يعرض 71 - 80 نتائج من 706 نتيجة بحث عن '"Kim, Jongsung"', وقت الاستعلام: 0.73s تنقيح النتائج
  1. 71
    دورية أكاديمية
  2. 72

    المساهمون: 安藤 和久, 中村 好甫, 太田 淳平, 大矢 龍弥, 川本 吉太郎, 佐々木 龍平, 藤原 由佳, 金原 遼, 武島 千明, 三戸部 由幸, 澤田 百花, 俵 龍太朗, 藤井 冴佳, 安藤, 和久, 中村, 好甫, 太田, 淳平, 大矢, 龍弥, 川本, 吉太郎, 佐々木, 龍平, 藤原, 由佳, 金原, 遼, 武島, 千明, 三戸部, 由幸, 澤田, 百花, 俵, 龍太朗, 藤井, 冴佳

    وصف الملف: application/pdf

  3. 73

    الوصف: はじめに:社会科教師の論争問題学習に対するスタンス調査研究の概要…1 第1部:教員志望学生が「政治的中立性」を議論する場の提供…5 1.概要…5 2.発表資料…7 3.発表に対するコメント…14 第2部:論争問題学習のスタンスに関する現職教員への質問紙調査…25 1.概要…25 2.発表資料…26 3.付録…43 第3部:「同性婚」問題を論争的に扱った現職教員へのインタビュー調査…59 1.概要…59 2.発表資料…60 3.発表に対するコメント…83 EVRI研究プロジェクト叢書 Bulletin of the EVRI Research Project

    وصف الملف: application/pdf

  4. 74
    دورية أكاديمية

    المصدر: Alzheimer's & Dementia ; volume 18, issue S3 ; ISSN 1552-5260 1552-5279

    الوصف: Background Several mutations near the amyloid‐beta peptide (Aβ) of Amyloid Precursor Protein (APP) were reported to as pathogenic mutations in Alzheimer's disease (AD), especially in early‐onset Alzheimer's disease (EOAD). β‐Secretase would cleave APP and release sAPPβ and CTF99. Then, γ‐secretase would cleave CTF99 sequentially in generating Aβ. Previously, APP‐V604M and APP‐V669L mutations (APP Seoul mutation) were found from patients with EOAD and their mutant cell lines were established by CRISPR/Cas9. Their pathogenicity of APP‐V604M was demonstrated the mutant cells from observing the increased both of Aβ 42/40 ratio and oligomers. For APP‐V669L, the decreased ratio Aβ 42/40 was noticeable from the elevation of Aβ 40 . Still, increased Aβ oligomers were measured. Here, their pathogenicity was supported by measuring β‐secretase activity in above mutant cells. Method Previously, APP‐V604M and APP‐V669L cells were generated by CRISPR/Cas9. Cells were seeded and incubated for 48 h. After washing, conditioned media was added and incubated for 48 h. Afterwards, cytosolic proteins and solubilized membrane were extracted with the commercial kit. β‐secretase activities were measured with the substrate at ex/em 355/510 nm. Result Differences of β‐secretase activity were observed from above mutations in comparison with control. From the cytosolic protein fractions, the increased β‐secretase activity was observed from APP‐V604M, whereas the decreased activity was monitored from APP‐V669L. Interestingly, from the solubilized membrane fractions, the higher β‐secretase activities were seen than cytosolic protein tractions. The similar activities were measured between APP‐V604M and the control, whereas the decreased β‐secretase activities were measured in APP‐V669L than the control. Conclusion Since APP mutations would directly affect by β‐secretase in generating Aβ, it was important to monitor the β‐secretase activity for supporting the mutant. Here, differences in β‐secretase activities were quantified in ...

  5. 75
    دورية أكاديمية

    المؤلفون: Won, Sia, Kim, Jongsung

    المصدر: Korean Journal of Chemical Engineering ; volume 39, issue 10, page 2826-2833 ; ISSN 0256-1115 1975-7220

    مصطلحات موضوعية: General Chemical Engineering, General Chemistry

  6. 76
    دورية أكاديمية

    المساهمون: institute for information and communications technology promotion

    المصدر: Cryptography and Communications ; volume 14, issue 4, page 849-874 ; ISSN 1936-2447 1936-2455

  7. 77
    دورية أكاديمية
  8. 78
    دورية أكاديمية

    المساهمون: National Research Foundation of Korea

    المصدر: Biomaterials Science ; volume 10, issue 7, page 1680-1696 ; ISSN 2047-4830 2047-4849

    الوصف: Dynamic tracking of cancer cells with two-photon excitable polyphenolic carbon dots with superior tumor targeting properties.

  9. 79
    دورية أكاديمية

    المساهمون: National Natural Science Foundation of China, National Research Foundation of Korea

    المصدر: Biomaterials Science ; volume 10, issue 13, page 3527-3539 ; ISSN 2047-4830 2047-4849

    الوصف: Schematic for the synthesis of polyphenolic multifunctional GelMA-CQD hydrogel as a potential candidate for antiaging and in vivo wound-healing applications.

  10. 80
    دورية أكاديمية

    المصدر: Communications in Mathematical Sciences ; volume 20, issue 6, page 1763-1783 ; ISSN 1539-6746 1945-0796

    مصطلحات موضوعية: Applied Mathematics, General Mathematics