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1دورية أكاديمية
المؤلفون: Seon Ui Lee, Subeen Hong, Sae Kyung Choi, Su Mi Kim, Jae Eun Shin, Ki Cheol Kil, Yeon Hee Kim, Jeong Ha Wie, Yun Sung Jo, Hyun Sun Ko
المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
الوصف: Abstract Clinical implication of a single abnormal value (SAV) in the 100 g oral glucose tolerance test during pregnancy has not been established. We aimed to evaluate the risk of postpartum type 2 diabetes mellitus (T2DM) and investigate adverse pregnancy outcomes in women with SAV, using a retrospective database, from seven medical centers of Korea. Based on the Carpenter-Coustan criteria using two-step approach, pregnancy and postpartum outcomes were compared, among normoglycemic, SAV, and gestational diabetes mellitus (GDM) groups. Among 9353 women, 342 (3.66%) and 418(4.47%) women were included in SAV and GDM groups, respectively. SAV and GDM groups showed significantly higher rates of postpartum T2DM than normoglycemic group (7.60%, 14.83%, and 1.82%, respectively, p
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2045-2322Test
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2دورية أكاديمية
المؤلفون: Seon Ui Lee, Jae Young Park, Subeen Hong, Jeong Ha Wie, Jae Eun Shin, Sae Kyung Choi, Woo Jeng Kim, Yeon Hee Kim, Yun Sung Jo, In Yang Park, Kicheol Kil, Hyun Sun Ko
المصدر: BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-9 (2024)
مصطلحات موضوعية: Pregnancy, Stroke volume, Heart failure, Pregnancy outcome, Gynecology and obstetrics, RG1-991
الوصف: Abstract Background Although pregnancy-associated heart failure with preserved ejection fraction (HFpEF) is increasing and contributing to maternal morbidity, little is known about its impact on pregnancy. We examined the risk factors for and adverse pregnancy outcomes of HFpEF in pregnant women. Methods We conducted a cross-sectional analysis of pregnancy-related hospitalizations from 2009 to 2020 using the perinatal database of seven multicenters. Cases of HFpEF were identified using the International Classification of Diseases and echocardiography findings. The patients were categorized into the HFpEF and control groups. Risk factors were evaluated using multivariate logistic regression analysis to generate odds ratios (OR) and 95% confidence intervals (CI). Furthermore, adjusted associations between HFpEF and adverse pregnancy outcomes were determined. Risk scores for the stratification of women at a high risk of HFpEF were calculated using a statistical scoring model. Results Of the 34,392 women identified, 258 (0.76%) were included in the HFpEF group. In multivariate analysis, HFpEF was significantly associated with old maternal age (OR, 1.04; 95% CI 1.02–1.07), multiple pregnancy (OR, 2.22; 95% CI 1.53–3.23), rheumatic disease (OR, 2.56; 95% CI 1.54–4.26), pregnancy induce hypertension (OR 6.02; 95% CI 3.61–10.05), preeclampsia (OR 24.66; 95% CI 18.61–32.66), eclampsia or superimposed preeclampsia (OR 32.74; 95% CI 21.60–49.64) and transfusion in previous pregnancy (OR 3.89; 95% CI 1.89–8.01). A scoring model to predict HFpEF with those factors achieved an area under the curve of 0.78 at cutoff value of 3. Women with HFpEF also had increased odds ratios of intensive care unit admission during the perinatal period (odds ratio, 5.98; 95% confidence interval, 4.36–8.21) and of postpartum hemorrhage (odds ratio, 5.98; 95% confidence interval, 2.02–3.64). Conclusions Pregnancy-associated HFpEF is associated with adverse pregnancy outcomes. A scoring model may contribute to screening HFpEF using echocardiography and preparing adverse pregnancy outcomes.
