المؤلفون: Euskirchen, Philipp, Radke, Josefine, Dieterich, Christoph, Miletic, Hrvoje, Mørk, Sverre, Koch, Arend, Endres, Matthias, Harms, Christoph, Schmidt, Marc Sören, Schulze Heuling, Eva, Kadikowski, Eric, Maricos, Meron, Knab, Felix, Grittner, Ulrike, Zerbe, Norman, Czabanka, Marcus

المصدر: PLOS ONE 12(9), e0185376 (2017). doi:10.1371/journal.pone.0185376

مصطلحات موضوعية: info:eu-repo/classification/ddc/610, Brain Neoplasms: genetics, Brain Neoplasms: metabolism, Brain Neoplasms: pathology, Cell Line, Tumor, ErbB Receptors: genetics, ErbB Receptors: metabolism, Glioblastoma: genetics, Glioblastoma: metabolism, Glioblastoma: pathology, Glioma: genetics, Glioma: metabolism, Glioma: pathology, Humans, Immunohistochemistry, In Situ Hybridization, Fluorescence, Isocitrate Dehydrogenase: genetics, Isocitrate Dehydrogenase: metabolism, Mutation, RNA, Messenger: genetics, Messenger: metabolism, Neoplasm: genetics, Neoplasm: metabolism, Transcriptome, Tumor Microenvironment: genetics, Tumor Microenvironment: immunology, Zinc Finger E-box-Binding Homeobox 1: genetics

جغرافية الموضوع: DE

العلاقة: info:eu-repo/semantics/altIdentifier/issn/1932-6203; info:eu-repo/semantics/altIdentifier/pmid/pmid:28945795; https://pub.dzne.de/record/139525Test; https://pub.dzne.de/search?p=id:%22DZNE-2020-05847%22Test

الإتاحة: https://doi.org/10.1371/journal.pone.0185376Test
https://pub.dzne.de/record/139525Test
https://pub.dzne.de/search?p=id:%22DZNE-2020-05847%22Test

المؤلفون: Draaisma, Kaspar, Tesileanu, C Mircea S, de Heer, Iris, Klein, Martin, Smits, Marion, Reijneveld, Jaap C, Clement, Paul M, De Vos, Filip, Wick, Antje, Mulholland, Paul, Taphoorn, Martin, Weller, Michael, Chinot, Olivier L, Kros, Johan M, Verschuere, Tina, Coens, Corneel, Golfinopoulos, Vassilis, Gorlia, Thierry, Idbaih, Ahmed, Robe, Pierre A, van den Bent, Martin J, French, Pim J

المساهمون: MS Medische Oncologie, Cancer, Neurochirurgie, Brain

مصطلحات موضوعية: Brain Neoplasms/pathology, DNA Methylation, DNA Modification Methylases/genetics, DNA Repair Enzymes/genetics, Glioma/pathology, Homozygote, Humans, Isocitrate Dehydrogenase/genetics, Magnetic Resonance Imaging, Mutation, Neoplasm Recurrence, Local/genetics, Prognosis, Sequence Deletion, Oncology, Cancer Research, Randomized Controlled Trial, Clinical Trial, Phase II, Journal Article

وصف الملف: application/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/445962Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/445962Test

المؤلفون: Jean-Yves Blay, Angelica Fasolo, Palanichamy Ilankumaran, Tae Min Kim, Daniel C Cho, Jeffrey Yachnin, Filip de Vos, Martin J. van den Bent, Eduard Gasal, Albert Lai, Antje Wick, Mario Campone, Damien Pouessel, Myra E. van Linde, Alexander Stein, Jacques De Greve, Warren P. Mason, Jose A. Lopez-Martin, Anas Gazzah, Nikolas von Bubnoff, Vivek Subbiah, Gerald W. Prager, Ralf-Dieter Hofheinz, Patrick Y. Wen, Aislyn Boran, Paul Burgess

المساهمون: Neurology, Internal medicine, CCA - Cancer Treatment and quality of life, Medical Genetics, Clinical sciences, Laboratory for Medical and Molecular Oncology

