المؤلفون: Yu, Xiaoxiang, Shao, Zeling, Li, Zhiguo

مصطلحات موضوعية: Mathematics - Combinatorics, 05C10

الوصف: The \emph{matching book thickness} $mbt(G)$ of $G$ is the minimum integer $m$ such that an $m$-page matching book embedding exists. A graph $G$ is called \emph{dispersable} if $mbt(G)=\Delta(G)$, \emph{nearly dispersable} if $mbt(G)=\Delta(G)+1$. Recently, the authors determined the nearly dispersability of odd toroidal grids $T_{s,t}$. In this note, we further present a brief proof for this result.

الوصول الحر: http://arxiv.org/abs/2406.00585Test

المؤلفون: Shao, Zeling, Yu, Xiaoxiang, Li, Zhiguo

مصطلحات موضوعية: Mathematics - Combinatorics, 05C10

الوصف: In this paper, the dispersability of the Cartesian graph bundle over two cycles is completely solved. We show the Cartesian graph bundle $G$ over two cycles is dispersable if $G$ is bipartite; otherwise, $G$ is nearly dispersable.
Comment: arXiv admin note: text overlap with arXiv:2310.06612

الوصول الحر: http://arxiv.org/abs/2405.16253Test

المؤلفون: Ning, Li, Li, Zhiguo, Wei, Dianjun, Chen, Haiyan, Yang, Chao, Wu, Dawei, Wang, Yanchun, Zhang, Jingwei

المصدر: Brazilian Journal of Medical and Biological Research. January 2018 51(4)

مصطلحات موضوعية: Contrast-induced acute kidney injury, Percutaneous coronary intervention, Semaphorin 3A, Neutrophil gelatinase-associated lipocalin, Biomarker

الوصف: Contrast-induced acute kidney injury (CI-AKI) is a serious complication of diagnostic coronary angiograph and percutaneous coronary intervention (PCI). However, the exact pathophysiological mechanisms underlying CI-AKI development are largely unknown. The present study examined whether urinary semaphorin 3A levels predict the development of CI-AKI in patients undergoing PCI. This study enrolled 168 patients with stable angina undergoing elective PCI. Serial urine samples, obtained at baseline and 2, 6, 12, 24, 36, and 48 h post-PCI were analyzed by semaphorin 3A and neutrophil gelatinase-associated lipocalin (NGAL) ELISA kit. AKI was defined as an increase in serum creatinine beyond 50% according to the RIFLE classification system. Receiver operator characteristic (ROC) curve analyses identified optimal semaphorin 3A and NGAL values for diagnosing CI-AKI. CI-AKI occurred in 20 of 168 patients. There were no significant differences in the baseline clinical characteristics and angiographic findings between non-AKI patients group and AKI patients group. Both urinary semaphorin 3A and NGAL levels significantly increased at 2 and 6 h post-PCI. ROC analysis showed that the cut-off value of 389.5 pg/mg semaphorin 3A at 2 h post-PCI corresponds to 94% sensitivity and 75% specificity and the cut-off value of 94.4 ng/mg NGAL at 2 h post-PCI corresponds to 74% sensitivity and 82% specificity. Logistic regression showed that semaphorin 3A levels at 2 and 6 h post-PCI were the significant predictors of AKI in our cohort. Urinary semaphorin 3A may be a promising early biomarker for predicting CI-AKI in patients undergoing PCI.

وصف الملف: text/html

الوصول الحر: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000400618Test

المؤلفون: Nie, Hongyi, Liu, Xiaoyan, Pan, Jiao, Li, Wenfeng, Li, Zhiguo, Zhang, Shaowu, Chen, Shenglu, Miao, Xiaoqing, Zheng, Nenggan, Su, Songkun

المصدر: Genetics and Molecular Biology. December 2017 40(4)

مصطلحات موضوعية: honeybee, royal jelly production, gene chip, molecular marker, differentially expressed genes