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/1471-2393Test
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3دورية أكاديمية
المؤلفون: Subeen Hong, Byung Soo Kang, Oyoung Kim, Sangeun Won, Hyeon Soo Kim, Jeong Ha Wie, Jae Eun Shin, Sae Kyung Choi, Yun Sung Jo, Yeon Hee Kim, Mihi Yang, Huiwon Kang, Dong-Wook Lee, In Yang Park, Joong Shin Park, Hyun Sun Ko
المصدر: Frontiers in Public Health, Vol 12 (2024)
مصطلحات موضوعية: endocrine disruptors, bisphenol-A, monoethyl phthalates, perfluorooctanoic acid, fetal growth restriction, placental insufficiency, Public aspects of medicine, RA1-1270
الوصف: Recent evidence has revealed associations between endocrine-disrupting chemicals (EDCs) and placental insufficiency due to altered placental growth, syncytialization, and trophoblast invasion. However, no epidemiologic study has reported associations between exposure to EDCs and asymmetric fetal growth restriction (FGR) caused by placenta insufficiency. The aim of this study was to evaluate the association between EDC exposure and asymmetric FGR. This was a prospective cohort study including women admitted for delivery to the Maternal Fetal Center at Seoul St. Mary’s Hospital between October 2021 and October 2022. Maternal urine and cord blood samples were collected, and the levels of bisphenol-A (BPA), monoethyl phthalates, and perfluorooctanoic acid in each specimen were analyzed. We investigated linear and non-linear associations between the levels of EDCs and fetal growth parameters, including the head circumference (HC)/abdominal circumference (AC) ratio as an asymmetric parameter. The levels of EDCs were compared between fetuses with and without asymmetric FGR. Of the EDCs, only the fetal levels of BPA showed a linear association with the HC/AC ratio after adjusting for confounding variables (β = 0.003, p
وصف الملف: electronic resource
العلاقة: https://www.frontiersin.org/articles/10.3389/fpubh.2024.1351786/fullTest; https://doaj.org/toc/2296-2565Test
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4دورية أكاديمية
المؤلفون: Byung Soo Kang, Seon Ui Lee, Subeen Hong, Sae Kyung Choi, Jae Eun Shin, Jeong Ha Wie, Yun Sung Jo, Yeon Hee Kim, Kicheol Kil, Yoo Hyun Chung, Kyunghoon Jung, Hanul Hong, In Yang Park, Hyun Sun Ko
المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
الوصف: Abstract This study developed a machine learning algorithm to predict gestational diabetes mellitus (GDM) using retrospective data from 34,387 pregnancies in multi-centers of South Korea. Variables were collected at baseline, E0 (until 10 weeks’ gestation), E1 (11–13 weeks’ gestation) and M1 (14–24 weeks’ gestation). The data set was randomly divided into training and test sets (7:3 ratio) to compare the performances of light gradient boosting machine (LGBM) and extreme gradient boosting (XGBoost) algorithms, with a full set of variables (original). A prediction model with the whole cohort achieved area under the receiver operating characteristics curve (AUC) and area under the precision-recall curve (AUPR) values of 0.711 and 0.246 at baseline, 0.720 and 0.256 at E0, 0.721 and 0.262 at E1, and 0.804 and 0.442 at M1, respectively. Then comparison of three models with different variable sets were performed: [a] variables from clinical guidelines; [b] selected variables from Shapley additive explanations (SHAP) values; and [c] Boruta algorithms. Based on model [c] with the least variables and similar or better performance than the other models, simple questionnaires were developed. The combined use of maternal factors and laboratory data could effectively predict individual risk of GDM using a machine learning model.
