المؤلفون: Hong, Soojung, Lee, Juhee, Kim, Yunhee, Kim, Eunjee, Shin, Kunyoo

المساهمون: National Research Foundation of Korea, Samsung Science and Technology Foundation, Samsung

المصدر: Bioengineering & Translational Medicine ; ISSN 2380-6761 2380-6761

الوصف: Self‐organizing brain organoids provide a promising tool for studying human development and disease. Here we created human forebrain organoids with stable and homogeneous expression of channelrhodopsin‐2 (ChR2) by generating AAVS1 safe harbor locus‐targeted, ChR2 knocked‐in human pluripotent stem cells (hPSCs), followed by the differentiation of these genetically engineered hPSCs into forebrain organoids. The resulting ChR2‐expressing human forebrain organoids showed homogeneous cellular expression of ChR2 throughout entire regions without any structural and functional perturbations and displayed consistent and robust neural activation upon light stimulation, allowing for the non‐virus mediated, spatiotemporal optogenetic control of neural activities. Furthermore, in the hybrid platform in which brain organoids are connected with spinal cord organoids and skeletal muscle spheroids, ChR2 knocked‐in forebrain organoids induced strong and consistent muscle contraction upon brain‐specific optogenetic stimulation. Our study thus provides a novel, non‐virus mediated, preclinical human organoid system for light‐inducible, consistent control of neural activities to study neural circuits and dynamics in normal and disease‐specific human brains as well as neural connections between brain and other peripheral tissues.

الإتاحة: https://doi.org/10.1002/btm2.10690Test

المؤلفون: Lee, Dongjae, Kim, Eunjee, Woo, Hyeonjae, Jeon, Chang-Yeop, Yoon, Junghee, Choi, Jihye

المساهمون: National Research Foundation

المصدر: Frontiers in Bioengineering and Biotechnology ; volume 12 ; ISSN 2296-4185

مصطلحات موضوعية: Biomedical Engineering, Histology, Bioengineering, Biotechnology

الوصف: Magnetic resonance imaging (MRI) is essential for evaluating cerebellar compression in patients with craniocervical junction abnormalities (CJA). However, it is limited in depicting cortical bone because of its short T2 relaxation times, low proton density, and organized structure. Fast field echo resembling a computed tomography (CT) scan using restricted echo-spacing (FRACTURE) MRI, is a new technique that offers CT-like bone contrast without radiation. This study aimed to assess the feasibility of using FRACTURE MRI for craniocervical junction (CCJ) assessment compared with CT and conventional MRI, potentially reducing the need for multiple scans and radiation exposure, and simplifying procedures in veterinary medicine. CT and MRI of the CCJ were obtained from five healthy beagles. MRI was performed using three-dimensional (3D) T1-weighted, T2-weighted, proton density-weighted (PDW), single echo-FRACTURE (sFRACTURE), and multiple echo-FRACTURE (mFRACTURE) sequences. For qualitative assessment, cortical delineation, trabecular bone visibility, joint space visibility, vertebral canal definition, overall quality, and artifacts were evaluated for each sequence. The geometrical accuracy, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were quantified. Both sFRACTURE and CT images provided significantly higher scores for cortical delineation and trabecular bone visibility than conventional MRI. Joint space visibility and vertebral canal definition were similar to those observed on CT images, regardless of the MR sequence. In the quantitative assessment, the distances measured on T2-weighted images differed significantly from those measured on CT. There were no significant differences between the distances taken using T1-weighted, PD-weighted, sFRACTURE, mFRACTURE and those taken using CT. T1-weighted and sFRACTURE had a higher SNR for trabecular bone than CT. The CNR between the cortical bone and muscle was high on CT and FRACTURE images. However, the CNR between the cortical and trabecular bones was ...

الإتاحة: https://doi.org/10.3389/fbioe.2024.1297675Test

المؤلفون: Ryu, Sanghwa, Park, Soomin, Kim, Eunjee, Woo, Hyeonjae, Jeon, Chang-yeop, Yoon, Junghee, Choi, Jihye

