorescein, mTORC, mTOR complex, 030220 oncology & carcinogenesis, FITC, fluorescein isothiocyanate, lcsh:Medicine (General), Corrigendum, Research Paper, PARP, poly (ADP-ribose) polymerase, medicine.drug, Cell Survival, mTOR, mammalian target of rapamycin, MDM-2, murine double minute 2, Biology, Benzylidene Compounds, eIF2, eukaryotic initiation factor 2, ER, endoplasmic reticulum, 03 medical and health sciences, ROS, reactive oxygen species, Stomach Neoplasms, Cell Line, Tumor, medicine, Animals, Humans, Rapamycin, Piperidones, PI3K/AKT/mTOR pathway, DCFH-DA, 2′, 7′-dichlorodihydrofluorescein diacetate, Cell Proliferation, MDA, malondialdehyde, Sirolimus, 4E-BP-1, eukaryotic initiation factor 4E binding protein-1, Ki-67, nuclear protein associated with cell proliferation, Cell growth, PERK, protein kinase RNA-like endoplasmic reticulum kinase, Organic Chemistry, JNK Mitogen-Activated Protein Kinases, Cancer, Antitumor, C/EBP, CAAT/enhancer binding protein, JNK, c-Jun N terminal kinase, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, S6, S6 ribosomal protein, lcsh:Biology (General), Oxidative stress, Apoptosis, NAC, N-acetyl cysteine, Cancer cell, Unfolded protein response, Reactive Oxygen Species, Gastric cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996fc2e0f8970a6c0fa2b5a280f19672Test
https://doi.org/10.1016/j.redox.2016.09.006Test

40

In vitro prion-like behaviour of TDP-43 in ALS

المؤلفون: Roberto Simone, Yun-Ru Chen, Claire Troakes, Jia Newcombe, Rickie Patani, Phillip Smethurst, Katie Sidle

المصدر: Neurobiology of Disease, Vol 96, Iss, Pp 236-247 (2016)
Smethurst, P, Newcombe, J, Troakes, C, Simone, R, Chen, Y-R, Patani, R & Sidle, K 2016, ' In vitro prion-like behaviour of TDP-43 in ALS ', Neurobiology of Disease . https://doi.org/10.1016/j.nbd.2016.08.007Test
Neurobiology of Disease

مصطلحات موضوعية: 0301 basic medicine, Male, TDP-43, Cell, Seeding, pTDP-43, phosphorylated TDP-43, WB, Western blotting, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Mice, Neuroblastoma, 0302 clinical medicine, Amyotrophic lateral sclerosis, FCX, Frontal cortex, Propagation, Motor Neurons, MC, Motor cortex, NC, Normal control, Brain, Cell biology, DNA-Binding Proteins, medicine.anatomical_structure, Spinal Cord, Neurology, Phosphorylation, Protein folding, Female, PDC, Parkinson's disease control, Autopsy, Protein misfolding, Green Fluorescent Proteins, Biology, Transfection, Article, Prion Proteins, lcsh:RC321-571, 03 medical and health sciences, mental disorders, medicine, SC L, Spinal cord Lumbar, Animals, Humans, Viability assay, TCX, Temporal cortex, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, TDP-O, TDP-43 Oligomer, SK, Sarkosyl extract, SS, Sarkosyl soluble, IF, Immunofluorescence, Amyotrophic Lateral Sclerosis, nutritional and metabolic diseases, SI, Sarkosyl Insoluble, NSC-34, Neuroblastoma spinal cord-34, Motor neuron, medicine.disease, In vitro, Coculture Techniques, nervous system diseases, 030104 developmental biology, HEK293 Cells, Cell culture, ALS, Prion-like disease, FL WT, Full length wild type TDP-43 plasmid, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b4b5ad9cf546a7b3468cf5b9663216Test
http://www.sciencedirect.com/science/article/pii/S0969996116301954Test

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