الوصف: China is the largest royal jelly producer and exporter in the world, and high royal jelly-yielding strains have been bred in the country for approximately three decades. However, information on the molecular mechanism underlying high royal jelly production is scarce. Here, a cDNA microarray was used to screen and identify differentially expressed genes (DEGs) to obtain an overview on the changes in gene expression levels between high and low royal jelly producing bees. We developed a honey bee gene chip that covered 11,689 genes, and this chip was hybridised with cDNA generated from RNA isolated from heads of nursing bees. A total of 369 DEGs were identified between high and low royal jelly producing bees. Amongst these DEGs, 201 (54.47%) genes were up-regulated, whereas 168 (45.53%) were down-regulated in high royal jelly-yielding bees. Gene ontology (GO) analyses showed that they are mainly involved in four key biological processes, and pathway analyses revealed that they belong to a total of 46 biological pathways. These results provide a genetic basis for further studies on the molecular mechanisms involved in high royal jelly production.

وصف الملف: text/html

الوصول الحر: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000500781Test

المؤلفون: Yu, Xiaoxiang, Shao, Zeling, Li, Zhiguo

مصطلحات موضوعية: Mathematics - Combinatorics, 05C10

الوصف: In this paper, we give the classification of circulant graphs $C(\mathbb{Z}_{n},S)$ with $|S|=2$ and completely solve the dispersability of circulant graphs $C(\mathbb{Z}_{n},\{1, k\})$.

الوصول الحر: http://arxiv.org/abs/2310.06612Test

المؤلفون: Qiu, Nemin, Li, Zhiguo, Li, Yuan, Zhu, Chuang

مصطلحات موضوعية: Computer Science - Computer Vision and Pattern Recognition

الوصف: The high biological properties and low energy consumption of Spiking Neural Networks (SNNs) have brought much attention in recent years. However, the converted SNNs generally need large time steps to achieve satisfactory performance, which will result in high inference latency and computational resources increase. In this work, we propose a highly efficient and fast SNN for object detection. First, we build an initial compact ANN by using quantization training method of convolution layer fold batch normalization layer and neural network modification. Second, we theoretically analyze how to obtain the low complexity SNN correctly. Then, we propose a scale-aware pseudoquantization scheme to guarantee the correctness of the compact ANN to SNN. Third, we propose a continuous inference scheme by using a Feed-Forward Integrate-and-Fire (FewdIF) neuron to realize high-speed object detection. Experimental results show that our efficient SNN can achieve 118X speedup on GPU with only 1.5MB parameters for object detection tasks. We further verify our SNN on FPGA platform and the proposed model can achieve 800+FPS object detection with extremely low latency.

الوصول الحر: http://arxiv.org/abs/2309.15883Test

المؤلفون: Song, Rui, Luo, Shikai, Zeng, Donglin, Zhang, Hao Helen, Lu, Wenbin, Li, Zhiguo

مرشدي الرسالة: Univ Arizona, Dept Math

مصطلحات موضوعية: Personalized medicine, single index model, semi-parametric inference

الوصف: Different from the standard treatment discovery framework which is used for finding single treatments for a homogenous group of patients, personalized medicine involves finding therapies that are tailored to each individual in a heterogeneous group. In this paper, we propose a new semiparametric additive single-index model for estimating individualized treatment strategy. The model assumes a flexible and nonparametric link function for the interaction between treatment and predictive covariates. We estimate the rule via monotone B-splines and establish the asymptotic properties of the estimators. Both simulations and an real data application demonstrate that the proposed method has a competitive performance.

