-
51
المؤلفون: Daqing Sun, Xiao He, Jay P. Powers, Hua Tu, Xuelei Yan, Dustin McMinn, Peter Fan, Qiuping Ye, Min Jiang, Yosup Rew, Mario Monshouwer
المصدر: ACS medicinal chemistry letters. 5(11)
مصطلحات موضوعية: Covalent bond, Organic Chemistry, Drug Discovery, Reactive intermediate, Microsome, Metabolism, Plasma protein binding, Hydroxysteroid dehydrogenase, Pharmacology, Biology, Biochemistry, In vitro, Bioavailability
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b3d9a703715af6551fb93356b89a0cTest
https://pubmed.ncbi.nlm.nih.gov/25408839Test -
52
المؤلفون: Manmohan Reddy Leleti, Wan Hsin Lim, Fang-Fang Yin, Annette Becker, Ulrike Schindler, Juan C. Jaen, Yu Chen, Joanne B. Tan, Steve Young, Jay P. Powers, Matt J. Walters, Ada Chen
المصدر: Cancer Research. 77:2640-2640
مصطلحات موضوعية: 0301 basic medicine, Granzyme B production, Cancer Research, Chemistry, T cell, Purinergic signalling, Molecular biology, Adenosine, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Oncology, ATP hydrolysis, medicine, cAMP-dependent pathway, IL-2 receptor, Signal transduction, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b9cdbc3e886d66e627dd018a6f1d9fc9Test
https://doi.org/10.1158/1538-7445.am2017-2640Test -
53
المؤلفون: Manmohan Reddy Leleti, Annette Becker, Matt J. Walters, Juan C. Jaen, Fangfang Yi, Laurent Debien, Joanne B. Tan, Tim Park, Brandon Reid Rosen, Stefan Garrido-Shaqfeh, Jay P. Powers, Steve Young, Ehesan U. Sharif, Wan Hsin Lim
المصدر: Cancer Research. 77:4572-4572
مصطلحات موضوعية: 0301 basic medicine, Agonist, Cancer Research, Forskolin, biology, medicine.drug_class, CD3, Antagonist, CD28, Pharmacology, Adenosine, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Oncology, chemistry, 030220 oncology & carcinogenesis, medicine, biology.protein, IL-2 receptor, Receptor, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1009b25a68339b6a7bd4fe65fa7b1ca1Test
https://doi.org/10.1158/1538-7445.am2017-4572Test -
54
المؤلفون: Joanne Bl Tan, Steve Young, Erick Allen Lindsey, Juan C. Jaen, Jay P. Powers, Ada Chen, Manmohan Reddy Leleti, Annette Becker, Jaroslaw Kalisiak, Ulrike Schindler
المصدر: Cancer Immunology Research. 5:B46-B46
مصطلحات موضوعية: Adenosine monophosphate, Granzyme B production, Cancer Research, T cell, Immunology, Biology, Molecular biology, Granzyme B, chemistry.chemical_compound, medicine.anatomical_structure, Biochemistry, chemistry, medicine, Interleukin 12, Cytotoxic T cell, IL-2 receptor, CD8
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::60f0658fa830f33b445458d0e8ed52bfTest
https://doi.org/10.1158/2326-6074.tumimm16-b46Test -
55
المؤلفون: Ulrike Schindler, Steve Young, Jay P. Powers, J. Jaen, E. Sharif, J. Tan, H. Sexton, D. Miles, T. Park, A. Chen, Manmohan Reddy Leleti
المصدر: European Journal of Cancer. 69:S96
مصطلحات موضوعية: Cancer Research, Immune system, Oncology, Chemistry, Immunology, Cancer research, Cytotoxic T cell, Tumor growth, Ecto nucleotidases, Small molecule
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1718d742fd3e7b0b0ae0a3204a69a861Test
https://doi.org/10.1016/s0959-8049Test(16)32885-4 -
56
المؤلفون: Manmohan Reddy Leleti, Juan C. Jaen, Ulrike Schindler, Jarek Kalisiak, Steve Young, Jay P. Powers, Shin Heng Chiou, Laurent Debien, Ada Chen, Joanne Bl Tan
المصدر: Cancer Immunology Research. 4:PR10-PR10
مصطلحات موضوعية: 0301 basic medicine, Granzyme B production, Cancer Research, T cell, Immunology, CD28, Biology, Molecular biology, Granzyme B, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, medicine, Cytotoxic T cell, IL-2 receptor, Cell activation, CD8
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::277ac4041d7522197e13366d8b3715ddTest
https://doi.org/10.1158/2326-6066.imm2016-pr10Test -
57
