المؤلفون: V. Т. Ivashkin, I. V. Mayev, Р. V. Tsarkov, М. Р. Korolev, D. N. Andreev, Е. К. Baranskaya, D. S. Bordin, S. G. Burkov, А. А. Derinov, S. К. Efetov, Т. L. Lapina, Р. V. Pavlov, S. S. Pirogov, Е. А. Poluektova, А. V. Tkachev, А. S. Trukhmanov, А. I. Uljanin, Е. D. Fedorov, А. А. Sheptulin

المصدر: Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 34, Iss 2, Pp 101-131 (2024)

مصطلحات موضوعية: peptic ulcer, etiology, pathogenesis, diagnostics, treatment, Diseases of the digestive system. Gastroenterology, RC799-869

الوصف: Aim. The guidelines set out the modern methods of diagnostics and treatment of peptic ulcer and are created for gastroenterologists, primary care physicians, general practitioners, surgeons, endoscopists.Key points. The clinical guidelines contain modern views on the etiology and pathogenesis of peptic ulcer, its clinical features, methods of laboratory and instrumental diagnostics, the main approaches to conservative and surgical treatment. They include the criteria for assessment of the quality of medical care, the algorithm of the doctor's actions, as well as information for the patient.Conclusion. Knowledge of modern methods of diagnostics and therapy of peptic ulcers will contribute to improving the results of its treatment.

وصف الملف: electronic resource

العلاقة: https://www.gastro-j.ru/jour/article/view/1222Test; https://doaj.org/toc/1382-4376Test; https://doaj.org/toc/2658-6673Test

الوصول الحر: https://doaj.org/article/cb2307f2b4bf4db8bc4e1f45f519c7a0Test

المؤلفون: V. Т. Ivashkin, A. I. Ulyanin, I. V. Mayev, R. S. Kozlov, M. A. Livzan, S. R. Abdulkhakov, O. P. Alekseyeva, S. A. Alekseyenko, D. S. Bordin, N. N. Dekhnich, N. V. Korochyanskaya, T. L. Lapina, E. A. Poluektova, V. I. Simanenkov, A. S. Trukhmanov, I. B. Khlynov, V. V. Tsukanov, A. A. Sheptulin

المصدر: Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 32, Iss 6, Pp 7-19 (2023)

مصطلحات موضوعية: gastritis, gastric cancer, atrophy, h. pylori, eradication, compliance, microbiome, microbiota, antibiotics, probiotics, saccharomyces boulardii cncm i-745, Diseases of the digestive system. Gastroenterology, RC799-869

الوصف: Aim: to analyze current approaches to H. pylori eradication therapy in adults and present the materials of Experts Council held on December 9, 2022 in Moscow.General statements. H. pylori infection is the main etiological factor of gastritis, peptic ulcer, and gastric cancer. Eradication of H. pylori is recognized as a necessary measure to reduce the incidence of these diseases. The approaches to selecting an eradication regimen should be optimized to take into account epidemiological trends and achieve better treatment outcomes. The updated Maastricht VI Consensus Report presents the means to overcome the difficulties in selecting an approach to the treatment of H. pylori infection. However, eradication therapy remains challenging due to adverse events (primarily antibiotic-associated diarrhea), poor treatment tolerance and patient compliance. Eradication therapy can be optimized by supplementing treatment regimens with strain-specific probiotics that reduce adverse events, improve patient compliance and eradication rates, such as Saccharomyces boulardii CNCM I-745 strain with established efficacy.Conclusion. The inclusion of certain probiotics in eradication regimens improves treatment tolerance, reduces the risk of adverse events, improves patient compliance and eradication rates.

