المؤلفون: Judith Fraussen, Piet Stinissen, Veerle Somers, Jack van Horssen, Nele Claes, Raymond Hupperts, Bart Van Wijmeersch

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, MUMC+: MA Med Staf Spec Neurologie (9), Klinische Neurowetenschappen

المصدر: Clinical Immunology, 173, 124-132. Academic Press Inc.
Fraussen, J, Claes, N, Van Wijmeersch, B, van Horssen, J, Stinissen, P, Hupperts, R & Somers, V 2016, ' B cells of multiple sclerosis patients induce autoreactive proinflammatory T cell responses ', Clinical Immunology, vol. 173, pp. 124-132 . https://doi.org/10.1016/j.clim.2016.10.001Test

مصطلحات موضوعية: Adult, Male, T-Lymphocytes, T cell, Immunology, Naive B cell, Antigen presentation, T cells, Costimulatory molecules, Multiple sclerosis, Young Adult, 03 medical and health sciences, 0302 clinical medicine, HLA Antigens, Humans, Immunology and Allergy, Medicine, Antigen-presenting cell, B cell, CD86, B-Lymphocytes, B cells, business.industry, multiple sclerosis, antigen presentation, costimulatory molecules, Middle Aged, B-1 cell, medicine.anatomical_structure, B7-1 Antigen, Cytokines, Female, B7-2 Antigen, business, 030217 neurology & neurosurgery, CD80, 030215 immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21fea182daef52e8ff577237906a2882Test
https://research.vumc.nl/en/publications/a983d28d-cd0c-4d27-9ef5-81a7a52d06f8Test

المؤلفون: Wia Baron, Susanne M. A. van der Pol, Jamie L. Lim, Joe M. McCord, Helga E. de Vries, Jack van Horssen

المساهمون: Molecular Neuroscience and Ageing Research (MOLAR), Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation

المصدر: Antioxidants, Vol 5, Iss 3, p 30 (2016)
Lim, J L, van der Pol, S M A, Baron, W, McCord, J M, de Vries, H E & van Horssen, J 2016, ' Protandim protects oligodendrocytes against an oxidative insult ', Antioxidants and Redox Signaling, vol. 5, no. 3, 30 . https://doi.org/10.3390/antiox5030030Test
Antioxidants
Antioxidants; Volume 5; Issue 3; Pages: 30
Antioxidants (Basel, Switzerland), 5(3):30. MDPI AG
Antioxidants and Redox Signaling, 5(3):30. Mary Ann Liebert Inc.

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Physiology, Clinical Biochemistry, Pharmacology, Biology, medicine.disease_cause, multiple sclerosis, Biochemistry, Article, Nrf2, reactive oxygen species, antioxidant enzymes, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Viability assay, Molecular Biology, chemistry.chemical_classification, Reactive oxygen species, lcsh:RM1-950, Cell Biology, Oligodendrocyte, 030104 developmental biology, medicine.anatomical_structure, lcsh:Therapeutics. Pharmacology, chemistry, Tumor necrosis factor alpha, 030217 neurology & neurosurgery, Nicotinamide adenine dinucleotide phosphate, Oxidative stress, Sulforaphane

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162829edc3a7a7239402d1c33b327209Test
http://www.scopus.com/inward/record.url?scp=85010375267&partnerID=8YFLogxKTest

المؤلفون: Adelaide Fernandes, Gisela Santos, Dora Brites, Vera Afonso, Andreia Barateiro, João José Cerqueira, Jack van Horssen

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation, Universidade do Minho

