المؤلفون: John P. Bilezikian, Shonni J. Silverberg, Francisco Bandeira, Filomena Cetani, Manju Chandran, Natalie E. Cusano, Peter R. Ebeling, Anna Maria Formenti, Morten Frost, Jessica Gosnell, E. Michael Lewiecki, Frederick R. Singer, Neil Gittoes, Aliya A. Khan, Claudio Marcocci, Lars Rejnmark, Zhikang Ye, Gordon Guyatt, John T. Potts

المصدر: Bilezikian, J P, Silverberg, S J, Bandeira, F, Cetani, F, Chandran, M, Cusano, N E, Ebeling, P R, Formenti, A M, Frost, M, Gosnell, J, Lewiecki, E M, Singer, F R, Gittoes, N, Khan, A A, Marcocci, C, Rejnmark, L, Ye, Z, Guyatt, G & Potts, J T 2022, ' Management of Primary Hyperparathyroidism ', Journal of Bone and Mineral Research, vol. 37, no. 11, pp. 2391-2403 . https://doi.org/10.1002/jbmr.4682Test

مصطلحات موضوعية: PARATHYROID-RELATED DISORDERS, Parathyroid Hormone, Endocrinology, Diabetes and Metabolism, CELL/TISSUE SIGNALING—ENDOCRINE PATHWAYS, Humans, Orthopedics and Sports Medicine, DISORDERS OF CALCIUM/PHOSPHATE METABOLISM, Hyperparathyroidism, Primary, PTH/VIT D/FGF23, CLINICAL TRIALS, Systematic Reviews as Topic

الوصف: Since the last international guidelines were published in 2014 on the evaluation and management of primary hyperparathyroidism (PHPT), new information has become available with regard to evaluation, diagnosis, epidemiology, genetics, classical and nonclassical manifestations, surgical and nonsurgical approaches, and natural history. To provide the most current summary of these developments, an international group, consisting of over 50 experts in these various aspects of PHPT, was convened. This paper provides the results of the task force that was assigned to review the information on the management of PHPT. For this task force on the management of PHPT, two questions were the subject of systematic reviews using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) methodology. The full report addressing surgical and nonsurgical management of PHPT, utilizing the GRADE methodology, is published separately in this series. In this report, we summarize the results of that methodological review and expand them to encompass a much larger body of new knowledge that did not specifically fit the criteria of the GRADE methodology. Together, both the systematic and narrative reviews of the literature, summarized in this paper, give the most complete information available to date. A panel of experts then considered the last set of international guidelines in light of the newer data and assessed the need for their revision. This report provides the evidentiary background to the guidelines report. In that report, evidence from all task forces is synthesized into a summary statement and revised guidelines for the evaluation and management of PHPT. © 2022 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR).

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3de10ac5569127a210ad328c5ea970Test
https://pure.au.dk/portal/da/publications/management-of-primary-hyperparathyroidismTest(30ecef19-eee4-4f33-8931-95c07b1dd8b6).html

المؤلفون: null John P Bilezikian, null Aliya A Khan, null Shonni J Silverberg, null Ghada El‐Hajj Fuleihan, null Claudio Marcocci, null Salvatore Minisola, null Nancy Perrier, null Antonio Sitges‐Serra, null Rajesh V Thakker, null Gordon Guyatt, null Michael Mannstadt, null John T Potts, null Bart L Clarke, null Maria Luisa Brandi, null Andrew Arnold, null Zhanna Balaya, null Lorenz Hofbauer, null Karl Insogna, null Andre Lacroix, null Uri A. Liberman, null Andrea Palermo, null Rene Rizzoli, null Robert Wermers, null Fadil M. Hannan, null Jessica Pepe, null Cristiana Cipriani, null Richard Eastell, null Jian‐min Liu, null Ambrish Mithal, null Carolina A. Moreira, null Munro Peacock, null Barbara Silva, null Marcella Walker, null Marlene Chakhtoura, null Marian Schini, null Ola El Zein, null Martin Almquist, null Leonardo C. B. Farias, null Quan‐Yang Duh, null Brian H. Lang, null Virginia LiVolsi, null Mark Swayk, null Menno R. Vriens, null Thinh Vu, null Michael W. Yeh, null Randy Yeh, null Omar Shariq, null Leyre L. Poch, null Francisco Bandeira, null Filomena Cetani, null Manju Chandran, null Natalie E. Cusano, null Peter R. Ebeling, null Jessica Gosnell, null E. Michael Lewiecki, null Frederick R. Singer, null Morten Frost, null Anna Maria Formenti, null Tatiana Karonova, null Neil Gittoes, null Lars Rejnmark, null the International Workshop on Primary Hyperparathyroidism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565d68fd9f5143b76897681df39f1eefTest
https://doi.org/10.1002/jbmr.4677/v3/response1Test

