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1دورية أكاديمية
المؤلفون: Jovana Todorovic, Zeljka Stamenkovic, Aleksandar Stevanovic, Natasa Terzic, Katarzyna Kissimova-Skarbek, Fimka Tozija, Enkeleint A. Mechili, Brecht Devleesschauwer, Zorica Terzic-Supic, Milena Vasic, Vesna Bjegovic-Mikanovic, Milena Santric-Milicevic, the COST Action 18218 participants Burden of Disease Collaborator Network
المصدر: Archives of Public Health, Vol 81, Iss 1, Pp 1-15 (2023)
مصطلحات موضوعية: Public aspects of medicine, RA1-1270
الوصف: Abstract Background Despite effective prevention and control strategies, in countries of the Balkan region, cancers are the second leading cause of mortality, closely following circulatory system diseases. Objective To describe trends in the burden of breast, cervical, and colon and rectum cancer in the Balkan region and per country between 1990 and 2019, including a forecast to 2030. Methods We described the 2019 Global Burden of Disease (GBD) estimates for breast, cervical, and colon and rectum cancers in eleven Balkan countries over the period 1990–2019, including incidence, years lived with disability (YLD), years of life lost (YLL), and disability-adjusted life years (DALYs) rates per 100,000 population and accompanied 95% uncertainty interval. With the Autoregressive Integrated Moving Average, we forecasted these rates per country up to 2030. Results In the Balkan region, the highest incidence and DALYs rates in the study period were for colon and rectum, and breast cancers. Over the study period, the DALYs rates for breast cancer per 100,000 population were the highest in Serbia (reaching 670.84 in 2019) but the lowest in Albania (reaching 271.24 in 2019). In 2019, the highest incidence of breast cancer (85 /100,000) and highest YLD rate (64 /100,000) were observed in Greece. Romania had the highest incidence rates, YLD rates, DALY rates, and YLL rates of cervical cancer, with respective 20.59%, 23.39% 4.00%, and 3.47% increases for the 1990/2019 period, and the highest forecasted burden for cervical cancer in 2030. The highest incidence rates, YLD rates and DALY rates of colon and rectum cancers were continuously recorded in Croatia (an increase of 130.75%, 48.23%, and 63.28%, respectively), while the highest YLL rates were in Bulgaria (an increase of 63.85%). The YLL rates due to colon and rectum cancers are forecasted to progress by 2030 in all Balkan countries. Conclusion As most of the DALYs burden for breast, cervical, and colon and rectum cancer is due to premature mortality, the numerous country-specific barriers to cancer early detection and quality and care continuum should be a public priority of multi-stakeholder collaboration in the Balkan region.
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2049-3258Test
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2دورية أكاديمية
المؤلفون: Milos Milincic, Jovana Todorovic, Stefan Dugalic, Ivana Novakovic, Maja Macura, Katarina Lalic, Miroslava Gojnic Dugalic
المصدر: Reports, Vol 7, Iss 2, p 39 (2024)
مصطلحات موضوعية: pregnancy, familial hypercholesterolemia, LDL apheresis, pregnancy outcomes, Medicine (General), R5-920, Medical physics. Medical radiology. Nuclear medicine, R895-920
الوصف: Familial hypercholesterolemia, a genetic disorder marked by elevated low-density lipoprotein cholesterol (LDL-C), poses significant risks for premature atherosclerosis and cardiovascular diseases, particularly during pregnancy. One of the safe methods of treating this condition in pregnancy is with the use of LDL apheresis. We present a 38-year-old primigravida with homozygous Familial Hypercholesterolemia (HoFH), ischemic cardiomyopathy, and angina pectoris. Two years before conception, extremely elevated lipid levels prompted statin therapy and lifestyle changes. Stent placements followed acute myocardial infarction. When planning pregnancy, statins were discontinued, but lipid levels elevated. LDL apheresis was initiated, achieving a 60% reduction. Throughout pregnancy, 16 LDL apheresis sessions were performed every 14 days, maintaining optimal lipid profiles. A cesarean section was performed in the 38th week of gestation, delivering a healthy infant. The patient resumed statin therapy after 8 months of breastfeeding. The patient maintained cardiovascular health, demonstrating the feasibility of controlled HoFH pregnancies. This case highlights the successful management of HoFH during pregnancy using LDL apheresis, ensuring maternal and fetal well-being. Future research on novel treatments and their safety during pregnancy is essential for refining therapeutic approaches in similar cases.
