المؤلفون: Christina S. Leslie, A. Cardenas, S. Leppanen, Rohit Chandwani, Lance Zhang, Smrita Sinha, S. Laderman, Danielle C. Glassman, Sagar Chhangawala, V. Aveson, Nicolas Lecomte, Steven D. Leach, D. Torres, Vinod P. Balachandran, Jiang Gui, Surajit Dhara, Richard A. Moffitt, Kenneth H. Yu, Alvin Makohon-Moore, B. Curry, Gokce Askan, Rémy Nicolle, H. Chintalapudi, Christine A. Iacobuzio-Donahue, A. L. Massa, Jonathan Bermeo, Jerry P. Melchor

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)

مصطلحات موضوعية: 0301 basic medicine, Microarray, Science, Kruppel-Like Transcription Factors, General Physics and Astronomy, Biology, Chromatin structure, General Biochemistry, Genetics and Molecular Biology, DNA sequencing, Article, Tumour biomarkers, 03 medical and health sciences, 0302 clinical medicine, Text mining, Pancreatic cancer, medicine, Biomarkers, Tumor, Humans, Transcription factor, Hepatocyte Nuclear Factor 1-beta, Regulation of gene expression, Cell Nucleus, Multidisciplinary, business.industry, High-Throughput Nucleotide Sequencing, General Chemistry, medicine.disease, HNF1B, Prognosis, Chromatin, Pancreatic Neoplasms, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Chromatin Immunoprecipitation Sequencing, business, Transcriptome, Carcinoma, Pancreatic Ductal, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a83add7cde624ad24db43f48b5d954dTest
https://pubmed.ncbi.nlm.nih.gov/34031415Test

المؤلفون: Neil A J Ryan, Anie Naqvi, D. Gareth Evans, Miriam J. Smith, Artitaya Lophatananon, Deborah J. Thompson, Cemsel Bafligil, Emma J Crosbie

المساهمون: Bafligil, Cemsel [0000-0002-2365-1194], Smith, Miriam J [0000-0002-3184-0817], Evans, D Gareth [0000-0002-8482-5784], Crosbie, Emma J [0000-0003-0284-8630], Apollo - University of Cambridge Repository

المصدر: Bafligil, C, Thompson, D J, Lophatananon, A, Smith, M J, Ryan, N A, Naqvi, A, Evans, D G & Crosbie, E J 2020, ' Association between genetic polymorphisms and endometrial cancer risk : a systematic review ', Journal of Medical Genetics, vol. 57, no. 9, pp. 591-600 . https://doi.org/10.1136/jmedgenet-2019-106529Test

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, genetic epidemiology, MEDLINE, Kruppel-Like Transcription Factors, Single-nucleotide polymorphism, CINAHL, Polymorphism, Single Nucleotide, SOXC Transcription Factors, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, eIF-2 Kinase, risk prediction, 0302 clinical medicine, Aromatase, single nucleotide polymorphism (SNP), systematic review, Risk Factors, Internal medicine, Genetics, medicine, Humans, Genetic Predisposition to Disease, Prospective Studies, Genetics (clinical), Genetic association, Hepatocyte Nuclear Factor 1-beta, business.industry, Endometrial cancer, Proto-Oncogene Proteins c-mdm2, Publication bias, medicine.disease, HNF1B, Endometrial Neoplasms, 030104 developmental biology, Genetic epidemiology, 030220 oncology & carcinogenesis, endometrial cancer, Female, business, Genome-Wide Association Study

وصف الملف: application/pdf; text/xml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee15bcd69b901ec9862311789699c611Test
https://hdl.handle.net/1983/faaa9e93-3941-414e-be4d-47375c96fd36Test

المؤلفون: Fei Wang, Kai Li, Jian Sun, Jianqing Wang, Chunchun Zhao, Wei Lu, Guanxiong Ding, Huihui Zhou, Caibin Fan

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Male, HNF1B, Smad6 Protein, proliferation, Biology, 03 medical and health sciences, Prostate cancer, CDKN2A, 0302 clinical medicine, Cyclin D1, SMAD6, Cell Line, Tumor, medicine, Humans, Psychological repression, Cyclin-Dependent Kinase Inhibitor p16, Cell Proliferation, Hepatocyte Nuclear Factor 1-beta, Effector, Cell growth, EZH2, Prostatic Neoplasms, Cell Biology, Original Articles, medicine.disease, prostate cancer, Immunohistochemistry, Gene Expression Regulation, Neoplastic, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Molecular Medicine, Original Article, G1 phase, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4d01bc521a589a4c6832ff4dff9874Test
https://pubmed.ncbi.nlm.nih.gov/33174391Test

المؤلفون: Sophia M. Vrba, Siu Chiu Chan, Sachin Hajarnis, Vishal Patel, Peter Igarashi