وصف الملف: electronic resource

العلاقة: https://www.gastro-j.ru/jour/article/view/800Test; https://doaj.org/toc/1382-4376Test; https://doaj.org/toc/2658-6673Test

الوصول الحر: https://doaj.org/article/36c3aad790b84e4e9531e6d5a14c83f6Test

المؤلفون: O. M. Drapkina, A. V. Kontsevaya, A. M. Kalinina, S. M. Avdeev, M. V. Agaltsov, L. M. Alexandrova, A. A. Antsiferova, D. M. Aronov, N. M. Akhmedzhanov, Yu. A. Balanova, T. V. Balakhonova, S. A. Berns, M. V. Bochkarev, E. V. Bochkareva, M. V. Bubnova, A. V. Budnevsky, M. G. Gambaryan, V. M. Gorbunov, B. E. Gorny, A. Yu. Gorshkov, N. G. Gumanova, V. A. Dadaeva, L. Yu. Drozdova, V. A. Egorov, S. O. Eliashevich, A. I. Ershova, E. S. Ivanova, A. E. Imaeva, P. V. Ipatov, A. D. Kaprin, N. S. Karamnova, Zh. D. Kobalava, A. O. Konradi, O. V. Kopylova, L. S. Korostovtseva, M. B. Kotova, M. S. Kulikova, E. A. Lavrenova, O. V. Lischenko, M. V. Lopatina, Yu. V. Lukina, M. M. Lukyanov, I. V. Mayev, M. N. Mamedov, S. V. Markelova, S. Yu. Martsevich, V. A. Metelskaya, A. N. Meshkov, O. Yu. Milushkina, D. K. Mukaneeva, A. O. Myrzamatova, D. V. Nebieridze, D. O. Orlov, E. A. Poddubskaya, M. V. Popovich, O. E. Popovkina, V. I. Potievskaya, G. G. Prozorova, Yu. S. Rakovskaya, O. P. Rotar, I. A. Rybakov, Yu. V. Sviryaev, I. A. Skripnikova, N. A. Skoblina, M. I. Smirnova, V. V. Starinsky, S. N. Tolpygina, E. V. Usova, Zh. V. Khailova, S. A. Shalnova, R. N. Shepel, V. N. Shishkova, I. S. Yavelov, B. U. Mardanov

المصدر: Кардиоваскулярная терапия и профилактика, Vol 21, Iss 4 (2022)

مصطلحات موضوعية: профилактика, хронические неинфекционные заболевания, национальное руководство, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

العلاقة: https://cardiovascular.elpub.ru/jour/article/view/3235Test; https://doaj.org/toc/1728-8800Test; https://doaj.org/toc/2619-0125Test

الوصول الحر: https://doaj.org/article/83300086b47843efba984b9a0791df00Test

المؤلفون: V. T. Ivashkin, I. V. Mayev, A. S. Trukhmanov, O. A. Storonova, S. A. Abdulkhakov, D. N. Andreev, D. S. Bordin, E. R. Valitova, I. L. Klyaritskaya, V. V. Krivoy, Yu. A. Kucheryavyi, T. L. Lapina, S. V. Morozov, O. A. Sablin, E. V. Semenikhina, Yu. P. Uspenskiy, A. A. Sheptulin

المصدر: Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 30, Iss 3, Pp 61-88 (2020)

مصطلحات موضوعية: high-resolution manometry, gastroesophageal reflux disease, achalasia, esophagospasm, dysphagia, chest pain, Diseases of the digestive system. Gastroenterology, RC799-869

الوصف: Aim. Current recommendations of the Russian Gastroenterological Association on clinical use of high-resolution manometry in diagnosis of esophageal disorders are intended to assist in clinical decision making, terminology standardisation and interpretation of clinical data.Key points. In 2018, a joint meeting of the Russian Gastroenterological Association and Russian Neurogastroenterology and Motility Group approved unified terminology and classification of esophageal motor function disorders for high-resolution manometry diagnosis.Gastrointestinal patient complaints typically concern esophageal disorders such as dysphagia, regurgitation, heart-burn, chest pain or belching. To exclude erosive and ulcerative lesions, eosinophilic esophagitis and organic changes, esophagogastroduodenoscopy and biopsy are recommended in pre-treatment. Upon excluding mucosal lesions and esophageal lumen obstruction as causal for symptoms, use of high-resolution manometry is recommended. This method of esophageal examination has become the “gold standard” in diagnosis of motor disorders.High-resolution manometry enables detailed investigation of integral quantitative and qualitative characteristics of esophagus motor function and specific related disorders, analysis of esophageal contractile propagation and strictly coordinated synchronous peristalsis of upper esophageal sphincter, esophagus and lower esophageal sphincter, which malfunction may provoke development of achalasia, esophagospasm, hiatal hernia, ineffective eso pha geal motility and other motor disorders.Conclusion. High-resolution manometry is a relatively new method for study of esophagus motor function gaining increasingly wide application in clinical practice. It enables a medical professional to obtain evidence that may critically affect the choice of optimal patient care strategy and effective treatment. Current recommendations are based on an extensive review of up-to-date information and will be updated with new corpus of clinical data and assessment emerging in evidential medicine to provide gastroenterologists country-wide with latest scientific and practical guidelines.

