نتائج البحث - "Hussein Abdul-Hassan Tawbi"

91

Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial

المصدر: The Lancet. Oncology. 18(11)

مصطلحات موضوعية: 0301 basic medicine, Leiomyosarcoma, Adult, Male, medicine.medical_specialty, Maximum Tolerated Dose, Bone Neoplasms, Soft Tissue Neoplasms, Pembrolizumab, Kaplan-Meier Estimate, Bone Sarcoma, Antibodies, Monoclonal, Humanized, Undifferentiated Pleomorphic Sarcoma, Disease-Free Survival, Drug Administration Schedule, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Confidence Intervals, Humans, Neoplasm Invasiveness, Infusions, Intravenous, Aged, Neoplasm Staging, Academic Medical Centers, Dose-Response Relationship, Drug, business.industry, Soft tissue sarcoma, Sarcoma, Middle Aged, medicine.disease, Prognosis, Survival Analysis, Synovial sarcoma, United States, Surgery, 030104 developmental biology, Treatment Outcome, Oncology, Response Evaluation Criteria in Solid Tumors, 030220 oncology & carcinogenesis, Female, Patient Safety, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab2a414258fcf9d4baa15e0b218a93aTest
https://pubmed.ncbi.nlm.nih.gov/29304368Test

92

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma

المؤلفون: Haven R. Garber, Xingzhi Song, Padmanee Sharma, Alexandria P. Cogdill, Brett W. Carter, Robert Sloane, Jeffrey E. Gershenwald, Xizeng Mao, Zachary A. Cooper, Mariana Petaccia de Macedo, Christine N. Spencer, Jacob Austin-Breneman, Michael A. Davies, Jason Roszik, Ignacio I. Wistuba, Hannah C. Beird, P. Andrew Futreal, Karen Clise-Dwyer, Rodabe N. Amaria, Peter A. Prieto, Curtis Gumbs, James P. Allison, Hong Jiang, Alexandre Reuben, Luigi Nezi, Alexander J. Lazar, Cara Haymaker, Jianhua Hu, Jianhua Zhang, Sapna Pradyuman Patel, Adi Diab, Sangeetha M. Reddy, Rebecca Thornton, Elizabeth A. Grimm, Scott E. Woodman, Latasha Little, Hussein Abdul-Hassan Tawbi, Courtney W. Hudgens, Marie Andrée Forget, Patrick Hwu, Pei Ling Chen, Michael T. Tetzlaff, Jiong Chen, Wei Shen Chen, Isabella C. Glitza, Lynda Chin, Chantale Bernatchez, Jennifer A. Wargo, Jeffrey E. Lee, Vancheswaran Gopalakrishnan, Khalida Wani, Eveline Chen, John P. Miller, Whijae Roh

المصدر: NPJ Genomic Medicine
npj Genomic Medicine, Vol 2, Iss 1, Pp 1-11 (2017)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8886a0a09e16d4f6247dea11f14c8bf0Test
http://europepmc.org/articles/PMC5557036Test

93

Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance

المصدر: Science Translational Medicine. 9

مصطلحات موضوعية: 0301 basic medicine, Melanoma, T-cell receptor, General Medicine, Drug resistance, Biology, medicine.disease, Article, Immune checkpoint, Blockade, 03 medical and health sciences, 030104 developmental biology, CTLA-4, Immunology, medicine, Cytotoxic T cell, Biomarker (medicine)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383ec8dcff41f970ae280abccb2b2845Test
https://doi.org/10.1126/scitranslmed.aah3560Test

94

Radiation necrosis with stereotactic radiosurgery combined with CTLA-4 blockade and PD-1 inhibition for treatment of intracranial disease in metastatic melanoma

المؤلفون: Hussein Abdul-Hassan Tawbi, Jack Phan, Wen Jiang, Amol J. Ghia, Patrick Hwu, Anita Mahajan, Penny Fang, Pamela K. Allen, Jing Li, Isabella C. Glitza, Nandita Guha

المصدر: Journal of neuro-oncology. 133(3)

