نتائج البحث

21

LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

المؤلفون: Peng Zhao, Yuanzhong Xu, Lu-Lin Jiang, Xuejun Fan, Zhiqiang Ku, Leike Li, Xiaoye Liu, Mi Deng, Hisashi Arase, Jay-Jiguang Zhu, Timothy Y. Huang, Yingjun Zhao, Chengcheng Zhang, Huaxi Xu, Qingchun Tong, Ningyan Zhang, Zhiqiang An

المصدر: Molecular neurodegeneration. 17(1)

مصطلحات موضوعية: Membrane Glycoproteins, Induced Pluripotent Stem Cells, Brain, Plaque, Amyloid, Ligands, Cellular and Molecular Neuroscience, Mice, Alzheimer Disease, Animals, Humans, Neurology (clinical), Microglia, Receptors, Immunologic, Molecular Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337ce753117af8b6e62f55546ade4f01Test
https://pubmed.ncbi.nlm.nih.gov/35717259Test

22

Author response: Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment

المؤلفون: Chun Geun Lee, Ningyan Zhang, Zhiqiang An, Yankai Wen, Xun Gui, Jongmin Jeong, Constance L. Atkins, Dechun Feng, Bin Gao, William M. Lee, Nicolas F. Moreno, Jack A. Elias, Zhao Shan, Fong Wilson Lam, Leike Li, Cynthia Ju, Meng Wang

مصطلحات موضوعية: CHITINASE 3-LIKE 1, Liver injury, business.industry, medicine, Platelet, Pharmacology, business, medicine.disease, Acetaminophen, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0a6003c466c48bd4e908838c406b8572Test
https://doi.org/10.7554/elife.68571.sa2Test

23

Potent Bispecific Neutralizing Antibody Targeting Glycoprotein B and the gH/gL/pUL128/130/131 Complex of Human Cytomegalovirus

المؤلفون: Hang Su, Zhiqiang An, Ningyan Zhang, Leike Li, Dai Wang, Weifeng Xu, Diana Montgomery, Wei Xiong, Xinli Liu, Peng Gao, Amy S. Espeseth, Xiaohua Ye, Tong-Ming Fu, Ningning Ma, Daniel C. Freed, Zhiqiang Ku

المصدر: Antimicrobial Agents and Chemotherapy

مصطلحات موضوعية: Human cytomegalovirus, gB, medicine.drug_class, Pentamer, viruses, Cytomegalovirus, Antibodies, Viral, Monoclonal antibody, Antiviral Agents, Neutralization, 03 medical and health sciences, Cricetulus, pentamer, Viral Envelope Proteins, Antigen, Cricetinae, medicine, Animals, Humans, Pharmacology (medical), Neutralizing antibody, Glycoproteins, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, 0303 health sciences, biology, 030306 microbiology, virus diseases, neutralizing antibody, medicine.disease, Antibodies, Neutralizing, Macaca mulatta, IgG-scFv, Virology, bispecific antibody, Infectious Diseases, chemistry, monoclonal antibody, human cytomegalovirus, Cytomegalovirus Infections, biology.protein, Antibody, Glycoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3625dddaa506e1b810644a29fc7fd28Test
https://doi.org/10.1128/aac.02422-20Test

24

A conditionally replication-defective cytomegalovirus vaccine elicits potent and diverse functional monoclonal antibodies in a phase I clinical trial

المؤلفون: Ningyan Zhang, Tong-Ming Fu, Fengsheng Li, Xiaohua Ye, Zhiqiang An, Diane F. Barrett, Leike Li, Daniel C. Freed, Stuart P. Adler, Wei Xiong, Richard E. Rupp, Dai Wang, Yaping Liu

المصدر: NPJ Vaccines
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e1720ce82235afd4b4281f3bfdedb2Test
https://pubmed.ncbi.nlm.nih.gov/34078915Test

25

Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step

المؤلفون: Zhiqiang Ku, Ningyan Zhang, Jason S. McLellan, Hang Su, Leike Li, Wei Xiong, Zhiqiang An, Tong-Ming Fu, Hua Zhu, Dabbu Kumar Jaijyan, Xiaohua Ye, Zihao Yuan, Fengsheng Li, Daniel Wrapp, Aimin Tang, Dai Wang, Daniel C. Freed

المصدر: PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 8, p e1008736 (2020)

