يعرض 1 - 10 نتائج من 104 نتيجة بحث عن '"Lobo, Tania"', وقت الاستعلام: 1.12s تنقيح النتائج
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    دورية أكاديمية
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    دورية أكاديمية
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    دورية أكاديمية

    المصدر: Journal of Cancer Survivorship; Jun2024, Vol. 18 Issue 3, p710-726, 17p

    مستخلص: Purpose: Few studies have examined experiences of stigma and factors associated with symptoms among cervical cancer survivors from diverse racial and ethnic backgrounds. We investigated survivorship experiences and patient-reported outcomes in the SPADE symptom cluster (sleep disturbance, pain interference, anxiety, depression, and energy/fatigue) among Black, Latina, and Chinese American women diagnosed with cervical cancer. Methods: In two phases of research with cervical cancer survivors, we collected qualitative data through individual interviews (N=12; recruited through community referrals) and quantitative data from an observational cohort study (N=91; recruited through 4 national cancer registries). We coded interview transcripts to describe the survivors' experiences. We then evaluated associations between social support, spirituality, and SPADE symptom cluster domains using linear regression models. Results: Qualitative analysis yielded four themes: perceptions of stigma, empowerment, physical and psychological effects, and social support. These concepts revolved around internal and external stigmas, emotional responses, strengthened faith, and different social support types. Quantitative analyses indicated that greater spirituality was associated with lower symptom burden on all five SPADE domains (p<0.01). We observed nuanced associations between specific types of social support and SPADE domains. Conclusions: The survivorship experiences of Black, Latina, and Chinese American women with cervical cancer are negatively influenced by perceptions of stigma. Higher scores on spirituality and varied types of social support were significantly associated with fewer symptoms in the SPADE symptom cluster. Implications for Cancer Survivors: Results suggest targets for future interventions to reduce symptom burden among women diagnosed with cervical cancer by leveraging spirituality and social support. [ABSTRACT FROM AUTHOR]

    : Copyright of Journal of Cancer Survivorship is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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    دورية أكاديمية

    المصدر: Cancer. 123(2)

    الوصف: BackgroundThe Patient-Reported Outcomes Measurement Information System (PROMIS) was a National Institutes of Health-funded initiative to develop measures of symptoms and function. Responsiveness is the degree to which a measure can detect underlying changes over time. The objective of the current study was to document the responsiveness of 8 PROMIS measures in a large, population-based cancer cohort.MethodsThe Measuring Your Health study recruited 2968 patients who were diagnosed with 1 of 7 cancers between 2010 and 2012 through 4 Surveillance, Epidemiology, and End Results registries. Participants completed a baseline survey (6-13 months after diagnosis) and a 6-month follow-up survey. Changes in 8 PROMIS scores were compared with global ratings of transition, changes in performance status, and clinical events.ResultsMeasures were responsive to 6-month declines and improvements in performance status with small to large effect sizes (ES) (Cohen d = 0.34-0.71; P

    وصف الملف: application/pdf

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    دورية أكاديمية

    المساهمون: Public Health Service

    المصدر: Translational Behavioral Medicine ; volume 14, issue 4, page 241-248 ; ISSN 1869-6716 1613-9860

    مصطلحات موضوعية: Behavioral Neuroscience, Applied Psychology

    الوصف: Multilevel interventions in healthcare settings (e.g. Ask, Advise, and Connect; AAC) can reduce tobacco product use among adult patients: their effectiveness in pediatric practice is largely unknown. We implemented an AAC model in pediatric primary care to deter children’s tobacco use, and evaluated its effectiveness in a single-arm trial. At wellness visits, young patients (ages 12–17) completed a tablet-based assessment (Ask) of lifetime and current tobacco use. These data were made available within the electronic health record to pediatric primary care providers for preventive counseling (Advise). Providers then referred patients to an e-health evidence-based tobacco control intervention (Connect). Tobacco control outcomes were examined in the clinic population (N = 2219) and in a sample of patients (N = 388, 62% female, 39% non-White, M age = 15) over time, along with intervention engagement. Population use of tobacco products decreased following introduction of AAC (more than 2-fold). At the patient level, most children (80.9%) engaged with the intervention: those who were Black or African American, who never used tobacco products/were not susceptible to use, and who used fewer non-cigarette tobacco products were more likely to engage, but only after multiple prompts versus a single prompt. Engagement was positively associated with lowering children’s susceptibility to using tobacco at follow-up. A pediatric AAC model holds promise in deterring youth tobacco use, including among historically marginalized populations who may require additional support.

