المؤلفون: De Saint Jean, Amélie, Lucht, Frédéric, Bourlet, Thomas, Delézay, Olivier

المصدر: AIDS ; volume 28, issue 16, page 2375-2380 ; ISSN 0269-9370

الإتاحة: https://doi.org/10.1097/qad.0000000000000431Test

المؤلفون: Gagneux-Brunon, Amandine, Suy, Florence, Pouvaret, Anne, Pillet, Sylvie, Tarantino, Enrico, Bouchet, Dorothée, Fresard, Anne, Cazorla, Céline, Guglielminotti, Claire, Lucht, Frédéric, Botelho-Nevers, Elisabeth

المصدر: Journal of Clinical Virology ; volume 61, issue 1, page 173-175 ; ISSN 1386-6532

مصطلحات موضوعية: Infectious Diseases, Virology

الإتاحة: https://doi.org/10.1016/j.jcv.2014.05.019Test
https://api.elsevier.com/content/article/PII:S138665321400211X?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S138665321400211X?httpAccept=text/plainTest

المؤلفون: Botelho-Nevers, Elisabeth, Berthelot, Philippe, Verhoeven, Paul Oswald, Grattard, Florence, Cazorla, Celine, Farizon, Frederic, Pozzetto, Bruno, Lucht, Frederic

المصدر: American Journal of Infection Control ; volume 42, issue 10, page 1121-1123 ; ISSN 0196-6553

الإتاحة: https://doi.org/10.1016/j.ajic.2014.06.026Test
https://api.elsevier.com/content/article/PII:S0196655314009419?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0196655314009419?httpAccept=text/plainTest

المؤلفون: Durier, Christine, Desaint, Corinne, Lucht, Frédéric, Girard, Pierre-Marie, Lévy, Yves, May, Thierry, Michelet, Christian, Rami, Agathe, Roman, François, Delfraissy, Jean-François, Aboulker, Jean-Pierre, Launay, Odile

المساهمون: Essais Therapeutiques et Infection Par Le Vih, Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM), CIC - Biotherapie - AP-HP (cochin - Pasteur), Institut National de la Santé et de la Recherche Médicale (INSERM), Groupe Immunité des Muqueuses et Agents Pathogènes (GIMAP), Université Jean Monnet - Saint-Étienne (UJM), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Service des Maladies Infectieuses et Tropicales CHRU Nancy, Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique EHESP (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Service de médecine interne et maladies infectieuses, Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Bicêtre AP-HP, Le Kremlin-Bicêtre, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), French National Agency for Research on AIDS and Viral Hepatitis (ANRS, Paris, France), ANRS 151 study group and the REIVAC network

المصدر: ISSN: 0269-9370.

مصطلحات موضوعية: MESH: Adjuvants, Immunologic, MESH: Antibodies, Neutralizing, MESH: Hemagglutinins, MESH: Humans, MESH: Influenza A Virus, H1N1 Subtype, MESH: Influenza Vaccines, MESH: Influenza, Human, MESH: Male, MESH: Polysorbates, MESH: Prospective Studies, MESH: Single-Blind Method, MESH: Smoking, Viral, MESH: Squalene, MESH: Time Factors, MESH: alpha-Tocopherol, MESH: Antibody Formation, MESH: Drug Combinations, MESH: Female, MESH: France, MESH: HIV Infections, MESH: HIV-1, MESH: Hemagglutination Inhibition Tests, [SDV.IMM.VAC]Life Sciences [q-bio]/Immunology/Vaccinology

