المؤلفون: Trager, Lena E., Lyons, Margaret, Kuznetsov, Alexandra, Sheffield, Cedric, Roh, Kangsan, Freeman, Rebecca, Rhee, James, Guseh, J. Sawalla, Li, Haobo, Rosenzweig, Anthony

المصدر: Journal of Sport and Health Science ; volume 12, issue 4, page 423-437 ; ISSN 2095-2546

مصطلحات موضوعية: Physical Therapy, Sports Therapy and Rehabilitation, Orthopedics and Sports Medicine

الإتاحة: https://doi.org/10.1016/j.jshs.2022.12.011Test
https://api.elsevier.com/content/article/PII:S2095254622001259?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2095254622001259?httpAccept=text/plainTest

المؤلفون: Rhee, James, Kuznetsov, Alexandra, McKay, Tina, Lyons, Margaret, Houstis, Nicholas, Mekkonen, Jennifer, Ethridge, Breanna, Ibala, Reine, Hahm, Eunice, Gitlin, Jacob, Guseh, J. Sawalla, Kitchen, Robert, Rosenzweig, Anthony, Shaefi, Shahzad, Flaczyk, Adam, Qu, Jason, Akeju, Oluwaseun

المساهمون: National Institute on Aging

المصدر: Frontiers in Aging Neuroscience ; volume 13 ; ISSN 1663-4365

مصطلحات موضوعية: Cognitive Neuroscience, Aging

الوصف: Background Postoperative delirium (POD) is an acute altered mental state commonly encountered after cardiac surgery. The pathophysiological mechanisms underlying POD remain unclear. We aimed to identify circulating proteins significantly altered after major cardiac surgery with cardiopulmonary bypass (CPB). We also aimed to enable inferences on associations with POD. Methods Serum and whole blood samples were collected before CPB ( n = 16 patients; n = 8 with POD) and again from the same patients on postoperative day 1. All patients were clinically evaluated for POD on postoperative days 1–3. An aptamer-based proteomics platform (SOMAscan) was used to quantify serum protein abundance in patients with POD compared with non-POD controls. We also performed a lipopolysaccharide (LPS)-based in vitro functional analysis (TruCulture) on whole blood samples from patients with POD and non-POD controls to approximate surgical stress. Cytokine levels were determined using a Luminex immunoassay. Results Cardiac surgery with CPB resulted in a significant ( p adj < 0.01) change in 48.8% (637 out of 1,305) of proteins detected by SOMAscan. Gene set enrichment showed that the most impacted biological processes involved myeloid cell activation. Specifically, activation and degranulation of neutrophils were the top five highest-scoring processes. Pathway analyses with the Kyoto Encyclopedia of Genes and Genomes (KEGG) showed that metabolic enzymes, particularly those of glycolysis, were elevated in serum concentration after surgery. Several proteins were significantly increased postoperatively in patients diagnosed with POD relative to the non-POD controls, with interleukin-6 (IL-6) showing the greatest fold-change. LPS stimulation of whole blood samples confirmed these findings. Linear regression analysis showed a highly significant correlation between Confusion Assessment Method (CAM) scores and CPB-mediated changes in cGMP-inhibited 3′,5′-cyclic phosphodiesterase A (PDE3A). Conclusions Cardiac surgery with CPB resulted ...

الإتاحة: https://doi.org/10.3389/fnagi.2021.699763Test

المؤلفون: Lyons, Margaret J.

المصدر: Women in Telecommunications ; Women in Engineering and Science ; page 35-64 ; ISSN 2509-6427 2509-6435 ; ISBN 9783031219740 9783031219757

الإتاحة: https://doi.org/10.1007/978-3-031-21975-7_2Test

المؤلفون: Gullette, Donna L., Lyons, Margaret A.

المصدر: Journal of Community Health Nursing, 2005 Apr 01. 22(1), 47-60.

الوصول الحر: https://www.jstor.org/stable/3427756Test

المؤلفون: Rhee, James, Freeman, Rebecca, Roh, Kangsan, Lyons, Margaret, Xiao, Chunyang, Zlotoff, Daniel, Yeri, Ashish, Li, Haobo, Guerra, Justin, Guseh, J. Sawalla, Kuznetsov, Alexandra, Houstis, Nicholas, Roh, Jason, Damilano, Federico, Liu, Xiaojun, Silverman, Michael, Kwong, Raymond, Das, Saumya, Rosenzweig, Anthony

المصدر: Circulation Research ; volume 133, issue 7, page 651-653 ; ISSN 0009-7330 1524-4571

الإتاحة: https://doi.org/10.1161/circresaha.123.322640Test

المؤلفون: DeCarli, Kathryn, Guyer, Dana, Lyons, Margaret, Carneiro, Benedito

المصدر: Journal of Pain and Symptom Management ; volume 65, issue 3, page e303-e304 ; ISSN 0885-3924

مصطلحات موضوعية: Anesthesiology and Pain Medicine, Neurology (clinical), General Nursing

الإتاحة: https://doi.org/10.1016/j.jpainsymman.2022.12.130Test
https://api.elsevier.com/content/article/PII:S0885392422011630?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0885392422011630?httpAccept=text/plainTest

المؤلفون: Boucher, Alexander A., Lyons, Margaret, McGann, Patrick T.

