المؤلفون: Schmitt, Andreas, Beran, Magdalena, Geraets, Anouk, Iversen, Marjolein M., Nefs, Giesje, Nouwen, Arie, Pouwer, Frans, Huber, J. rg W., Schram, Miranda T.

المصدر: Schmitt , A , Beran , M , Geraets , A , Iversen , M M , Nefs , G , Nouwen , A , Pouwer , F , Huber , J R W & Schram , M T 2024 , ' Associations between HbA1c Reduction and Change in Depressive Symptoms following Glucose-lowering Treatment in Adults : A Systematic Review of Intervention Studies ' , Current Diabetes Reviews , vol. 20 , no. 3 , e020623217607 , pp. 66-83 . https://doi.org/10.2174/1573399820666230602124223Test

الوصف: Introduction: Hyperglycemia constitutes a likely pathway linking diabetes and depressive symptoms; lowering glycemic levels may help reduce diabetes-comorbid depressive symptoms. Since randomized controlled trials can help understand temporal associations, we systematically reviewed the evidence regarding the potential association of hemoglobin HbA1c lowering interventions with depressive symptoms. Methods: PubMed, PsycINFO, CINAHL, and EMBASE databases were searched for randomized controlled trials evaluating HbA1c-lowering interventions and including assessment of depressive symptoms published between 01/2000-09/2020. Study quality was evaluated using the Cochrane Risk of Bias tool. PROSPERO reg-istration: CRD42020215541. Results: We retrieved 1,642 studies of which twelve met our inclusion criteria. Nine studies had high and three unclear risks of bias. Baseline depressive symptom scores suggest elevated depressive symptoms in five stud-ies. Baseline HbA1c was <8.0% (<64 mmol/mol) in two, 8.0-9.0% (64-75 mmol/mol) in eight, and ≥10.0% (≥86 mmol/mol) in two studies. Five studies found greater HbA1c reduction in the treatment group; three of these found greater depressive symptom reduction in the treatment group. Of four studies analyzing whether the change in HbA1c was associated with the change in depressive symptoms, none found a significant association. The main limitation of these studies was relatively low levels of depressive symptoms at baseline, limiting the ability to show a lowering in depressive symptoms after HbA1c reduction. Conclusions: We found insufficient available data to estimate the association between HbA1c reduction and depressive symptom change following glucose-lowering treatment. Our findings point to an important gap in the diabetes treatment literature. Future clinical trials testing interventions to improve glycemic outcomes might consider measuring depressive symptoms as an outcome to enable analyses of this association.

العلاقة: https://research.vumc.nl/en/publications/93da7da9-9164-462f-82a1-3a950fa4c02fTest

الإتاحة: https://doi.org/10.2174/1573399820666230602124223Test
https://research.vumc.nl/en/publications/93da7da9-9164-462f-82a1-3a950fa4c02fTest
http://www.scopus.com/inward/record.url?scp=85184674867&partnerID=8YFLogxKTest

المؤلفون: Hernar, Ingvild, Cooper, John G., Nilsen, Roy M., Skinner, Timothy C., Strandberg, Ragnhild B., Iversen, Marjolein M., Graue, Marit, Ernes, Tony, Løvaas, Karianne F., Madsen, Tone V., Lie, Silje S., Richards, David A., Ueland, Grethe, Haugstvedt, Anne

المصدر: Hernar , I , Cooper , J G , Nilsen , R M , Skinner , T C , Strandberg , R B , Iversen , M M , Graue , M , Ernes , T , Løvaas , K F , Madsen , T V , Lie , S S , Richards , D A , Ueland , G & Haugstvedt , A 2024 , ' Diabetes Distress and Associations With Demographic and Clinical Variables : A Nationwide Population-Based Registry Study of 10,186 Adults With Type 1 Diabetes in Norway ' , Diabetes Care , vol. 47 , ....

الوصف: OBJECTIVE To estimate diabetes distress prevalence and associations with demographic and clinical variables among adults with type 1 diabetes in Norway. RESEARCH DESIGN AND METHODS In this nationwide population-based registry study, the 20-item Problem Areas in Diabetes (PAID-20) questionnaire was sent to 16,255 adults with type 1 diabetes. Linear regression models examined associations of demographic and clinical variables with distress. RESULTS In total, 10,186 individuals (62.7%) completed the PAID-20, with a mean score of 25.4 (SD 18.4) and 21.7% reporting high distress. Respondents endorsed worrying about the future and complications as the most problematic item (23.0%). Female sex, younger age, non-European origin, primary education only, unemployment, smoking, continuous glucose monitoring use, more symptomatic hypoglycemia, reduced foot sensitivity, treated retinopathy, and higher HbA 1c were associated with higher distress. CONCLUSIONS Diabetes distress is common among adults with type 1 diabetes and associated with clinically relevant factors, underlining that regular care should include efforts to identify and address distress.