العلاقة: http://projecteuclid.org/euclid.ejs/1486976416Test

الإتاحة: http://hdl.handle.net/10150/625783Test
http://arizona.openrepository.com/arizona/handle/10150/625783Test

المؤلفون: WANG Yafei, GENG Tianxiang, CHEN Linlin, LI Zhiguo, LI Shipeng

المصدر: Zhongliu Fangzhi Yanjiu, Vol 50, Iss 11, Pp 1059-1065 (2023)

مصطلحات موضوعية: mir-524-5p, heg1 protein, esophageal cancer, epithelial-mesenchymal transition, invasion, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

الوصف: Objective To investigate the mechanism and the effect of miR-524-5p regulating HEG1 expression on the proliferation and epithelial-mesenchymal transition of esophageal cancer cells. Methods The expression levels of miR-524-5p and HEG1 mRNA in esophageal cancer cells and normal esophageal epithelial cells were detected by qRT-PCR. KYSE30 cells were divided into miR-524-5p mimic group, miR-524-5p NC group, miR-524-5p mimic+pcDNA3.1 group, and miR-524-5p mimic+pcDNA3.1-HEG1 group. Non-transfected cells were set as the normal control group (group Control). CCK-8 method was applied to detect the proliferation ability of KYSE30 cells. Western blot analysis was conducted to detect the expression of proteins related to EMT, invasion, and migration and the HEG1 protein. Scratch and Transwell assays were applied to detect the migration and invasion abilities of KYSE30 cells. A dual-luciferase reporter gene was used to examine the targeting relationship between miR-524-5p and HEG1. Results miR-524-5p was lowly expressed in four esophageal cancer cell lines, namely, TE-1, KYSE30, KYSE150, and NEC (P < 0.05). KYSE30 cells with the lowest expression level were selected for subsequent experiments. HEG1 mRNA was highly expressed in four esophageal cancer cell lines (P < 0.05). The GEPIA database showed that HEG1 was highly expressed in esophageal cancer tumor tissues (P < 0.05). KYSE30 cells in the miR-524-5p mimic group had lower proliferation ability, colony formation number, mesenchymal marker protein expression, and migration and invasion abilities and upregulated epithelial marker protein E-cadherin level than cells in the miR-524-5p NC group (P < 0.05). The miR-524-5p mimic+pcDNA3.1-HEG1 group significantly reversed the inhibitory effect of overexpression of miR-524-5p on the proliferation, epithelial–mesenchymal transformation, invasion, and metastasis of KYSE30 cells (P < 0.05). The luciferase activity of cells in the miR-524-5p mimic and WT-HEG1 co-transfection groups was lower than that in the miR-524-5p NC and WT-HEG1 co-transfection groups (P < 0.05). Conclusion miR-524-5p is lowly expressed in EC cells and tissues. The overexpression of miR-524-5p can negatively regulate the expression of HEG1 in esophageal cancer cell line (KYSE30 cells) and reduce the proliferation, EMT process, and invasion and migration abilities of KYSE30 cells.

وصف الملف: electronic resource

العلاقة: http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2023.23.0426Test; https://doaj.org/toc/1000-8578Test

الوصول الحر: https://doaj.org/article/80b293be82194d4eae4afaadd711bdb5Test

المؤلفون: Li, Zhiguo, Ye, Qing, Shao, Zeling

مصطلحات موضوعية: Mathematics - Combinatorics, 05C15

الوصف: The Alon-Tarsi number of a graph $G$ is the smallest $k$ for which there is an orientation $D$ of $G$ with max outdegree $k-1$ such that the number of Eulerian subgraphs of $G$ with an even number of edges differs from the number of Eulerian subgraphs with an odd number of edges. In this paper, we obtain the Alon-Tarsi number of a Halin graph equals 4 when it is a wheel of even order and 3 otherwise.

الوصول الحر: http://arxiv.org/abs/2110.11617Test

المؤلفون: Shao, Zeling, Liu, Yanqing, Li, Zhiguo

مصطلحات موضوعية: Mathematics - Combinatorics, 05C10

الوصف: The book embedding of a graph $G$ is to place the vertices of $G$ on the spine and draw the edges to the pages so that the edges in the same page do not cross with each other. A book embedding is matching if the vertices in the same page have maximum degree at most 1. The matching book thickness is the minimum number of pages in which a graph can be matching book embedded. A graph $G$ is dispersable if and only if $mbt(G)=\Delta(G)$. In this paper, we prove that bipartite cubic planar graphs are dispersable.

الوصول الحر: http://arxiv.org/abs/2107.00907Test