المؤلفون: Jina Han, Gawon Kim, Yeong Jun Ju, Soon Young Lee

المصدر: Kidney & Blood Pressure Research (2024)

مصطلحات موضوعية: Dermatology, RL1-803, Diseases of the circulatory (Cardiovascular) system, RC666-701, Diseases of the genitourinary system. Urology, RC870-923

الوصف: Backgrounds: The overall screening rate for complication of diabetes kidney disease is improving; however, regional variations are increasing. It is necessary to select regions vulnerable to change and understand their characteristics. Methods: Group-based trajectory analysis was performed to derive change patterns in the complication of diabetes kidney disease screening rate in 244 regions using Community Health Survey data between 2015 and 2019. ANOVA test was conducted to examine the differences in regional characteristics and CVD in each change pattern. Results: The change patterns in complication of diabetes kidney disease screening rate were classified into four groups: high and rapidly increasing (Group 1, 5.2%), steady high (Group 2, 8.2%), moderate and increasing (Group 3, 52.9%), and low and slightly increasing (Group 4, 23.8%). Group 4 had many rural areas and worse socioeconomic status, healthcare systems, health behaviors, and diabetes management, and these regions had higher CVD mortality rates. Conclusions: Regions where the screening for complication of diabetes kidney disease rate did not improve compared to other regions were vulnerable not only in socioeconomic status, healthcare system, and health behavior, but also in disease management. This suggests the need for local and environmental support, as well as aggressive health service interventions in relatively vulnerable areas.

وصف الملف: electronic resource

العلاقة: https://beta.karger.com/Article/FullText/538244Test; https://doaj.org/toc/1423-0143Test

الوصول الحر: https://doaj.org/article/daae170e0ef2497cb16716443da9b0feTest

المؤلفون: Xu Gao, Jina Han, Lixian Zhu, George-John E. Nychas, Yanwei Mao, Xiaoyin Yang, Yunge Liu, Xueqing Jiang, Yimin Zhang, Pengcheng Dong

المصدر: Foods, Vol 13, Iss 10, p 1533 (2024)

مصطلحات موضوعية: Salmonella typhimurium, two-component regulatory system, acid tolerance response, cross-protection, cationic antimicrobial peptide resistance mechanisms, Chemical technology, TP1-1185

الوصف: Acidic stress in beef cattle slaughtering abattoirs can induce the acid adaptation response of in-plant contaminated Salmonella. This may further lead to multiple resistance responses threatening public health. Therefore, the acid, heat, osmotic and antibiotic resistances of Salmonella typhimurium (ATCC14028) were evaluated after a 90 min adaption in a pH = 5.4 “mild acid” Luria–Bertani medium. Differences in such resistances were also determined between the ∆phoP mutant and wild-type Salmonella strains to confirm the contribution of the PhoP/PhoQ system. The transcriptomic differences between the acid-adapted and ∆phoP strain were compared to explore the role of the PhoP/Q two-component system in regulating multi-stress resistance. Acid adaptation was found to increase the viability of Salmonella to lethal acid, heat and hyperosmotic treatments. In particular, acid adaptation significantly increased the resistance of Salmonella typhimurium to Polymyxin B, and such resistance can last for 21 days when the adapted strain was stored in meat extract medium at 4 °C. Transcriptomics analysis revealed 178 up-regulated and 274 down-regulated genes in the ∆phoP strain. The Salmonella infection, cationic antimicrobial peptide (CAMP) resistance, quorum sensing and two-component system pathways were down-regulated, while the bacterial tricarboxylic acid cycle pathways were up-regulated. Transcriptomics and RT-qPCR analyses revealed that the deletion of the phoP gene resulted in the down-regulation of the expression of genes related to lipid A modification and efflux pumps. These changes in the gene expression result in the change in net negative charge and the mobility of the cell membrane, resulting in enhanced CAMP resistance. The confirmation of multiple stress resistance under acid adaptation and the transcriptomic study in the current study may provide valuable information for the control of multiple stress resistance and meat safety.

