المؤلفون: Mohapatra, Debananda, Kang, Hyun Jin, Lee, Sanghyuk, Son, Yeseul, Ansari, Mohd Zahid, Kang, Youngho, Lee, Jung Woo, Kim, Soo‐Hyun

المساهمون: National Research Foundation of Korea, Korea Semiconductor Research Consortium, Ministry of Trade, Industry and Energy

المصدر: Small ; ISSN 1613-6810 1613-6829

الوصف: Global healthcare based on the Internet of Things system is rapidly transforming to measure precise physiological body parameters without visiting hospitals at remote patients and associated symptoms monitoring. 2D materials and the prevailing mood of current ever‐expanding MXene‐based sensing devices motivate to introduce first the novel iridium (Ir) precious metal incorporated vanadium (V)‐MXene via industrially favored emerging atomic layer deposition (ALD) techniques. The current work contributes a precise control and delicate balance of Ir single atomic forms or clusters on the V‐MXene to constitute a unique precious metal‐MXene embedded heterostructure (Ir‐ALD@V‐MXene) in practical real‐time sensing healthcare applications to thermography with human–machine interface for the first time. Ir‐ALD@V‐MXene delivers an ultrahigh durability and sensing performance of 2.4% °C −1 than pristine V‐MXene (0.42% °C −1 ), outperforming several conventionally used MXenes, graphene, underscoring the importance of the Ir‐ALD innovative process. Aberration‐corrected advanced ultra‐high‐resolution transmission/scanning transmission electron microscopy confirms the presence of Ir atomic clusters on well‐aligned 2D‐layered V‐MXene structure and their advanced heterostructure formation (Ir‐ALD@V‐MXene), enhanced sensing mechanism is investigated using density functional theory (DFT) computations. A rational design empowering the Ir‐ALD process on least explored V‐MXene can potentially unfold further precious metals ALD‐process developments for next‐generation wearable personal healthcare devices.

الإتاحة: https://doi.org/10.1002/smll.202402003Test

المؤلفون: Kang, Hyun Jin, Torres, Karen, Kim, Michelle S.

المصدر: Epilepsy & Behavior Reports ; page 100663 ; ISSN 2589-9864

مصطلحات موضوعية: Behavioral Neuroscience, Neurology (clinical), Neurology

الإتاحة: https://doi.org/10.1016/j.ebr.2024.100663Test
https://api.elsevier.com/content/article/PII:S2589986424000200?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2589986424000200?httpAccept=text/plainTest

المؤلفون: Kang, Hyun-Jin, Lee, Sang-Hoon, Kim, Han-Shin, Jung, Yong Woo, Park, Hee-Deung

المساهمون: Vaz-Moreira, Ivone, Korea Ministry of Environment, National Research Foundation of Korea

المصدر: PLOS ONE ; volume 18, issue 8, page e0290579 ; ISSN 1932-6203

الوصف: Although detection of gram-negative bacteria (GNB) in body fluids is important for clinical purpose, traditional gram staining and other recently developed methods have inherent limitations in terms of accuracy, sensitivity, and convenience. To overcome the weakness, this study proposed a method detecting GNB based on specific binding of polymyxin B (PMB) to lipopolysaccharides (LPS) of GNB. Fluorescent microscopy demonstrated that surface immobilized PMB using a silane coupling agent was possible to detect fluorescent signal produced by a single Escherichia coli (a model GNB) cell. Furthermore, the signal was selective enough to differentiate between GNB and gram-positive bacteria. The proposed method could detect three cells per ml within one hour, indicating the method was very sensitive and the sensing was rapid. These results suggest that highly multifold PMB binding on each GNB cell occurred, as millions of LPS are present on cell wall of a GNB cell. Importantly, the principle used in this study was realized in a microfluidic chip for a sample containing E . coli cells suspended in porcine plasma, demonstrating its potential application to practical uses. In conclusion, the proposed method was accurate, sensitive, and convenient for detecting GNB, and could be applied clinically.

الإتاحة: https://doi.org/10.1371/journal.pone.0290579Test

المؤلفون: Parsey, Carolyn M., Kang, Hyun Jin, Eaton, Jessica C., McGrath, Margaret E., Barber, Jason, Temkin, Nancy R., Mac Donald, Christine L.

المساهمون: National Institute of Neurological Disorders and Stroke

المصدر: Brain Injury ; volume 37, issue 10, page 1127-1134 ; ISSN 0269-9052 1362-301X

الإتاحة: https://doi.org/10.1080/02699052.2023.2209740Test

المؤلفون: Kim, Michelle S., Torres, Karen, Kang, Hyun Jin, Drane, Daniel L.

المصدر: Clinical Neuropsychologist; Oct2023, Vol. 37 Issue 7, p1530-1547, 18p

مصطلحات موضوعية: TEST validity, PEOPLE with epilepsy, NEUROPSYCHOLOGICAL tests, RECOGNITION (Psychology), MEMORY testing