المصدر: Frontiers in Veterinary Science ; volume 11 ; ISSN 2297-1769

مصطلحات موضوعية: General Veterinary

الوصف: Shoulder disease is a common cause of forelimb lameness in dogs. Determining the precise underlying cause of shoulder lameness can be challenging, especially in veterinary practice. Computerized tomography (CT) is often the preferred imaging modality for bone evaluation; however, it uses ionizing radiation and provides limited soft tissue contrast. Conversely, magnetic resonance imaging (MRI) offers excellent soft tissue contrast but has limitations in bone imaging. This study aimed to introduce a new technical innovation that enhances cortical and trabecular bone contrast on MRI, which we refer to as Fast Field Echo Resembling a CT Using Restricted Echo-Spacing (FRACTURE). In this prospective pilot study, we aimed to evaluate the use of FRACTURE, CT, and conventional MRI sequences in assessing the normal canine shoulder using a 3.0 Tesla MRI scanner. Five research beagle dogs were included, and the following pulse sequences were acquired for each dog (1): three-dimensional (3D) FRACTURE, (2) T2-weighted (T2W) images using 3D turbo spin echo (TSE), (3) T1-weighted (T1W) images using 3D TSE, (4) PD-weighted (PDW) images using 3D TSE, and (5) CT. Various parameters, including the delineation of cortical bone (intertubercular groove, greater tubercle, and lesser tubercle), conspicuity of the trabecular bone, shoulder joint visualization, and image quality, were measured for each dog and sequence. In all sequences, the shoulder joint was successfully visualized in all planes with mild motion artifacts. The intertubercular groove was best visualized on CT and FRACTURE. Both the greater and lesser tubercles were easily identified on the CT, FRACTURE, and PDW images. The trabecular pattern scored significantly higher in the CT and FRACTURE images compared to the T1W, T2W, and PDW images. Overall, the visualization of the shoulder joint was excellent in all sequences except for T1W. The use of FRACTURE in combination with conventional MRI sequences holds promise for facilitating not only soft tissue evaluation but also ...

الإتاحة: https://doi.org/10.3389/fvets.2024.1298133Test

المؤلفون: Kim, Eunjee, Park, Sunyoung

المصدر: Kybernetes, 2020, Vol. 50, Issue 5, pp. 1521-1538.

الوصول الحر: http://www.emeraldinsight.com/doi/10.1108/K-03-2020-0169Test

المؤلفون: Kim, Eunjee, Song, Donghyun, Park, Dasom, Kim, Hyorim, Shin, Gwanseob

المساهمون: National Research Foundation of Korea, Ministry of Science, ICT and Future Planning

المصدر: Journal of Biomechanics ; volume 166, page 112053 ; ISSN 0021-9290

مصطلحات موضوعية: Rehabilitation, Biomedical Engineering, Orthopedics and Sports Medicine, Biophysics

الإتاحة: https://doi.org/10.1016/j.jbiomech.2024.112053Test
https://api.elsevier.com/content/article/PII:S0021929024001301?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0021929024001301?httpAccept=text/plainTest

المؤلفون: Song, Donghyun, Park, Dasom, Kim, Eunjee, Shin, Gwanseob

المساهمون: National Research Foundation of Korea, Ministry of Science, ICT and Future Planning

المصدر: International Journal of Industrial Ergonomics ; volume 100, page 103554 ; ISSN 0169-8141

مصطلحات موضوعية: Public Health, Environmental and Occupational Health, Human Factors and Ergonomics

الإتاحة: https://doi.org/10.1016/j.ergon.2024.103554Test
https://api.elsevier.com/content/article/PII:S0169814124000106?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0169814124000106?httpAccept=text/plainTest

المؤلفون: Potortì, Francesco, Park, Sangjoon, Crivello, Antonino, Palumbo, Filippo, GIROLAMI, MICHELE, Barsocchi, Paolo, Lee, Soyeon, Torres-Sospedra, Joaquín, Jimenez Ruiz, Antonio Ramon, Perez-Navarro, Antoni, Mendoza-Silva, Germán Martín, Seco, Fernando, ortiz, miguel, PERUL, Johan, Renaudin, Valerie, Kang, Hyunwoong, Park, Soyoung, Lee, Jae Hong, Park, Chan Gook, Ha, Jisu, Han, JaeSeung, Park, Changjun, Kim, Keunhye, Lee, Yonghyun, Gye, Seunghun, lee, keumryeol, Kim, Eunjee, Choi, Jeongsik, choi, Yang-Seok, Talwar, Shilpa, Cho, Seong Yun, Ben-Moshe, Boaz, Scherbakov, Alex, Antsfeld, Leonid, Sansano-Sansano, Emilio, Chidlovskii, Boris, Kronenwett, Nikolai, Prophet, Silvia, Landay, Yael, Marbel, Revital, Zheng, Lingxiang, Peng, Ao, Lin, Zhichao, Wu, Bang, Ma, Chengqi, Poslad, Stefan, Selviah, David, Wu, Wei, Ma, Zixiang, Zhang, Wenchao, Wei, Dongyan, Yuan, Hong, Jiang, Jun-Bang, Huang, Shao-Yung, Liu, Jing-Wen, Su, Kuan-Wu, Leu, Jenq-Shiou, Nishiguchi, Kazuki, BOUSSELHAM, Walid, Uchiyama, Hideaki, Thomas, Diego, Shimada, Atsushi, Taniguchi, Rin-ichiro, Cortés Puschel, Vicente, Lungenstrass, Tomás, Ashraf, Imran, Lee, Chanseok, Ali, Muhammad Usman, Im, Yeongjun, Kim, Gunzung, Eom, Jeongsook, Hur, Soojung, Park, Yongwan, Opiela, Miroslav, Moreira, Adriano, Nicolau, Maria João, Pendão, Cristiano, Silva, Ivo, Meneses, Filipe, Costa, António, Trogh, Jens, Plets, David, Chien, Ying-Ren, Chang, Tzu-Yu, Fang, Shih-Hau, Tsao, Yu