المؤلفون: null John P. Bilezikian, null Shonni J. Silverberg, null Francisco Bandeira, null Filomena Cetani, null Manju Chandran, null Natalie E. Cusano, null Peter R. Ebeling, null Anna Maria Formenti, null Morten Frost, null Jessica Gosnell, null E. Michael Lewiecki, null Frederick R. Singer, null Neil Gittoes, null Aliya A. Khan, null Claudio Marcocci, null Lars Rejnmark, null Zhikang Ye, null Gordon Guyatt, null John T. Potts

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb69bdebbeba181d5d98330abd35f36Test
https://doi.org/10.1002/jbmr.4682/v3/response1Test

المؤلفون: Patricia C. Conroy, Timothy Ullmann, Stephanie Davis, Jessica Gosnell, Quan-Yang Duh

المصدر: VideoEndocrinology. 9:67-68

مصطلحات موضوعية: General Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8844822d36a14776a7464532a1d65cd5Test
https://doi.org/10.1089/ve.2022.0018Test

المؤلفون: Marlon A. Guerrero, Sheila Lindsay, Insoo Suh, Menno R. Vriens, Elham Khanafshar, Wen T. Shen, Jessica Gosnell, Electron Kebebew, Quan-Yang Duh, Orlo H. Clark

المصدر: Journal of Cancer, Vol 2, Iss 1, Pp 200-205 (2011)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

الوصف: Background: Medullary thyroid cancer (MTC) commonly presents with lymph node (LN) metastases, and has a worse prognosis than papillary thyroid cancer (PTC). Tumor size and LN involvement have been shown to affect stage of disease; however, to our knowledge, ours is the first study that attempts to correlate anterior neck pain on presentation with the extent of disease.Methods: We performed a retrospective review of patients with MTC who underwent an operation from February 1998 through December 2008. We compared the symptom of anterior neck pain with the pathologic extent of disease. Our control group comprised patients who underwent an operation for PTC. Analysis was performed using the Fisher's exact test and the Mann-Whitney test.Results: Of the 109 patients with MTC, 50 (46%) met our inclusion criteria. Of the 50 patients with MTC, 11 presented with neck pain, compared to 3 of the 50 patients with PTC (p = 0.041). Of those 11 patients, 9 (82%) had LN involvement on final pathology, as compared with 14 (36%) of the 39 without neck pain (p = 0.014). Of patients with neck pain, 18% were diagnosed at stage I to II and 82% at stage III to IV, compared to 64% at stage I to II and 36% at stage III to IV (p = 0.014).Conclusions: Our study demonstrates that more patients with MTC present with anterior neck pain than do patients with PTC and that patients with MTC and neck pain have an increased risk of LN metastases. The results of this study suggest that MTC patients, who present with concomitant neck pain, should undergo a total thyroidectomy, prophylactic bilateral central neck dissection, and ipsilateral lateral neck dissection.

وصف الملف: electronic resource

العلاقة: http://www.jcancer.org/v02p0200.htmTest; https://doaj.org/toc/1837-9664Test

الوصول الحر: https://doaj.org/article/7a7c16ff421048958b859d627efb5bd1Test

المؤلفون: Marlon A. Guerrero, Insoo Suh, Menno R. Vriens, Wen T. Shen, Jessica Gosnell, Electron Kebebew, Quan-Yang Duh, Orlo H. Clark

المصدر: Journal of Cancer, Vol 1, Iss 1, Pp 23-26 (2010)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

الوصف: Introduction: Hürthle cell carcinoma (HCC) is a rare tumor that tends to metastasize to the lymph nodes. Some studies have correlated size of Hürthle cell tumors with the risk of malignancy. Whether the size of HCC correlates with the risk of lymph node (LN) metastases, to our knowledge has not been addressed. Methods: A retrospective analysis was performed on all patients diagnosed with HCC on final pathology between 1997 and 2008. The tumor size and lymph node status was obtained for each patient. The data were analyzed utilizing Student's t-test and the Fisher's exact test to calculate the two-tailed p-value. Results: Out of 39 patients diagnosed with HCC 3(8%) had LN metastases; 1 had ipsilateral central LN metastasis and 2 had ipsilateral central and lateral LN metastasis. LN dissection was performed in patients with known metastasis (2 were evident on preoperative ultrasound and 1 intraoperatively). Patients with LN metastasis were older than those without (mean age: 86.7 and 56.4 years, respectively), had larger tumors (mean size: 6 and 4 cm) and were commonly male (2 of 3). No tumor < 5cm presented with lymph node involvement (3/15 with >5cm cancer had node metastasis, 0/24 with Conclusions: Similar to what has been found in patients with papillary thyroid cancer, older male patients with Hürthle cell carcinomas greater than 5cm are more likely to have lymph node metastasis. Our data suggest that these patients may benefit from a prophylactic ipsilateral central neck dissection at the time of their initial operation.

