المؤلفون: Yan, Hong-Sen, Bi, Zhong-Tian, Zhou, Bo, Wan, Xiao-Qin, Zhang, Jiao-Jun, Wang, Guo-Biao

المصدر: Kybernetes, 2022, Vol. 52, Issue 10, pp. 4257-4271.

الوصول الحر: http://www.emeraldinsight.com/doi/10.1108/K-09-2021-0882Test

المؤلفون: Jiao-Jun Zhang, Yong-Hua Zhou, Qi-Ming Sun

المصدر: IEEE Access, Vol 12, Pp 4618-4630 (2024)

مصطلحات موضوعية: High-order nonlinear systems, nonlinear parameterization, switched systems, prescribed-time control, unmodeled dynamics, input quantization, Electrical engineering. Electronics. Nuclear engineering, TK1-9971

الوصف: This study focuses on the adaptive prescribed-time neural control for a class of high-order switched systems with nonlinear parameterization in presence of unmodeled dynamics and quantized input. Different from the existing results on finite-time control on basis of adding a power integrator technique, the controller construction and stability analysis are simplified, and the tracking error remains within a set range over any prescribed time. Under the frame of backstepping design, a state feedback controller is designed. During the controller design procedure, Radial basis function (RBF) neural networks with minimal learning parameters are employed to identify the unknown compounded nonlinear functions, and the control input is quantized. Based on Lyapunov stability theory, the closed-loop system’s signals are all assured to be semi-globally uniformly bounded (SGUB), and the tracking error is kept inside a prescribed zone at a finite time. Finally, a numerical simulation is provided to demonstrate the viability and efficacy of the control strategy.

وصف الملف: electronic resource

العلاقة: https://ieeexplore.ieee.org/document/10378685Test/; https://doaj.org/toc/2169-3536Test

الوصول الحر: https://doaj.org/article/a005f9e69f124dc1ae2dc2163ee41e3eTest

المؤلفون: XU Jishuang, JIAO Jun, LI Miao, LI Hualong, YANG Xuanjiang, LIU Xianwang, GUO Panpan, MA Zhirun

المصدر: 智慧农业, Vol 5, Iss 4, Pp 127-136 (2023)

مصطلحات موضوعية: a* algorithm, transport robots, bezier curve, path planning, fuzzy pid, sick and dead animal, Agriculture (General), S1-972, Technology (General), T1-995

الوصف: [Objective]A key challenge for the harmless treatment center of sick and dead animal is to prevent secondary environmental pollution, especially during the process of transporting the animals from cold storage to intelligent treatment facilities. In order to solve this problem and achieve the intelligent equipment process of transporting sick and dead animal from storage cold storage to harmless treatment equipment in the harmless treatment center, it is necessary to conduct in-depth research on the key technical problems of path planning and autonomous walking of transport robots.[Methods]A * algorithm is mainly adopted for the robot path planning algorithm for indoor environments, but traditional A * algorithms have some problems, such as having many inflection points, poor smoothness, long calculation time, and many traversal nodes. In order to solve these problems, a path planning method for the harmless treatment of diseased and dead animal using transport robots based on the improved A algorithm was constructed, as well as a motion control method based on fuzzy proportional integral differential (PID). The Manhattan distance method was used to replace the heuristic function of the traditional A * algorithm, improving the efficiency of calculating the distance between the starting and ending points in the path planning process. Referring to the actual location of the harmless treatment site for sick and dead animal, vector cross product calculation was performed based on the vector from the starting point to the target point and the vector from the current position to the endpoint target. Additional values were added and dynamic adjustments were implemented, thereby changing the value of the heuristic function. In order to further improve the efficiency of path planning and reduce the search for nodes in the planning process, a method of adding function weights to the heuristic function was studied based on the actual situation on site, to change the weights according to different paths. When the current location node was relatively open, the search efficiency was improved by increasing the weight. When encountering situations such as corners, the weight was reduced to improve the credibility of the path. By improving the heuristic function, a driving path from the starting point to the endpoint was quickly obtained, but the resulting path was not smooth enough. Meanwhile, during the tracking process, the robot needs to accelerate and decelerate frequently to adapt to the path, resulting in energy loss. Therefore, according to the different inflection points and control points of the path, different orders of Bessel functions were introduced to smooth the planning process for the path, in order to achieve practical application results. By analyzing the kinematics of robot, the differential motion method of the track type was clarified. On this basis, a walking control algorithm for the robot based on fuzzy PID control was studied and proposed. Based on the actual operation status of the robot, the fuzzy rule conditions were recorded into a fuzzy control rule table, achieving online identification of the characteristic parameters of the robot and adjusting the angular velocity deviation of robot. When the robot controller received a fuzzy PID control signal, the angular velocity output from the control signal was converted into a motor rotation signal, which changed the motor speed on both sides of the robot to achieve differential control and adjust the steering of the robot.[Results and Discussions]Simulation experiments were conducted using the constructed environmental map obtained, verifying the effectiveness of the path planning method for the harmless treatment of sick and dead animal using the improved A algorithm. The comparative experiments between traditional A * algorithm and improved algorithm were conducted. The experimental results showed that the average traversal nodes of the improved A * algorithm decreased from 3 067 to 1 968, and the average time of the algorithm decreased from 20.34 s to 7.26 s. Through on-site experiments, the effectiveness and reliability of the algorithm were further verified. Different colors were used to identify the planned paths, and optimization comparison experiments were conducted on large angle inflection points, U-shaped inflection points, and continuous inflection points in the paths, verifying the optimization effect of the Bessel function on path smoothness. The experimental results showed that the path optimized by the Bessel function was smoother and more suitable for the walking of robot in practical scenarios. Fuzzy PID path tracking experiment results showed that the loading truck can stay close to the original route during both straight and turning driving, demonstrating the good effect of fuzzy PID on path tracking. Further experiments were conducted on the harmless treatment center to verify the effectiveness and practical application of the improved algorithm. Based on the path planning algorithm, the driving path of robot was quickly planned, and the fuzzy PID control algorithm was combined to accurately output the angular velocity, driving the robot to move. The transport robots quickly realized the planning of the transportation path, and during the driving process, could always be close to the established path, and the deviation error was maintained within a controllable range.[Conclusions]A path planning method for the harmless treatment of sick and dead animal using an transport robots based on an improved A * algorithm combined with a fuzzy PID motion control was proposed in this study. This method could effectively shorten the path planning time, reduce traversal nodes, and improve the efficiency and smoothness of path planning.

