المؤلفون: Gavaud, Solenn, Perrier, Cyrielle, Nalovic, Alexis, Lion, Julie, Jahoui, Anissa, Marchand, Dominique, Belloc, Catherine, Lieubeau, Blandine, Hervé, Julie, Muller, Vincent, Werner, Laurent, Tatone, Fabrizio

المساهمون: Immuno-Endocrinologie Cellulaire et Moléculaire (IECM), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Selas Epidalis Vitré, Biologie, Epidémiologie et analyse de risque en Santé Animale (BIOEPAR), IFIP, INRAE

المصدر: 56. journées de la Recherche Porcine
https://hal.inrae.fr/hal-04472981Test
56. journées de la Recherche Porcine, IFIP
INRAE, Feb 2024, Saint-Malo, France. pp.283-288
https://www.journees-recherche-porcine.com/texte/2024.phpTest

مصطلحات موضوعية: [SDV]Life Sciences [q-bio]

جغرافية الموضوع: Saint-Malo, France

الوصف: International audience ; Citizens are currently raising concerns about conventional breeding systems including their environmental impacts and respect for animal welfare. Identifying realistic solutions that are easily transferable to the field and that improve animal health and welfare is a major challenge. Socialisation in the nursery appears to be a relevant mechanism for improving the health and welfare of pigs. In this context, we compared the welfare, growth and health of pigs reared with and without socialisation from 14 days of age (D14) on four commercial farms. Early socialisation did not influence the health or growth of pigs. Immediately after mixing at 14 days of age, the socialised group exhibited more exploratory behaviours than the control group (14.6 vs 3.2%, P < 0.001), with more frequent positive social interactions (5.0 vs 1.9%, P < 0.01). At weaning, pre-socialised piglets had significantly lower salivary cortisol concentrations than control piglets did (10.6 vs 13.8 ng/ml, P < 0.05) and exhibited more positive social behaviours (10.0 vs 2.9%, P<0.001). Overall, the severity of body lesions in socialised piglets was significantly lower than in control piglets (P<0.05). Finally, although the sows were less calm when their litters were mixed, the proportion of sows with lesions on udders was not different in both groups. Early socialisation therefore appears to be a possible path forward for improving the welfare of piglets, but questions remain such as those relating to the welfare of the sows and the working conditions of pig farmers ; De nos jours, le système d’élevage conventionnel de porcs en bâtiment, est questionné par les citoyens, tant sur son empreinte environnementale que sur le respect du bien-être animal. Identifier des solutions facilement transposables sur le terrain, qui améliorent la santé et le bien-être des animaux, constitue un enjeu majeur. Ainsi, la socialisation en maternité apparaît comme un levier pertinent pour répondre à ces objectifs. Le retrait des ...

العلاقة: hal-04472981; https://hal.inrae.fr/hal-04472981Test; https://hal.inrae.fr/hal-04472981/documentTest; https://hal.inrae.fr/hal-04472981/fileTest/Gavaud%20Perrier%20JRP%202024-189-B10.pdf

الإتاحة: https://hal.inrae.fr/hal-04472981Test
https://hal.inrae.fr/hal-04472981/documentTest
https://hal.inrae.fr/hal-04472981/fileTest/Gavaud%20Perrier%20JRP%202024-189-B10.pdf

المؤلفون: Pierre Levallois, Mily Leblanc-Maridor, Anne Lehébel, Solenn Gavaud, Blandine Lieubeau, Julie Hervé, Christine Fourichon, Catherine Belloc

المصدر: Frontiers in Veterinary Science, Vol 10 (2024)

مصطلحات موضوعية: hair cortisol, stress, biomarker, pig, welfare, health, Veterinary medicine, SF600-1100

الوصف: Hair cortisol is a stress indicator and could be used to assess the pigs’ exposure to stressors in the weeks/months prior to non-invasive hair sampling. The main aim of this study was to describe the hair cortisol concentration (HCC) variability between individuals within a batch, between farms and between batches within a farm. The secondary aim was to determine how the number of sampled pigs influences the characterization of HCC within a batch. Twenty farrow-to-finish pig farms were recruited considering the diversity of their management practices and health status (data collected). Hair was sampled in two separate batches, 8 months apart. The necks of 24 finishing pigs were clipped per batch the week prior to slaughter. To describe the variability in HCC, an analysis of the variance model was run with three explanatory variables (batch, farm and their interaction). To identify farm clusters, a principal component analysis followed by a hierarchical clustering was carried out with four active variables (means and standard deviations of the two batches per farm) and 17 supplementary variables (management practices, herd health data). We determined how the number of sampled pigs influenced the characterization of HCC within a batch by selecting subsamples of the results. HCC ranged from 0.4 to 121.6 pg/mg, with a mean of 25.9 ± 16.2 pg/mg. The variability in HCC was mainly explained by differences between pigs (57%), then between farms (24%), between batches within the same farm (16%) and between batches (3%). Three clusters of farms were identified: low homogeneous concentrations (n = 3 farms), heterogeneous concentrations with either higher (n = 7) or lower (n = 10) HCC in batch 2 than in batch 1. The diversity of management practices and health statuses allowed to discuss hypotheses explaining the HCC variations observed. We highlighted the need to sample more than 24 pigs to characterize HCC in a pig batch. HCC differences between batches on six farms suggest sampling pigs in more than one batch to describe the HCC at the farm level. HCC variations described here confirm the need to study its links with exposure of pigs to stressors.