وصف الملف: electronic resource

العلاقة: http://www.jcancer.org/v01p0023.htmTest; https://doaj.org/toc/1837-9664Test

الوصول الحر: https://doaj.org/article/430f07cbcf0045408011b7bc55783c4fTest

المؤلفون: Sophia Hernandez, Siyou Song, Ogonna N. Nnamani Silva, Chelsie Anderson, Alexander S. Kim, Andre R. Campbell, Edward H. Kim, Adnan Alseidi, Elizabeth C. Wick, Julie Ann Sosa, Jessica Gosnell, Matthew Y.C. Lin, Sanziana A. Roman

المصدر: American journal of surgery, vol 224, iss 1 Pt B

مصطلحات موضوعية: Undergraduate, Knowledge gap, Medical student education, Students, Medical, Distance, Pandemic, Virtual education, Clinical Sciences, COVID-19, General Medicine, Education, Education, Distance, Knowledge, Clinical Research, Medical, General Surgery, Humans, Surgery, Curriculum, Students, Pandemics, Education, Medical, Undergraduate

الوصف: IntroductionThis study describes perceived knowledge gaps of third-year medical students after participating in a virtual surgical didactic rotation (EMLR) and shortened in-person surgery rotation during the COVID-19 Pandemic.MethodsOpen-ended and Likert questions were administered at the end of the virtual rotation and inperson-surgical rotation to medical students. Three blinded coders identified themes by semantic analysis.Results82 students (51% of all MS3s) participated in the EMLR. Semantic analysis revealed gaps in perioperative management (Post-EMLR:18.4%, Post-Inpatient:26.5%), anatomy (Post-EMLR:8.2%, PostInpatient:26.5%). and surgical skills (Post-EMLR: 43.0%, Post-Inpatient: 44.1%). Students also described gaps related to OR etiquette (Post-EMLR: 12.2%, Post-Inpatient: 8.8%) and team dynamics/the hidden curriculum (Post- Inpatient:26.6%). There was a significant improvement in perceived confidence to perform inpatient tasks after completing the inpatient clinical experience (p≤0.01).ConclusionVirtual interactive didactics for cognitive skills development cannot replace a full clinical surgical experience for third-year medical students. Future curricula should address perceived gaps.

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2df5016ac06df25fa934fb5ecffd34Test
https://pubmed.ncbi.nlm.nih.gov/35397920Test

المؤلفون: Yorke, April M., Caron, Jessica Gosnell, Pukys, Nina, Sternad, Emily, Grecol, Christina, Shermak, Carley

المصدر: Journal of Developmental and Physical Disabilities ; volume 33, issue 4, page 537-582 ; ISSN 1056-263X 1573-3580

مصطلحات موضوعية: Developmental and Educational Psychology, Physical Therapy, Sports Therapy and Rehabilitation

الإتاحة: https://doi.org/10.1007/s10882-020-09767-5Test

المؤلفون: Marlon A. Guerrero, Sheila Lindsay, Insoo Suh, Menno R. Vriens, Elham Khanafshar, Wen T. Shen, Jessica Gosnell, Electron Kebebew, Quan-yang Duh, Orlo H. Clark

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/6b/53/J_Cancer_2011_Apr_8_2_200-205.tar.gz

الوصف: © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License

وصف الملف: application/zip

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.291.5192Test

المؤلفون: Yorke, April M.¹ a.yorke@csuohio.edu, Caron, Jessica Gosnell², Pukys, Nina¹, Sternad, Emily¹, Grecol, Christina¹, Shermak, Carley¹

المصدر: Journal of Developmental & Physical Disabilities. Aug2021, Vol. 33 Issue 4, p537-582. 46p.

مصطلحات موضوعية: *FACILITATED communication, *SYSTEMATIC reviews

مستخلص: The acquisition of reading skills is vital for all individuals given the ubiquitous influence of reading on academic outcomes and quality of life. Individuals with complex communication needs, requiring the supports of augmentative and alternative communication (AAC), are often excluded from learning phonological approaches to literacy. Most literacy approaches require verbal production of speech sounds—which is particularly difficult for individuals with complex communication needs. However, despite challenges with spoken production of sounds, research has reported positive outcomes in participation in phonological interventions when they are adapted to meet the needs of individuals who use AAC. The purpose of the current study was to conduct a systematic review to evaluate the effectiveness of foundational reading interventions (specifically phonological awareness skills, letter-sound correspondences, and decoding interventions) designed to meet the needs of individuals who use AAC. Results indicate that large and very large effects are observed with adapted phonological interventions for individuals who use AAC. These results are consistent across ages, diagnoses, most interventionists, and phonological skills (e.g., decoding, letter-sounds, sound blending). Future research shifting away from very controlled settings with the researcher (to small and large group instruction, instruction by common service providers like teachers, or other types of instruction) may be particularly valuable to support access to, and implementation of, foundational reading interventions for individuals with complex communication needs who require AAC. [ABSTRACT FROM AUTHOR]