مصطلحات موضوعية: Human cytomegalovirus, Cytomegalovirus Infection, Viral Diseases, Physiology, viruses, Amino Acid Motifs, Cytomegalovirus, Antibodies, Viral, Pathology and Laboratory Medicine, Biochemistry, Epitope, Virions, Epitopes, Binding Analysis, Medical Conditions, Viral Envelope Proteins, Immune Physiology, Medicine and Health Sciences, Biology (General), Enzyme-Linked Immunoassays, Neutralizing antibody, Conserved Sequence, 0303 health sciences, Immune System Proteins, biology, Chemistry, 030302 biochemistry & molecular biology, Infectious Diseases, Medical Microbiology, Viral Pathogens, Cytomegalovirus Infections, Viruses, Human Cytomegalovirus, Antibody, Pathogens, Cell Binding Assay, Research Article, Herpesviruses, Viral Entry, medicine.drug_class, QH301-705.5, Immunology, Viral Structure, Monoclonal antibody, Research and Analysis Methods, Microbiology, Antibodies, 03 medical and health sciences, Antigen, Viral entry, Virology, Genetics, medicine, Humans, Immunoassays, Molecular Biology, Microbial Pathogens, Chemical Characterization, 030304 developmental biology, Linear epitope, Organisms, Biology and Life Sciences, Proteins, RC581-607, Virus Internalization, medicine.disease, Antibodies, Neutralizing, biology.protein, Immunologic Techniques, Parasitology, Immunologic diseases. Allergy, DNA viruses, Viral Transmission and Infection

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b61997ac4fa0b0e55f0f3693859ae5Test
https://pubmed.ncbi.nlm.nih.gov/32745149Test

26

A Replication-Defective Human Cytomegalovirus Vaccine Elicits Humoral Immune Responses Analogous to Those with Natural Infection

المصدر: J Virol

مصطلحات موضوعية: Adult, Male, Human cytomegalovirus, viruses, Immunology, Cytomegalovirus, Priming (immunology), Biology, Antibodies, Viral, Virus Replication, Microbiology, Neutralization, Cell Line, Cytomegalovirus Vaccines, Young Adult, 03 medical and health sciences, Immune system, Double-Blind Method, Virology, Vaccines and Antiviral Agents, medicine, Humans, Antigens, Viral, Aged, 030304 developmental biology, Immunity, Cellular, 0303 health sciences, Pregnancy, 030306 microbiology, Vaccination, Middle Aged, biochemical phenomena, metabolism, and nutrition, medicine.disease, Antibodies, Neutralizing, Infectious Disease Transmission, Vertical, United States, Immunity, Humoral, Insect Science, Cytomegalovirus Infections, Humoral immunity, biology.protein, Female, Immunization, Antibody

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62814b3b6ae29029963eece5e4456f06Test
https://doi.org/10.1128/jvi.00747-19Test

27

Active evolution of memory B-cells specific to viral gH/gL/pUL128/130/131 pentameric complex in healthy subjects with silent human cytomegalovirus infection

المصدر: Oncotarget

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ea6d4b43a3726779a99964843c467bTest
https://doi.org/10.18632/oncotarget.18359Test

28

Identification of adipocyte plasma membrane-associated protein as a novel modulator of human cytomegalovirus infection

المؤلفون: Yuanzhi Chen, Leike Li, Hua Zhu, Wei Xiong, Amy S. Espeseth, Daniel C. Freed, Xuejun Fan, Tong-Ming Fu, Ningyan Zhang, Xun Gui, John W. Loughney, Richard R. Rustandi, Zhiqiang Ku, Ningning Ma, Jian Liu, Xiaohua Ye, Dai Wang, Hang Su, Zhiqiang An, Xi He

المصدر: PLoS Pathogens, Vol 15, Iss 7, p e1007914 (2019)
PLoS Pathogens

مصطلحات موضوعية: Human cytomegalovirus, Cytomegalovirus Infection, Viral Diseases, Physiology, viruses, Cell Membranes, Cytomegalovirus, Pathology and Laboratory Medicine, Biochemistry, Madin Darby Canine Kidney Cells, Gene Knockout Techniques, Mice, Immune Physiology, Medicine and Health Sciences, Adipocytes, Biology (General), Pathogen, chemistry.chemical_classification, Staining, 0303 health sciences, Gene knockdown, Immune System Proteins, Membrane Glycoproteins, Virulence, 030302 biochemistry & molecular biology, Cell Staining, virus diseases, Recombinant Proteins, medicine.anatomical_structure, Infectious Diseases, Medical Microbiology, Viral Pathogens, Viruses, Cytomegalovirus Infections, Human Cytomegalovirus, Antibody, Pathogens, Cellular Structures and Organelles, Research Article, Cell type, Herpesviruses, Infectious Disease Control, Imaging Techniques, QH301-705.5, Immunology, Biology, Research and Analysis Methods, Microbiology, 3T3 cells, Antibodies, 03 medical and health sciences, Dogs, Virology, Fluorescence Imaging, Genetics, medicine, Animals, Humans, Molecular Biology, Microbial Pathogens, 030304 developmental biology, Viral Structural Proteins, Biology and life sciences, Host Microbial Interactions, Cell Membrane, Organisms, Membrane Proteins, Proteins, Epithelial Cells, Cell Biology, Fibroblasts, Virus Internalization, biochemical phenomena, metabolism, and nutrition, RC581-607, medicine.disease, Vector-Borne Diseases, chemistry, Specimen Preparation and Treatment, biology.protein, NIH 3T3 Cells, Parasitology, Ectopic expression, Immunologic diseases. Allergy, Glycoprotein, DNA viruses

