نتائج البحث - "Ian C. Paterson"

41

Cell Cycle Arrest and Apoptosis Induction via Modulation of Mitochondrial Integrity by Bcl-2 Family Members and Caspase Dependence inDracaena cinnabari-Treated H400 Human Oral Squamous Cell Carcinoma

المؤلفون: Kai Li Lim, Rola Ali-Saeed, Bushra A. Muharram, Ian C. Paterson, Aied M. Alabsi

المصدر: BioMed Research International
BioMed Research International, Vol 2016 (2016)

مصطلحات موضوعية: 0301 basic medicine, Article Subject, lcsh:Medicine, Apoptosis, DNA Fragmentation, Phosphatidylserines, Chemical Fractionation, Mitochondrion, General Biochemistry, Genetics and Molecular Biology, S Phase, Inhibitory Concentration 50, 03 medical and health sciences, chemistry.chemical_compound, Annexin, Dracaena cinnabari, Humans, Neoplasms, Squamous Cell, DAPI, Cell Shape, Dracaena, Caspase, Cell Proliferation, Membrane Potential, Mitochondrial, General Immunology and Microbiology, biology, Plant Extracts, Cell growth, lcsh:R, Bcl-2 family, Cytochromes c, Cell Cycle Checkpoints, General Medicine, Fibroblasts, biology.organism_classification, Molecular biology, Mitochondria, Nucleosomes, 030104 developmental biology, Proto-Oncogene Proteins c-bcl-2, chemistry, Caspases, Immunology, biology.protein, Biological Assay, Mouth Neoplasms, Signal Transduction, Research Article

وصف الملف: text/xhtml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22fc86cbaf56de3707f0b05f07340adTest
https://doi.org/10.1155/2016/4904016Test

42

Profiling lysophosphatidic acid levels in plasma from head and neck cancer patients

المؤلفون: Mustafa Ali Mohd, Didi Erwandi Mohamad Haron, Ian C. Paterson, Munn Sann Lye, Saiful Anuar Karsani, Robert Hollows, Wen Lin Chai, Zuleen Delina Fasya Abdul Ghani, Ching Ching Ng, Lee Fah Yap, Mariati Abdul Rahman

المصدر: PeerJ, Vol 8, p e9304 (2020)
PeerJ

مصطلحات موضوعية: lcsh:Medicine, Biochemistry, General Biochemistry, Genetics and Molecular Biology, World health, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Triple quadrupole mass spectrometry, Lysophosphatidic acid, Lipidomics, Nasopharyngeal carcinoma, medicine, Basal cell, 030304 developmental biology, 0303 health sciences, business.industry, Oral cancer, General Neuroscience, lcsh:R, Head and neck cancer, General Medicine, medicine.disease, Head and neck squamous-cell carcinoma, stomatognathic diseases, Oncology, chemistry, 030220 oncology & carcinogenesis, Cancer research, lipids (amino acids, peptides, and proteins), biological phenomena, cell phenomena, and immunity, General Agricultural and Biological Sciences, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ff77ad4e66aef6b1b1a265f7a5902aTest
https://doi.org/10.7717/peerj.9304Test

43

Development of small molecule inhibitors targeting TGF-β ligand and receptor: Structures, mechanism, preclinical studies and clinical usage

المؤلفون: Xiaohong Sang, Yucheng Wang, Wei Hong, Hao Wang, Xinyi Yang, Xuefu You, Meiling Chen, Ian C. Paterson

المصدر: European Journal of Medicinal Chemistry. 191:112154

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d929c29c68aee6a03860d25e180d5deTest
https://doi.org/10.1016/j.ejmech.2020.112154Test

44

The development of a novel transforming growth factor-β (TGF-β) inhibitor that disrupts ligand-receptor interactions

المؤلفون: Hao Wang, Xuefu You, Ian C. Paterson, Yu Huang, Xinyi Yang, Yu Sun, Wei Hong, Jingyang Li, Wee Lin Wong, Han Wu, Jiajia Cui, Lee Fah Yap

المصدر: European Journal of Medicinal Chemistry. 189:112042

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962fe6db02f17aabce86e47d600985adTest
https://doi.org/10.1016/j.ejmech.2020.112042Test

45

The Dynamic Roles of TGF-β Signalling in EBV-Associated Cancers

المؤلفون: Christopher W. Dawson, Ian C. Paterson, Sharmila Velapasamy, Lee Fah Yap, Lawrence S. Young