الإتاحة: https://doi.org/10.2337/dc23-1001Test
https://curis.ku.dk/portal/da/publications/diabetes-distress-and-associations-with-demographic-and-clinical-variablesTest(d9614883-2324-41cf-8f45-a00fbc337ebd).html
http://www.scopus.com/inward/record.url?scp=85180436213&partnerID=8YFLogxKTest

المؤلفون: Riise, Hilde K. R., Igland, Jannicke, Graue, Marit, Haugstvedt, Anne, Østbye, Truls, Søfteland, Eirik, Hermann, Monica, Carlsson, Sofia, Åsvold, Bjørn Olav, Iversen, Marjolein M.

المصدر: Frontiers in Endocrinology ; volume 15 ; ISSN 1664-2392

الوصف: Background and aims Diabetes-related foot ulcers (DFU) are a persistent healthcare challenge, impacting both patients and healthcare systems, with adverse effects on quality of life and productivity. Our primary aim was to examine the trends in lifetime prevalence of DFU, as well as other micro- and macrovascular complications in the Trøndelag Health Study (HUNT) in Norway. Methods This study consists of individuals ≥20 years with diabetes participating in the population-based cross-sectional HUNT surveys (1995-2019). Prevalence ratios, comparing the lifetime prevalence of DFU and other relevant micro- and macrovascular complications between the HUNT surveys, were calculated using Poisson regression. Results The lifetime prevalence (95% confidence interval (CI)) of a DFU requiring three or more weeks to heal was 11.0% (9.5-12.7) in HUNT2, 7.5% (6.3-8.8) in HUNT3 and 5.3% (4.4-6.3) in HUNT4. The decrease in DFU prevalence from 1995 to 2019 was observed in both men and women, for all age groups, and for both type 1 and type 2 diabetes. The highest lifetime prevalence of DFU was found among those with type 1 diabetes. The decrease in HbA1c from HUNT2 to HUNT4 did not differ between those with and without a DFU. The prevalence of chronic kidney disease (eGFR <60 mL/min/1.73 m 2 (eGFR categories G3-G5)) increased in both individuals with and without a DFU. Conclusion Results from the HUNT surveys show a substantial decline in the lifetime prevalence of DFU from 1995 to 2019.

الإتاحة: https://doi.org/10.3389/fendo.2024.1354385Test

المؤلفون: Strandberg, Ragnhild B., Nilsen, Roy M., Pouwer, Frans, Igland, Jannicke, Forster, Rachel B., Jenum, Anne Karen, Buhl, Esben S., Iversen, Marjolein M.

المصدر: Strandberg , R B , Nilsen , R M , Pouwer , F , Igland , J , Forster , R B , Jenum , A K , Buhl , E S & Iversen , M M 2023 , ' Lower education and immigrant background are associated with lower participation in a diabetes education program – Insights from adult patients in the Outcomes & Multi-morbidity In Type 2 diabetes cohort (OMIT) ' , Patient Education and Counseling , vol. 107 , 107577 . https://doi.org/10.1016/j.pec.2022.107577Test

الوصف: Objectives: Diabetes educational programmes should be offered to patients with type 2 diabetes mellitus (T2DM). We assessed the proportion of diabetes educational program participation among adults with T2DM, and its associations with place of residence in Norway, education, and immigrant background. Methods: We identified 28,128 diagnosed with T2DM (2008–2019) in the Outcomes & Multi-morbidity In Type 2 diabetes cohort. To examine associations between sociodemographic factors and participation in diabetes start courses (yes/no), we computed adjusted risk ratios (95% CI) using log-binomial regression. Results: Overall, 18% participated on the diabetes start course, but partaking differed by Norwegian counties (range:12–34%). Individuals with an immigrant background were 29% less likely to participate (RR 0.71, CI 0.65–0.79). Similarly, those with a lower educational level were 23% less likely to participate (RR 0.77, CI 0.72–0.83) than those with the highest education. The association between education and start course participation was not significant in the subgroup of immigrant individuals (RR 0.88 CI 0.70–1.12). Conclusions: We found that diabetes start course participation was overall low, especially in individuals with low education and immigrant background. Practice implications: More efforts are needed to promote diabetes start courses in patients with T2DM.