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2304-8158/13/10/1533Test; https://doaj.org/toc/2304-8158Test

الوصول الحر: https://doaj.org/article/9d97b391e73b49949e8fadd32e930e5bTest

المؤلفون: Jina Han, Hye Jin Baek, Eunbi Noh, Kyuhyun Yoon, Jung Ae Kim, Sukhyun Ryu, Kay O Lee, No Yai Park, Eunok Jung, Sangil Kim, Hyukmin Lee, Yoo-Sung Hwang, Jaehun Jung, Hun Jae Lee, Sung-il Cho, Sangcheol Oh, Migyeong Kim, Chang-Mo Oh, Byengchul Yu, Young-Seoub Hong, Keonyeop Kim, Sunjae Jung, Mi Ah Han, Moo-Sik Lee, Jung-Jeung Lee, Young Hwangbo, Hyeon Woo Yim, Yu-Mi Kim, Joongyub Lee, Weon-Young Lee, Jae-Hyun Park, Sungsoo Oh, Heui Sug Jo, Hyeongsu Kim, Gilwon Kang, Hae-Sung Nam, Ju-Hyung Lee, Gyung-Jae Oh, Min-Ho Shin, Soyeon Ryu, Tae-Yoon Hwang, Soon-Woo Park, Sang Kyu Kim, Roma Seol, Ki-Soo Park, Su Young Kim, Jun-wook Kwon, Sung Soon Kim, Byoungguk Kim, June-Woo Lee, Eun Young Jang, Ah-Ra Kim, Jeonghyun Nam, The Korea Community Health Survey Group, Soon Young Lee, Dong-Hyun Kim

المصدر: Epidemiology and Health, Vol 45 (2023)

مصطلحات موضوعية: covid-19, seroepidemiologic studies, antibody, community health survey, sampling studies, Medicine

الوصف: OBJECTIVES We estimated the population prevalence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including unreported infections, through a Korea Seroprevalence Study of Monitoring of SARS-CoV-2 Antibody Retention and Transmission (K-SEROSMART) in 258 communities throughout Korea. METHODS In August 2022, a survey was conducted among 10,000 household members aged 5 years and older, in households selected through two stage probability random sampling. During face-to-face household interviews, participants self-reported their health status, COVID-19 diagnosis and vaccination history, and general characteristics. Subsequently, participants visited a community health center or medical clinic for blood sampling. Blood samples were analyzed for the presence of antibodies to spike proteins (anti-S) and antibodies to nucleocapsid proteins (anti-N) SARS-CoV-2 proteins using an electrochemiluminescence immunoassay. To estimate the population prevalence, the PROC SURVEYMEANS statistical procedure was employed, with weighting to reflect demographic data from July 2022. RESULTS In total, 9,945 individuals from 5,041 households were surveyed across 258 communities, representing all basic local governments in Korea. The overall population-adjusted prevalence rates of anti-S and anti-N were 97.6% and 57.1%, respectively. Since the Korea Disease Control and Prevention Agency has reported a cumulative incidence of confirmed cases of 37.8% through July 31, 2022, the proportion of unreported infections among all COVID-19 infection was suggested to be 33.9%. CONCLUSIONS The K-SEROSMART represents the first nationwide, community-based seroepidemiologic survey of COVID-19, confirming that most individuals possess antibodies to SARS-CoV-2 and that a significant number of unreported cases existed. Furthermore, this study lays the foundation for a surveillance system to continuously monitor transmission at the community level and the response to COVID-19.

وصف الملف: electronic resource

العلاقة: http://www.e-epih.org/upload/pdf/epih-45-e2023075.pdfTest; https://doaj.org/toc/2092-7193Test

الوصول الحر: https://doaj.org/article/e8c6309c2a90412e9edcb730f0684676Test

المؤلفون: Jina Han, Yeong Jun Ju, Soon Young Lee

المصدر: Epidemiology and Health, Vol 45 (2023)

مصطلحات موضوعية: sedentary behavior, exercise, cardiovascular disease, korean health panel survey, trends, Medicine