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2045-2322Test
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5دورية أكاديمية
المؤلفون: In Kee Kim, Jae Eun Shin, Min Jeong Kim, Ho Ra, Jiwon Baek
المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
الوصف: Abstract We sought to investigate changes in choroidal hemodynamics in preeclampsia according to presence of retinal change by quantitatively assessing choroidal vessels using optical coherence tomography (OCT). This retrospective study included 106 eyes (of 53 patients) with preeclampsia, including 70 eyes without retinal change in patients with preeclampsia (Group A), 22 eyes with retinal change in patients with preeclampsia (Group B), and 14 eyes of normal pregnant women (controls). Subfoveal choroidal thickness (SFCT) was measured on OCT B-scan images, and choroidal vessel densities (CVDs) were calculated using binarized OCT B-scan and en face images. Their values were then correlated with clinical parameters associated with preeclampsia. SFCT was greater in Group B compared to Group A or controls (354.32 ± 65.13 vs. 288 ± 55.68 or 277.21 ± 50.08, both P
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2045-2322Test
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6دورية أكاديمية
المؤلفون: Sumin Kim, Jae Eun Shin
المصدر: Development Studies Research, Vol 9, Iss 1, Pp 206-218 (2022)
مصطلحات موضوعية: Public-private partnership, global CSR, development cooperation, the SDGs, ESG, South Korea, Economic growth, development, planning, HD72-88, Human settlements. Communities, HT51-65
الوصف: Public-private partnerships (PPPs) have become a widely recognized phenomenon in recent years, along with the rising emphasis on the private sector involvement in solving social problems both locally and globally. Against this backdrop, this study focuses on the expanded role of corporate social responsibility (CSR) in the Korean official development assistance framework. Private stakeholders’ expected roles and responsibilities in the area of international development cooperation have been augmented. The article explores the various factors driving this phenomenon from the perspectives of the public and private sectors. The case study of Korea International Cooperation Agency (KOICA) is carried out by analyzing the identified factors in the context of KOICA’s PPP strategy. The study found that the motives of the private sector to participate in KOICA’s global CSR program is less likely to be satisfied under the current arrangement whereas the public sector is highly motivated to attract and engage businesses in delivering PPP projects abroad. The study suggests policy implications such as incorporating non-financial performance indicators in evaluation criteria, resolving administrative challenges, and increasing the budget for PPP programs.
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2166-5095Test
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7دورية أكاديمية
المؤلفون: Geum Joon Cho, Ji Soo Um, Sa Jin Kim, Sung Won Han, Soo Bin Lee, Min-Jeong Oh, Jae Eun Shin
المصدر: BMC Pregnancy and Childbirth, Vol 22, Iss 1, Pp 1-8 (2022)
مصطلحات موضوعية: Cardiovascular disease, Low birth weight, Pregnancy complication, Preeclampsia, Preterm delivery, Stroke, Gynecology and obstetrics, RG1-991
الوصف: Abstract Background This study aimed to compare obstetric outcomes in Korean women with and without future cardiovascular disease (CVD) within 10 years after pregnancy, and assessed whether pregnancy complications are independent risk factors, and whether the combination of pregnancy complications has an additive function for risk factors for CVD. Methods This was a nationwide population-based study combining the database of the Korea National Health Insurance claims and National Health Screening Programs to assess preeclampsia, low birth weight (LBW), and preterm delivery as risk factors for CVD. Cox proportional hazards models was used to evaluate the risk of total CVD, ischemic heart disease (IHD), and stroke after the pregnancy complications, with adjustment for potential confounding variables. Results Women with CVD were likely to have a higher prevalence of pregnancy complications than women without CVD. The risk of total CVD was associated with preeclampsia (adjusted hazard ratio (HR), 1.60 [95% confidence interval (CI) 1.50–1.72]), LBW (1.20 [1.12–1.28]), and preterm delivery (1.32 [1.22–1.42]), after adjustment for confounders, including cardiovascular risk factors before pregnancy. The risk estimates of pregnancy complications for IHD were higher than those for stroke. In this study, the risk of total CVD was higher in the combined presence of preeclampsia and preterm delivery (2.23 [1.57–3.17] or all three complications (2.06 [1.76–2.40]), relative to no complications. The highest HR was noted in the risk of all pregnancy complications for IHD (2.39 [1.98–2.89]). Conclusion Preeclampsia, preterm delivery, and LBW were independently associated with CVD in young Korean women. In addition, the combination of pregnancy complications had less-than-additive effects on CVD incidence.