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Sonja Perkovic-Kepeci, Andja Cirkovic, Natasa Milic, Stefan Dugalic, Dejana Stanisavljevic, Milos Milincic, Konstantin Kostic, Nikola Milic, Jovana Todorovic, Ksenija Markovic, Natasa Aleksic Grozdic, Miroslava Gojnic Dugalic
المصدر: Medicina, Vol 59, Iss 8, p 1502 (2023)
مصطلحات موضوعية: diabetes mellitus, pregnancy, Doppler ultrasound, indices, Medicine (General), R5-920
الوصف: Background and Objectives: The aim of this study was to assess the differences in Doppler indices of the uterine (Ut), umbilical (UA), and middle cerebral artery (MCA) in diabetic versus non-diabetic pregnancies by conducting a comprehensive systematic review of the literature with a meta-analysis. Materials and Methods: PubMed, Web of Science, and SCOPUS were searched for studies that measured the pulsatility index (PI), resistance index (RI), and systolic/diastolic ratio index (S/D ratio) of the umbilical artery, middle cerebral artery, and uterine artery in diabetic versus non-diabetic pregnancies. Two reviewers independently evaluated the eligibility of studies, abstracted data, and performed quality assessments according to standardized protocols. The standardized mean difference (SMD) was used as a measure of effect size. Heterogeneity was assessed using the I2 statistic. Publication bias was evaluated by means of funnel plots. Results: A total of 62 publications were included in the qualitative and 43 in quantitative analysis. The UA-RI, UtA-PI, and UtA-S/D ratios were increased in diabetic compared with non-diabetic pregnancies. Subgroup analysis showed that levels of UtA-PI were significantly higher during the third, but not during the first trimester of pregnancy in diabetic versus non-diabetic pregnancies. No differences were found for the UA-PI, UA-S/D ratio, MCA-PI, MCA-RI, MCA-S/D ratio, or UtA-RI between diabetic and non-diabetic pregnancies. Conclusions: This meta-analysis revealed the presence of hemodynamic changes in uterine and umbilical arteries, but not in the middle cerebral artery in pregnancies complicated by diabetes.
وصف الملف: electronic resource
العلاقة: https://www.mdpi.com/1648-9144/59/8/1502Test; https://doaj.org/toc/1010-660XTest; https://doaj.org/toc/1648-9144Test
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4دورية أكاديمية
المؤلفون: Jovana Todorovic, Zorica Terzic-Supic, Jelena Divjak, Zeljka Stamenkovic, Stefan Mandic-Rajcevic, Sanja Kocic, Snezana Ukropina, Roberta Markovic, Olivera Radulovic, Aleksandra Arnaut, Pavle Piperac, Momcilo Mirkovic, Dejan Nesic
المصدر: International Journal of Occupational Medicine and Environmental Health, Vol 34, Iss 6, Pp 737-745 (2021)
مصطلحات موضوعية: students, validation, cbi, study burnout inventory, copenhagen burnout inventory, sbi, Medicine
الوصف: Objectives The aim of this study was to assess the validity and reliability of the Serbian versions of the Copenhagen Burnout Inventory (CBI) and the Study Burnout Inventory (SBI) among fifth-year medical students at 5 universities in Serbia. Material and Methods The study included 573 fifthyear medical students at 5 universities in Serbia. The research instrument consisted of SBI and CBI. The reliability of these instruments was assessed using an internal consistency measure (Cronbach’s α), an intra-class coefficient (ICC) and factor analysis. Results Cronbach’s α for SBI was 0.83, including for exhaustion 0.73, for cynicism 0.70, and for inadequacy 0.48. The test-retest reliability (ICC) was 0.75. Cronbach’s α for personal burnout on CBI was 0.89, for the faculty-related burnout 0.86, and for the faculty-members-related burnout 0.92. Cronbach’s α for CBI was 0.93. The factor analysis for SBI showed 2 factors and for CBI 3 factors. Conclusions This study revealed that the Serbian versions of both SBI and CBI could be used for the assessment of burnout in this population. Int J Occup Med Environ Health. 2021;34(6):737–45
وصف الملف: electronic resource
العلاقة: http://ijomeh.eu/Validation-of-the-Study-Burnout-Inventory-and-the-Copenhagen-Burnout-Inventory-for,133967,0,2.htmlTest; https://doaj.org/toc/1232-1087Test; https://doaj.org/toc/1896-494XTest
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5دورية أكاديمية
المؤلفون: Bojan Stopic, Branislava Medic-Brkic, Katarina Savic-Vujovic, Zeljko Davidovic, Jovana Todorovic, Nada Dimkovic
المصدر: Dose-Response, Vol 20 (2022)
مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950
الوصف: Chronic kidney disease (CKD) is an important factor that contributes to the increase of all-cause morbidity and mortality in the group of non-communicable diseases, and it is also recognized as a strong and independent risk factor that contributes to cardiovascular disease (CVD). CVDs are a consequence of the action of a large number of risk factors among which are traditional and non-traditional. These risk factors have been the subject of a large number of studies which partially explained the unfavorable cardiovascular (CV) outcome of CKD patients. Therefore, valid studies about clinical and biohumoral predictors are of particular importance, especially in the early stages of renal disease, that is, in patients with creatinine clearance below 60 ml/min/1.73 m 2 when preventive measures are most effective. Among potential predictors of adverse CV outcome are biomarkers of inflammation (Interleukin-18—IL-18), oxidative stress (ischemia-modified albumin—IMA; superoxide dismutase—SOD), acute kidney injury (kidney injury molecule - 1—KIM-1; neutrophil gelatinase–associated lipocalin—NGAL), and microribonucleic acids (specific microRNA-133a). In this review, we tried to confirm the relationship between risk factors of CKD and CVD and newer, less frequently examined biomarkers with the occurrence of incidental CV events in renal patients.