المصدر: Molecular Neurobiology, 53(6), 3976-3991. Humana Press
Barateiro, A, Afonso, V, Santos, G, Cerqueira, J J, Brites, D, van Horssen, J & Fernandes, A 2016, ' S100B as a Potential Biomarker and Therapeutic Target in Multiple Sclerosis ', Molecular Neurobiology, vol. 53, no. 6, pp. 3976-3991 . https://doi.org/10.1007/s12035-015-9336-6Test
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: Male, 0301 basic medicine, Pathology, Inflammasomes, S100B, RAGE (receptor), 0302 clinical medicine, Molecular Targeted Therapy, Aged, 80 and over, Microglia, Middle Aged, White Matter, 3. Good health, Astrogliosis, medicine.anatomical_structure, Neurology, Cytokines, Female, Demyelination, Mitogen-Activated Protein Kinases, Adult, medicine.medical_specialty, Neuroscience (miscellaneous), S100 Calcium Binding Protein beta Subunit, Glial inflammatory response, Multiple sclerosis, Young Adult, 03 medical and health sciences, Cellular and Molecular Neuroscience, Multiple Sclerosis, Relapsing-Remitting, Antigens, Neoplasm, Neutralization Tests, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Humans, Remyelination, Neuroinflammation, Aged, Cell Proliferation, Science & Technology, business.industry, Oligodendrocyte differentiation, Lysophosphatidylcholines, medicine.disease, Antibodies, Neutralizing, Oligodendrocyte, 030104 developmental biology, Gene Expression Regulation, Astrocytes, Case-Control Studies, Chronic Disease, Immunology, Cerebellar organotypic slice cultures, Human samples, business, Biomarkers, 030217 neurology & neurosurgery, Demyelinating Diseases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182cddeb77c9a0a07642db74d7b870f5Test
https://research.vumc.nl/en/publications/dfc73006-a127-4c70-abe0-b3b24a8241a7Test

المؤلفون: Tanja Schichel, Paul van der Valk, Corinne Bernard, Nevena Tzekova, Jack van Horssen, Hans-Peter Hartung, David Kremer, Moritz Förster, Patrick Küry, Hervé Perron

المصدر: Annals of Neurology. 74:721-732

مصطلحات موضوعية: Cellular differentiation, Biology, Neural stem cell, Proinflammatory cytokine, Cell biology, Myelin, medicine.anatomical_structure, Neurology, Precursor cell, Immunology, medicine, TLR4, Neurology (clinical), Remyelination, Receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::535e697faa3cf74cecb2126691dde947Test
https://doi.org/10.1002/ana.23970Test

المؤلفون: Paul van der Valk, Geert J. Schenk, Joost A. R. Drexhage, Sipke Dijkstra, Jack van Horssen, Helga E. de Vries, Albertus J. van het Hof, Susanne M. A. van der Pol, Arie Reijerkerk

المساهمون: Molecular cell biology and Immunology, Anatomy and neurosciences, Pathology, NCA - Neuroinflamation

المصدر: Schenk, G J, Dijkstra, S, van Het Hof, A J, van der Pol, S M A, Drexhage, J A R, van der Valk, P, Reijerkerk, A, van Horssen, J & de Vries, H E 2013, ' Roles for HB-EGF and CD9 in multiple sclerosis ', GLIA, vol. 61, no. 11, pp. 1890-1905 . https://doi.org/10.1002/glia.22565Test
GLIA, 61(11), 1890-1905. John Wiley and Sons Inc.

مصطلحات موضوعية: Adult, Male, Multiple Sclerosis, Inflammation, Biology, Blood–brain barrier, Tetraspanin 29, Lesion, Cellular and Molecular Neuroscience, Epidermal growth factor, Cell Movement, medicine, Humans, Neuroinflammation, Aged, Aged, 80 and over, Multiple sclerosis, Brain, Membrane Proteins, Cell migration, Middle Aged, medicine.disease, Cell biology, Endothelial stem cell, medicine.anatomical_structure, Neurology, Blood-Brain Barrier, Immunology, Intercellular Signaling Peptides and Proteins, Female, medicine.symptom, Heparin-binding EGF-like Growth Factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a766a57199693a2012fe4e7e6c3e15Test
https://doi.org/10.1002/glia.22565Test

المؤلفون: Bert van het Hof, Philip G. Nijland, Maarten E. Witte, Paul van der Valk, Jack van Horssen, Wouter H. Gerritsen, Dirk Geerts, Joost A. R. Drexhage, Arie Reijerkerk, Helga E. de Vries

المساهمون: Molecular cell biology and Immunology, Pathology, NCA - Neuroinflamation, Hematology laboratory