العلاقة: https://research.vumc.nl/en/publications/9a404afa-16aa-462a-a3ca-92475de64c4aTest

الإتاحة: https://doi.org/10.1016/j.pec.2022.107577Test
https://research.vumc.nl/en/publications/9a404afa-16aa-462a-a3ca-92475de64c4aTest
http://www.scopus.com/inward/record.url?scp=85144596046&partnerID=8YFLogxKTest

المؤلفون: Nguyen, Michael Quan, Broström, Anders, Iversen, Marjolein M., Harboe, Knut, Paulsen, Aksel

المصدر: 18 ; Journal of Orthopaedic Surgery and Research ; 941 (2023)

مصطلحات موضوعية: ankelbrudd, kirurgi, VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Generell kirurgi: 780

الوصف: Background Roughly 10% of fractures in adults are ankle fractures. These injuries are found in both sexes and present with different fracture characteristics. The treatment varies with the patients’ biology and fracture type, and the goals are to restore stability, prevent pain and maintain ankle function. Clinicians generally use outcomes like assessment of radiography, pain level, or function. The use of patient-reported outcome measures is increasing, and the Manchester–Oxford Foot Questionnaire (MOXFQ) has been shown to have good measurement properties when validated in patients with foot and ankle disorders. However, the instrument has not been validated for ankle fracture patients. This study aims to assess the content validity of the items in MOXFQ in surgically treated ankle fracture patients. Methods A qualitative deductive design was used to investigate patients’ response process of the MOXFQ. Individual interviews were conducted using cognitive interviewing based on the theoretical framework of the 4-step model by Tourangeau. Adult patients that were surgically treated for an ankle fracture between four weeks and 18 months were purposively sampled, and interviews followed a semi-structured interview guide. The predetermined categories were comprehension, retrieval, judgement, and response. Results Seventeen respondents (65% females) were interviewed. Respondents’ age ranged from 27 to 76 years. Some of the respondents in the early recovery phase were limited by post-operative restrictions and did not find the items in the walking/standing domain relevant. Respondents that were allowed weight-bearing as tolerated (WBAT) were able to recall relevant information for most items. Respondents with time since surgery more than 12 months had less pain and remembered fewer relevant episodes in the recall period. Items in the social interaction domain contained ambiguous questions and were generally considered less important by respondents. The summary index score lacked important concepts in measuring overall ...

وصف الملف: application/pdf

العلاقة: Nguyen, M., Broström, A., Iversen, M.M., Harboe, K. & Paulsen, A. (2023) Assessing the content validity of the Manchester–Oxford Foot Questionnaire in surgically treated ankle fracture patients: a qualitative study. Journal of Orthopaedic Surgery and Research, 18, 941 (2023); urn:issn:1749-799X; https://hdl.handle.net/11250/3109144Test; https://doi.org/10.1186/s13018-023-04418-9Test; cristin:2211066

الإتاحة: https://doi.org/10.1186/s13018-023-04418-9Test
https://hdl.handle.net/11250/3109144Test

المؤلفون: Madsen, Tone Vonheim, Cooper, John Graham, Carlsen, Siri, Loevaas, Karianne, Rekdal, Magne, Igland, Jannicke, Sandberg, Sverre, Ueland, Grethe Åstrøm, Iversen, Marjolein M., Sølvik, Una Ørvim

المصدر: e002099 ; BMJ Open Quality ; 12 ; 2

الوصف: Background Patients with type 1 diabetes mellitus (T1DM) and poor glycaemic control are at high risk of developing microvascular and macrovascular complications. The aim of this study was to determine if a quality improvement collaborative (QIC) initiated by the Norwegian Diabetes Register for adults (NDR-A) could reduce the proportion of patients with T1DM with poor glycaemic control (defined as glycated haemoglobin (HbA1c)≥75 mmol/mol) and reduce mean HbA1c at participating clinics compared with 14 control clinics. Method Multicentre study with controlled before and after design. Representatives of 13 diabetes outpatient clinics (n=5145 patients with T1DM) in the intervention group attended four project meetings during an 18-month QIC. They were required to identify areas requiring improvement at their clinic and make action plans. Continuous feedback on HbA1c outcomes was provided by NDR-A during the project. In total 4084 patients with type 1 diabetes attended the control clinics. Results Between 2016 and 2019, the overall proportion of patients with T1DM and HbA1c≥75 mmol/mol in the intervention group were reduced from 19.3% to 14.1% (p<0.001). Corresponding proportions in the control group were reduced from 17.3% (2016) to 14.4% (2019) (p<0.001). Between 2016 and 2019, overall mean HbA1c decreased by 2.8 mmol/mol (p<0.001) at intervention clinics compared with 2.3 mmol/mol (p<0.001) at control clinics. After adjusting for the baseline differences in glycaemic control, there were no significant differences in the overall improvement in glycaemic control between intervention and control clinics. Conclusions The registry linked QIC did not result in a significantly greater improvement in glycaemic control at intervention clinics compared with control clinics. However, there has been a sustained improvement in glycaemic control and importantly a significant reduction in the proportion of patients with poor glycaemic control at both intervention and control clinics during and after the QIC time ...

