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11
المؤلفون: Brandon Reid Rosen, Manmohan Reddy Leleti, Ada Chen, Sharon Zhao, Jenna L. Jeffrey, Norbert Sträter, Eric T. Newcomb, Jay P. Powers, Kenneth V. Lawson, Lijuan Fu, Dillon H. Miles, Uli Schindler, Wade Berry, Stephen W Young, Tim Park, Emma Scaletti, Lixia Jin, Joanne B.L. Tan, Ehesan U. Sharif, Laurent Debien, Erick Allen Lindsey, Jaroslaw Kalisiak, Susanne Moschütz, Matthew J. Walters, Guifen Xu, Nigel Walker
المصدر: Journal of Medicinal Chemistry. 63:11448-11468
مصطلحات موضوعية: Models, Molecular, T cell, CD8-Positive T-Lymphocytes, Pharmacology, GPI-Linked Proteins, 01 natural sciences, Small Molecule Libraries, Mice, Structure-Activity Relationship, 03 medical and health sciences, Immune system, Pharmacokinetics, Drug Discovery, medicine, Extracellular, Animals, Humans, Structure–activity relationship, 5'-Nucleotidase, 030304 developmental biology, 0303 health sciences, Tumor microenvironment, Binding Sites, Chemistry, Catabolism, Haplorhini, Adenosine, Rats, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, medicine.anatomical_structure, Leukocytes, Mononuclear, Molecular Medicine, Protein Binding, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb2a8967687083bf528bd8c33e2866fTest
https://doi.org/10.1021/acs.jmedchem.0c00525Test -
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المؤلفون: Jenna L. Jeffrey, Laurent Debien, Dillon H. Miles, Manmohan Reddy Leleti, Brandon Reid Rosen, Jay P. Powers, Ehesan U. Sharif
المصدر: Organic Process Research & Development. 24:1254-1261
مصطلحات موضوعية: Chemistry, medicine.drug_class, Organic Chemistry, Convergent synthesis, medicine, Antagonist, Physical and Theoretical Chemistry, DUAL (cognitive architecture), Pharmacology, Receptor, Receptor antagonist
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::89f6c9ebef3f0788b33a57e7900a3115Test
https://doi.org/10.1021/acs.oprd.0c00124Test -
13
المؤلفون: Stephen W Young, Debashis Mandal, Sharon Zhao, Susanne Moschütz, Ada Chen, Elaine Ginn, Lixia Jin, Samuel L Drew, Nigel Walker, Erick Allen Lindsey, Jay P. Powers, Kenneth V. Lawson, Xuelei Yan, Anh Tran, Rhiannon Thomas-Tran, Amber Pham, Manmohan Reddy Leleti, Jenna L. Jeffrey, Steven D. Jacob, Norbert Sträter, Joel W. Beatty, Jeremy Fournier, Laurent Debien
المصدر: Journal of Medicinal Chemistry. 63:3935-3955
مصطلحات موضوعية: Membrane permeability, Stereochemistry, CHO Cells, Crystallography, X-Ray, GPI-Linked Proteins, Binding, Competitive, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Cricetulus, Cricetinae, Drug Discovery, medicine, Animals, Humans, Nucleotide, 5'-Nucleotidase, Cells, Cultured, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Chemistry, Triazoles, Purinergic signalling, Adenosine, Small molecule, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Benzonitrile, Enzyme, Hepatocytes, Molecular Medicine, Nucleoside, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb1d479ddd330a628c6dc7fec984840Test
https://doi.org/10.1021/acs.jmedchem.9b01713Test -
14
المؤلفون: Jean Chan, Lixia Jin, Kelsey Sivick Gauthier, Stephen W Young, Matthew J. Walters, Balint Gal, Anh Tran, Kenneth V. Lawson, Elaine Ginn, Manmohan Reddy Leleti, Jennie Au, Soonweng Cho, Dana Piovesan, Xiaoning Zhao, Akshata Udyavar, Jay P. Powers, Ada Chen, Cesar Meleza, Brandon Reid Rosen, Samuel L Drew
المصدر: Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
مصطلحات موضوعية: Tumor microenvironment, Stromal cell, Hypoxia-inducible factors, Angiogenesis, Chemistry, Cancer cell, Cancer research, Gene silencing, Cytokine secretion, Gene signature, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce023df8e6af859a49a662f82516a0b5Test
https://doi.org/10.1136/jitc-2020-sitc2020.0583Test -
15
المؤلفون: Kenneth V. Lawson, Jenna L. Jeffrey, Jay P. Powers
المصدر: Journal of medicinal chemistry. 63(22)
