المؤلفون: Kim, Ji-Sun, Kim, Byung Guk, Kim, Dong-Hyun, Hwang, Se Hwan

المصدر: Brazilian Journal of Otorhinolaryngology. October 2021 87(5)

مصطلحات موضوعية: Tonsillectomy, Pillar suture, Postoperative hemorrhage, Postoperative pain, Meta-analysis

الوصف: Introduction: Several surgical techniques have been used during tonsillectomy to reduce complications. Objectives: To assess the effects of pillar suture in conjunction with tonsillectomy as compared to tonsillectomy without suture in children. Methods: Two authors independently searched five databases (PubMed, SCOPUS, Embase, the Web of Science, and the Cochrane database) for studies published as recent as December 2018. Of the included studies, we compared tonsillectomy and pillar suture in combination (suture groups) with tonsillectomy alone,without suture, (control group). Postoperative pain intensity and other morbidities (e.g., postoperative bleeding, palatal hematoma, discomfort, and pillar edema) were measured during the postoperative period. Results: Postoperative bleeding [primary (OR = 0.47 [0.27; 0.81]) and secondary (OR = 0.14 [0.02; 0.78]) were significantly decreased in the pillar suture group compared to the control group. There were no significant differences between the two groups in postoperative pain at day 7 (SMD = −0.39 [−0.79; 0.00]), palatal hematoma (OR = 5.00 [0.22; 112.88]), palatal discomfort sensation (OR = 2.62 [0.60; 11.46]), site infection (OR = 5.27 [0.24; 113.35]), and velopharyngeal insufficiency (OR = 2.82 [0.11; 74.51]). By contrast, pillar edema (OR = 9.55 [4.29; 21.29]) was significantly increased in the pillar suture group compared to the control group. Conclusions: Pillar suture combined with tonsillectomy may reduce postoperative bleeding incidence despite increasing pillar edema in pediatric tonsillectomy. Postoperative pain-relief, palatal hematoma, palatal discomfort sensation, site infection, and velopharyngeal insufficiency were not significantly altered compared to tonsillectomy alone. However, further studies are needed to corroborate the results of this study.

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الوصول الحر: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942021000500583Test

المؤلفون: Kim, Han Sol, Kim, Ji-Sun, Suh, Min Kuk, Eom, Mi Kyung, Lee, Jiyoung, Lee, Jung-Sook

المصدر: Scientific Reports ; volume 14, issue 1 ; ISSN 2045-2322

مصطلحات موضوعية: Multidisciplinary

الوصف: The rhizosphere microbial community is closely associated with plant disease by regulating plant growth, agricultural production, nutrient availability, plant hormone and adaptation to environmental changes. Therefore, it is very important to identify the rhizosphere microbes around plant roots and understand their functions. While studying the differences between the rhizosphere microbiota of healthy and diseased apple trees to find the cause of apple tree disease, we isolated a novel strain, designated as B3-10 T , from the rhizosphere soil of a healthy apple tree. The genome relatedness indices between strain B3-10 T and other type species of family Chitinophagaceae were in the ranges of 62.4–67.0% for ANI, 18.6–32.1% for dDDH, and 39.0–56.6% for AAI, which were significantly below the cut‑off values for the species delineation, indicating that strain B3-10 T could be considered to represent a novel genus in family Chitinophagaceae. Interestingly, the complete genome of strain B3-10 T contained a number of genes encoding ACC-deaminase, siderophore production, and acetoin production contributing to plant-beneficial functions. Furthermore, strain B3-10 T was found to significantly promote the growth of shoots and roots of the Nicotiana benthamiana , which is widely used as a good model for plant biology, demonstrating that strain B3-10 T , a rhizosphere microbe of healthy apple trees, has the potential to promote growth and reduce disease. The phenotypic, chemotaxonomic, phylogenetic, genomic, and physiological properties of this plant growth-promoting (rhizo)bacterium, strain B3-10 T supported the proposal of a novel genus in the family Chitinophagaceae , for which the name Rhizosphaericola mali gen. nov., sp. nov. (= KCTC 72123 T = NBRC 114178 T ).

الإتاحة: https://doi.org/10.1038/s41598-024-51492-yTest
https://www.nature.com/articles/s41598-024-51492-y.pdfTest
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المؤلفون: Kim, Ji-Sun, Yoon, Ye Eun, Shin, Jaeeun, Lee, Sang Jun, Lee, Sung-Joon

المصدر: Journal of Functional Foods ; volume 116, page 106174 ; ISSN 1756-4646

مصطلحات موضوعية: Nutrition and Dietetics, Medicine (miscellaneous), Food Science

الإتاحة: https://doi.org/10.1016/j.jff.2024.106174Test
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المؤلفون: Jeong, Bohyeon, Kim, Ji-Sun, Kwon, A Ra, Lee, Jangjae, Park, Subin, Koo, Jahong, Lee, Wang Sik, Baek, Jeong Yeob, Shin, Won-Ho, Lee, Jung-Sook, Jeong, Jinyoung, Kim, Won Kon, Jung, Cho-Rok, Kim, Nam-Soon, Cho, Sung-Hee, Lee, Da Yong

المساهمون: Korea Research Institute of Chemical Technology, Korea Ministry of Education, Korea Research Institute of Bioscience and Biotechnology, Korea Ministry of Science and ICT, National Research Foundation of Korea, Ministry of Science, ICT and Future Planning, Chungnam National University

المصدر: Environment International ; volume 185, page 108522 ; ISSN 0160-4120

مصطلحات موضوعية: General Environmental Science

الإتاحة: https://doi.org/10.1016/j.envint.2024.108522Test
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المؤلفون: Kim, Ji-Sun, Jang, Seung-Hyun

المصدر: Journal of Coastal Research, 2021 Oct 01, 345-349.