وصف الملف: application/pdf

العلاقة: urn:issn:2399-6641; https://hdl.handle.net/11250/3086038Test; https://doi.org/10.1136/bmjoq-2022-002099Test; cristin:2161732; BMJ Open Quality. 2023, 12 (2), e002099 .

الإتاحة: https://doi.org/10.1136/bmjoq-2022-002099Test
https://hdl.handle.net/11250/3086038Test

المؤلفون: Stalheim, Astrid Melteig, Iversen, Marjolein M., Jenum, Anne Karen, Sletner, Line, Stafne, Signe Nilssen, Qvigstad, Elisabeth, Sagedal, Linda Reme, Nilsen, Roy Miodini, Aasheim, Vigdis, Strandberg, Ragnhild Bjarkøy

المصدر: 2044-6055.

الوصف: Objectives Previous research on seasonal variation in the incidence of gestational diabetes mellitus (GDM) has shown inconclusive results. Furthermore, little is known about whether a seasonal variation in GDM might be associated with the maternal country of birth. We examined whether there was seasonal variation in GDM incidence by the maternal country background. Design National population-based registry study. Setting and participants We used national population-based data from the Medical Birth Registry of Norway (MBRN), n=1 443 857 (1990–2016) and data from four merged community-based studies (4GDM) with universal screening for GDM, n=2 978 (2002–2013). Outcome measures The association between season of pregnancy onset with incidence of GDM was examined separately in both datasets using logistic regression analyses, stratified by the mother’s country background using two broad geographical categories (MBRN: Norwegian and immigrant; 4GDM: European and African/Asian ethnicity). Winter season was used as reference category. Results The incidence of GDM in MBRN was highest when the pregnancy started during the winter (Norwegian-born: 1.21%; immigrants: 3.32%) and lowest when pregnancy started during the summer for both Norwegian and immigrant women (Norwegian-born: 1.03% (OR 0.85, 95% CI 0.81 to 0.98); immigrants: 2.99% (OR 0.90, 95% CI 0.84 to 0.96)). The 4GDM data showed that women with European ancestry had the highest incidence of GDM when pregnancy started during autumn (10.7%, OR 1.01, 95% CI 0.69 to 1.46) and winter (10.6%), while ethnic African and Asian women had the highest incidence when pregnancy onset was during the summer (15.3%, OR 1.17, 95% CI 0.54 to 2.53). Conclusions Based on national population-based data, this study suggests that GDM incidence varies by season in both Norwegian-born and immigrant women. The 4GDM dataset did not show a clear seasonal variation in GDM incidence, possibly due to the relatively small sample. Causes for the seasonal variation in GDM should be explored further.

العلاقة: Stalheim, Astrid Melteig Iversen, Marjolein M. Jenum, Anne Karen Sletner, Line Stafne, Signe Nilssen Qvigstad, Elisabeth Sagedal, Linda Reme Nilsen, Roy Miodini Aasheim, Vigdis Strandberg, Ragnhild Bjarkøy . Seasonal variation in gestational diabetes mellitus among women in Norway: a national population-based study. BMJ Open. 2023, 13(3), 1-8; http://hdl.handle.net/10852/103390Test; 2138829; info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=BMJ Open&rft.volume=13&rft.spage=1&rft.date=2023; BMJ Open; 13; https://doi.org/10.1136/bmjopen-2022-063725Test

الإتاحة: https://doi.org/10.1136/bmjopen-2022-063725Test
http://hdl.handle.net/10852/103390Test

المؤلفون: Lecuona, Oscar, Lin, Chung-Ying, Rozgonjuk, Dmitri, Norekvål, Tone M., Iversen, Marjolein M., Mamun, Mohammed A., Griffiths, Mark D., Lin, Ting-I, Pakpour, Amir H.