الوصف: OBJECTIVES To identify the distinct trajectories of sedentary behavior (SB) and explore whether reduced cardiovascular disease (CVD) risk was associated with a distinct trajectory of physical activity (PA). METHODS We analyzed data from 6,425 people who participated in the Korean Health Panel Survey over a period of 10 years. The participants’ self-reported SB and PA were assessed annually, and trajectory groups were identified using a group-based trajectory model for longitudinal data analysis. Logistic regression analysis was performed to assess the association between CVD risk (10-year cumulative incidence) and the trajectories of SB and PA. The adjusted variables included socio-demographic factors, the predisposing diseases of CVD, and baseline health behaviors. RESULTS Trajectory analysis identified 4 SB trajectory groups: SB group 1 (low and slightly increasing trend, 53.1%), SB group 2 (high and rapidly decreasing trend, 14.7%), SB group 3 (high and slightly decreasing trend, 9.9%), and SB group 4 (low and rapidly increasing trend, 22.2%). The 3 PA trajectory groups were PA group 1 (moderate and slightly decreasing trend, 32.1%), PA group 2 (low and slightly decreasing trend, 57.3%), and PA group 3 (maintained inactivity, 10.7%). By the 10-year follow-up, 577 cases of incident CVD had occurred. We also noted a 50% reduction in the risk of CVD when SB group 4 was accompanied by PA group 1 (odds ratio, 0.50; 95% confidence interval, 0.28 to 0.90). CONCLUSIONS Despite increased time spent in SB, maintaining PA about 2 days to 3 days per week reduced the occurrence of CVD.

وصف الملف: electronic resource

العلاقة: http://www.e-epih.org/upload/pdf/epih-45-e2023028.pdfTest; https://doaj.org/toc/2092-7193Test

الوصول الحر: https://doaj.org/article/832b38da53634c34b65caa587e38d3ffTest

المؤلفون: Shuang Wu, Jina Han, Rongrong Liang, Pengcheng Dong, Lixian Zhu, David L. Hopkins, Yimin Zhang, Xin Luo

المصدر: Asian-Australasian Journal of Animal Sciences, Vol 33, Iss 12, Pp 1999-2007 (2020)

مصطلحات موضوعية: beef color, dark cutting, oxygen consumption, metmyoglobin reducing activity, ultimate ph, Animal culture, SF1-1100, Animal biochemistry, QP501-801

الوصف: Objective This study was aimed to investigate the muscle-specific beef color stability at normal and high ultimate pHs. Methods The impact of muscle (Longissimus lumborum [LL] vs psoas major [PM]) and pH (normal ultimate pH [Np] vs high pH dark cutting beef [Hp]) on color stability, indicated by basic color traits, metmyoglobin reducing activity (MRA) and oxygen consumption (OC), as well as the lipid oxidation, were determined over 7 days of display at 4°C. Results Hp-LL had the highest pH (6.92), followed by Hp-PM (6.01), Np-PM (5.76), and Np-LL (5.52). Hp-LL had increased (p

وصف الملف: electronic resource

العلاقة: http://www.ajas.info/upload/pdf/ajas-19-0943.pdfTest; https://doaj.org/toc/1011-2367Test; https://doaj.org/toc/1976-5517Test

الوصول الحر: https://doaj.org/article/0c7b3f699be647ef8aaee131dfe86605Test

المؤلفون: Yunge Liu, Lina Wu, Jina Han, Pengcheng Dong, Xin Luo, Yimin Zhang, Lixian Zhu

المصدر: Frontiers in Microbiology, Vol 11 (2021)

مصطلحات موضوعية: Listeria monocytogenes, anti-biofilm mechanism, gene expression, quorum sensing, microscopic examinations, Microbiology, QR1-502

الوصف: The aim of this study was to assess the efficacy of four natural antimicrobial compounds (cinnamaldehyde, eugenol, resveratrol and thymoquinone) plus a control chemical disinfectant (sodium hypochlorite) in inhibiting biofilm formation by Listeria monocytogenes CMCC54004 (Lm 54004) at a minimum inhibitory concentration (MIC) and sub-MICs. Crystal violet staining assay and microscopic examination were employed to investigate anti-biofilm effects of the evaluated compounds, and a real-time PCR assay was used to investigate the expression of critical genes by Lm 54004 biofilm. The results showed that five antimicrobial compounds inhibited Lm 54004 biofilm formation in a dose dependent way. Specifically, cinnamaldehyde and resveratrol showed better anti-biofilm effects at 1/4 × MIC, while sodium hypochlorite exhibited the lowest inhibitory rates. A swimming assay confirmed that natural compounds at sub-MICs suppressed Lm 54004 motility to a low degree. Supporting these findings, expression analysis showed that all four natural compounds at 1/4 × MIC significantly down-regulated quorum sensing genes (agrA, agrC, and agrD) rather than suppressing the motility- and flagella-associated genes (degU, motB, and flaA). This study revealed that sub-MICs of natural antimicrobial compounds reduced biofilm formation by suppressing the quorum sensing system rather than by inhibiting flagella formation.