مصطلحات موضوعية: indoor localisation, indoor navigation, competition, benchmarking, smartphone-based positioning, foot-mounted pedestrian dead reckoning, Wi-Fi fingerprinting, magnetic field, camera-based positioning, inertial-based positioning, sensor fusion, Kalman filter, particle filter, stakeholders, atmospheric measurements, particle measurements, real-time systems, wireless fidelity, sensor systems

الوصف: IPIN 2019 Competition, sixth in a series of IPIN competitions, was held at the CNR Research Area of Pisa (IT), integrated into the program of the IPIN 2019 Conference. It included two on-site real-time Tracks and three off-site Tracks. The four Tracks presented in this paper were set in the same environment, made of two buildings close together for a total usable area of 1000 m 2 outdoors and and 6000 m 2 indoors over three floors, with a total path length exceeding 500 m. IPIN competitions, based on the EvAAL framework, have aimed at comparing the accuracy performance of personal positioning systems in fair and realistic conditions: past editions of the competition were carried in big conference settings, university campuses and a shopping mall. Positioning accuracy is computed while the person carrying the system under test walks at normal walking speed, uses lifts and goes up and down stairs or briefly stops at given points. Results presented here are a showcase of state-of-the-art systems tested side by side in real-world settings as part of the on-site real-time competition Tracks. Results for off-site Tracks allow a detailed and reproducible comparison of the most recent positioning and tracking algorithms in the same environment as the on-site Tracks.

وصف الملف: application/pdf

العلاقة: Development of human enhancement fire helmet and fire suppression support system; Basic Science Research Program; ICT Research and Development Program of MSIP/IITP (Development of Precise Positioning Technology for the Enhancement of Pedestrian Position/Spatial Cognition and Sports Competition Analysis); MICROCEBUS; REPNIN PLUS; TECHNOFUSION(III)CM; Development of wireless communication tracking-based location information system in disaster scene for fire-fighters and person who requested rescue; Strategic Priority Research Program; IEEE Access, Vol. 8 (2020); F. Potortì et al., "The IPIN 2019 Indoor Localisation Competition—Description and Results," in IEEE Access, vol. 8, pp. 206674-206718, 2020, doi:10.1109/ACCESS.2020.3037221.; http://hdl.handle.net/10234/200929Test

الإتاحة: https://doi.org/10.1109/ACCESS.2020.3037221Test
http://hdl.handle.net/10234/200929Test

المؤلفون: Kim, EunJee

المصدر: Online Submission. 2007.

تمت مراجعته من قبل الزملاء: N

Page Count: 8

الواصفات: Content Analysis, Organizational Climate, Cultural Influences, Knowledge Management, Information Technology, Labor Force Development

مستخلص: This paper presents an integrative review of literature on cultural dimensions that have been suggested as facilitative and inhibitive to knowledge sharing in organizations. Content analysis was conducted on articles related to national, organizational and professional culture and knowledge sharing process. Based on a review of existing literature in this area, this paper presents a conceptual framework that identifies cultural factors that significantly influence knowledge sharing process. (Contains 1 figure.)

Abstractor: As Provided

المؤلفون: Freeman, Mara, Kim, EunJee, Kim, Eunok Alice

المصدر: Online Submission. 2006.

