المؤلفون: Christian H. Haering, René H. Medema, Hans Teunissen, Ahmed M.O. Elbatsh, Robin H. van der Weide, Sol Bravo, Jonne A. Raaijmakers, Jelmi uit de Bos, Benjamin D. Rowland, Elzo de Wit

مصطلحات موضوعية: Genetics, Mutation, biology, Condensin, macromolecular substances, medicine.disease_cause, Cell biology, Chromosome segregation, Mitotic chromosome condensation, chemistry.chemical_compound, Prophase, chemistry, Premature chromosome condensation, biology.protein, medicine, Sister chromatids, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0ef008ff3e6560a4a04cd90fac0fbdTest

المؤلفون: Ran Elkon, Eric Pintó Barberà, Dannys Jorge Martínez-Herrera, Reuven Agami, Maite Huarte, Alejandro Pineiro Ugalde, Ruiqi Han, Naama Messika-Gold, Li Li, Rui Lopes, Pieter C van Breugel, Gozde Korkmaz, Elzo de Wit, Jarno Drost, Ricardo J Soares, Hans Teunissen, Annita Louloupi, Boye Schnack Nielsen, Kim Holmstrøm, Fabricio Loayza-Puch

المساهمون: Molecular Genetics

المصدر: Nucleic Acids Research
Nucleic Acids Research, 46(8), 4213-4227. Oxford University Press

مصطلحات موضوعية: 0301 basic medicine, Senescence, Dipeptidyl Peptidase 4, Gene Expression, Biology, medicine.disease_cause, 03 medical and health sciences, RNA interference, Neoplasms, Gene expression, Genetics, medicine, RNA and RNA-protein complexes, Gene silencing, Humans, Cellular Senescence, Gene knockdown, Genome, Oncogene, Cell biology, 030104 developmental biology, Genes, ras, HEK293 Cells, Ectopic expression, RNA, Long Noncoding, Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8257f2f707b429a33cc602f5d798514cTest
https://pubmed.ncbi.nlm.nih.gov/29481642Test

المؤلفون: Robert G.J. Vries, Albert J. R. Heck, Pantelis Hatzis, Tokameh Mahmoudi, Nadia Taouatas, Vivian S. W. Li, Hans Clevers, Hans Teunissen, Sylvia F. Boj, Harry Begthel, Jeroen Korving, Shabaz Mohammed

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: PLoS Biology, 8(11). Public Library of Science
PLoS Biology
PLoS Biology, Vol 8, Iss 11, p e1000539 (2010)

مصطلحات موضوعية: Beta-catenin, Transcription, Genetic, QH301-705.5, Oncology/Gastrointestinal Cancers, Gastroenterology and Hepatology/Small Intestine, General Biochemistry, Genetics and Molecular Biology, Cell Line, Mice, Transcription Factor 4, Intestine, Small, Animals, Homeostasis, Humans, Biology (General), Transcription factor, Cell Biology/Gene Expression, Zebrafish, beta Catenin, Cell Proliferation, Regulation of gene expression, Leukemia, General Immunology and Microbiology, biology, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Reverse Transcriptase Polymerase Chain Reaction, General Neuroscience, Molecular Biology/Transcription Elongation, Wnt signaling pathway, Correction, LRP6, LRP5, Histone-Lysine N-Methyltransferase, Methyltransferases, DNA Methylation, Developmental Biology/Stem Cells, Catenin, DNA methylation, Cancer research, biology.protein, General Agricultural and Biological Sciences, Biochemistry/Transcription and Translation, Research Article, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3e12c4305daee57f3a10d4a6859fdcTest
https://doi.org/10.1371/journal.pbio.1000539Test

المؤلفون: Mark Janssen, Patrick J. Wijchers, Hans Teunissen, Annette Denker, Carlo Vermeulen, Marjon J.A.M. Verstegen, Pernette J. Verschure, Christian Valdes-Quezada, Yun Zhu, Lisette C M Anink-Groenen, Geert Geeven, Peter H.L. Krijger, Wouter de Laat