المصدر: The Lancet Oncology, 23(1), 53-64. Lancet Publishing Group
Wen, P Y, Stein, A, van den Bent, M, de Greve, J, Wick, A, de Vos, F Y F L, von Bubnoff, N, van Linde, M E, Lai, A, Prager, G W, Campone, M, Fasolo, A, Lopez-Martin, J A, Kim, T M, Mason, W P, Hofheinz, R-D, Blay, J-Y, Cho, D C, Gazzah, A, Pouessel, D, Yachnin, J, Boran, A, Burgess, P, Ilankumaran, P, Gasal, E & Subbiah, V 2022, ' Dabrafenib plus trametinib in patients with BRAFV600E-mutant low-grade and high-grade glioma (ROAR) : a multicentre, open-label, single-arm, phase 2, basket trial ', The Lancet Oncology, vol. 23, no. 1, pp. 53-64 . https://doi.org/10.1016/S1470-2045Test(21)00578-7

مصطلحات موضوعية: Adult, Male, Oncology, medicine.medical_specialty, Adolescent, Neuroscience(all), Population, Oximes/administration & dosage, Brain Neoplasms/drug therapy, Isocitrate Dehydrogenase/genetics, Neutropenia, SDG 3 - Good Health and Well-being, Internal medicine, Glioma, Proto-Oncogene Proteins B-raf/genetics, Internal Medicine, medicine, Clinical endpoint, Humans, education, Aged, Trametinib, education.field_of_study, Pyridones/administration & dosage, business.industry, Antineoplastic Combined Chemotherapy Protocols/adverse effects, neurology, Dabrafenib, Middle Aged, Interim analysis, medicine.disease, Glioma/drug therapy, Cohort, young adult, Female, Pyrimidinones/administration & dosage, mutation, business, Imidazoles/administration & dosage, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fad158cf6a3776974f72e32f6f4611eTest
https://pure.eur.nl/en/publications/6534e7d9-0966-4ffb-83ef-1054a6161e37Test

المساهمون: Sun Min Lim, Junjeong Choi, Jong Hee Chang, Jinyoung Sohn, Kristine Jacobson, Frank Policht, John Schulz, Byoung Chul Cho, Se Hoon Kim, Cho, Byoung Chul, Kim, Se Hoon, Lim, Sun Min, Chang, Jong Hee

المصدر: T201503518.pdf

مصطلحات موضوعية: Adult, Aged, 80 and over, Biomarkers/metabolism, DNA Methylation, DNA Modification Methylases/genetics, DNA Repair Enzymes/genetics, Female, Gene Rearrangement, Glioblastoma/diagnosis, Glioblastoma/genetics, Humans, Immunohistochemistry, In Situ Hybridization, Fluorescence, Isocitrate Dehydrogenase/genetics, Male, Middle Aged, Multivariate Analysis, Pilot Projects, Prognosis, Promoter Regions, Genetic, Protein-Tyrosine Kinases/genetics, Proto-Oncogene Proteins/genetics, Tumor Suppressor Proteins/genetics

وصف الملف: e0137678

العلاقة: PLOS ONE; J02540; OAK-2015-01981; https://ir.ymlib.yonsei.ac.kr/handle/22282913/141141Test; T201503518; PLOS ONE, Vol.10(9) : e0137678, 2015

الإتاحة: https://doi.org/10.1371/journal.pone.0137678Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/141141Test

المؤلفون: Itsumi, M, Inoue, S, Elia, A J, Murakami, K, Sasaki, M, Lind, E F, BRENNER, Dirk, Harris, I S, Chio, I I C, Afzal, S, Cairns, R A, Cescon, D W, Elford, A R, Ye, J, Lang, P A, Li, W Y, Wakeham, A, Duncan, G S, Haight, J, You-Ten, A, Snow, B, Yamamoto, K, Ohashi, P S, Mak, T W

المصدر: Cell Death and Differentiation, 22 (11), 1837 - 1845 (2015-11)

مصطلحات موضوعية: Endotoxins, NADP, Isocitrate Dehydrogenase, Animals, Cells, Cultured, Endotoxins/pharmacology, Flow Cytometry, Hepatocytes/drug effects, Hepatocytes/enzymology, Isocitrate Dehydrogenase/genetics, Isocitrate Dehydrogenase/metabolism, Mice, Knockout, NADP/metabolism, Oxidative Stress/drug effects, Oxidative Stress/genetics, Reverse Transcriptase Polymerase Chain Reaction, Hepatocytes, Oxidative Stress, Molecular Biology, Cell Biology, Human health sciences, Immunology & infectious disease, Sciences de la santé humaine, Immunologie & maladie infectieuse