المصدر: Acta Neuropathologica, 125(2), 231-243. Springer Verlag
Acta Neuropathologica, 125(2), 231-43. Springer Verlag
Witte, M E, Nijland, P G, Drexhage, J A R, Gerritsen, W, Geerts, D, van Het Hof, B, Reijerkerk, A, de Vries, H E, van der Valk, P & van Horssen, J 2013, ' Reduced expression of PGC-1 alpha partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex ', Acta Neuropathologica, vol. 125, no. 2, pp. 231-243 . https://doi.org/10.1007/s00401-012-1052-yTest

مصطلحات موضوعية: Adult, Male, Programmed cell death, Multiple Sclerosis, Blotting, Western, Genetic Vectors, Down-Regulation, Cell Count, Tissue Banks, Oxidative phosphorylation, Mitochondrion, Biology, Grey matter, Real-Time Polymerase Chain Reaction, Gyrus Cinguli, Oxidative Phosphorylation, Pathology and Forensic Medicine, Cellular and Molecular Neuroscience, Gyrus, medicine, Humans, Gene silencing, RNA, Small Interfering, Heat-Shock Proteins, Aged, Aged, 80 and over, Cerebral Cortex, Neurons, Pyramidal Cells, Multiple sclerosis, Lentivirus, Neurodegeneration, Middle Aged, medicine.disease, Immunohistochemistry, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Mitochondria, Cell biology, medicine.anatomical_structure, Biochemistry, Female, Neurology (clinical), Reactive Oxygen Species, Oxidation-Reduction, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc49aa78ea271fcc8e86df3ffc50f729Test
https://doi.org/10.1007/s00401-012-1052-yTest

المؤلفون: Esther Witsch, Wiesia Bobkiewicz, Stefan Bittner, Jack van Horssen, Melitta Schachner, Frauke Zipp, Michael K. E. Schäfer, Robin White, Magdalena Paterka, Lutz Menzel, Tanja Kuhlmann

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation

المصدر: Menzel, L, Paterka, M, Bittner, S, White, R, Bobkiewicz, W, van Horssen, J, Schachner, M, Witsch, E, Kuhlmann, T, Zipp, F & Schaefer, M K E 2016, ' Down-regulation of neuronal L1 cell adhesion molecule expression alleviates inflammatory neuronal injury ', Acta Neuropathologica, vol. 132, no. 5, pp. 703-720 . https://doi.org/10.1007/s00401-016-1607-4Test
Acta Neuropathologica, 132(5), 703-720. Springer Verlag

مصطلحات موضوعية: 0301 basic medicine, Male, Encephalomyelitis, Autoimmune, Experimental, L1, T-Lymphocytes, Cell, Down-Regulation, Mice, Transgenic, Nerve Tissue Proteins, Neural Cell Adhesion Molecule L1, Biology, Pathology and Forensic Medicine, Myelin oligodendrocyte glycoprotein, 03 medical and health sciences, Cellular and Molecular Neuroscience, Mice, 0302 clinical medicine, Immune system, medicine, Animals, Humans, Myelin Proteolipid Protein, Neuroinflammation, Aged, Neurons, Multiple sclerosis, HEK 293 cells, Middle Aged, medicine.disease, Synapsins, Axons, Coculture Techniques, Peptide Fragments, Myelin proteolipid protein, Cell biology, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, HEK293 Cells, nervous system, Immunology, biology.protein, Female, Myelin-Oligodendrocyte Glycoprotein, Neurology (clinical), 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96c209b0b1ade766ad950c8a2dab531Test
https://pubmed.ncbi.nlm.nih.gov/27544757Test

المؤلفون: Jack van Horssen, Maria João Gama, Luciano Saso, Andreia Neves Carvalho, Omidreza Firuzi

المساهمون: Molecular cell biology and Immunology, Amsterdam Neuroscience - Neuroinfection & -inflammation

المصدر: Current Drug Targets, 18(6), 705-718. Bentham Science Publishers B.V.
Carvalho, A N, Firuzi, O, Gama, M J, van Horssen, J & Saso, L 2017, ' Oxidative stress and antioxidants in neurological diseases : Is there still hope? ', Current Drug Targets, vol. 18, no. 6, pp. 705-718 . https://doi.org/10.2174/1389450117666160401120514Test