المصدر: JAMA Health Forum ; volume 4, issue 5, page e230877 ; ISSN 2689-0186

الوصف: This Viewpoint discusses developing new sickle cell disease adult care models to support specialized health care homes that are patient-focused and antiracist, rather than an approach focused mainly on financial incentives.

الإتاحة: https://doi.org/10.1001/jamahealthforum.2023.0877Test
https://jamanetwork.com/journals/jama-health-forum/articlepdf/2804950/boucher_2023_vp_230007_1683735304.45841.pdfTest

المؤلفون: Lyons, Margaret, Bartlett, Jennifer, McDonald, Paula

المصدر: Resources Policy

مصطلحات موضوعية: Australian Junior Companies, Australian Mid-tier Companies, Corporate Social Responsibility, Developing Nations, Resource Sector

الوصف: This study explores how junior and mid-tier resources companies operating in the world's most impoverished countries understand and practice corporate social responsibility (CSR) , and its relationship to their assumed social licence to operate (SLO) . The study drew on emergent research that finds smaller companies, which are less subject to scrutiny by external stakeholders such as NGOs, media and investors, understand and practice CSR differently to the multinational companies which have dominated extant research. The study found that CSR meaning and practice in this large, but little researched, group of companies was highly context-based and community focused, in marked contrast to the strategies and practices of larger resources companies operating in developing nations. Importantly, the study also revealed striking contradictions and ambiguities between participants’ CSR actions and accountability and their assumed SLO.

وصف الملف: application/pdf

العلاقة: https://eprints.qut.edu.au/222073/1/101361.pdfTest; Lyons, Margaret, Bartlett, Jennifer, & McDonald, Paula (2016) Corporate social responsibility in junior and mid-tier resources companies operating in developing nations - beyond the public relations offensive. Resources Policy, 50, pp. 204-213.; https://eprints.qut.edu.au/222073Test/; QUT Business School; School of Advertising, Marketing & Public Relations; School of Management

الإتاحة: https://doi.org/10.1016/j.resourpol.2016.10.005Test
https://eprints.qut.edu.au/222073Test/

المؤلفون: Marsh, David D., Lyons, Margaret F., Pacific Training and Technical Assistance Corp., Berkeley, CA.

تمت مراجعته من قبل الزملاء: N

Page Count: 168

Sponsoring Agency: Office of Education (DHEW), Washington, DC. Office of Planning, Budgeting, and Evaluation.

الواصفات: Elementary School Teachers, Program Evaluation, Teacher Attitudes, Teacher Background, Teacher Characteristics, Teacher Education, Teacher Education Programs, Teacher Evaluation, Teaching Skills

مستخلص: This report examines the second phase of a longitudinal impact study of the Sixth Cycle Teacher Corps. Phase 1 focused on the relationship of intern background and Teacher Corps Program characteristics to intern exit characteristics. Its goals were to: (a) contrast teacher performance and pupil gains of graduates with those of control group teachers; (b) analyze the relationship of teacher background, teacher education program, teacher performance, and pupil performance for the graduates; and (c) assess the effects of professional support which graduates and controls receive. The 84 subjects taught grades 2-6 in self-contained classrooms. Data about teacher and pupil performance were obtained through a classroom observation guide, teacher questionnaire, data, standardized reading test, and standardized self-concept scale. Graduates were superior to controls in developing ethically relevant curricula, using community resources and initiating contact with parents, and developing positive attitudes about reading development and the causes of poverty in society. Graduates facilitated greater self-concept development in pupils, but there was no significant difference in reading gains between the two groups. The consistent pattern of relationship between pupil variables and Teacher Program characteristics suggests that teacher training makes a difference on pupil behavior and on related teacher performance. (Author/HMD)

المؤلفون: Marsh, David D., Lyons, Margaret F., Pacific Training and Technical Assistance Corp., Berkeley, CA.

تمت مراجعته من قبل الزملاء: N

Page Count: 62

Sponsoring Agency: Office of Education (DHEW), Washington, DC. Office of Planning, Budgeting, and Evaluation.

الواصفات: Background, Educational Innovation, Educational Research, Higher Education, Individual Characteristics, Teacher Interns, Teachers

مستخلص: This document further analyzes a two-year Teacher Corps study which was conducted by Pacific Training and Technical Assistance Corporation for the U.S. Office of Education. The results of the first and second years of study have been reported elsewhere. This volume presents the results of a further analysis of data collected in the first year of the study dealing with the relationship between intern background characteristics and Teacher Corps program characteristics, and the teaching skills and attitudes of interns at the end of their two years of training. The goals of this study are: (a) to provide information that could serve as a bais for redirecting efforts to recruit interns, selecting new Teacher Corps projects, or providing technical assistance to projects; (b) to provide information that could be used to identify special strengths or weaknesses at any one project site and, consequently, to suggest the need for special recruiting procedures for interns or for technical assistance efforts; (c) to further explore the relationship between teacher background, Teacher Corps program characteristics as related to the teaching skills, and attitudes of interns at the end of their two years of training; and (d) to answer management-oriented questions regarding the development of effective Teacher Corps projects and the assessment of the quality and effectiveness of the projects. (A large section of the document is devoted to tables illustrating the interns' background and Teacher Corps program characteristics.) (JS)