الوصف: International audience ; OBJECTIVE: In immunocompromised patients, alternative schedules more immunogenic than the standard influenza vaccine regimen are necessary to enhance and prolong vaccine efficacy. We previously reported that the AS03A-adjuvanted 2009 A/H1N1v vaccine yielded a higher short-term immune response than the nonadjuvanted one in HIV-1-infected adults. This study reports the long-term persistence of the immune response. DESIGN AND METHODS: In a prospective, multicenter, randomized, patient-blinded trial, two doses of AS03A-adjuvanted H1N1v vaccine containing 3.75 μg haemagglutinin (n = 155; group A) or nonadjuvanted H1N1v vaccine containing 15 μg haemagglutinin (n = 151; group B), were administered 21 days apart. Haemagglutination inhibition and neutralizing antibodies were assessed 6 and 12 months after vaccination. RESULTS: In group A and B, the seroprotection rates were 83.7 and 59.4% at month 6, and 70.4 and 49.3 at month 12, respectively. In a multivariate analysis, persistence of seroprotection 12 months after vaccination was negatively associated with current smoking (odds ratio = 0.6, P = 0.03) and positively related with the AS03A-adjuvanted H1N1v vaccine (odds ratio = 2.7, P = 0.0002). CONCLUSION: In HIV-1-infected adults, two doses of adjuvanted influenza vaccine induce long-term persistence of immune response up to 1 year after vaccination.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/23018437; hal-00875148; https://hal.science/hal-00875148Test; PUBMED: 23018437

الإتاحة: https://doi.org/10.1097/QAD.0b013e328359f27aTest
https://hal.science/hal-00875148Test

المؤلفون: Durand, François, Berthelot, Philippe, Cazorla, Celine, Farizon, Frederic, Lucht, Frederic

المصدر: International Orthopaedics ; volume 37, issue 4, page 723-727 ; ISSN 0341-2695 1432-5195

مصطلحات موضوعية: Orthopedics and Sports Medicine, Surgery

الإتاحة: https://doi.org/10.1007/s00264-013-1814-8Test

المؤلفون: Benjelloun, Fahd, Dawood, Reham, Urcuqui-Inchima, Silvio, Chanut, Blandine, Verrier, Bernard, Lucht, Frederic, Genin, Christain, Paul, Stéphane

المصدر: AIDS ; volume 27, issue 12, page 1992-1995 ; ISSN 0269-9370

الإتاحة: https://doi.org/10.1097/qad.0b013e3283632ea1Test

المؤلفون: Dawood, Reham, Benjelloun, Fahd, Pin, Jean J., Kone, Amadou, Chanut, Blandine, Jospin, Fabienne, Lucht, Frederic, Verrier, Bernard, Moog, Christaine, Genin, Christain, Paul, Stéphane

المصدر: AIDS ; volume 27, issue 5, page 717-730 ; ISSN 0269-9370

الإتاحة: https://doi.org/10.1097/qad.0b013e32835cfca5Test

المؤلفون: Suy, Florence, Botelho-Nevers, Elisabeth, Gagneux-Brunon, Amandine, Frésard, Anne, Paul, Stéphane, Lambert, Claude, Pozzetto, Bruno, Lucht, Frédéric

المصدر: AIDS ; volume 27, issue 18, page 2968-2971 ; ISSN 0269-9370

الإتاحة: https://doi.org/10.1097/qad.0000000000000022Test
http://journals.lww.com/00002030-201311280-00019Test

المؤلفون: Verhoeven, Paul O, Gagnaire, Julie, Botelho-Nevers, Elisabeth, Grattard, Florence, Carricajo, Anne, Lucht, Frédéric, Pozzetto, Bruno, Berthelot, Philippe

المصدر: Expert Review of Anti-infective Therapy ; volume 12, issue 1, page 75-89 ; ISSN 1478-7210 1744-8336

الإتاحة: https://doi.org/10.1586/14787210.2014.859985Test

المؤلفون: Botelho-Nevers, Elisabeth, Verhoeven, Paul, Paul, Stephane, Grattard, Florence, Pozzetto, Bruno, Berthelot, Philippe, Lucht, Frederic

المصدر: Expert Review of Vaccines ; volume 12, issue 11, page 1249-1259 ; ISSN 1476-0584 1744-8395

الإتاحة: https://doi.org/10.1586/14760584.2013.840091Test