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    دورية أكاديمية

    المصدر: Journal of Oncology ; 2022 ; 1 ; 8

    مصطلحات موضوعية: Covid-19, SARS-CoV-2 Antibodies

    الوصف: Background: Patients with cancer and health care workers (HCW) are at higher risk for SARS-CoV-2 infection. There are limited data regarding the rate of symptomatic versus asymptomatic infection and subsequent seropositivity in both populations. Methods: We performed a prospective study of patients and HCW across two institutions during the first wave of the pandemic to analyze the prevalence of SARS-CoV-2 antibodies, the extent of associated symptoms, and durability of serologic response. Results: In 1,953 persons (733 patients and 1,220 HCW), overall seropositivity rates for 3.1% patients (95% CI 2.0-4.7) and 3.7% HCW (95% CI 2.7-4.9, p=0.520), were similar. Each institutions' seropositivity rates were numerically higher in HCW than patients. Non-Hispanic Whites and Asians had lower antibody rates (2.8%, 95% CI 2.0-3.8 and 3.3%, 95% CI 1.2-7.0) compared to Hispanics (6.9%, 95% CI 3.4-12.4) and non-Hispanic Blacks (5.9%, 95% CI 3.3-9.7), p < 0.001. Among persons with a positive SARS-CoV-2 antibody, 87% of patients and 56% of HCW did not recall having had a fever. Among HCW, administrative and technical personnel were most likely to be seropositive. The rate of persistent seropositivity at 3 months was similar between patients and HCW and was not influenced by the reporting of fever, cancer type, or therapy. Conclusion: These data suggest that patients are not at higher risk for febrile SARS-CoV-2 infections or more transient immunity than HCWs. Furthermore, racial differences and lack of association with the extent of HCW contact with COVID-19 patients suggest that community rather than hospital virus exposure was a source of many infections. ; Georgetown University ; https://doi.org/10.1155/2022/8798306Test

    العلاقة: Journal of Oncology; http://hdl.handle.net/10713/18143Test

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    دورية أكاديمية
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    دورية أكاديمية

    المصدر: LaborHistórico; ##issue.vol## 7 (2021): Número Especial - Revisitações à obra de Rosa Virgínia Mattos e Silva; 282-310 ; LaborHistórico; v. 7 (2021): Número Especial - Revisitações à obra de Rosa Virgínia Mattos e Silva; 282-310 ; LaborHistórico; Vol. 7 (2021): Número Especial - Revisitações à obra de Rosa Virgínia Mattos e Silva; 282-310 ; 2359-6910 ; 10.24206/lh.v7iespec

    الوصف: Em 5 de outubro de 1988, promulgou-se a Constituição da República Federativa do Brasil de 1988 – a Constituição cidadã –, considerada o marco do início da Nova República, que finda, segundo a historiadora francesa Maud Chirio (2018), com a última eleição presidencial, ocorrida em 2018. Neste artigo, examinamos, nos 30 anos da Nova República, tanto no plano discursivo, quanto no plano das práticas, como a reflexão sobre o ensino de língua portuguesa como língua materna no Brasil operou com a história linguística do Brasil, com a historicidade do português brasileiro e, de forma mais específica, com a questão da mudança linguística. Para tal, analisamos os Parâmetros Curriculares Nacionais para o Ensino Médio (2000), os PCN+ Ensino Médio: Orientações Educacionais Complementares aos Parâmetros Curriculares Nacionais (2002), as Orientações Curriculares para o Ensino Médio (2006) e a Base Nacional Comum Curricular (2018). A seguir, recuamos ao momento imediatamente anterior ao da promulgação da Constituição, considerando ainda as Diretrizes para o aperfeiçoamento do ensino/aprendizagem da língua portuguesa (1986). Contemplados os discursos, seguimos para as práticas, analisando quais componentes curriculares referentes à Linguística Histórica e à História da Língua Portuguesa integram as grades curriculares dos cursos de Graduação em Letras das universidades vinculadas ao Projeto Nacional “Para a História do Português Brasileiro” (PHPB) e ainda as ementas e programas desses componentes curriculares, com o objetivo de delinear um quadro aproximativo do que tem norteado a formação dos professores nas universidades em que há grupos de pesquisa dedicados à história do português brasileiro.

    وصف الملف: application/pdf

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    دورية أكاديمية

    المساهمون: National Cancer Institute

    المصدر: BJUI Compass ; volume 3, issue 3, page 226-237 ; ISSN 2688-4526 2688-4526

    الوصف: Objectives In a prospective, comparative effectiveness study, we assessed clinical and psychological factors associated with switching from active surveillance (AS) to active treatment (AT) among low‐risk prostate cancer (PCa) patients. Methods Using ultra‐rapid case identification, we conducted pretreatment telephone interviews ( N = 1139) with low‐risk patients (PSA ≤ 10, Gleason≤6) and follow‐up interviews 6–10 months post‐diagnosis ( N = 1057). Among men remaining on AS for at least 12 months ( N = 601), we compared those who continued on AS ( N = 515) versus men who underwent delayed AT ( N = 86) between 13 and 24 months, using Cox proportional hazards models. Results Delayed AT was predicted by time dependent PSA levels (≥10 vs. <10; HR = 5.6, 95% CI 2.4–13.1) and Gleason scores (≥7 vs. ≤6; adjusted HR = 20.2, 95% CI 12.2–33.4). Further, delayed AT was more likely among men whose urologist initially recommended AT (HR = 2.13, 95% CI 1.07–4.22), for whom tumour removal was very important (HR = 2.18, 95% CI 1.35–3.52), and who reported greater worry about not detecting disease progression early (HR = 1.67, 1.05–2.65). In exploratory analyses, 31% (27/86) switched to AT without evidence of progression, while 4.7% (24/515) remained on AS with evidence of progression. Conclusions After adjusting for clinical evidence of disease progression over the first year post‐diagnosis, we found that urologists' initial treatment recommendation and patients' early treatment preferences and concerns about AS each independently predicted undergoing delayed AT during the second year post‐diagnosis. These findings, along with almost one‐half undergoing delayed AT without evidence of progression, suggest the need for greater decision support to remain on AS when it is clinically indicated.

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