مصطلحات موضوعية: Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Adolescent, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Ipilimumab, Radiosurgery, Targeted therapy, 03 medical and health sciences, Necrosis, Young Adult, 0302 clinical medicine, Antineoplastic Agents, Immunological, Internal medicine, parasitic diseases, medicine, Humans, CTLA-4 Antigen, Radiation Injuries, Melanoma, Aged, Retrospective Studies, Aged, 80 and over, Chemotherapy, Proportional hazards model, business.industry, Brain Neoplasms, Cancer, Retrospective cohort study, Middle Aged, medicine.disease, Combined Modality Therapy, Surgery, Neurology, 030220 oncology & carcinogenesis, Female, Neurology (clinical), Immunotherapy, business, 030217 neurology & neurosurgery, medicine.drug, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c161fdc400447afb8cbb8175232dc2Test
https://pubmed.ncbi.nlm.nih.gov/28500560Test

95

Abstract 1493: Therapeutic efficacy and tolerability of combined immune checkpoint blockade in metastatic melanoma patients is influenced by the gut microbiome

المصدر: Cancer Research. 79:1493-1493

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, business.industry, medicine.medical_treatment, Cancer, medicine.disease, Primary tumor, Immune checkpoint, Blockade, Immune system, Cancer immunotherapy, Tolerability, Internal medicine, Medicine, business, Adverse effect

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1ce85ab86bae96b2ca7ef93c0a63faa5Test
https://doi.org/10.1158/1538-7445.am2019-1493Test

96

Abstract 2838: The gut microbiome (GM) and immunotherapy response are influenced by host lifestyle factors

المصدر: Cancer Research. 79:2838-2838

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1b8e489b175c30c29009ffd14c394055Test
https://doi.org/10.1158/1538-7445.am2019-2838Test

97

Abstract 499: NanoString®GeoMx®digital spatial profiling further defines the role of B cells in the response to immune checkpoint blockade

المصدر: Cancer Research. 79:499-499

مصطلحات موضوعية: Cancer Research, Follicular dendritic cells, biology, business.industry, medicine.medical_treatment, Melanoma, Immunotherapy, Acquired immune system, medicine.disease, Immune checkpoint, CD19, Immune system, medicine.anatomical_structure, Oncology, Cancer research, biology.protein, Medicine, business, B cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::fa40b1b7ecb13988270205e903ed898fTest
https://doi.org/10.1158/1538-7445.am2019-499Test

98

Abstract 4488: Effector B cells and tertiary lymphoid structures predict response to immune checkpoint blockade in solid tumors

المصدر: Cancer Research. 79:4488-4488

مصطلحات موضوعية: Cancer Research, Effector, Melanoma, Biology, medicine.disease, Immune checkpoint, Transcriptome, medicine.anatomical_structure, Oncology, medicine, Cancer research, Cytotoxic T cell, Immunohistochemistry, Mass cytometry, B cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::9245fe2a99bb44bec67c3d10b77f83d9Test
https://doi.org/10.1158/1538-7445.am2019-4488Test

99

Real-world outcomes with immuno-oncology (IO) therapies: A prospective, observational cohort study in patients (pts) with advanced melanoma (OPTIMIzE)

المؤلفون: Corey Ritchings, John M. Kirkwood, Rosa Wang, Yin Wan, Lisa A. Kottschade, Scott D. Ramsey, Hussein Abdul-Hassan Tawbi, Sekwon Jang, Sumati Rao, Robert R. McWilliams, Sigrun Hallmeyer, Nikhil I. Khushalani, David F. McDermott

المصدر: Journal of Clinical Oncology. 37:e14144-e14144

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, business.industry, hemic and lymphatic diseases, Internal medicine, Real world outcomes, Medicine, In patient, business, Cohort study, Advanced melanoma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3e209fa35c4e3d72d069e7fd2d226186Test
https://doi.org/10.1200/jco.2019.37.15_suppl.e14144Test

100

Clinical activity of pembrolizumab (P) in undifferentiated pleomorphic sarcoma (UPS) and dedifferentiated/pleomorphic liposarcoma (LPS): Final results of SARC028 expansion cohorts

المصدر: Web of Science

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03c782d30ad82bc8111d379821cf589Test
https://doi.org/10.1200/jco.2019.37.15_suppl.11015Test

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