المؤلفون: Paes Dias, Mariana, Tripathi, Vivek, van der Heijden, Ingrid, Cong, Ke, Manolika, Eleni-Maria, Bhin, Jinhyuk, Gogola, Ewa, Galanos, Panagiotis, Annunziato, Stefano, Lieftink, Cor, Andújar-Sánchez, Miguel, Chakrabarty, Sanjiban, Smith, Graeme C M, van de Ven, Marieke, Beijersbergen, Roderick L, Bartkova, Jirina, Rottenberg, Sven, Cantor, Sharon, Bartek, Jiri, Ray Chaudhuri, Arnab, Jonkers, Jos

المساهمون: Molecular, Cell and Cancer Biology

المصدر: Molecular cell ; 81 ; 22 ; 4692 ; 4708.e9 ; United States

مصطلحات موضوعية: 53BP1, BRCA1, DNA damage response, DNA ligase III, PARP1, PARP inhibitor, drug resistance, replication fork, ssDNA gaps, vulnerabilities

العلاقة: Molecular Cell; https://doi.org/10.1016/j.molcel.2021.09.005Test; Paes Dias M, Tripathi V, van der Heijden I, Cong K, Manolika EM, Bhin J, Gogola E, Galanos P, Annunziato S, Lieftink C, Andújar-Sánchez M, Chakrabarty S, Smith GCM, van de Ven M, Beijersbergen RL, Bartkova J, Rottenberg S, Cantor S, Bartek J, Ray Chaudhuri A, Jonkers J. Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps. Mol Cell. 2021 Nov 18;81(22):4692-4708.e9. doi:10.1016/j.molcel.2021.09.005. Epub 2021 Sep 22. PMID: 34555355; PMCID: PMC9098260.; http://hdl.handle.net/20.500.14038/51873Test

الإتاحة: https://doi.org/10.1016/j.molcel.2021.09.005Test
https://doi.org/20.500.14038/51873Test
https://hdl.handle.net/20.500.14038/51873Test

المؤلفون: Palit, Sander A.L., Vis, Daniel, Stelloo, Suzan, Lieftink, Cor, Prekovic, Stefan, Bekers, Elise, Hofland, Ingrid, Šuštić, Tonći, Wolters, Liesanne, Beijersbergen, Roderick, Bergman, Andries M., Győrffy, Balázs, Wessels, Lodewyk F.A., Zwart, Wilbert, van der Heijden, Michiel S.

المصدر: Palit , S A L , Vis , D , Stelloo , S , Lieftink , C , Prekovic , S , Bekers , E , Hofland , I , Šuštić , T , Wolters , L , Beijersbergen , R , Bergman , A M , Győrffy , B , Wessels , L F A , Zwart , W & van der Heijden , M S 2019 , ' TLE3 loss confers AR inhibitor resistance by facilitating GR-mediated human prostate cancer cell growth ' , eLife , vol. 8 , e47430 . https://doi.org/10.7554/eLife.47430Test

مصطلحات موضوعية: AR, CRISPR-Cas9 screen, Drug resistance, Enzalutamide, GR, Prostate cancer, TLE3, Androgen Receptor Antagonists/pharmacology, Humans, Male, Gene Expression Regulation, Neoplastic/drug effects, Prostate/metabolism, Hepatocyte Nuclear Factor 3-alpha/genetics, Phenylthiohydantoin/analogs & derivatives, CRISPR-Cas Systems/genetics, Receptors, Androgen/genetics, Neoplasm/genetics, HEK293 Cells, Cell Line, Tumor, Transcriptional Activation/drug effects, Prostatic Neoplasms/drug therapy, Glucocorticoid/genetics, Cell Proliferation/drug effects, Co-Repressor Proteins/genetics, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

العلاقة: https://research.tue.nl/en/publications/9e1e0d8b-0968-4afb-ad29-65c3fbed657fTest

الإتاحة: https://doi.org/10.7554/eLife.47430Test
https://research.tue.nl/en/publications/9e1e0d8b-0968-4afb-ad29-65c3fbed657fTest
http://www.scopus.com/inward/record.url?scp=85077548136&partnerID=8YFLogxKTest

المؤلفون: Tuijnenburg, Paul, aan de Kerk, Daan J., Jansen, Machiel H., Morris, Ben, Lieftink, Cor, Beijersbergen, Roderick L., van Leeuwen, Ester M.M., Kuijpers, Taco W.