المساهمون: Synthetic Systems Biology (SILS, FNWI), Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Molecular Cell, 61(3), 461. Cell Press
Molecular Cell, 61(3), 461-473. Cell Press
Molecular Cell
Molecular Cell, 61(3), 461-73. Cell Press

مصطلحات موضوعية: 0301 basic medicine, Cis effect, 129 Strain, Inbred C57BL, Genome, Chromosome segregation, Mice, Chromosome Segregation, Lac Repressors, Non-U.S. Gov't, Cells, Cultured, Genetics, Regulation of gene expression, Cultured, biology, Research Support, Non-U.S. Gov't, Polycomb Repressive Complex 2, Nanog Homeobox Protein, Chromatin, Cell biology, Histone, medicine.anatomical_structure, Lac Operon, Mice, 129 Strain, Cells, Research Support, Transfection, Article, 03 medical and health sciences, medicine, Journal Article, Animals, Enhancer of Zeste Homolog 2 Protein, Molecular Biology, Embryonic Stem Cells, Cell Nucleus, Homeodomain Proteins, Methyltransferases, Cell Biology, Chromatin Assembly and Disassembly, Mice, Inbred C57BL, Repressor Proteins, Cell nucleus, 030104 developmental biology, Gene Expression Regulation, Genetic Loci, biology.protein

وصف الملف: image/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af26e9298a62ed19f0aac4b9b9189b9dTest
https://dspace.library.uu.nl/handle/1874/346673Test

المؤلفون: A. Zantema, Hans Teunissen, Raoul C.M. Hennekam, Eric Kalkhoven, Jeroen H. Roelfsema, Martijn H. Breuning, Dorien J.M. Peters, Yavuz Ariyurek, Annemieke den Boer

المساهمون: Paediatric Genetics

المصدر: Human molecular genetics, 12(4), 441-450. Oxford University Press

مصطلحات موضوعية: Heterozygote, Amino Acid Motifs, Blotting, Western, Molecular Sequence Data, education, Biology, Transfection, CREB, medicine.disease_cause, Exon, Acetyltransferases, Coactivator, Tumor Cells, Cultured, Genetics, medicine, Humans, Amino Acid Sequence, CREB-binding protein, Cyclic AMP Response Element-Binding Protein, Molecular Biology, Transcription factor, Genetics (clinical), Chromosome Aberrations, Rubinstein-Taybi Syndrome, Zinc finger, Mutation, Models, Genetic, Sequence Homology, Amino Acid, Reverse Transcriptase Polymerase Chain Reaction, Exons, General Medicine, PHD finger, biology.protein, Plasmids

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd113b15409bb69b30fb004b41dba5ecTest
https://doi.org/10.1093/hmg/ddg039Test

المؤلفون: A. Zantema, Eric Kalkhoven, Hans Teunissen, A. Houweling, C. Peter Verrijzer

المصدر: Molecular and Cellular Biology. 22:1961-1970

مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Transcription, Genetic, Molecular Sequence Data, environment and public health, Cell Line, Conserved sequence, Histones, Acetyltransferases, Transcription (biology), Animals, Humans, Amino Acid Sequence, CREB-binding protein, Cyclic AMP Response Element-Binding Protein, Molecular Biology, Conserved Sequence, Histone Acetyltransferases, Transcriptional Regulation, Genetics, Zinc finger, Sequence Homology, Amino Acid, biology, General transcription factor, Nuclear Proteins, Acetylation, Zinc Fingers, Cell Biology, CREB-Binding Protein, Protein Structure, Tertiary, Histone, PHD finger, Mutation, Trans-Activators, biology.protein, Drosophila

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47deba5c9e5dcc44523152ad797c06b2Test
https://doi.org/10.1128/mcb.22.7.1961-1970.2002Test