تمت مراجعته من قبل الزملاء: N

Page Count: 7

الواصفات: Content Analysis, Labor Force Development, Human Resources, Improvement, Job Training, Performance Factors, Journal Articles, Educational Methods

مستخلص: Increasing interest in research on workplace learning and performance provides an ideal opportunity to examine how much research is actually published and to identify the focus of research in HRD. This study involved a content analysis of articles on workplace learning and performance published in the four AHRD journals. Results indicated studies addressing workplace learning and performance accounted for about one-third of all articles published in the AHRD journals. (Contains 5 tables.)

Abstractor: Author

المؤلفون: Potorti, Francesco, Park, Sangjoon, Crivello, Antonino, Palumbo, Filippo, Girolami, Michele, Barsocchi, Paolo, Lee, Soyeon, Torres-Sospedra, Joaquin, Ruiz, Antonio Ramon Jimenez, Perez-Navarro, Antoni, Mendoza-Silva, German Martin, Seco, Fernando, Ortiz, Miguel, Perul, Johan, Renaudin, Valerie, Kang, Hyunwoong, Park, Soyoung, Lee, Jae Hong, Park, Chan Gook, Ha, Jisu, Han, Jaeseung, Park, Changjun, Kim, Keunhye, Lee, Yonghyun, Gye, Seunghun, Lee, Keumryeol, Kim, Eunjee, Choi, Jeong-Sik, Choi, Yang-Seok, Talwar, Shilpa, Cho, Seong Yun, Ben-Moshe, Boaz, Scherbakov, Alex, Antsfeld, Leonid, Sansano-Sansano, Emilio, Chidlovskii, Boris, Kronenwett, Nikolai, Prophet, Silvia, Landay, Yael, Marbel, Revital, Zheng, Lingxiang, Peng, Ao, Lin, Zhichao, Wu, Bang, Ma, Chengqi, Poslad, Stefan, Selviah, David R., Wu, Wei, Ma, Zixiang, Zhang, Wenchao, Wei, Dongyan, Yuan, Hong, Jiang, Jun-Bang, Huang, Shao-Yung, Liu, Jing-Wen, Su, Kuan-Wu, Leu, Jenq-Shiou, Nishiguchi, Kazuki, Bousselham, Walid, Uchiyama, Hideaki, Thomas, Diego, Shimada, Atsushi, Taniguchi, Rin-Ichiro, Puschel, Vicente Cortes, Poulsen, Tomas Lungenstrass, Ashraf, Imran, Lee, Chanseok, Ali, Muhammad Usman, Im, Yeongjun, Kim, Gunzung, Eom, Jeongsook, Hur, Soojung, Park, Yongwan, Opiela, Miroslav, Moreira, Adriano, Nicolau, Maria Joao, Pendao, Cristiano, Silva, Ivo, Meneses, Filipe, Costa, Antonio, Trogh, Jens, Plets, David, Chien, Ying-Ren, Chang, Tzu-Yu, Fang, Shih-Hau, Tsao, Yu

المصدر: IEEE access, 8, 206674–206718 ; ISSN: 2169-3536

مصطلحات موضوعية: ddc:620, Engineering & allied operations, info:eu-repo/classification/ddc/620

الوصف: PIN 2019 Competition, sixth in a series of IPIN competitions, was held at the CNR Research Area of Pisa (IT), integrated into the program of the IPIN 2019 Conference. It included two on-site real-time Tracks and three off-site Tracks. The four Tracks presented in this paper were set in the same environment, made of two buildings close together for a total usable area of 1000 m 2 outdoors and and 6000 m 2 indoors over three floors, with a total path length exceeding 500 m. IPIN competitions, based on the EvAAL framework, have aimed at comparing the accuracy performance of personal positioning systems in fair and realistic conditions: past editions of the competition were carried in big conference settings, university campuses and a shopping mall. Positioning accuracy is computed while the person carrying the system under test walks at normal walking speed, uses lifts and goes up and down stairs or briefly stops at given points. Results presented here are a showcase of state-of-the-art systems tested side by side in real-world settings as part of the on-site real-time competition Tracks. Results for off-site Tracks allow a detailed and reproducible comparison of the most recent positioning and tracking algorithms in the same environment as the on-site Tracks.

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/wos/000594446900001; info:eu-repo/semantics/altIdentifier/issn/2169-3536; https://publikationen.bibliothek.kit.edu/1000130123Test; https://publikationen.bibliothek.kit.edu/1000130123/104023450Test; https://doi.org/10.5445/IR/1000130123Test

الإتاحة: https://doi.org/10.5445/IR/1000130123Test
https://doi.org/10.1109/ACCESS.2020.3037221Test
https://publikationen.bibliothek.kit.edu/1000130123Test
https://publikationen.bibliothek.kit.edu/1000130123/104023450Test