وصف الملف: electronic resource

العلاقة: https://www.gastro-j.ru/jour/article/view/488Test; https://doaj.org/toc/1382-4376Test; https://doaj.org/toc/2658-6673Test

الوصول الحر: https://doaj.org/article/3b58b62af4c44068aa10cc0c6f04aab4Test

المؤلفون: V. T. Ivashkin, I. V. Mayev, D. I. Abdulganieva, S. A. Alekseenko, N. Yu. Ivashkina, N. V. Korochanskaya, S. N. Mammaev, E. A. Poluektova, A. S. Trukhmanov, Yu. P. Uspensky, V. V. Tsukanov, O. S. Shifrin, O. Yu. Zolnikova, K. V. Ivashkin, T. L. Lapina, R. V. Maslennikov, A. I. Ulyanin

المصدر: Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 30, Iss 2, Pp 76-89 (2020)

مصطلحات موضوعية: probiotic, probiotic strain, acute diarrhea, antibiotic-associated diarrhea, c. difficile-associated disease, h. pylori eradication, inflammatory bowel disease, ulcerative colitis, crohn’s disease, pouchitis, irritable bowel syndrome, functional constipation, Diseases of the digestive system. Gastroenterology, RC799-869

الوصف: Aim. To provide practical recommendations on the use of probiotics for the treatment and prevention of gastroenterological diseases in adults.General provisions. Probiotics are living microorganisms that benefit the health of the host when administered in adequate amounts. The main functions of probiotics include the support for colonisation resistance, the metabolism of food substrates and utilisation of end metabolites, the production of substrates necessary for the macro-organism, as well as the regulation of local and adaptive immune responses. Probiotics can be registered in the Russian Federation as biologically active food additives (BAFA) or as pharmaceutical products (drugs) in accordance with the microbiological standards and legislative requirements of the Russian Federation. The probiotics registered in the Russian Federation as BAFA for adults include bacteria of the Lactobacillus, Bifidobacterium, Enterococcus, Pediococcus, Lactococcus, Streptococcus, Bacillus, and Escherichia genera, and fungi of the Saccharomyces genus; probiotics registered as drugs — bacteria of Lactobid, Lactobacid, Escherichia and Enterococcus genera and fungi of the Saccharomyces genus. Some probiotics registered in the Russian Federation include probiotic strains that have proved to be effective for the prevention and treatment of antibiotic-associated diarrhea, the prevention of C. difficile-associated disease, the eradication of H. pylori infection, as well as for the treatment of irritable bowel syndrome and functional constipation.Conclusions. The clinical efficacy of probiotics depends on the probiotic strains included in their composition and is confirmed by a comparative analysis of the results of appropriate clinical studies. Not all probiotics registered in the Russian Federation as BAFA or drugs contain bacterial or fungal strains; as a result, the expected clinical effect may not be achieved.

وصف الملف: electronic resource

العلاقة: https://www.gastro-j.ru/jour/article/view/478Test; https://doaj.org/toc/1382-4376Test; https://doaj.org/toc/2658-6673Test

الوصول الحر: https://doaj.org/article/68b42d7e6d0d4c5194f247b5484cb5ffTest

المؤلفون: A. I. Martynov, A. A. Sheptulin, I. V. Mayev, A. N. Kazyulin, A. Ye. Karateev, A. V. Melekhov, L. K. Pal’gova, K. L. Raikhel’son

المصدر: Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 30, Iss 2, Pp 7-14 (2020)

مصطلحات موضوعية: gastric and intestial mucosa, cytoprotection, rebamipid, Diseases of the digestive system. Gastroenterology, RC799-869