العلاقة: http://www.nature.com/articles/cdd201538.pdfTest; urn:issn:1350-9047; urn:issn:1476-5403; https://orbilu.uni.lu/handle/10993/57971Test; info:hdl:10993/57971; https://orbilu.uni.lu/bitstream/10993/57971/1/Itsumi%20M%20et%20al_Cell%20Death%20and%20Differentiation%202015.pdfTest; scopus-id:2-s2.0-84943200604; info:pmid:25882048; wos:000362438500011

الإتاحة: https://doi.org/10.1038/cdd.2015.38Test
https://orbilu.uni.lu/handle/10993/57971Test
https://orbilu.uni.lu/bitstream/10993/57971/1/Itsumi%20M%20et%20al_Cell%20Death%20and%20Differentiation%202015.pdfTest

المؤلفون: Wirsching, H.G., Roelcke, U., Weller, J., Hundsberger, T., Hottinger, A.F., von Moos, R., Caparrotti, F., Conen, K., Remonda, L., Roth, P., Ochsenbein, A., Tabatabai, G., Weller, M.

المصدر: Clinical cancer research, vol. 27, no. 1, pp. 179-188

مصطلحات موضوعية: Aged, 80 and over, Bevacizumab/therapeutic use, Brain/diagnostic imaging, Brain/pathology, Brain Neoplasms/diagnosis, Brain Neoplasms/genetics, Brain Neoplasms/mortality, Brain Neoplasms/therapy, Chemoradiotherapy/methods, Chemoradiotherapy/statistics & numerical data, Female, Glioblastoma/diagnosis, Glioblastoma/genetics, Glioblastoma/mortality, Glioblastoma/therapy, Humans, Isocitrate Dehydrogenase/genetics, Magnetic Resonance Imaging, Male, Positron-Emission Tomography/methods, Progression-Free Survival, Radiopharmaceuticals/administration & dosage, Tyrosine/administration & dosage, Tyrosine/analogs & derivatives

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32967939; info:eu-repo/semantics/altIdentifier/eissn/1557-3265; https://serval.unil.ch/notice/serval:BIB_9DF2F9C55BFBTest; urn:issn:1078-0432

الإتاحة: https://doi.org/10.1158/1078-0432.CCR-20-2096Test
https://serval.unil.ch/notice/serval:BIB_9DF2F9C55BFBTest

المؤلفون: Petersen, J K, Boldt, H B, Sørensen, M D, Blach, S, Dahlrot, R H, Hansen, S, Burton, M, Thomassen, M, Kruse, T, Poulsen, F R, Andreasen, L, Hager, H, Ulhøi, B P, Lukacova, S, Reifenberger, G, Kristensen, B W

المصدر: Petersen , J K , Boldt , H B , Sørensen , M D , Blach , S , Dahlrot , R H , Hansen , S , Burton , M , Thomassen , M , Kruse , T , Poulsen , F R , Andreasen , L , Hager , H , Ulhøi , B P , Lukacova , S , Reifenberger , G & Kristensen , B W 2021 , ' Targeted next-generation sequencing of adult gliomas for retrospective prognostic evaluation and up-front diagnostics ' , Neuropathology and Applied Neurobiology , vol. 47 , no. 1 , ....