المؤلفون: Merlijn Witte, Sabine Middendorp, Hans Teunissen, Hans Clevers, Caroline L. Wiegerinck, Michal Mokry, Edwin Cuppen, Edward E. S. Nieuwenhuis, Claartje A. Meddens

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Gastroenterology, 146(4), 1040-7. W.B. Saunders Ltd

مصطلحات موضوعية: Linkage disequilibrium, Chromatin Immunoprecipitation, Genetically Modified, Genome-wide association study, Single-nucleotide polymorphism, Biology, Regulatory Sequences, Nucleic Acid, Polymorphism, Single Nucleotide, Linkage Disequilibrium, Animals, Genetically Modified, Histones, Risk Factors, Animals, Humans, Genetic Predisposition to Disease, Polymorphism, Intestinal Mucosa, Gene, Immunity, Mucosal, Zebrafish, Genetics, Mucosal, Nucleic Acid, Hepatology, Immunity, Gastroenterology, Reproducibility of Results, Acetylation, Single Nucleotide, DNA, Sequence Analysis, DNA, Inflammatory Bowel Diseases, Intestinal epithelium, Phenotype, Gene Expression Regulation, Regulatory sequence, Genetic Loci, Human genome, Regulatory Sequences, Sequence Analysis, Chromatin immunoprecipitation, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1ae4f917685d974ec45cbc8be83495Test
https://pure.knaw.nl/portal/en/publications/d6a7b375-72e7-4209-82af-e2f07579a8ffTest

المؤلفون: Marjon J.A.M. Verstegen, Hans Teunissen, Eva van den Berg, Wouter de Laat, Max van Min, Petra ter Brugge, Peter H.L. Krijger, Ben Berkhout, Geert Geeven, Marieke F. van Dooren, Elzo de Wit, Paula J P de Vree, Hans Kristian Ploos van Amstel, Bauke Ylstra, Sjef Verbeek, Mohamed Lamkanfi, Ko Willems van Dijk, Petra Klous, Daoud Sie, Mehmet Yilmaz, Lorette O M Hulsman, Rob B. van der Luijt, Erik Splinter, John W. M. Martens, Laura J. C. M. van Zutven, Ans M.W. van den Ouweland, Desiree Weening, Yi Wan, Marjolijn J. L. Ligtenberg, Birgit Sikkema-Raddatz, Magdalena Matusiak, Johan T. den Dunnen, John A. Foekens, Jos Jonkers, Marion Cornelissen, Monique van de Heijning, Paul P. Eijk, Pieter van der Vlies, Atze T. Das

المساهمون: Pathology, CCA - Disease profiling, AII - Amsterdam institute for Infection and Immunity, Medical Microbiology and Infection Prevention, Hubrecht Institute for Developmental Biology and Stem Cell Research, Clinical Genetics, Virology, Cell biology, Otorhinolaryngology and Head and Neck Surgery, Cardiothoracic Surgery, Pulmonary Medicine, Medical Oncology

المصدر: Nature Biotechnology, 32(10), 1019-1025. Nature Publishing Group
Nature biotechnology, 32(10), 1019-1025. Nature Publishing Group
Nature Biotechnology, 32(10), 1019
de Vree, P J P, de Wit, E, Yilmaz, M, de Heijning, M V, Klous, P, Verstegen, M J A M, Wan, Y, Teunissen, H, Krijger, P H L, Geeven, G, Eijk, P P, Sie, D L S, Ylstra, B, Hulsman, L O M, van Dooren, M F, van Zutven, L J C M, van den Ouweland, A, Verbeek, S, van Dijk, K W, Cornelissen, M, Das, A T, Ben, B, Sikkema-Raddatz, B, Berg, E, van der Vlies, P, Weening, D, den Dunnen, J T, Matusiak, M, Lamkanfi, M, Ligtenberg, M J L, ter Brugge, P, Jonkers, J, Foekens, J A, Martens, J W, van der Luijt, R, van Amstel, H K P, van Min, M, Splinter, E & de Laat, W 2014, ' Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping ', Nature Biotechnology, vol. 32, no. 10, pp. 1019-1025 . https://doi.org/10.1038/nbt.2959Test
Nature Biotechnology, 32(10), 1019-25. Nature Publishing Group
Nature Biotechnology, 32, 1019-25
Europe PubMed Central
Nature Biotechnology, 32(10), 1019-+. Nature Publishing Group
Nature Biotechnology, 32(10), 1019-1025.e2. Nature Publishing Group
Nature Biotechnology, 32, 10, pp. 1019-25