الوصف: Aim. To generalize up-to-date information on the possibilities of cytoprotection in the treatment and prevention of gastric and intestinal diseases, as well as to present the materials of an Expert Council meeting held on February 8, 2020 in Moscow under the support of the Alium company.General provisions. The conducted Expert Council meeting was aimed at discussing the importance of improving the cytoprotective properties of the gastric and intestinal mucous membrane in the treatment of its lesions. It was shown that Rebamipide exhibits positive effects on various parts of the protective barrier of the gastrointestinal tract (GIT), primarily due to its stimulating action on the production of prostaglandins playing a key role in maintaining the cytoprotective properties of the gastrointestinal mucosa. The possibilities of applying Rebamipide for the treatment and prevention of erosive and ulcerative gastrointestinal lesions caused by non-steroidal anti-inflammatory (NSAIDs) and antithrombotic drugs were demonstrated. In the treatment of gastroesophageal reflux disease, Rebamipide is recommended for patients refractory to therapy with proton pump inhibitors (PPIs) and for those with non-acid reflux. The efficacy of Rebamipide in the treatment of Helicobacter pylori (H. pylori) infection, as well as functional dyspepsia and chronic gastritis, was confirmed.Conclusions. Rebamipid is a highly effective drug positively affecting various cytoprotection links, thus being suitable for the treatment and prevention of erosive and ulcerative lesions of the gastrointestinal tract, as well as gastroenterological diseases of various etiologies.Conflict of interest: The Expert Council meeting was supported by the Alium company.

وصف الملف: electronic resource

العلاقة: https://www.gastro-j.ru/jour/article/view/477Test; https://doaj.org/toc/1382-4376Test; https://doaj.org/toc/2658-6673Test

الوصول الحر: https://doaj.org/article/75af2884c15e4d9fa9e6f4be2e80cefaTest

المؤلفون: V. T. Ivashkin, I. V. Mayev, A. D. Kaprin, M. Yu. Agapov, D. N. Andreev, A. S. Vodoleev, M. Yu. Zharkova, M. P. Korolev, Yu. A. Kucheryavyi, T. L. Lapina, M. V. Mayevskaya, A. V. Okhlobystin, Ch. S. Pavlov, A. V. Paraskevova, S. S. Pirogov, E. A. Poluektova, D. E. Rumyantseva, A. S. Trukhmanov, P. V. Tsarkov, A. A. Sheptulin, O. S. Shifrin

المصدر: Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 29, Iss 5, Pp 53-74 (2019)

مصطلحات موضوعية: esophageal adenocarcinoma, esophageal squamous cell carcinoma, gastric cancer, colorectal cancer, hepatocellular carcinoma and extrahepatic bile duct and gall bladder cancer, pancreatic cancer, Diseases of the digestive system. Gastroenterology, RC799-869

الوصف: Aim. The present guidelines intended for primary care physicians are aimed at facilitating early diagnosis of malignant tumours of the digestive system, which can significantly improve the immediate and long-term results of their treatment.General provisions. The guidelines comprise sections devoted to esophageal adenocarcinoma, esophageal squamous cell carcinoma, gastric cancer, colorectal cancer, hepatocellular carcinoma and extrahepatic bile duct and gall bladder cancer, as well as pancreatic cancer. Each section contains information on risk factors and precancerous diseases, which allows a physician to identify whether a particular patient falls into the risk group of digestive system neoplasms. It is shown how digestive system cancers can be suspected on the basis of patients’ complaints and past medical history, as well as data obtained both from a direct examination and laboratory instrumental studies. Each section offers practical algorithms in cases of suspected esophageal adenocarcinoma, esophageal squamous cell carcinoma, gastric cancer, colorectal cancer, hepatocellular carcinoma and extrahepatic bile duct and gallbladder cancer, as well as pancreatic cancer.Conclusion. The knowledge of clinical manifestations and risk factors in the development of digestive system neoplasms allows a physician to suspect cancer and devise a timely and adequate diagnostic strategy, including laboratory and instrumental studies at specialised clinical centres.