مصطلحات موضوعية: Adolescent, Adult, Aged, 80 and over, Astrocytoma/diagnosis, Biomarkers, Tumor/genetics, Brain Neoplasms/diagnosis, Female, Glioblastoma/diagnosis, Glioma/diagnosis, High-Throughput Nucleotide Sequencing, Humans, Isocitrate Dehydrogenase/genetics, Male, Middle Aged, Mutation/genetics, Prognosis, Telomerase/genetics, Young Adult

العلاقة: https://pure.au.dk/portal/en/publications/379efaef-04f1-4ee0-8c04-659b0f23d6e0Test

الإتاحة: https://doi.org/10.1111/nan.12645Test
https://pure.au.dk/portal/en/publications/379efaef-04f1-4ee0-8c04-659b0f23d6e0Test

المساهمون: Junjeong Choi, Eun Young Lee, Kyung-Jin Shin, Yang-Ki Minn, Jieun Kim, Se Hoon Kim, Kim, Se Hoon, Shin, Kyoung Jin, Lee, Eun Young

مصطلحات موضوعية: Adult, Aged, 80 and over, Biomarkers, Tumor/genetics, Tumor/metabolism, Brain Neoplasms/diagnosis, Brain Neoplasms/genetics, Brain Neoplasms/metabolism, DNA Mutational Analysis, DNA, Neoplasm, Diagnostic Errors/prevention & control, Female, Glioma/diagnosis, Glioma/genetics, Glioma/metabolism, Humans, Isocitrate Dehydrogenase/genetics, Isocitrate Dehydrogenase/metabolism, Male, Middle Aged, Mutation, Peptide Nucleic Acids*/genetics, Polymerase Chain Reaction/methods, Reproducibility of Results, Isocitrate dehydrogenase (IDH) 1 mutation, Gliomas, Direct sequencing, Immunohistochemistry

العلاقة: PATHOLOGY RESEARCH AND PRACTICE; J02474; OAK-2013-00707; https://ir.ymlib.yonsei.ac.kr/handle/22282913/86825Test; http://www.sciencedirect.com/science/article/pii/S034403381300037XTest; T201301513; PATHOLOGY RESEARCH AND PRACTICE, Vol.209(5) : 284-290, 2013

الإتاحة: https://doi.org/10.1016/j.prp.2013.02.010Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/86825Test
http://www.sciencedirect.com/science/article/pii/S034403381300037XTest

المساهمون: Dakeun Lee, Yeon-Lim Suh, So Young Kang, Tae-In Park, Ji Yun Jeong, Se-Hoon Kim, Kim, Se Hoon

مصطلحات موضوعية: Brain Neoplasms/pathology, DNA, Neoplasm/genetics, Female, Humans, Immunohistochemistry, Isocitrate Dehydrogenase/genetics, Kaplan-Meier Estimate, Male, Mutation/genetics, Oligodendroglia/pathology, Peptide Nucleic Acids/chemistry, Polymerase Chain Reaction, Sequence Analysis, DNA/methods, Survival Analysis

العلاقة: BRAIN PATHOLOGY; J00391; OAK-2013-00650; https://ir.ymlib.yonsei.ac.kr/handle/22282913/86768Test; T201301322; BRAIN PATHOLOGY, Vol.23(3) : 285-293, 2013

الإتاحة: https://doi.org/10.1111/bpa.12000Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/86768Test

المساهمون: Ji Young Kim, Jae Yong Shin, Miri Kim, Seung-Kyung Hann, Sang Ho Oh, Kim, Miri, Oh, Sang Ho

مصطلحات موضوعية: Animals, Antioxidants/metabolism, Apoptosis, Blotting, Western, Cell Line, Cell Survival, Glutathione/metabolism, Humans, Isocitrate Dehydrogenase/genetics, Isocitrate Dehydrogenase/metabolism, Melanocytes/drug effects, Melanocytes/enzymology, Melanocytes/pathology, Mice, Necrosis, Oxidants/pharmacology, Oxidative Stress, RNA Interference, Reactive Oxygen Species/metabolism, Real-Time Polymerase Chain Reaction, Time Factors, Transfection, Vitiligo/enzymology, Cytosolic NADP+-dependent isocitrate dehydrogenase, siRNA, Oxidant stress, Antioxidant, Melanocyte, Vitiligo

العلاقة: JOURNAL OF DERMATOLOGICAL SCIENCE; J01370; OAK-2012-00367; https://ir.ymlib.yonsei.ac.kr/handle/22282913/90752Test; http://www.sciencedirect.com/science/article/pii/S0923181111003574Test; T201200564; JOURNAL OF DERMATOLOGICAL SCIENCE, Vol.65(2) : 118-125, 2012

الإتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/90752Test
http://www.sciencedirect.com/science/article/pii/S0923181111003574Test