مصطلحات موضوعية: Drug, media_common.quotation_subject, Antineoplastic Agents, GPI-Linked Proteins, 01 natural sciences, Protein Structure, Secondary, 03 medical and health sciences, Drug Delivery Systems, Drug Discovery, medicine, Extracellular, Humans, Ectonucleotidase, Nucleotide, Enzyme Inhibitors, 5'-Nucleotidase, 030304 developmental biology, media_common, chemistry.chemical_classification, 0303 health sciences, Tumor microenvironment, Nucleotides, Apyrase, Metabolism, Adenosine, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, Cancer research, Molecular Medicine, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6d695fef9e6b1a7341abf8389d4b35Test
https://pubmed.ncbi.nlm.nih.gov/32786396Test -
16
المؤلفون: Susan L. Paprcka, Subhasree Sridhar, Irene M. Luu, Salema Jafri, Dillon H. Miles, Suan Liu, Ruben Flores, Shiwei Qu, Manjunath Lamani, Sriivas Paladugu, Cesar Meleza, James Wu, Hema Singh, Yu Chen, Sean Cho, Akshata Udyavar, Angelo Kaplan, Enzo Stargnaro, Xiaoning Zhao, Lixia Jin, Manmohan R. Leleti, Stephen W. Young, Jay P. Powers, Matthew J. Walters, Ester Fernandez-Salas
المصدر: Molecular Cancer Therapeutics. 20:P253-P253
مصطلحات موضوعية: Cancer Research, Oncology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1f736b4410c621a6d4569da191903c72Test
https://doi.org/10.1158/1535-7163.targ-21-p253Test -
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المؤلفون: Kelsey E. Sivick Gauthier, Dana Piovesan, Soonweng Cho, Kenneth V. Lawson, Patrick G. Schweickert, Alejandra Lopez, Suan Liu, Timothy Park, Artur Mailyan, Jeremy T. A. Fournier, Joel W. Beatty, Samuel L. Drew, Jarek Kalisiak, Balint Gal, Guillaume Mata, Zhang Wang, Brandon R. Rosen, Clayton Hardman, Matthaw P. Epplin, Kai Yu, Karl T. Haelsig, Lixia Jin, Elaine Ginn, Jennie Au, Cesar A. Meleza, Joel Tencer, Amber Pham, Hyock J. Kwon, Stephen W. Young, Manmohan Leleti, Jay P. Powers, Matthew J. Walters
المصدر: Molecular Cancer Therapeutics. 20:P206-P206
مصطلحات موضوعية: Cancer Research, Oncology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3dcad50485d58db7e77ba50a6a9d4ed2Test
https://doi.org/10.1158/1535-7163.targ-21-p206Test -
18
المؤلفون: Stephen W. Young, Guillaume Mata, Joel W. Beatty, Matthew J. Walters, Kelsey Sivick Gauthier, Jeremy Fournier, Jennifer Au, Jay P. Powers, Dana Piovesan, Artur K. Mailyan, Kenneth V. Lawson, Manmohan Reddy Leleti, Elaine Ginn, Jarek Kalisiak, Xuelei Yan, Balint Gal, Zhang Wang, Lixia Jin, Samuel L Drew, Cesar Meleza
المصدر: Cancer Research. 81:1206-1206
مصطلحات موضوعية: Cancer Research, Oncology, Hypoxia-inducible factors, Chemistry, Cell biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2d5fa52383b1811c1aeb7706770bc35eTest
https://doi.org/10.1158/1538-7445.am2021-1206Test -
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المؤلفون: D. Miles, C.N. Foley, Jay P. Powers, Matthew J. Walters, R. Grange, Manmohan Reddy Leleti, Y. Chen, X. Zhao, Lixia Jin, Steve Young, S.L. Paprcka
المصدر: European Journal of Cancer. 138:S38-S39
مصطلحات موضوعية: Cancer Research, Oncology, AXL receptor tyrosine kinase, Chemistry, Cancer research, Cancer therapy
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::265fc6b03c800e13c140e414312889caTest
https://doi.org/10.1016/s0959-8049Test(20)31175-8 -
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المؤلفون: Gerhard Arold, Joanne B.L. Tan, Manmohan Reddy Leleti, Jenna L. Jeffrey, Devika Ashok, Renger G. Tiessen, Aimee Rieger, Lisa Seitz, Matthew J. Walters, Jay P. Powers, Joyson Joseph Karakunnel, Lixia Jin
المصدر: Investigational new drugs. 37(4)
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Adolescent, Administration, Oral, Pharmacology, CD8-Positive T-Lymphocytes, Adenosine receptor antagonist, 03 medical and health sciences, Food-Drug Interactions, Young Adult, 0302 clinical medicine, Pharmacokinetics, Double-Blind Method, Medicine, Humans, Pharmacology (medical), Receptor, Cyclic AMP Response Element-Binding Protein, business.industry, Antagonist, Middle Aged, Adenosine receptor, Adenosine, Healthy Volunteers, 030104 developmental biology, Oncology, Tolerability, Purinergic P1 Receptor Antagonists, 030220 oncology & carcinogenesis, Pharmacodynamics, Female, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac27a0011b98f6e166801e63c4ccdaeTest
https://pubmed.ncbi.nlm.nih.gov/30569245Test