المؤلفون: Yu Wang, Zheng Wei, Juan C. Jaen, Trageen Baumgart, Linda S. Ertl, Robert D. Berahovich, Ruiping Zhao, Daniel J. Dairaghi, Jay P. Powers, Antoni Krasinski, Timothy J. Sullivan, Solomon Ungashe, Chia-Lin Tsou, Thomas J. Schall, Andrew M. K. Pennell, Zhenhua Miao, Israel F. Charo, Bin N. Zhao, Landin Boring, Lisa Seitz
المصدر: American journal of physiology. Renal physiology. 305(9)
مصطلحات موضوعية: Male, medicine.medical_specialty, CCR2, Chemokine, Physiology, Receptors, CCR2, Transgene, Mice, Transgenic, Kidney, Kidney Function Tests, Mice, Insulin resistance, Internal medicine, medicine, Animals, Humans, Diabetic Nephropathies, Gene Knock-In Techniques, Receptor, Glycemic, Sulfonamides, biology, HEK 293 cells, Articles, medicine.disease, Mice, Inbred C57BL, medicine.anatomical_structure, Endocrinology, HEK293 Cells, Hyperglycemia, biology.protein, Insulin Resistance
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a479a469f2d8832cd050d0daa8ccbd72Test
https://pubmed.ncbi.nlm.nih.gov/23986513Test -
58
المؤلفون: Yosup Rew, Steve Schneider, Peter Yakowec, Lisa Julian, Jude Canon, Alexander M. Long, Xuelei Yan, Julio C. Medina, Xin Huang, Jonathan D. Oliner, Hilary Plake Beck, Felix Gonzalez-Lopez de Turiso, Dongyin Yu, Shou-Hua Xiao, Ada Chen, Mei-Chu Lo, Xiaoning Zhao, Anne Y. Saiki, David Chow, Michael D. Bartberger, Jing Zhou, Qiuping Ye, Tiffany L. Correll, Daqing Sun, Frank Kayser, Steven H. Olson, Jay P. Powers, Tao Osgood, Dustin McMinn, Paul L. Shaffer
المصدر: Journal of medicinal chemistry. 56(10)
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Morpholines, Mice, Nude, Antineoplastic Agents, Crystallography, X-Ray, Cocrystal, Mice, Structure-Activity Relationship, Piperidines, In vivo, Drug Discovery, Animals, Humans, IC50, Messenger RNA, Crystallography, biology, Chemistry, Circular Dichroism, Rational design, Proto-Oncogene Proteins c-mdm2, Stereoisomerism, Small molecule, Xenograft Model Antitumor Assays, Pharmacodynamics, Drug Design, biology.protein, Molecular Medicine, Mdm2, Female, Indicators and Reagents, Tumor Suppressor Protein p53
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b2b421ad8ad7c0f32d30da3d1a9de9Test
https://pubmed.ncbi.nlm.nih.gov/23597064Test -
59
المؤلفون: Juan C. Jaen, Yu Wang, Trageen Baumgart, Robert D. Berahovich, Daniel J. Dairaghi, Jay P. Powers, Antoni Krasinski, Timothy J. Sullivan, Linda S. Ertl, Zhenhua Miao, Matthew J. Walters, Thomas J. Schall, Lisa Seitz, Bin N. Zhao
المصدر: Metabolism: clinical and experimental. 62(11)
مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Receptors, CCR2, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Adipose tissue, Type 2 diabetes, Biology, Diet, High-Fat, Diabetes Mellitus, Experimental, chemistry.chemical_compound, Mice, Endocrinology, Insulin resistance, Glycosuria, Internal medicine, Insulin-Secreting Cells, medicine, Animals, Hypoglycemic Agents, Insulin, Obesity, Triglycerides, Inflammation, geography, geography.geographical_feature_category, Glycogen, Adiponectin, Dose-Response Relationship, Drug, Macrophages, Islet, medicine.disease, Mice, Inbred C57BL, chemistry, Adipose Tissue, Diabetes Mellitus, Type 2, Liver, Glucose-6-Phosphatase, Insulin Resistance, Diet-induced obese, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783f377f1c174082a1990232a96067dbTest
https://pubmed.ncbi.nlm.nih.gov/23953944Test -
60
المؤلفون: Juan C. Jaen, Penglie Zhang, Daniel J. Dairaghi, Jay P. Powers
مصطلحات موضوعية: CCR1, Chemokine, Bone disease, biology, business.industry, Multiple sclerosis, medicine.disease, Bioinformatics, Clinical trial, Rheumatoid arthritis, Immunology, medicine, biology.protein, business, Multiple myeloma
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::df7d218724a4c3004b2d56a871bc86f7Test
https://doi.org/10.1016/b978-0-12-417150-3.00010-7Test