نتائج البحث

المساهمون: Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Pulmonary medicine, CCA - Cancer Treatment and quality of life

المصدر: Horn, L, Gettinger, S, Camidge, D R, Smit, E F, Janjigian, Y Y, Miller, V A, Pao, W, Freiwald, M, Fan, J, Wang, B, Chand, V K & Groen, H J M 2017, ' Continued use of afatinib with the addition of cetuximab after progression on afatinib in patients with EGFR mutation-positive non-small-cell lung cancer and acquired resistance to gefitinib or erlotinib ', Lung Cancer, vol. 113, pp. 51-58 . https://doi.org/10.1016/j.lungcan.2017.08.014Test
Lung Cancer, 113, 51-58. ELSEVIER IRELAND LTD
Lung Cancer, 113, 51-58. Elsevier Ireland Ltd

مصطلحات موضوعية: MECHANISM, Male, 0301 basic medicine, Oncology, Cancer Research, Lung Neoplasms, Afatinib, medicine.medical_treatment, MULTICENTER, Cetuximab, Kaplan-Meier Estimate, NSCLC, Cohort Studies, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, Medicine, Epidermal growth factor receptor, Aged, 80 and over, biology, Gefitinib, CHEMOTHERAPY, Middle Aged, OPEN-LABEL, Rash, ErbB Receptors, 030220 oncology & carcinogenesis, Disease Progression, Female, Erlotinib, medicine.symptom, medicine.drug, Adult, Diarrhea, Pulmonary and Respiratory Medicine, medicine.medical_specialty, EGFR, Phase Ib, RANDOMIZED PHASE-3 TRIAL, Erlotinib Hydrochloride, 03 medical and health sciences, HER2, Internal medicine, TYROSINE KINASE INHIBITORS, Humans, Lung cancer, neoplasms, Aged, Chemotherapy, business.industry, ADENOCARCINOMA, Exanthema, medicine.disease, respiratory tract diseases, 1ST-LINE TREATMENT, 030104 developmental biology, Drug Resistance, Neoplasm, Mutation, Quinazolines, biology.protein, GROWTH-FACTOR RECEPTOR, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28452e64bfdb20e6ab794abd7bf3038Test
https://doi.org/10.1016/j.lungcan.2017.08.014Test

45

Safety, pharmacokinetics, pharmacodynamics profiles and preliminary antitumor activity of phase 1b/2a study of NT-I7, a long-acting interleukin-7, plus pembrolizumab in patients with advanced solid tumors: The phase 1b data report

المؤلفون: Byung Ha Lee, Marya F. Chaney, Jean Fan, Ngocdiep T. Le, Aung Naing, Debashree Basudhar, Minal A. Barve, Cynthia Rajan, Cristina Laviada, Shubham Pant

المصدر: Journal of Clinical Oncology. 39:2594-2594

مصطلحات موضوعية: Antitumor activity, Cancer Research, business.industry, Interleukin, Pembrolizumab, Pharmacology, Peripheral blood, Long acting, Oncology, Pharmacokinetics, Pharmacodynamics, Medicine, In patient, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d3c87953853d88a815c59d2962019e71Test
https://doi.org/10.1200/jco.2021.39.15_suppl.2594Test

46

A phase I/II study to evaluate the safety and efficacy of a novel long-acting interleukin-7, NT-I7, for patients with newly diagnosed high-grade gliomas after chemoradiotherapy: The interim result of the phase I data

المؤلفون: Byung Ha Lee, Jian Campian, Jingqin Luo, Jiayi Huang, Gavin P. Dunn, Tanner M. Johanns, Se Hwan Yang, Puspanjali Bhatta, Jean Fan, George Ansstas, Albert H. Kim, Christopher Abraham, Ruth Katumba, Milan G. Chheda, Sunita Ranjitka, Chai Avvaru, Ngocdiep Le

المصدر: Journal of Clinical Oncology. 39:2040-2040

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Temozolomide, business.industry, medicine.medical_treatment, Interleukin, Newly diagnosed, Radiation therapy, Phase i ii, Long acting, Interim, Internal medicine, medicine, business, Chemoradiotherapy, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::40808852faef84610fc2481fe134e720Test
https://doi.org/10.1200/jco.2021.39.15_suppl.2040Test

47

Differential Pathway Analysis

المؤلفون: Jean, Fan

المصدر: Methods in molecular biology (Clifton, N.J.). 1935

مصطلحات موضوعية: Transcription, Genetic, Sequence Analysis, RNA, Gene Expression Profiling, Computational Biology, Gene Expression, Humans, Single-Cell Analysis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::3a5ac29592f8644f43446edf81be3168Test
https://pubmed.ncbi.nlm.nih.gov/30758822Test