المصدر: J Biol Chem

مصطلحات موضوعية: 0301 basic medicine, Lymphoid Enhancer-Binding Factor 1, Kidney, Biochemistry, digestive system, Methylation, Histones, 03 medical and health sciences, Mice, Axin Protein, Wnt3A Protein, AXIN2, Animals, Gene Regulation, Regulatory Elements, Transcriptional, RNA, Small Interfering, Enhancer, Promoter Regions, Genetic, Molecular Biology, Transcription factor, Wnt Signaling Pathway, beta Catenin, Hepatocyte Nuclear Factor 1-beta, Cystic kidney, Mice, Knockout, Binding Sites, 030102 biochemistry & molecular biology, Chemistry, Wnt signaling pathway, Promoter, Epithelial Cells, Cell Biology, Cell biology, Hepatocyte nuclear factors, 030104 developmental biology, Gene Expression Regulation, Mutagenesis, embryonic structures, RNA Interference, Lymphoid enhancer-binding factor 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0949096a3aefdf33912c67d2377e64Test
https://pubmed.ncbi.nlm.nih.gov/33453998Test

المؤلفون: Tian Tao, Yuan Yang, Zhangxue Hu

المصدر: Medicine

مصطلحات موضوعية: Male, medicine.medical_specialty, HNF1B, Heterozygote, Mutation, Missense, Renal function, Aftercare, Hyperuricemia, Kidney, Gastroenterology, Maturity onset diabetes of the young, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Central Nervous System Diseases, Internal medicine, Renal fibrosis, Medicine, Humans, Hypoglycemic Agents, 030212 general & internal medicine, Clinical Case Report, Dental Enamel, Hydronephrosis, Hepatocyte Nuclear Factor 1-beta, Ultrasonography, ADTKD, business.industry, MODY5, High-Throughput Nucleotide Sequencing, General Medicine, Kidney Diseases, Cystic, medicine.disease, Renal dysplasia, Metformin, Pedigree, Diabetes Mellitus, Type 2, 030220 oncology & carcinogenesis, Hyperglycemia, Nephritis, Interstitial, Kidney stones, business, Multiple renal cysts, Kidney disease, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df27bbb537c9c5e76c50f7e74fbfdc3cTest
https://pubmed.ncbi.nlm.nih.gov/32756155Test

المؤلفون: Clara Si Hua Tan, Su Fen Ang, Ester Yeoh, Bing Xing Goh, Wann Jia Loh, Cheuk Fan Shum, Molly May Ping Eng, Allen Yan Lun Liu, Lovynn Wan Ting Chan, Li Xian Goh, Tavintharan Subramaniam, Chee Fang Sum, Su Chi Lim

المصدر: Journal of Investigative Medicine High Impact Case Reports, Vol 10 (2022)
Journal of Investigative Medicine High Impact Case Reports

مصطلحات موضوعية: Singapore, Medicine (General), HNF1B-MODY, Not an AFMR Member, Epidemiology, MODY5, renal anomalies, Case Report, renal trajectory, Kidney Diseases, Cystic, R5-920, Diabetes Mellitus, Type 2, Pathology, Humans, RB1-214, HNF1B-associated nephropathy, Safety, Risk, Reliability and Quality, Referral and Consultation, Safety Research, Hepatocyte Nuclear Factor 1-beta

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f7f5707a50048571c41918a800e10bTest
https://doi.org/10.1177/23247096211065626Test

المؤلفون: Cirovic, Branko, de Bree, L. Charlotte J., Schulte-Schrepping, Jonas, Klee, Kathrin, Oosting, Marije, Koeken, Valerie A. C. M., van Ingen, Jakko, Li, Yang, Benn, Christine S., Schultze, Joachim L., Joosten, Leo A. B., Curtis, Nigel, Groh, Laszlo, Netea, Mihai G., Schlitzer, Andreas, Blok, Bas A., Chan, Joyce, van der Velden, Walter J. F. M., Bremmers, M. E. J., van Crevel, Reinout, Händler, Kristian, Picelli, Simone

المصدر: Cell host and microbe 28(2), 322 - 334.e5 (2020). doi:10.1016/j.chom.2020.05.014

مصطلحات موضوعية: info:eu-repo/classification/ddc/570, BCG Vaccine: immunology, Bone Marrow: immunology, Bone Marrow Cells: cytology, Bone Marrow Cells: immunology, Cytokines: metabolism, Female, Granulocytes: cytology, Healthy Volunteers, Hematopoiesis: immunology, Hematopoietic Stem Cells: cytology, Hepatocyte Nuclear Factor 1-alpha: genetics, Hepatocyte Nuclear Factor 1-beta: genetics, Humans, Lipopolysaccharide Receptors: metabolism, Male, Monocytes: cytology, Monocytes: immunology, Mycobacterium bovis: immunology, Transcription, Genetic: genetics, Transcriptome: genetics, Vaccination, Young Adult, alpha 1-Antitrypsin: blood