وصف الملف: electronic resource

العلاقة: http://www.smartag.net.cn/CN/abstract/abstract22200.shtmlTest; https://doaj.org/toc/2096-8094Test

الوصول الحر: https://doaj.org/article/589ac308e8de485fb41380f322784732Test

المؤلفون: Zhang, Jiao-Jun, Zhou, Yong-Hua, Sun, Qi-Ming

المساهمون: Science Foundation of Zhejiang Sci-Tech University, Zhejiang Provincial Natural Science Foundation of China, Education Informatization Research Project of Jiangsu Province

المصدر: IEEE Access ; volume 12, page 4618-4630 ; ISSN 2169-3536

مصطلحات موضوعية: General Engineering, General Materials Science, General Computer Science, Electrical and Electronic Engineering

الإتاحة: https://doi.org/10.1109/access.2023.3348455Test
http://xplorestaging.ieee.org/ielx7/6287639/10380310/10378685.pdf?arnumber=10378685Test

المؤلفون: Wu, Siyu, Jiao, Jun, Yue, Xiaoyu, Wang, Yaping

المساهمون: Qilu Hospital of Shandong University

المصدر: Frontiers in Public Health ; volume 12 ; ISSN 2296-2565

مصطلحات موضوعية: Public Health, Environmental and Occupational Health

الوصف: Background Cervical cancer is the fourth highest incidence of malignancy in the world and a common cause of cancer death in women. We assessed the trends of incidence and mortality and disability-adjusted life year (DALY) in China, England and India from 1990 to 2030. Method Data were obtained from the Global Burden of Disease (GBD) database. We collected the number and rate of incidence, death and DALY from 1990 to 2019 and calculated the estimated annual percentage change (EAPC). Further analysis was carried out by ages and years. We also collected attributable risk factors to cervical cancer. Finally, we utilized the Bayesian Age-Period-Cohort (BAPC) model to forecast trends in the rate of age-standardized incidence (ASIR) and age-standardized death (ASDR) the for the next decade. Result Globally, the incidence of cervical cancer cases increased from 335,641.56 in 1990 to 565,540.89 in 2019. In 2019, the ASIR and ASDR of cervical cancer were higher than those of India but lower than those of England. Furthermore, unsafe sex and smoking emerge as prominent risk factors for cervical cancer. Over the next decade, ASIR and ASDR are expected to decline in China and England, while India’s ASIR is still on an upward trend and ASDR is on a downward trend. Conclusion The epidemiological data of cervical cancer in these three countries reflects the influence of different stages of development and healthcare systems. Trends over the next decade suggest that China and India still face a huge burden of cervical cancer. When England has made significant progress, China and India need to take more measures to improve the prevention and control of cervical cancer.