48

A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion

المصدر: Cancer cell, vol 35, iss 2

مصطلحات موضوعية: 0301 basic medicine, Genome instability, Cancer Research, Lymphoma, Chronic lymphocytic leukemia, 129 Strain, Ataxia Telangiectasia Mutated Proteins, medicine.disease_cause, Inbred C57BL, murine model, Pathogenesis, Mice, 0302 clinical medicine, Piperidines, immune system diseases, hemic and lymphatic diseases, Neoplasms, Receptors, Tumor Cells, Cultured, Agammaglobulinaemia Tyrosine Kinase, 2.1 Biological and endogenous factors, Chronic, Aetiology, Cellular Senescence, Cancer, Mice, Knockout, Mutation, B-Lymphocytes, Cultured, Leukemia, biology, SF3B1, Hematology, Lymphocytic, Tumor Cells, Mutant Strains, medicine.anatomical_structure, Phenotype, Oncology, 030220 oncology & carcinogenesis, Antigen, RNA splicing, RNA Splicing Factors, Signal Transduction, Mice, 129 Strain, Knockout, Oncology and Carcinogenesis, Receptors, Antigen, B-Cell, Antineoplastic Agents, Article, Genomic Instability, BCR signaling, 03 medical and health sciences, Experimental, Rare Diseases, medicine, Genetics, Bruton's tyrosine kinase, Animals, Humans, Genetic Predisposition to Disease, Oncology & Carcinogenesis, neoplasms, Protein Kinase Inhibitors, B cell, Cell growth, Adenine, B-Cell, Neurosciences, Cell Biology, Neoplasms, Experimental, medicine.disease, Phosphoproteins, Leukemia, Lymphocytic, Chronic, B-Cell, Mice, Mutant Strains, Mice, Inbred C57BL, Alternative Splicing, 030104 developmental biology, Pyrimidines, ATM, Cancer research, biology.protein, Pyrazoles, Gene Deletion, CLL, DNA Damage

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a552fc6456f9a24e7ec4a5a8d172d93cTest
https://escholarship.org/uc/item/101965h5Test

49

Differential Pathway Analysis

المؤلفون: Jean Fan

المصدر: Methods in Molecular Biology ISBN: 9781493990566

مصطلحات موضوعية: 0303 health sciences, Computer science, 0206 medical engineering, Value (computer science), 02 engineering and technology, Computational biology, Pathway analysis, Set (abstract data type), 03 medical and health sciences, Overdispersion, Gene expression, Differential (infinitesimal), Cluster analysis, Gene, 020602 bioinformatics, 030304 developmental biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::20c8c8cb5a65114b6f3acb96db2567d5Test
https://doi.org/10.1007/978-1-4939-9057-3_7Test

50

Phase I dose-escalation trial of afatinib, an irreversible ErbB family blocker, in combination with gemcitabine or docetaxel in patients with relapsed or refractory solid tumors

المؤلفون: Jaafar Bennouna, Jean Fan, Nicolas Isambert, Sandrine Hiret, David Schnell, Hélène de Mont-Serrat, Mouna Sassi, Carlos Gomez-Roca, Jean-Pierre Delord

المساهمون: Institut de Cancérologie de l'Ouest [Angers/Nantes] (UNICANCER/ICO), UNICANCER, Centre Régional de Lutte contre le cancer Georges-François Leclerc [Dijon] (UNICANCER/CRLCC-CGFL), Institut Universitaire du Cancer de Toulouse - Oncopole (IUCT Oncopole - UMR 1037), CHU Toulouse [Toulouse]-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de pneumologie [Nantes], Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes), Boehringer Ingelheim France S.A.S., Institut Claudius Regaud, Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Investigational New Drugs
Investigational New Drugs, Springer Verlag, 2018, 36 (6), pp.1044-1059. ⟨10.1007/s10637-018-0601-1⟩

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Afatinib, medicine.medical_treatment, Docetaxel, Deoxycytidine, Cohort Studies, 0302 clinical medicine, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Solid tumors, Pharmacology (medical), Middle Aged, Rash, Progression-Free Survival, 3. Good health, ErbB Receptors, Treatment Outcome, Tolerability, Area Under Curve, 030220 oncology & carcinogenesis, Combination, Female, medicine.symptom, medicine.drug, medicine.medical_specialty, Maximum Tolerated Dose, Antineoplastic Agents, 03 medical and health sciences, Phase I, Internal medicine, medicine, Humans, neoplasms, Pharmacology, Chemotherapy, Dose-Response Relationship, Drug, business.industry, medicine.disease, Gemcitabine, Regimen, 030104 developmental biology, business, Febrile neutropenia, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6036dcafb030908058716a9686877fb5Test
https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01960201Test

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