جغرافية الموضوع: DE

العلاقة: info:eu-repo/semantics/altIdentifier/issn/1931-3128; info:eu-repo/semantics/altIdentifier/pmid/pmid:32544459; info:eu-repo/semantics/altIdentifier/issn/1934-6069; https://pub.dzne.de/record/153389Test; https://pub.dzne.de/search?p=id:%22DZNE-2020-01386%22Test

الإتاحة: https://doi.org/10.1016/j.chom.2020.05.014Test
https://pub.dzne.de/record/153389Test
https://pub.dzne.de/search?p=id:%22DZNE-2020-01386%22Test

المؤلفون: Shen, H., Fridley, B., Song, H., Lawrenson, K., Cunningham, J., Ramus, S., Cicek, M., Tyrer, J., Stram, D., Larson, M., Köbel, M., PRACTICAL Consortium, Ziogas, A., Zheng, W., Yang, H., Wu, A., Wozniak, E., Ling Woo, Y., Winterhoff, B., Wik, E.

المصدر: http://dx.doi.org/10.1038/ncomms2629Test.

مصطلحات موضوعية: PRACTICAL Consortium, Australian Ovarian Cancer Study Group, Australian Cancer Study, Humans, Ovarian Neoplasms, Genetic Predisposition to Disease, Gene Expression Profiling, DNA Methylation, Epigenesis, Genetic, Polymorphism, Single Nucleotide, Female, Hepatocyte Nuclear Factor 1-beta, Promoter Regions

وصف الملف: application/pdf

العلاقة: http://purl.org/au-research/grants/nhmrc/199600Test; http://purl.org/au-research/grants/nhmrc/400281Test; Nature Communications, 2013; 4(1):1628-1-1628-10; http://hdl.handle.net/2440/93645Test

الإتاحة: https://doi.org/10.1038/ncomms2629Test
http://hdl.handle.net/2440/93645Test

المؤلفون: Mareike M. Wiedmann, Murray Stewart, Shintaro Aibara, James D. Brenton, David R. Spring

المساهمون: Spring, David [0000-0001-7355-2824], Brenton, James [0000-0002-5738-6683], Apollo - University of Cambridge Repository

المصدر: Journal of Structural Biology

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, 0301 basic medicine, mImportin-α, mouse Importin-α, Nuclear Localization Signals, Nuclear import pathway, Xenopus Proteins, Crystallography, X-Ray, environment and public health, GST, glutathione S-transferase, HNF1βDBD, HNF1β DNA binding domain, Mice, Xenopus laevis, 0302 clinical medicine, Sequence Analysis, Protein, Structural Biology, Nuclear protein, CCC, ovarian clear cell carcinoma, IBB, Importin-β-binding domain, Hepatocyte nuclear factor-1β (HNF1β), Nuclear localisation signal sequence (NLS), 3. Good health, Cell biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Isothermal titration calorimetry, Protein Binding, alpha Karyopherins, Active Transport, Cell Nucleus, Importin, Biology, Article, HNF1β, hepatocyte nuclear factor 1β, 03 medical and health sciences, Importin-α, Cell Line, Tumor, medicine, Animals, Humans, Transcription factor, Hepatocyte Nuclear Factor 1-beta, X-ray crystallography, Cell Nucleus, Site-directed mutagenesis, Binding Sites, xImportin-α, Xenopus Importin-α, DNA-binding domain, Molecular biology, Cell nucleus, HEK293 Cells, 030104 developmental biology, NLS, nuclear localization signal, Hepatocyte Nuclear Factor 1-Beta, Nuclear transport, Nuclear localization sequence

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07cdc136a8a8b67b570e14b2d6984d3fTest

المؤلفون: Ludovic Vallier, R El-Khairi

المصدر: Diabetes, Obesity and Metabolism. 18:23-32

مصطلحات موضوعية: 0301 basic medicine, Heterozygote, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, medicine.disease_cause, Mice, 03 medical and health sciences, Liver disease, 0302 clinical medicine, Endocrinology, Internal Medicine, Animals, Humans, Medicine, Pancreas, Hepatocyte Nuclear Factor 1-beta, Mutation, business.industry, Gene Expression Regulation, Developmental, Kidney Diseases, Cystic, HNF1B, medicine.disease, Phenotype, Disease Models, Animal, Hepatocyte nuclear factors, 030104 developmental biology, Diabetes Mellitus, Type 2, Liver, Hepatocyte nuclear factor 4 alpha, Hepatocyte Nuclear Factor 1-Beta, Cancer research, business, Haploinsufficiency

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ae1252b967abcd0a4d64f4df7785aeTest
https://doi.org/10.1111/dom.12715Test