الإتاحة: https://doi.org/10.3389/fpubh.2024.1358433Test

المؤلفون: Liu, Meiheng, Shi, Leiyu, Yang, Manfei, Jiao, Jun, Yang, Junyan, Ma, Mengyuan, Xie, Wanzhen, Sun, Gang

المساهمون: Natural Science Foundation of Guangdong Province

المصدر: Frontiers in Public Health ; volume 12 ; ISSN 2296-2565

مصطلحات موضوعية: Public Health, Environmental and Occupational Health

الوصف: Objective The purpose of this study is to provide experience and evidence support for countries to deal with similar public health emergencies such as COVID-19 by comparing and analyzing the measures taken by six countries in epidemic prevention and control. Methods This study extracted public data on COVID-19 from the official website of various countries and used ecological comparative research methods to compare the specific situation of indicators such as daily tests per thousand people, stringency index, and total vaccinations per hundred people in countries. Results The cumulative death toll in China, Germany and Australia was significantly lower than that in the United States, South Africa and Italy. Expanding the scale of testing has helped control the spread of the epidemic to some extent. When the epidemic situation is severe, the stringency index increases, and when the epidemic situation tends to ease, the stringency index decreases. Increased vaccination rates, while helping to build an immune barrier, still need to be used in conjunction with non-drug interventions. Conclusion The implementation of non-drug interventions and vaccine measures greatly affected the epidemic prevention and control effect. In responding to public health emergencies such as the COVID-19 epidemic, countries should draw on international experience, closely align with their national conditions, follow the laws of epidemiology, actively take non-drug intervention measures, and vigorously promote vaccine research and development and vaccination.

الإتاحة: https://doi.org/10.3389/fpubh.2024.1277457Test

المؤلفون: Wan, Weiqiang, Zhang, Shan, Zhao, Mingliang, OuYang, Xuan, Yu, Yonghui, Xiong, Xiaolu, Zhao, Ning, Jiao, Jun

المصدر: Frontiers in Cellular and Infection Microbiology ; volume 13 ; ISSN 2235-2988

مصطلحات موضوعية: Infectious Diseases, Microbiology (medical), Immunology, Microbiology

الوصف: Coxiella burnetii is an obligate intracellular bacterium that causes Q fever, a zoonotic disease typically manifests as a severe flu-illness. After invading into the host cells, C. burnetii delivers effectors to regulate the vesicle trafficking and fusion events to form a large and mature Coxiella -containing vacuole (CCV), providing sufficient space and nutrition for its intracellular growth and proliferation. Lysosomal trafficking regulator (LYST) is a member of the Beige and Chediak-Higashi syndrome (BEACH) family, which regulates the transport of vesicles to lysosomes and regulates TLR signaling pathway, but the effect of LYST on C. burnetii infection is unclear. In this study, a series of experiments has been conducted to investigate the influence of LYST on intracellular growth of C. burnetii . Our results showed that lyst transcription was up-regulated in the host cells after C. burnetii infection, but there is no significant change in lyst expression level after infection with the Dot/Icm type IV secretion system (T4SS) mutant strain, while CCVs expansion and significantly increasing load of C. burnetii appeared in the host cells with a silenced lyst gene, suggesting LYST inhibits the intracellular proliferation of C. burnetii by reducing CCVs size. Then, the size of CCVs and the load of C. burnetii in the HeLa cells pretreated with E-64d were significantly decreased. In addition, the level of iNOS was decreased significantly in LYST knockout THP-1 cells, which was conducive to the intracellular replication of C. burnetii . This data is consistent with the phenotype of L-NMMA-treated THP-1 cells infected with C. burnetii . Our results revealed that the upregulation of lyst transcription after infection is due to effector secretion of C. burnetii and LYST inhibit the intracellular replication of C. burnetii by reducing the size of CCVs and inducing nos2 expression.

الإتاحة: https://doi.org/10.3389/fcimb.2023.1336600Test

المؤلفون: Cheng, Ruxi, Zhou, Chunyu, Zhao, Mingliang, Zhang, Shan, Wan, Weiqiang, Yu, Yonghui, Wen, Bohai, Jiao, Jun, Xiong, Xiaolu, Xu, Qin, OuYang, Xuan

المساهمون: Atack, John M., Beijing Municipal Natural Science Foundation, State Key Laboratory of Pathogen and Biosecurity