مصطلحات موضوعية: 0301 basic medicine, huntington's disease, Parkinson's disease, NF-E2-Related Factor 2, Clinical Biochemistry, Central nervous system, Disease, Pharmacology, Biology, multiple sclerosis, Bioinformatics, Blood–brain barrier, medicine.disease_cause, Antioxidants, 03 medical and health sciences, 0302 clinical medicine, Huntington's disease, Drug Discovery, medicine, Humans, Clinical Trials as Topic, Mechanism (biology), Multiple sclerosis, biomarkers, Neurodegenerative Diseases, medicine.disease, Oxidative Stress, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, Blood-Brain Barrier, parkinson's disease, alzheimer's disease, Molecular Medicine, antioxidants, neurodegenerative diseases, oxidative stress, Reactive Oxygen Species, 030217 neurology & neurosurgery, Oxidative stress, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc01331a690d160c961458d5142d55fTest
https://pubmed.ncbi.nlm.nih.gov/27033198Test

المؤلفون: Robin White, Paul van der Valk, Maarten E. Witte, Jack van Horssen, Christina Moos, Heiko J. Luhmann, Nina M. Bauer, Benjamin Altenhein

المساهمون: Molecular cell biology and Immunology, Pathology, NCA - Multiple Sclerosis and Other Neuroinflammatory Diseases

المصدر: EMBO Reports, 13(9), 827-834. Wiley-Blackwell
Bauer, N M, Moos, C, van Horssen, J, Witte, M E, van der Valk, P, Altenhein, B, Luhmann, H J & White, R 2012, ' Myelin Basic Protein synthesis is regulated by small non-coding RNA 715 ', EMBO Reports, vol. 13, no. 9, pp. 827-834 . https://doi.org/10.1038/embor.2012.97Test

مصطلحات موضوعية: Multiple Sclerosis, Cytoplasmic Granules, Biochemistry, Cell Line, Mice, Genetics, medicine, Protein biosynthesis, Animals, Humans, MRNA transport, RNA, Messenger, Molecular Biology, Myelin Sheath, Messenger RNA, biology, Scientific Reports, Oligodendrocyte differentiation, Brain, RNA, Myelin Basic Protein, Non-coding RNA, Molecular biology, Oligodendrocyte, Rats, Myelin basic protein, Oligodendroglia, medicine.anatomical_structure, Gene Expression Regulation, Protein Biosynthesis, biology.protein, RNA, Small Untranslated

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331bef722205ecaaafc3ff795645a140Test
https://doi.org/10.1038/embor.2012.97Test

المؤلفون: Micha M.M. Wilhelmus, Philip G. Nijland, Helga E. de Vries, Jack van Horssen, Benjamin Drukarch

المساهمون: Anatomy and neurosciences, Pathology, Molecular cell biology and Immunology, NCA - Neurodegeneration

المصدر: Wilhelmus, M M M, Nijland, P G, Drukarch, B, de Vries, H E & van Horssen, J 2012, ' Involvement and interplay of Parkin, PINK1, and DJ1 in neurodegenerative and neuroinflammatory disorders ', Free Radical Biology and Medicine, vol. 53, no. 4, pp. 983-992 . https://doi.org/10.1016/j.freeradbiomed.2012.05.040Test
Free Radical Biology and Medicine, 53(4), 983-992. Elsevier Inc.

مصطلحات موضوعية: Multiple Sclerosis, Ubiquitin-Protein Ligases, Protein Deglycase DJ-1, PINK1, medicine.disease_cause, Biochemistry, Neuroprotection, Parkin, Physiology (medical), medicine, Animals, Humans, Genetics, Inflammation, Oncogene Proteins, biology, Neurodegeneration, Intracellular Signaling Peptides and Proteins, Neurodegenerative Diseases, medicine.disease, nervous system diseases, Ubiquitin ligase, Oxidative Stress, Proteasome, biology.protein, Neuroscience, Protein Kinases, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b439a7d90c7bdbdbcb08100e1031abTest
https://doi.org/10.1016/j.freeradbiomed.2012.05.040Test