المؤلفون: Guimarães, Aparecida Patricia, Seidel, Helen, de Medeiros Pires, Larissa Vitalina, Trindade, Cristina Oliveira, dos Santos Baleeiro, Raianne, de Souza, Perciliany Martins, Drummond e Silva, Fernanda Guimarães, Coelho, Daniel Barbosa, Becker, Lenice Kappes, de Oliveira, Emerson Cruz

مصطلحات موضوعية: Medicine, Neuroscience, Physiology, FOS Biological sciences, Biotechnology, Chemical Sciences not elsewhere classified, Immunology, FOS Clinical medicine, Science Policy, Mental Health

الوصف: Gamma-aminobutyric acid (GABA) serves as a pivotal neurotransmitter implicated in the pathogenesis of stress, anxiety, sleep-related disorders, and heart rate (HR) reactions. Heart-rate variability (HRV), modulated by the sympathetic and parasympathetic branches of the autonomic nervous system (ANS), offers insights into cardiac autonomic control and cardiovascular well-being. The present study aimed to explore the impact of GABA supplementation on emotional metrics, sleep quality, and HRV in sedentary women with overweight or obesity partaking in physical exercise. A randomized, double-blind, placebo-controlled clinical trial was undertaken involving 30 sedentary women with overweight or obesity. Volunteers were assigned randomly to two groups: the intervention group receiving GABA (200 mg) once daily for a total of 90 supplementation doses, and the placebo group. Both groups engaged in physical exercise, while the supplementation regimen spanned 90 days. Assessments were conducted at three intervals: ...

العلاقة: https://dx.doi.org/10.1080/19390211.2024.2308262Test

الإتاحة: https://doi.org/10.6084/m9.figshare.2515802110.1080/19390211.2024.2308262Test
https://tandf.figshare.com/articles/journal_contribution/GABA_Supplementation_Increased_Heart-Rate_Variability_Emotional_Response_Sleep_Efficiency_and_Reduced_Depression_in_Sedentary_Overweight_Women_Undergoing_Physical_Exercise_Placebo-Controlled_Randomized_Clinical_Trial/25158021Test

المؤلفون: Baleeiro, Raianne dos Santos¹ (AUTHOR), Guimarães, Aparecida Patricia² (AUTHOR), Souza, Perciliany Martins de³ (AUTHOR), Andrade, Rafael da Silva² (AUTHOR), Barbosa de Queiroz, Karina⁴ (AUTHOR), Coelho, Daniel Barbosa² (AUTHOR), Oliveira, Emerson Cruz de² (AUTHOR), Becker, Lenice Kappes² (AUTHOR)

المصدر: Journal of Nutrition & Metabolism. 3/9/2021, p1-10. 10p.

مصطلحات موضوعية: *PHYSICAL mobility, *HEALTH behavior, *SPORTS drinks, *SYSTOLIC blood pressure, *RATE of perceived exertion, *BODY mass index

مستخلص: Introduction. The intake of sugar-sweetened beverages (SSBs) has increased rapidly, but the effects of this habit on health and physical performance are unknown. This study assessed the effect of excessive SSB intake on biochemical, physical performance, and biochemical and cardiovascular parameters of physically active males. Methods. Seventeen volunteers consumed a placebo drink (Pd; carbohydrate free) and an excessive SSB drink (eSSBd = Pd plus 300 g sucrose). In a blind randomized crossover study, the subjects were assigned to Pd or eSSBd groups for 15 days. After an interval of 7 days, subjects were reassigned to the other condition. Results. After eSSBd intake, there was an increase in weight (69.34 ± 13.71 vs. 70.62 ± 14.06), body mass index (24.49 ± 4.01 vs. 24.97 ± 4.13), waist circumference (75.33 ± 11.22 vs. 76.79 ± 11.51), VLDL (19.54 ± 9.50 vs. 25.52 ± 11.18), triglycerides (78.94 ± 23.79 vs. 114.77 ± 43.65), and peak systolic blood pressure (178.57 ± 26.56 vs. 200.71 ± 24.64). The cardiorespiratory response to exercise (VO2max) (48.15 ± 10.42 vs. 40.98 ± 11.20), peak heart rate (186.64 ± 8.00 vs. 179.64 ± 6.28), total exercise time (15.02 ± 1.57 vs. 14.00 ± 2.18), and mechanical work (15.83 ± 4.53 vs. 13.68 ± 5.67) decreased after eSSBd intake (all values expressed in initial mean ± DP vs. final). The rates of perceived exertion were higher (1.300 vs.1.661 slope and −0.7186 vs. −1.118 y-intercept) after eSSBd intake. Conclusion. The present study shows that 15 days of eSSBd intake may negatively modulate biochemical parameters associated with cardiovascular risk. In addition, this overintake can impair the physical performance and cardiovascular responses to physical exercise. [ABSTRACT FROM AUTHOR]