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/1559-3258Test
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6دورية أكاديمية
المصدر: South Eastern European Journal of Public Health (2022)
مصطلحات موضوعية: Reproductive health, sexual health, students, medical, knowledge, behavior, Public aspects of medicine, RA1-1270
الوصف: Introduction: Sexually transmitted infections (STIs) along with unintended pregnancies, gender-based violence, and gender inequality represent a serious risk to reproductive health in adolescent age. Comprehensive Sexual Education (CSE) plays a central role among public health interventions designed to prepare young people for these challenges. The aim of our research was to examine knowledge, experience, and behaviors regarding reproductive and sexual health among the population of medical students, as well as the possible connection between reproductive health, information, and study success. Material and methods: A total of 186 second-year and 214 fifth-year medical students were included in the study as a convenient sample taken by random selection. We used a questionnaire of the World Health Organization designed for adolescent sexual and reproductive health. Data were analyzed with the IMB SPSS 25 software. Results: For the second-year students, primary source of information about sex are conversations with their family and friends (37.6%), while for the fifth-year students it is the faculty curriculum (34.7%). Students with personal experience of STIs showed higher average level of knowledge about STIs and reproductive health (p=0.011). Significant positive correlation between the average grade and the level of knowledge about reproductive health was found (r=0.150; p=0.03). Conclusion: This study has shown the diverse sexual life of young medical students in Serbia, combined with risky habits and attitudes, also similarly represented in the world. Further research is needed in order to formulate public health policies adjusted to the needs of the Serbian youth.
وصف الملف: electronic resource
العلاقة: https://www.seejph.com/index.php/seejph/article/view/5481Test; https://doaj.org/toc/2197-5248Test
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7دورية أكاديمية
المؤلفون: Nemanja Rankovic, Jovana Todorovic, Radoje Simic
المصدر: PLoS ONE, Vol 16, Iss 5, p e0251563 (2021)
الوصف: Lateral neck masses (LNM) often present a diagnostic challenge in the practice of pediatric plastic surgeon. The aim of this study is to investigate the clinical and ultrasound (US) characteristics of pediatric LNM in order to make mutual comparison between their entities and enable the most accurate preoperative diagnosis. A cross-sectional study was conducted among 250 pediatric patients treated by surgical excision or sclerotherapy in our institution in the period from July 2009 to June 2019. Lymphatic malformation was the most frequent congenital LNM (60.9%), while reactive or granulomatous lymphadenitis was the most frequent acquired LNM (47%). Congenital anomalies were significantly more often localized in the upper half of the sternocleidomastoid (SCM) muscle region, and had more often soft consistency than acquired ones. Congenital LNM had a 32.37 (3.44-304.63) times higher likelihood of incorrect (p = 0.002) and 5.86 (1.35-25.48) times higher likelihood of undetermined (p = 0.018) than correct US findings, respectively. Acquired LNM were significantly more often localized in the region behind the SCM muscle and more often had solid US appearance in comparison to the congenital ones. Association of the clinical and US findings is very important in determining the most accurate preoperative diagnosis without exposing the children to unnecessary utilizing ionizing radiation or anesthesia. Although they are mostly benign, extreme caution is necessary due to malignancies which were found in 16.4% of all our patients.