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/1471-2393Test
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8دورية أكاديمية
المؤلفون: Yun Sung Jo, Woo Jeng Kim, Sae Kyung Choi, Su Mi Kim, Jae Eun Shin, Ki Cheol Kil, Yeon Hee Kim, Jeong Ha Wie, Han Wool Kim, Subeen Hong, Hyun Sun Ko
المصدر: Life, Vol 13, Iss 6, p 1330 (2023)
مصطلحات موضوعية: pregnancy-associated hypertension, prediction, risk, scoring, Science
الوصف: This study aimed to develop an early pregnancy risk scoring model for pregnancy-associated hypertension (PAH) based on maternal pre-pregnancy characteristics, such as mean arterial pressure (MAP), pregnancy-associated plasma protein-A (PAPP-A) or neither. The perinatal databases of seven hospitals from January 2009 to December 2020 were randomly divided into a training set and a test set at a ratio of 70:30. The data of a total pregnant restricted population (women not taking aspirin during pregnancy) were analyzed separately. Three models (model 1, pre-pregnancy factors only; model 2, adding MAP; model 3, adding MAP and PAPP-A) and the American College of Obstetricians and Gynecologists (ACOG) risk factors model were compared. A total of 2840 (8.11%) and 1550 (3.3%) women subsequently developed PAH and preterm PAH, respectively. Performances of models 2 and 3 with areas under the curve (AUC) over 0.82 in both total population and restricted population were superior to those of model 1 (with AUCs of 0.75 and 0.748, respectively) and the ACOG risk model (with AUCs of 0.66 and 0.66) for predicting PAH and preterm PAH. The final scoring system with model 2 for predicting PAH and preterm PAH showed moderate to good performance (AUCs of 0.78 and 0.79, respectively) in the test set. “A risk scoring model for PAH and preterm PAH with pre-pregnancy factors and MAP showed moderate to high performances. Further prospective studies for validating this scoring model with biomarkers and uterine artery Doppler or without them might be required”.
وصف الملف: electronic resource
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9دورية أكاديمية
المؤلفون: Ji Young Kim, Dae Woo Lee, Min Jeong Kim, Jae Eun Shin, Yeun Joo Shin, Hae Nam Lee
المصدر: BMC Cancer, Vol 21, Iss 1, Pp 1-6 (2021)
مصطلحات موضوعية: KNHANES (Korea National Health and nutrition examination survey), Cervical cancer, Diabetes, BMI, Secondhand cigarette smoke, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: Abstract Background Human papilloma virus infection and tobacco smoking are the major risk factors for cervical cancer. There are limited studies searching other risk factors for cervical cancer and the results are not consistent. This study investigated the relations between cervical cancer and possible risk factors, including secondhand cigarette smoke exposure, diabetes, body mass index (BMI), and work schedule. Methods In this cross-sectional study, 29,557 women completed a cervical cancer questionnaire and were selected using 2010–2018 data from the Korea National Health and Nutrition Examination Survey. Details in secondhand smoke exposure, diabetes, BMI, and work schedule were assessed with participants’ health interviews and health-related surveys. Results Two hundred sixty-two women (0.89%) in the sample were diagnosed with cervical cancer. Domestic secondhand smoke exposure, diabetes, and high BMI significantly increased cervical cancer risk. Respective odds ratios and 95% confidence intervals were: 1.547 (1.042–2.297), 2.156 (1.535–3.027), and 1.036 (1.006–1.067). Weekly work hours, and work schedule were not significantly related to cervical cancer incidence. Conclusion Among Korean women, passive exposure to cigarette smoke at home, diabetes, and high BMI increase risk for cervical cancer.
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/1471-2407Test
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10دورية أكاديمية
المؤلفون: Haeil Park, Dae Woo Lee, Min Jeong Kim, Jae Eun Shin, Hae Nam Lee
المصدر: Taiwanese Journal of Obstetrics & Gynecology, Vol 60, Iss 1, Pp 36-40 (2021)
مصطلحات موضوعية: The risk of ovarian malignancy algorithm (ROMA), Ovarian cancer, Predictive value of tests, Triiodothyronine, Gynecology and obstetrics, RG1-991
الوصف: Objective: We investigated factors that could cause false-positive results when using the risk of ovarian malignancy algorithm (ROMA) for assessing ovarian cancer risk. Materials and methods: ROMA scores were calculated from patients followed surgery to remove a pelvic mass. We compared a false-positive group with a true-negative group of ROMA scores. Results: We analyzed 324 patients using medical records. There were 22 with an epithelial ovarian cancer (EOC), 15 with a borderline ovarian tumor, and 287 with benign disease. Twenty-nine (10.1%) of the patients with benign disease showed high-risk ROMA score (false positive) and 13/37 (35%) patients with EOC, or borderline ovarian tumor showed low ROMA scores (false negatives). The median serum triiodothyronine (T3) level of the false-positive ROMA group in patients with benign disease was lower than in the true-negative ROMA group (p
وصف الملف: electronic resource
العلاقة: http://www.sciencedirect.com/science/article/pii/S1028455920302552Test; https://doaj.org/toc/1028-4559Test
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