المصدر: Cancers, Vol 10, Iss 8, p 247 (2018)
Cancers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4c5bea27ab5a0f8658799f3e6d2e44Test
http://www.mdpi.com/2072-6694/10/8/247Test

46

Clinico-pathological features of oropharyngeal squamous cell carcinomas in Malaysia with reference to HPV infection

المؤلفون: Anthony Rhodes, Phaik-Leng Cheah, Selvam Thavaraj, Lee Fah Yap, Pathmanathan Rajadurai, Max Robinson, Kin Choo Pua, Sook Ling Lai, Ian C. Paterson, Hans Prakash Sathasivam, Maizaton Atmadini Abdullah

المصدر: Infectious Agents and Cancer
Infectious Agents and Cancer, Vol 13, Iss 1, Pp 1-6 (2018)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65b58719698eed980cc0305c9f7030eTest
https://doi.org/10.1186/s13027-018-0193-6Test

47

In vitro functional evaluation of isolaureline, dicentrine and glaucine enantiomers at 5-HT

المؤلفون: Hui Li, Heng, Chin Fei, Chee, Chun Keng, Thy, Jia Ti, Tee, Sek Peng, Chin, Deron R, Herr, Michael J C, Buckle, Ian C, Paterson, Stephen W, Doughty, Noorsaadah, Abd Rahman, Lip Yong, Chung

المصدر: Chemical biologydrug design. 93(2)

مصطلحات موضوعية: Serotonin, Aporphines, Binding Sites, Stereoisomerism, Protein Structure, Tertiary, Molecular Docking Simulation, Kinetics, Structure-Activity Relationship, HEK293 Cells, Receptors, Adrenergic, alpha-1, Humans, Receptor, Serotonin, 5-HT2A, Adrenergic alpha-1 Receptor Agonists, Serotonin 5-HT2 Receptor Agonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::fac5a3ea6b3d03a0ee1c8cf2705fe69cTest
https://pubmed.ncbi.nlm.nih.gov/30216681Test

48

Cisplatin-Resistance in Oral Squamous Cell Carcinoma: Regulation by Tumor Cell-Derived Extracellular Vesicles

المؤلفون: Bey Hing Goh, Ian C. Paterson, Xin Hui Khoo, Wai Leng Lee

المصدر: Cancers
Volume 11
Issue 8
Cancers, Vol 11, Iss 8, p 1166 (2019)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1059bf7953cd57e525e4679e753b7cTest
https://doi.org/10.3390/cancers11081166Test

49

Comprehensive functional profiling of long non-coding RNAs through a novel pan-cancer integration approach and modular analysis of their protein-coding gene association networks

المؤلفون: Radmir Sarsenov, Wen Siong Too, Ian C. Paterson, Daniel W. Lambert, Stephen Brown, James R. Bradford, Roseanna K. Hare, Kevin Walters

المصدر: BMC Genomics
BMC Genomics, Vol 20, Iss 1, Pp 1-15 (2019)

مصطلحات موضوعية: 0106 biological sciences, lcsh:QH426-470, lcsh:Biotechnology, Functional profiling, Disease, Computational biology, Biology, Proteomics, 01 natural sciences, Extracellular matrix, 03 medical and health sciences, lncRNA, lcsh:TP248.13-248.65, Neoplasms, Gene expression, Genetics, Transcriptional regulation, medicine, Tumor Microenvironment, Humans, Gene Regulatory Networks, Epithelial–mesenchymal transition, RNA, Messenger, Gene, Genetic Association Studies, 030304 developmental biology, Cancer, 0303 health sciences, Tumour microenvironment, Gene Expression Profiling, Computational Biology, medicine.disease, Epithelial-mesenchymal transition, Phenotype, Gene Expression Regulation, Neoplastic, lcsh:Genetics, RNA, Long Noncoding, DNA microarray, Genes networks, Function (biology), 010606 plant biology & botany, Biotechnology, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36bd7077d79e0b80c9701f6df4fb706Test

50

The influence of glycerol on the binding of methotrexate toMycobacterium tuberculosisdihydrofolate reductase: a molecular modelling study

المؤلفون: Chang Zhe, Ian C. Paterson, Tao Sun, Jing Pu, Yu Wang, Hao Wang, Wei Hong

المصدر: Molecular Simulation. 41:1540-1545

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2be5a6c14d486101e55c3926e05089f1Test
https://doi.org/10.1080/08927022.2015.1048513Test

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