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/1932-6203Test
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8دورية أكاديمية
المؤلفون: Sanja Stankovic, Milena Santric-Milicevic, Dejan Nikolic, Nenad Bjelica, Uros Babic, Ljiljana Rakic, Zorica Terzic-Supic, Jovana Todorovic
المصدر: Children, Vol 9, Iss 1, p 116 (2022)
مصطلحات موضوعية: fighting, bullying, school-age children, school, relations, professors, Pediatrics, RJ1-570
الوصف: Participating in physical fighting and bullying can be a cause of severe injury and death among school-age children. Research evidence can support school and health actors’ efforts to improve school-age children’s development and health capacity for life. The study aims to assess the prevalence of school-age children’s participation in fights and bullying in Serbia, and to examine the relevance of students’ socio-demographic characteristics and perceptions of school and relations with other students and professors for participation in fights and bullying. A secondary analysis is also performed on the original data of the 2017 HBSC study, which was conducted on 3267 students in a nationally representative sample of primary and high schools in Serbia. We sought to investigate the relationship between eight socio-demographic characteristics and nine school-related perceptions, with two outcome variables: taking part in fights and taking part in bullying, examined by using univariate and multivariate logistic regression. The main results show that 50.8% of boys and 17.1% of girls have taken part in fights, while 17.7% boys and 10.4% of girls have taken part in bullying. Students who felt a large and very large burden of school obligations were 1.43 times more likely to participate in bullying at least once, while they were 1.38 and 2.12 times more likely to participate in multiple fights and 4.04, 1.24, and 2.78 times more likely to participate multiple times in bullying. Multiple participation in fights and in bullying is significantly negatively associated with female gender, younger age years, good and very good perception of family financial status and quality of life, and positive perceptions of school and relations they have with other students and professors. Fights among school-age children are significantly positively associated with living with relatives/legal guardians and poor quality of life. In conclusion, the prevalence of participating in at least one fight/bullying is higher than in multiple fights/bullying. These associations suggest a necessity to enhance the monitoring and control of peer behavior among school-age children. The findings of the study imply key enablers of protection, such as building relationships based on team spirit and work, friendly behavior, empathy, and help, which should be included in the value system of school and family activities in programs to combat fights and bullying in school-age children.
وصف الملف: electronic resource
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9دورية أكاديمية
المؤلفون: Zorica J. TERZIC-SUPIC, Marina B. FISEKOVIC-KREMIC, Jovana TODOROVIC, Milena M. SANTRIC-MILICEVIC, Dejan M. NESIC, Goran Z. TRAJKOVIC
المصدر: Iranian Journal of Public Health, Vol 48, Iss 12 (2019)
مصطلحات موضوعية: Keywords Keywords, Public aspects of medicine, RA1-1270
الوصف: Abstracts Abstracts Abstracts
وصف الملف: electronic resource
العلاقة: https://ijph.tums.ac.ir/index.php/ijph/article/view/19091Test; https://doaj.org/toc/2251-6085Test; https://doaj.org/toc/2251-6093Test
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10دورية أكاديمية
المؤلفون: Ljiljana Markovic-Denic, Srboljub Milicevic, Jovana Todorovic, Vladimir Nikolic, Olivera Djuric, Vuk Marusic, Stefan Dugalic, Brankica Vasiljevic, Miroslava Gojnic-Dugalic
المصدر: Viruses, Vol 13, Iss 5, p 727 (2021)
مصطلحات موضوعية: human papillomavirus, vaccine, pregnancy, attitudes, knowledge, Microbiology, QR1-502
الوصف: We aimed to assess awareness, knowledge, and attitudes of healthy pregnant women towards human papillomavirus (HPV), to estimate factors associated with a positive attitude towards HPV immunization and to assess the uptake of the vaccine among their children. A cross-sectional study was conducted at the University Clinic of Gynecology and Obstetrics, Belgrade, Serbia among pregnant women attending their regular gynecological check-ups at the 12th gestational week. Knowledge about HPV and HPV vaccine was assessed using a specifically designed 12-item and 5-item questionnaires. Out of total 265 included women, 79.3% had heard of HPV, and 37.5% knew that HPV vaccine exists. HPV vaccine knowledge score was associated with higher odds for a positive attitude towards vaccination of both female (OR = 4.10, 95% CI 1.50–11.29) and male (OR = 3.71, 95% CI 1.52–9.01) child. The number of children (OR = 1.32, 95% CI 1.04–1.67) and high vaccine knowledge score (OR = 1.64 95% CI 1.13–2.39) were independent predictors associated with willingness to vaccinate child against HPV. The gynecologist was the preferable point of reference for information seeking about the HPV vaccine. Despite relatively high HPV awareness and knowledge among pregnant women in Serbia, about one-third of them are HPV vaccine aware, and are willing to vaccinate their children against HPV.
وصف الملف: electronic resource
النص الكامل