المصدر: European Journal of Immunology ; volume 50, issue 1, page 73-85 ; ISSN 0014-2980 1521-4141

الإتاحة: https://doi.org/10.1002/eji.201948241Test

المؤلفون: Buikhuisen, Joyce Y., Gomez Barila, Patricia M., Cameron, Kate, Suijkerbuijk, Saskia J. E., Lieftink, Cor, di Franco, Simone, Krotenberg Garcia, Ana, Uceda Castro, Rebeca, Lenos, Kristiaan J., Nijman, Lisanne E., Torang, Arezo, Longobardi, Ciro, de Jong, Joan H., Dekker, Daniëlle, Stassi, Giorgio, Vermeulen, Louis, Beijersbergen, Roderick L., van Rheenen, Jacco, Huveneers, Stephan, Medema, Jan Paul

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f572fd54fecc4c30ee7657d99d8f751Test

المؤلفون: Hoefsmit, Esmee, Royen, Paula van, Rao, Disha, Stunnenberg, Johanna, Dimitriadis, Petros, Lieftink, Cor, Morris, Ben, Rozeman, Elisa, Reijers, Irene, Lacroix, Ruben, Shehwana, Huma, Ligtenberg, Maarten, Beijersbergen, Roderick, Peeper, Daniel, Blank, Christian

المصدر: Regular and Young Investigator Award Abstracts

الإتاحة: https://doi.org/10.1136/jitc-2022-sitc2022.0979Test

المؤلفون: Matlung, Hanke L, Babes, Liane, Zhao, Xi Wen, van Houdt, Michel, Treffers, Louise W, van Rees, Dieke J, Franke, Katka, Schornagel, Karin, Verkuijlen, Paul, Janssen, Hans, Halonen, Pasi, Lieftink, Cor, Beijersbergen, Roderick L, Leusen, Jeanette H W, Boelens, Jaap J, Kuhnle, Ingrid, van der Werff Ten Bosch, Jutte, Seeger, Karl, Rutella, Sergio, Pagliara, Daria, Matozaki, Takashi, Suzuki, Eiji, Menke-van der Houven van Oordt, Catharina Willemien, van Bruggen, Robin, Roos, Dirk, van Lier, Rene A W, Kuijpers, Taco W, Kubes, Paul, van den Berg, Timo K

المصدر: Matlung , H L , Babes , L , Zhao , X W , van Houdt , M , Treffers , L W , van Rees , D J , Franke , K , Schornagel , K , Verkuijlen , P , Janssen , H , Halonen , P , Lieftink , C , Beijersbergen , R L , Leusen , J H W , Boelens , J J , Kuhnle , I , van der Werff Ten Bosch , J , Seeger , K , Rutella , S , Pagliara , D , Matozaki , T , Suzuki ....

العلاقة: https://research.vumc.nl/en/publications/e4bd178b-df0c-49bf-a0ef-59ea39285a41Test

الإتاحة: https://doi.org/10.1016/j.celrep.2018.05.082Test
https://research.vumc.nl/en/publications/e4bd178b-df0c-49bf-a0ef-59ea39285a41Test

المؤلفون: Šuštić, Tonći, van Wageningen, Sake, Bosdriesz, Evert, Reid, Robert J D, Dittmar, John, Lieftink, Cor, Beijersbergen, Roderick L, Wessels, Lodewyk F A, Rothstein, Rodney, Bernards, René

المصدر: Šuštić , T , van Wageningen , S , Bosdriesz , E , Reid , R J D , Dittmar , J , Lieftink , C , Beijersbergen , R L , Wessels , L F A , Rothstein , R & Bernards , R 2018 , ' A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers ' , Genome Medicine , vol. 10 , no. 1 , 90 , pp. 90 . https://doi.org/10.1186/s13073-018-0600-zTest

مصطلحات موضوعية: Antineoplastic Agents/pharmacology, Benzimidazoles/pharmacology, Cell Line, Tumor, Colonic Neoplasms/drug therapy, Endoplasmic Reticulum Stress, Endoribonucleases/genetics, HEK293 Cells, Humans, MAP Kinase Kinase Kinases/antagonists & inhibitors, Protein Kinase Inhibitors/pharmacology, Protein-Serine-Threonine Kinases/genetics, Proto-Oncogene Proteins c-jun/genetics, Proto-Oncogene Proteins p21(ras)/genetics, Pyridones/pharmacology, Pyrimidinones/pharmacology, Unfolded Protein Response, Yeasts/genetics, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

العلاقة: https://research.vu.nl/en/publications/81f28fe1-8e98-46c2-b48a-ecb93db7aac0Test