المصدر: International Journal of Environmental Research and Public Health. 19(11)

مصطلحات موضوعية: Bangladesh, COVID-19, Iran, Norway, fear, network analysis

الوصف: The rapid spread of the coronavirus disease 2019 (COVID-19) has led to high levels of fear worldwide. Given that fear is an important factor in causing psychological distress and facilitating preventive behaviors, assessing the fear of COVID-19 is important. The seven-item Fear of COVID-19 Scale (FCV-19S) is a widely used psychometric instrument to assess this fear. However, the factor structure of the FCV-19S remains unclear according to the current evidence. Therefore, the present study used a network analysis to provide further empirical evidence for the factor structure of FCV-19S. A total of 24,429 participants from Iran (n = 10,843), Bangladesh (n = 9906), and Norway (n = 3680) completed the FCV-19S in their local language. A network analysis (via regularized partial correlation networks) was applied to investigate the seven FCV-19S items. Moreover, relationships between the FCV-19S items were compared across gender (males vs. females), age groups (18-30 years, 31-50 years, and >50 years), and countries (Iran, Bangladesh, and Norway). A two-factor structure pattern was observed (three items concerning physical factors, including clammy hands, insomnia, and heart palpitations; four items concerning psychosocial factors, including being afraid, uncomfortable, afraid of dying, and anxious about COVID-19 news). Moreover, this pattern was found to be the same among men and women, across age groups and countries. The network analysis used in the present study verified the two-factor structure for the FCV-19S. Future studies may consider using the two-factor structure of FCV-19S to assess the fear of COVID-19 during the COVID-19 era.

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-57659Test
https://doi.org/10.3390/ijerph19116824Test

المؤلفون: T Schram, Miranda, Schmitt, Andreas, Beran, Magdalena, Geraets, Anouk, Iversen, Marjolein M, Nefs, Giesje, Nouwen, Arie, Pouwer, Frans, Huber, Jörg W

مصطلحات موضوعية: psy, socio

الوصف: Introduction: Hyperglycemia constitutes a likely pathway linking diabetes and depressive symptoms; lowering glycemic levels may help reduce diabetes-comorbid depressive symptoms. Since randomized controlled trials can help understand temporal associations, we systematically reviewed the evidence regarding the potential association of hemoglobin A1C (HbA1c)-lowering interventions with depressive symptoms. Methods: PubMed, PsycINFO, CINAHL, and EMBASE databases were searched for randomized controlled trials evaluating A1C-lowering interventions and including assessment of depressive symptoms published between 01/2000–09/2020. Study quality was evaluated using the Cochrane Risk of Bias tool. PROSPERO registration: CRD42020215541. Results: We retrieved 1,642 studies of which twelve met our inclusion criteria. Nine studies had high and three unclear risks of bias. Baseline depressive symptom scores suggest elevated depressive symptoms in five studies. Baseline HbA1c was <8.0% (<64mmol/mol) in two, 8.0–9.0% (64–75mmol/mol) in eight, and ≥10.0% (≥86mmol/mol) in two studies. Of five studies that found greater HbA1c reduction in the treatment group, three also found greater depressive symptom reduction in the treatment group. Of four studies analyzing whether the change in HbA1c was associated with the change in depressive symptoms, none found a significant association. The main limitation of these studies was relatively low levels of depressive symptoms at baseline, limiting the ability to show a lowering in depressive symptoms after HbA1c reduction. Conclusions: We found insufficient available data to estimate the association between HbA1c reduction and depressive symptom change following glucose-lowering treatment. Our findings point to an important gap in the diabetes treatment literature. Future clinical trials testing interventions to improve glycemic outcomes might consider measuring depressive symptoms as an outcome to enable analyses of this association.

العلاقة: https://oro.open.ac.uk/89679Test/

الإتاحة: https://oro.open.ac.uk/89679Test/

المؤلفون: Igland, Jannicke, Forster, Rachel Bedenis, Jenum, Anne Karen, Strandberg, Ragnhild Bjarkøy, Berg, Tore Julsrud, Røssberg, Jan Ivar, Iversen, Marjolein M., Buhl, Esben Selmer

المصدر: Igland, Jannicke Forster, Rachel Bedenis Jenum, Anne Karen Strandberg, Ragnhild Bjarkøy Berg, Tore Julsrud Røssberg, Jan Ivar Iversen, Marjolein M. Buhl, Esben Selmer . How valid is a prescription-based multimorbidity index (Rx-risk) in predicting mortality in the Outcomes and Multimorbidity In Type 2 diabetes (OMIT) study? A nation-wide registry-based cohort study from Norway. BMJ Open. 2024, 14(3)
BMJ Open

الإتاحة: http://hdl.handle.net/10852/111315Test