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fmicb.2020.617473/fullTest; https://doaj.org/toc/1664-302XTest

الوصول الحر: https://doaj.org/article/9368e3fd170242e3a3cc9d1f909ee56fTest

المؤلفون: Jina Han, 韓 冀娜

المصدر: アジア教育 / The Japanese Journal of Studies on Asian Education. 2017, 11:15

المؤلفون: Jinhyun, Kim, Jina, Han

المصدر: Ethnicity & Health. :1-15

مصطلحات موضوعية: Cultural Studies, Arts and Humanities (miscellaneous), Public Health, Environmental and Occupational Health

الوصف: Patient navigation has served as a useful intervention to reduce cancer disparities among diverse ethnic groups. Previous studies have consistently shown the effectiveness of patient navigation in reducing cancer disparities for ethnic minorities; however, few studies have been conducted for cancer screening behaviors focusing on the Asian population. This study aims to identify the overall effectiveness of patient navigation in cancer screening behaviors among Asian Americans through meta-analyses. In addition, this study examines the moderating effects of the type of cancers on cancer screening behaviors.For data analyses, we selected 15 studies through a systematic review and meta-analyses, searching the databases of PubMed, Web of Science, Embase, Scopus, and Cochrane Library. Random-effects models were used for meta-analyses.The results showed that Asian Americans who received patient navigation were more likely to participate in cancer screening behaviors than those who did not receive patient navigation regardless of the type of cancer. Publication bias was tested using a funnel plot, meta-regression, and Failsafe-N. No notable publication bias was found.This study can provide comprehensive evidence regarding the overall effectiveness of patient navigation in cancer screening behaviors of Asian Americans.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e85778df514722f22720eeafa3c4faTest
https://doi.org/10.1080/13557858.2022.2122409Test

المؤلفون: Jina Han, Yeong Jun Ju, Soon Young Lee

المصدر: Epidemiology and Health.

مصطلحات موضوعية: General Medicine

الوصف: Objectives: To identify the distinct trajectories of sedentary behavior (SB) and explore whether reduced cardiovascular disease (CVD) risk was associated with a distinct trajectory of physical activity (PA). Methods: We analyzed data from 6,425 people who participated in the Korean Health Panel Survey over a period of 10 years. The participants’ self-reported SB and PA were assessed annually, and trajectory groups were identified using a group-based trajectory model for longitudinal data analysis. Logistic regression analysis was performed to assess the association between CVD risk (10-year cumulative incidence) and the trajectories of SB and PA. The adjusted variables included sociodemographic factors, the predisposing diseases of CVD, and baseline health behaviors. Results: Trajectory analysis identified 4 SB trajectory groups: SB group 1 (low and slightly increasing trend, 53.1%), SB group 2 (high and rapidly decreasing trend, 14.7%), SB group 3 (high and slightly decreasing trend, 9.9%), and SB group 4 (low and rapidly increasing trend, 22.2%). The 3 PA trajectory groups were PA group 1 (moderate and slightly decreasing trend, 32.1%), PA group 2 (low and slightly decreasing trend, 57.3%), and PA group 3 (maintained inactivity, 10.7%). By the 10-year follow-up, 577 cases of incident CVD had occurred. We also noted a 50% reduction in the risk of CVD when SB group 4 was accompanied by PA group 1 (odds ratio, 0.50; 95% confidence interval, 0.28–0.90).Conclusions: Despite increased time spent in SB, maintaining PA approximately 3 days a week reduced the occurrence of CVD.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2fff21c78cd6043c811dd5415ddd9466Test
https://doi.org/10.4178/epih.e2023028Test

المؤلفون: Jina Han, Xu Gao, Xin Luo, Lixian Zhu, Yimin Zhang, Pengcheng Dong

المصدر: Food Microbiology. 112:104244

مصطلحات موضوعية: Microbiology, Food Science

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::71cfb0a73a471c45a83a39c58544f582Test
https://doi.org/10.1016/j.fm.2023.104244Test