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11fddbeab25d9164dfc36ba78facd57Test
https://doaj.org/article/d40c00584c8f4c79b960c79243f197f9Test

29

Potent neutralizing antibodies elicited by dengue vaccine in rhesus macaque target diverse epitopes

المؤلفون: Georgina To'a Salazar, Elizabeth Thoryk, Danilo R. Casimiro, Qihui Wang, Benjamin J. Doranz, Weixu Meng, Daniel R. DiStefano, Kalpit A. Vora, Andrew J. Bett, Trevor Barnes, Jennifer M. Pfaff, Ningyan Zhang, Leike Li, Zhiqiang An, Melanie Horton

المصدر: PLoS Pathogens, Vol 15, Iss 6, p e1007716 (2019)
PLoS Pathogens

مصطلحات موضوعية: RNA viruses, Physiology, Monkeys, Dengue virus, Pathology and Laboratory Medicine, Antibodies, Viral, medicine.disease_cause, Biochemistry, Epitope, Dengue fever, Epitopes, Immune Physiology, Medicine and Health Sciences, Enzyme-Linked Immunoassays, Biology (General), Neutralizing antibody, Mammals, Vaccines, 0303 health sciences, Immune System Proteins, biology, Viral Vaccine, 030302 biochemistry & molecular biology, Eukaryota, Antibodies, Monoclonal, Animal Models, Vaccination, Infectious Diseases, Experimental Organism Systems, Medical Microbiology, Viral Pathogens, Viruses, Vertebrates, Pathogens, Antibody, Immunoglobulin Heavy Chains, West Nile virus, Macaque, Research Article, Primates, Infectious Disease Control, QH301-705.5, Immunology, Dengue Vaccines, Research and Analysis Methods, Microbiology, Antibodies, 03 medical and health sciences, Virology, Old World monkeys, Genetics, medicine, Animals, Immunoassays, Molecular Biology Techniques, Microbial Pathogens, Molecular Biology, Dengue vaccine, 030304 developmental biology, Flaviviruses, Rhesus Monkeys, Organisms, Biology and Life Sciences, Proteins, Dengue Virus, RC581-607, medicine.disease, Antibodies, Neutralizing, Macaca mulatta, Amniotes, Immunologic Techniques, Animal Studies, biology.protein, Immunoglobulin Light Chains, Parasitology, Immunologic diseases. Allergy, Cloning, Molecular Cloning

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb900071e4b986e0433c492a4dcd2c9Test
https://doaj.org/article/987313e68b584a3482591ce5d30cb479Test

30

Benchmark dose assessment for coke oven emissions-induced telomere length effects in occupationally exposed workers in China

المؤلفون: Junfeng Zhao, Yuhong Zhang, Leike Li, Pengpeng Wang, Yongli Yang, Yawei Zhang, Feifei Feng, Guoyu Li, Sihua Wang, Xiaolei Feng, Lei Li, Tuanwei Wang, Wu Yao, Zhen Yan, Wei Wang, Xiaoshan Zhou, Xiaoran Duan, Yanbin Wang

المصدر: Ecotoxicology and Environmental Safety. 182:109453

مصطلحات موضوعية: Adult, Male, China, Coke oven, Adolescent, Health, Toxicology and Mutagenesis, 0211 other engineering and technologies, Air Pollutants, Occupational, 02 engineering and technology, 010501 environmental sciences, complex mixtures, 01 natural sciences, Andrology, Young Adult, Occupational Exposure, Humans, Medicine, Coke, 0105 earth and related environmental sciences, 021110 strategic, defence & security studies, Dose-Response Relationship, Drug, business.industry, technology, industry, and agriculture, Public Health, Environmental and Occupational Health, General Medicine, Middle Aged, Telomere, Pollution, Peripheral blood, Benchmarking, Oxidative Stress, Case-Control Studies, Dose assessment, Female, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcee9b69029fa66105335cc739e931cTest
https://doi.org/10.1016/j.ecoenv.2019.109453Test

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