مستخلص: Objective: While assessment of performance validity is essential to neuropsychological evaluations, use of performance validity tests (PVTs) in an epilepsy population has raised concerns due to factors that may result in performance fluctuations. The current study assessed whether specificity was maintained at previously suggested cutoffs in a confirmed epilepsy population on the Warrington Recognition Memory Test (WRMT) – Words and Test of Memory Malingering (TOMM). Method: Eighty-two confirmed epilepsy patients were administered the WRMT-Words and TOMM as part of a standardized neuropsychological evaluation. Frequency tables were utilized to investigate specificity rates on these two PVTs. Results: The suggested WRMT-Words Accuracy Score cutoff of ≤42 was associated with a specificity rate of 90.2%. Five out of the 8 individuals falling below the Accuracy Score cutoff scored 42, suggesting specificity could be further improved by slightly lowering the cutoff. The WRMT-Words Total Time cutoff of ≥207 seconds was associated with 95.1% specificity. A TOMM Trial 1 cutoff of <40 was associated with 93.9% specificity, while the established cutoff of <45 on Trial 2 and the Retention Trial yielded specificity rates of 98.6% and 100.0%, respectively. Conclusions: Our findings demonstrate acceptable performance on two PVTs in a select confirmed epilepsy population without a history of brain surgery, active seizures during testing, and/or low IQ, irrespective of various factors such as seizure type, seizure lateralization/localization, and language lateralization. The possible presence of interictal discharges were not controlled for in the current study, which may have contributed to reduced PVT performances. [ABSTRACT FROM AUTHOR]

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المؤلفون: Lee, Eun Byul, Oh, Se min, Chong, Yu Ri, Seo, Myung Gyun, Kang, Hyun Jin, Lee, Jeong Rim, Moon, In Sung

المصدر: Transplantation ; volume 107, issue 10S1, page 92-92 ; ISSN 0041-1337

الإتاحة: https://doi.org/10.1097/01.tp.0000993556.15571.26Test

المؤلفون: Kwon, Hyuck, Kang, Hyun-Jin, Park, Yuchan, Bae, Jaeho

المصدر: Water Research ; volume 229, page 119511 ; ISSN 0043-1354

مصطلحات موضوعية: Pollution, Waste Management and Disposal, Water Science and Technology, Ecological Modeling, Environmental Engineering, Civil and Structural Engineering

الإتاحة: https://doi.org/10.1016/j.watres.2022.119511Test
https://api.elsevier.com/content/article/PII:S0043135422014567?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0043135422014567?httpAccept=text/plainTest

المؤلفون: Parsey, Carolyn M, Kang, Hyun Jin, Barber, Jason, Temkin, Nancy, Mac Donald, Christine L

المصدر: Journal of the International Neuropsychological Society ; volume 29, issue s1, page 150-151 ; ISSN 1355-6177 1469-7661

مصطلحات موضوعية: Psychiatry and Mental health, Neurology (clinical), Clinical Psychology, General Neuroscience

الوصف: Objective: Investigate the relationship of chronic neurobehavioral and cognitive symptoms in military personnel with history of blast-related mild TBI and compare to a well-matched group of combat-deployed controls. Participants and Methods: 274 participants (mean age=34 years; mean education=14.75 years; 91.2% male) enrolled in the EVOLVE longitudinal study of combat-deployed military personnel were subdivided into those with history of blast TBI (n=165) and controls without history of blast exposure and TBI (n=109). As part of a larger study, we conducted a sub-analysis of 5-year follow up data. We focused on group differences (Mann-Whitney U) and correlational relationships between self-report neurobehavioral symptoms via the Frontal Systems Behavior Scale (FrSBE) and cognitive performances on measures of attention, working memory, processing speed, and executive functioning including D-KEFS Color Word Interference (CWI), Trailmaking A and B, and the Conners Continuous Performance Test (CPT). Results: The Blast TBI group reported higher levels of neurobehavioral symptoms on the FrSBE (p<.001), including domains of apathy (p<.001), disinhibition (p<.001), and executive dysfunction (p<.001), compared to Controls. On cognitive measures, group differences were observed on CWI Inhibition/Switching (p =.008), Trails B time (p =.010), and CPT commission errors (p =.014), such that the Blast TBI group performed worse than Controls. No significant group differences were observed for CPT omission errors or CPT hit rate (p ’s>.05). After adjustment for multiple comparisons, greater FrSBE apathy correlated with slower performance on Trails A for Blast TBI (r=0.22, p=.014) but not Controls. Apathy endorsement was not significantly related to CPT omission errors for either group (p ’s>.05). Higher endorsement of disinhibition symptoms was associated with worse performance on CWI Inhibition (Blast TBI: r=-0.19, p=.036; Controls: r=-0.28, p=.012) and Inhibition/Switching (Blast TBI: r=-0.23, p=.010; ...

الإتاحة: https://doi.org/10.1017/s1355617723002473Test
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S1355617723002473Test

المؤلفون: Shin, Yujin, Kim, Young Won, Kang, Hyun Jin, Lee, Ju Ha, Byun, Jeong Eun, Yang, Jin-Young, Lee, Jung Woo

المساهمون: Korea Institute of Materials Science, National Research Foundation of Korea, Ministry of Trade, Industry and Energy, Chung Mong-Koo Foundation, Pusan National University

المصدر: Nano Letters ; volume 23, issue 11, page 5391-5398 ; ISSN 1530-6984 1530-6992

الإتاحة: https://doi.org/10.1021/acs.nanolett.2c04752Test

المؤلفون: Song, Jin H., Kang, Hyun-Jin, Luevano, Libia A., Gokhale, Vijay, Wu, Kui, Pandey, Ritu, Sherry Chow, H.-H., Hurley, Laurence H., Kraft, Andrew S.

المساهمون: National Cancer Institute, U.S. Department of Defense

المصدر: Cell Chemical Biology ; volume 26, issue 8, page 1110-1121.e4 ; ISSN 2451-9456

مصطلحات موضوعية: Clinical Biochemistry, Drug Discovery, Pharmacology, Molecular Biology, Molecular Medicine, Biochemistry

الإتاحة: https://doi.org/10.1016/j.chembiol.2019.04.009Test
https://api.elsevier.com/content/article/PII:S2451945619301400?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2451945619301400?httpAccept=text/plainTest