وصف الملف: electronic resource

العلاقة: https://www.gastro-j.ru/jour/article/view/422Test; https://doaj.org/toc/1382-4376Test; https://doaj.org/toc/2658-6673Test

الوصول الحر: https://doaj.org/article/92a0fe480912482eaf9b49d7cb3a3669Test

المؤلفون: V. T. Ivashkin, Yu. A. Shelygin, Ye. K. Baranskaya, Ye. A. Belousova, A. G. Beniashvili, S. V. Vasilyev, A. O. Golovenko, O. V. Golovenko, Ye. G. Grigoryev, N. V. Kostenko, T. L. Lapina, I. D. Loranskaya, O. S. Lyashenko, I. V. Mayev, Ye. A. Poluektova, V. G. Rumyantsev, V. M. Timerbulatov, A. S. Trukhmanov, O. Yu. Fomenko, I. L. Khalif, E. Yu. Chashkova, A. A. Sheptulin, O. S. Shifrin, V. V. Yanovoy

المصدر: Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 27, Iss 5, Pp 76-93 (2018)

مصطلحات موضوعية: синдром раздраженного кишеч-ника, диарея, запор, спазмолитики, лоперамида гидрохлорид, диоктаэдрический смектит, пробио-тики, слабительные средства, прукалоприд, триме-бутина малеат, stw5, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

العلاقة: https://www.gastro-j.ru/jour/article/view/184Test; https://doaj.org/toc/1382-4376Test; https://doaj.org/toc/2658-6673Test

الوصول الحر: https://doaj.org/article/62a2600e038940bc94c51ffa3277975eTest

المؤلفون: V. T. Ivashkin, I. V. Mayev, A. A. Sheptulin, T. L. Lapina, A. S. Trukhmanov, I. M. Kartavenko, V. A. Kiprianis, O. Z. Okhlobystina

المصدر: Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 27, Iss 1, Pp 50-61 (2018)

مصطلحات موضوعية: диспепсия, функциональная диспепсия, органическая диспепсия, хронический гастрит, инфекция helicobacter pylori, эрадикация, Diseases of the digestive system. Gastroenterology, RC799-869

الوصف: The aim of publication. To present the modern concept on etiology and pathogenesis of functional dyspepsia (FD) to general practitioners, as well as with the accepted approach to diagnostics and treatment of this disease. Summary. FD is the most common digestive disease. It’s etiology includes genetic predisposition, bad habits, previous intestinal infections, psychosocial factors. The basic pathogenic factors may include HCl hypersecretion, stomach and duodenal dysmotility and visceral hypersensitivity. FD diagnosis should be established after ruling out of the organic diseases that may manifest by dyspepsia. Treatment is based on the stepwise approach, that includes general procedures, application of the drugs reducing hydrochloric acid secretion and normalizing motility and visceral sensitivity of the stomach and duodenum, in difficult to treat cases - psychopharmacological drugs and psychotherapeutic methods. Conclusion. Following of the functional dyspepsia management algorithm allows to increase the accuracy of FD diagnosis and improve treatment results.

وصف الملف: electronic resource

العلاقة: https://www.gastro-j.ru/jour/article/view/123Test; https://doaj.org/toc/1382-4376Test; https://doaj.org/toc/2658-6673Test

الوصول الحر: https://doaj.org/article/31472f99bf7a46d8aae5d998edd9f248Test

المؤلفون: V. T. Ivashkin, A. S. Trukhmanov, E. A. Godzhello, I. V. Mayev, Yu. V. Evsyutina, T. L. Lapina, O. A. Storonova

المصدر: Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 26, Iss 4, Pp 36-54 (2018)

مصطلحات موضوعية: ахалазия кардии, кардиоспазм, нижний пищеводный сфинктер, мано-метрия высокого разрешения, мегаэзофагус, дискинезия грудного отдела пищевода, боль в грудной клетке, эзофагит, рак пищевода, кардиодилатация, кардиомиотомия, диагностика, лечение, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

العلاقة: https://www.gastro-j.ru/jour/article/view/70Test; https://doaj.org/toc/1382-4376Test; https://doaj.org/toc/2658-6673Test

الوصول الحر: https://doaj.org/article/34dcd153476e464097daf6c255bff210Test