مصطلحات موضوعية: EXPRESSION, Sequence analysis, Genes, BRCA2, Genes, BRCA1, Biomedical Engineering, Bioengineering, Locus (genetics), Biology, Polymorphism, Single Nucleotide, Applied Microbiology and Biotechnology, Genome, DNA sequencing, DISEASE, COMPLEX CHROMOSOMAL REARRANGEMENTS, chemistry.chemical_compound, Neoplasms, 4C TECHNOLOGY, Genetic variation, Tumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14], Humans, Gene, Genetics, Models, Genetic, Haplotype, GENETIC-VARIATION, Genomics, Sequence Analysis, DNA, TUMORS, CONFORMATION, GENOME, Haplotypes, chemistry, Genetic Loci, Molecular Medicine, INFLAMMASOME ACTIVATION, Gene Fusion, ENRICHMENT, Nucleic Acid Amplification Techniques, DNA, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babf5e50a5cb3a8d5e9aae208290c03eTest
https://research.vumc.nl/en/publications/cfa6e428-2795-4c22-a92f-57edf9b7d217Test

المؤلفون: Hans Clevers, Pekka Kujala, Shabaz Mohammed, Daniele Guardavaccaro, Marc van de Wetering, Peter J. Peters, Yasuaki Mohri, Albert J. R. Heck, Daniel E. Stange, Richard B.M. Schasfoort, Bon-Kyoung Koo, Vivian S. W. Li, Hans Teunissen, Teck Yew Low, J. van Es, Andrea Haegebarth, Wim de Lau, Katsuhiko Nishimori, Nick Barker

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research, Medical Cell Biophysics, Faculty of Science and Technology

المصدر: Nature, 476(7360), 293-297. Nature Publishing Group

مصطلحات موضوعية: Frizzled, Biology, Receptors, G-Protein-Coupled, Wnt3 Protein, 03 medical and health sciences, Wnt, Mice, 0302 clinical medicine, LGR5, stem cells, Wnt3A Protein, Animals, Humans, Regeneration, RSPO1, RSPO2, Cells, Cultured, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Wnt signaling pathway, LRP6, LRP5, Epithelial Cells, Molecular biology, Frizzled Receptors, Cell biology, Protein Structure, Tertiary, Wnt Proteins, Adult Stem Cells, HEK293 Cells, 030220 oncology & carcinogenesis, Thrombospondins, Gene Deletion, Protein Binding, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5404ec2ebd2e3e08e91b49fafad384d2Test

المؤلفون: Elzo de Wit, Bas Tolhuis, Bas van Steensel, Inhua Muijrers, Hans Teunissen, Wendy Talhout, Maarten van Lohuizen

المصدر: Nature genetics. 38(6)

مصطلحات موضوعية: animal structures, DNA, Complementary, macromolecular substances, Cell Line, Histone H3, Drosophilidae, Genetics, Animals, Drosophila Proteins, Protein Isoforms, Promoter Regions, Genetic, Gene, Polycomb Repressive Complex 1, Genome, biology, Chromatin binding, Gene Expression Profiling, fungi, Polycomb Repressive Complex 2, Histone-Lysine N-Methyltransferase, biology.organism_classification, Chromatin, Drosophila melanogaster, biology.protein, PRC1, PRC2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77d9a4c493f5b1f9ba976e546c187f3Test
https://pubmed.ncbi.nlm.nih.gov/16628213Test