الوصول الحر: https://www.jstor.org/stable/48638776Test

المؤلفون: Jeon, Ji‐Young, Kim, Min‐Ji, Im, Yong‐Jin, Kim, Eun‐Young, Kim, Ji Sun, Kwon, Ki Tae, Hwang, Jeong‐Hwan, Kim, Jong Seung, Kim, Min‐Gul

المصدر: Clinical Pharmacology & Therapeutics ; volume 113, issue 6, page 1274-1283 ; ISSN 0009-9236 1532-6535

الوصف: To protect people from severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) infection, tremendous research efforts have been made toward coronavirus disease 19 (COVID‐19) treatment development. Externally controlled trials (ECTs) may help reduce their development time. To evaluate whether ECT using real‐world data (RWD) of patients with COVID‐19 is feasible enough to be used for regulatory decision making, we built an external control arm (ECA) based on RWD as a control arm of a previously conducted randomized controlled trial (RCT), and compared it to the control arm of the RCT. The electronic health record (EHR)‐based COVID‐19 cohort dataset was used as RWD, and three Adaptive COVID‐19 Treatment Trial (ACTT) datasets were used as RCTs. Among the RWD datasets, eligible patients were evaluated as a pool of external control subjects of the ACTT‐1, ACTT‐2, and ACTT‐3 trials, respectively. The ECAs were built using propensity score matching, and the balance of age, sex, and baseline clinical status ordinal scale as covariates between the treatment arms of Asian patients in each ACTT and the pools of external control subjects was assessed before and after 1:1 matching. There was no statistically significant difference in time to recovery between ECAs and the control arms of each ACTT. Among the covariates, the baseline status ordinal score had the greatest influence on the building of ECA. This study demonstrates that ECA based on EHR data of COVID‐19 patients could sufficiently replace the control arm of an RCT, and it is expected to help develop new treatments faster in emergency situations, such as the COVID‐19 pandemic.

الإتاحة: https://doi.org/10.1002/cpt.2882Test

المؤلفون: Doo, Jeon Gang, Lee, Hojung, Jeon, Seung Yeon, Kim, Ji Sun

المصدر: Ear, Nose & Throat Journal ; page 014556132311713 ; ISSN 0145-5613 1942-7522

مصطلحات موضوعية: Otorhinolaryngology

الوصف: Basal cell adenomas (BCA) arising from the nasal cavity or paranasal sinuses are very rare. A 64-year-old male patient was suspected of having a malignant tumor after undergoing preoperative computed tomography scans and magnetic resonance imaging. The intraoperative frozen section showed a malignant tumor; however, the final diagnosis revealed BCA with atypia, tubular pattern.

الإتاحة: https://doi.org/10.1177/01455613231171335Test

المؤلفون: Kim, Kyoung Su, Tiffany, Eunike, Lee, Ji-Young, Oh, Ara, Jin, Hyeon-Su, Kim, Ji-Sun, Lee, Jung-Sook, Nam, Myung Hee, Hong, Soo-Jong, Park, Sowon, Koh, Hong, Kim, Bong-Soo, Lee, Yun Kyung, Lee, Dong-Woo

المساهمون: Bio & Medical Technology Development Program of the National Research Foundation (NRF) of Korea, Ministry of Science and ICT (MSIT), Republic of Korea, Bioindustrial Technology Development Program of Korea, Ministry of Trade, Industry and Energy

المصدر: Gut Microbes ; volume 15, issue 1 ; ISSN 1949-0976 1949-0984

الإتاحة: https://doi.org/10.1080/19490976.2023.2221811Test

المؤلفون: Sihn, Duho, Kim, Ji Sun, Kwon, Oh-Sang, Kim, Sung-Phil

المصدر: Frontiers in Psychiatry ; volume 14 ; ISSN 1664-0640

الوصف: Introduction Identifying biomarkers for depression from brain activity is important for the diagnosis and treatment of depression disorders. We investigated spatial correlations of the amplitude fluctuations of electroencephalography (EEG) oscillations as a potential biomarker of depression. The amplitude fluctuations of EEG oscillations intrinsically reveal both temporal and spatial correlations, indicating rapid and functional organization of the brain networks. Amid these correlations, long-range temporal correlations are reportedly impaired in patients with depression, exhibiting amplitude fluctuations closer to a random process. Based on this occurrence, we hypothesized that the spatial correlations of amplitude fluctuations would also be altered by depression. Methods In the present study, we extracted the amplitude fluctuations of EEG oscillations by filtering them through infraslow frequency band (0.05–0.1 Hz). Results We found that the amplitude fluctuations of theta oscillations during eye-closed rest depicted lower levels of spatial correlation in patients with major depressive disorder (MDD) compared to control individuals. This breakdown of spatial correlations was most prominent in the left fronto - temporal network, specifically in patients with current MDD rather than in those with past MDD. We also found that the amplitude fluctuations of alpha oscillations during eye-open rest exhibited lower levels of spatial correlation in patients with past MDD compared to control individuals or patients with current MDD. Discussion Our results suggest that breakdown of long-range spatial correlations may offer a biomarker for the diagnosis of depression (current MDD), as well as the tracking of the recovery from depression (past MDD).

الإتاحة: https://doi.org/10.3389/fpsyt.2023.1132996Test

المؤلفون: Kim, Ji Sun, Lee, Sang Ah

المساهمون: National Research Foundation of Korea, Seoul National University

المصدر: Cell Reports ; volume 42, issue 8, page 112989 ; ISSN 2211-1247

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology

الإتاحة: https://doi.org/10.1016/j.celrep.2023.112989Test
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