الإتاحة: https://doi.org/10.1186/s13073-018-0600-zTest
https://research.vu.nl/en/publications/81f28fe1-8e98-46c2-b48a-ecb93db7aac0Test
https://hdl.handle.net/1871.1/81f28fe1-8e98-46c2-b48a-ecb93db7aac0Test
http://www.scopus.com/inward/record.url?scp=85057273107&partnerID=8YFLogxKTest
http://www.scopus.com/inward/citedby.url?scp=85057273107&partnerID=8YFLogxKTest

المؤلفون: Matlung, Hanke L., Babes, Liane, Zhao, Xi Wen, van Houdt, Michel, Treffers, Louise W., van Rees, Dieke J., Franke, Katka, Schornagel, Karin, Verkuijlen, Paul, Janssen, Hans, Halonen, Pasi, Lieftink, Cor, Beijersbergen, Roderick L., Leusen, Jeanette H.W., Boelens, Jaap J., Kuhnle, Ingrid, van der Werff Ten Bosch, Jutte, Seeger, Karl, Rutella, Sergio, Pagliara, Daria, Matozaki, Takashi, Suzuki, Eiji, Menke-van der Houven van Oordt, Catharina Willemien, van Bruggen, Robin, Roos, Dirk, van Lier, Rene A.W., Kuijpers, Taco W., Kubes, Paul, van den Berg, Timo K.

المساهمون: CTI Leusen, Infection & Immunity, PMC Medisch specialisten, CTI Nierkens

مصطلحات موضوعية: Animals, Antibodies, Monoclonal/therapeutic use, Antibody-Dependent Cell Cytotoxicity, CD11b Antigen/metabolism, CD18 Antigens/metabolism, CD47 Antigen/metabolism, Cell Line, Tumor, Female, Humans, Male, Melanoma, Experimental/metabolism, Mice, Inbred C57BL, Neoplasms/drug therapy, Neutrophils/immunology, Receptors, IgG/metabolism, Immunologic/genetics, Transplantation, Homologous, General Biochemistry,Genetics and Molecular Biology, Journal Article, Research Support, Non-U.S. Gov't

وصف الملف: image/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/371497Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/371497Test

المؤلفون: Berns, Katrien, Caumanns, Joseph J, Hijmans, E Marielle, Gennissen, Annemiek M C, Severson, Tesa M, Evers, Bastiaan, Wisman, G Bea A, Jan Meersma, Gert, Lieftink, Cor, Beijersbergen, Roderick L, Itamochi, Hiroaki, van der Zee, Ate G J, de Jong, Steven, Bernards, René

المصدر: Berns , K , Caumanns , J J , Hijmans , E M , Gennissen , A M C , Severson , T M , Evers , B , Wisman , G B A , Jan Meersma , G , Lieftink , C , Beijersbergen , R L , Itamochi , H , van der Zee , A G J , de Jong , S & Bernards , R 2018 , ' ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors ' , ONCOGENE , vol. 37 , no. 33 , pp. 4611-4625 . https://doi.org/10.1038/s41388-018-0300-6Test

مصطلحات موضوعية: COLON-CANCER, RESISTANCE, ACTIVATION, LANDSCAPE, MYC

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/d6dde233-b4b8-4c28-b6ee-8b5dd1534889Test

الإتاحة: https://doi.org/10.1038/s41388-018-0300-6Test
https://hdl.handle.net/11370/d6dde233-b4b8-4c28-b6ee-8b5dd1534889Test
https://research.rug.nl/en/publications/d6dde233-b4b8-4c28-b6ee-8b5dd1534889Test
https://pure.rug.nl/ws/files/64337253/ARID1A_mutation_sensitizes_most_ovarian_clear_cell_carcinomas_to_BET_inhibitors.pdfTest

المؤلفون: Wang, Cun, Jin, Haojie, Gao, Dongmei, Wang, Liqin, Evers, Bastiaan, Xue, Zheng, Jin, Guangzhi, Lieftink, Cor, Beijersbergen, Roderick L., Qin, Wenxin, Bernards, René

المصدر: Cell Research ; volume 28, issue 6, page 690-692 ; ISSN 1001-0602 1748-7838

مصطلحات موضوعية: Cell Biology, Molecular Biology

الإتاحة: https://doi.org/10.1038/s41422-018-0020-zTest
http://www.nature.com/articles/s41422-018-0020-zTest
http://www.nature.com/articles/s41422-018-0020-z.pdfTest