المصدر: Microbiology Spectrum ; volume 12, issue 4 ; ISSN 2165-0497

الوصف: Rickettsia rickettsii ( R. rickettsii ), the causative agent of Rocky Mountain spotted fever (RMSF), is the most pathogenic member among Rickettsia spp. Previous studies have shown that tripartite motif-containing 56 (TRIM56) E3 ligase-induced ubiquitination of STING is important for cytosolic DNA sensing and type I interferon production to induce anti-DNA viral immunity, but whether it affects intracellular replication of R. rickettsii remains uncharacterized. Here, we investigated the effect of TRIM56 on HeLa and THP-1 cells infected with R. rickettsii . We found that the expression of TRIM56 was upregulated in the R. rickettsii -infected cells, and the overexpression of TRIM56 inhibited the intracellular replication of R. rickettsii , while R. rickettsii replication was enhanced in the TRIM56-silenced host cells with the reduced phosphorylation of IRF3 and STING and the increased production of interferon-β. In addition, the mutation of the TRIM56 E3 ligase catalytic site impairs the inhibitory function against R. rickettsii in HeLa cells. Altogether, our study discovers that TRIM56 is a host restriction factor of R. rickettsii by regulating the cGAS-STING-mediated signaling pathway. This study gives new evidence for the role of TRIM56 in the innate immune response against intracellular bacterial infection and provides new therapeutic targets for RMSF. IMPORTANCE Given that Rickettsia rickettsii ( R. rickettsii ) is the most pathogenic member within the Rickettsia genus and serves as the causative agent of Rocky Mountain spotted fever, there is a growing need to explore host targets. In this study, we examined the impact of host TRIM56 on R. rickettsii infection in HeLa and THP-1 cells. We observed a significant upregulation of TRIM56 expression in R. rickettsii -infected cells. Remarkably, the overexpression of TRIM56 inhibited the intracellular replication of R. rickettsii , while silencing TRIM56 enhanced bacterial replication accompanied by reduced phosphorylation of IRF3 and STING, along with ...

الإتاحة: https://doi.org/10.1128/spectrum.03695-23Test

المؤلفون: Jiao, Jun, 1957

مرشدي الرسالة: Seraphin, Supapan

مصطلحات موضوعية: Physics, Electricity and Magnetism., Physics, Condensed Matter., Engineering, Materials Science.

الوصف: This study was undertaken to gain a greater understanding of the growth mechanism of carbon nanoclusters. A set of carbon nanocluster samples prepared by three different methods and under different conditions was characterized with respect to morphology, structure, composition, and related properties. Electron microscopy characterization techniques were used to identify these features. The carbon nanoclusters prepared by conventional arc discharge, modified arc discharge, and catalytic CO disproportionation appear quite different on the surface, but have features in common that this study emphasizes. For the understanding of the growth mechanisms of carbon nanoclusters of different morphologies, the dependence of growth features on the major processing parameters--carbon supply and carbon activity, reaction temperature, gas type and partial pressure, composition and materials involved--was interpreted systematically in a comparative manner. For the encapsulation of foreign materials into carbon cages, the ratio of the supply of carbon and encapsulants, the dimensions and configurations of the electrodes, the flow of a buffer gas across the carbon source, the nature and surface area of materials to be encapsulated or acting as catalyst were recognized as the basic components of a process that lead to properties of as-made materials such as the size distribution of the clusters, the degree of the carbonization of the encapsulants, and the predominant presence of certain morphologies. Regarding the comparison of the structural stability of different morphologies, the results of the post deposition treatments such as elevated high temperature annealing, nitric acid erosion, and electron beam bombardment provide further insight into the properties of this novel family of materials. Operating in certain domains of the parameter space, carbon-coated ferromagnetic nanoparticles, single-walled nanotubes, cylindrical multi-walled nanotubes, and conical fish-bone filaments were produced and comparatively characterized. A tentative discussion with the aim of confirming, expanding or modifying some growth models that have emerged from the work of the past was given in this dissertation. It is expected that this broad-based comparative study will advance the understanding of the growth mechanism to a point where some of the technological promise of the carbon nanoclusters may be realized.

الإتاحة: http://hdl.handle.net/10150/282358Test

المؤلفون: Liu, Maomao, Wei, Sichen, Shahi, Simran, Jaiswal, Hemendra Nath, Paletti, Paolo, Fathipour, Sara, Remskar, Maja, Jiao, Jun, Hwang, Wansik, Yao, Fei, Li, Huamin

مصطلحات موضوعية: Condensed Matter - Materials Science

الوصف: High contact resistance is one of the primary concerns for electronic device applications of two-dimensional (2D) layered semiconductors. Here, we explore the enhanced carrier transport through metal-semiconductor interfaces in WS2 field effect transistors (FETs) by introducing a typical transition metal, Cu, with two different doping strategies: (i) a "generalized" Cu doping by using randomly distributed Cu atoms along the channel and (ii) a "localized" Cu doping by adapting an ultrathin Cu layer at the metal-semiconductor interface. Compared to the pristine WS2 FETs, both the generalized Cu atomic dopant and localized Cu contact decoration can provide a Schottky-to-Ohmic contact transition owing to the reduced contact resistances by 1 - 3 orders of magnitude, and consequently elevate electron mobilities by 5 - 7 times higher. Our work demonstrates that the introduction of transition metal can be an efficient and reliable technique to enhance the carrier transport and device performance in 2D TMD FETs.
Comment: Under review

الوصول الحر: http://arxiv.org/abs/2001.05105Test