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fvets.2023.1298756/fullTest; https://doaj.org/toc/2297-1769Test

الوصول الحر: https://doaj.org/article/b9cfa6b0449d4d0dab0243362de47e5eTest

المؤلفون: Levallois, Pierre, Leblanc-Maridor, Mily, Lehébel, Anne, Gavaud, Solenn, Lieubeau, Blandine, Hervé, Julie, Fourichon, Christine, Belloc, Catherine

المساهمون: Biologie, Epidémiologie et analyse de risque en Santé Animale (BIOEPAR), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Immuno-Endocrinologie Cellulaire et Moléculaire (IECM), The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This study was co-funded by the EU part of the HealthyLivestock project, funded by the EU Horizon 2020 Research and Innovation Program under grant agreement number 773436 and the Région Pays de la Loire (number of contract 2020_10347)

المصدر: ISSN: 2297-1769 ; Frontiers in Veterinary Science ; https://oniris.hal.science/hal-04410821Test ; Frontiers in Veterinary Science, 2024, 10, pp.1298756. ⟨10.3389/fvets.2023.1298756⟩ ; https://www.frontiersin.org/articles/10.3389/fvets.2023.1298756/fullTest.

مصطلحات موضوعية: Hair cortisol, Stress, Biomarker, Pig, Welfare, Health, Field study, [SDV]Life Sciences [q-bio]

الوصف: International audience ; Hair cortisol is a stress indicator and could be used to assess the pigs’ exposure to stressors in the weeks/months prior to non-invasive hair sampling. The main aim of this study was to describe the hair cortisol concentration (HCC) variability between individuals within a batch, between farms and between batches within a farm. The secondary aim was to determine how the number of sampled pigs influences the characterization of HCC within a batch. Twenty farrow-to-finish pig farms were recruited considering the diversity of their management practices and health status (data collected). Hair was sampled in two separate batches, 8 months apart. The necks of 24 finishing pigs were clipped per batch the week prior to slaughter. To describe the variability in HCC, an analysis of the variance model was run with three explanatory variables (batch, farm and their interaction). To identify farm clusters, a principal component analysis followed by a hierarchical clustering was carried out with four active variables (means and standard deviations of the two batches per farm) and 17 supplementary variables (management practices, herd health data). We determined how the number of sampled pigs influenced the characterization of HCC within a batch by selecting subsamples of the results. HCC ranged from 0.4 to 121.6 pg/mg, with a mean of 25.9 ± 16.2 pg/mg. The variability in HCC was mainly explained by differences between pigs (57%), then between farms (24%), between batches within the same farm (16%) and between batches (3%). Three clusters of farms were identified: low homogeneous concentrations (n = 3 farms), heterogeneous concentrations with either higher (n = 7) or lower (n = 10) HCC in batch 2 than in batch 1. The diversity of management practices and health statuses allowed to discuss hypotheses explaining the HCC variations observed. We highlighted the need to sample more than 24 pigs to characterize HCC in a pig batch. HCC differences between batches on six farms suggest sampling pigs in more ...

العلاقة: hal-04410821; https://oniris.hal.science/hal-04410821Test; https://oniris.hal.science/hal-04410821/documentTest; https://oniris.hal.science/hal-04410821/file/Levallois%20et%20al-2024.pdfTest; WOS: 001156139900001

الإتاحة: https://doi.org/10.3389/fvets.2023.129875610.3389/fvets.2023.1298756/fullTest
https://oniris.hal.science/hal-04410821Test
https://oniris.hal.science/hal-04410821/documentTest
https://oniris.hal.science/hal-04410821/file/Levallois%20et%20al-2024.pdfTest

المؤلفون: Moutel, Marin, Peju, Edwidge, Belan, Martin, Gavaud, Ariane, Mira, Jean-Paul, Charlier, Caroline, Canouï, Etienne, Gastli, Nabil

المصدر: Infectious Diseases Now ; volume 54, issue 5, page 104892 ; ISSN 2666-9919

مصطلحات موضوعية: Infectious Diseases

الإتاحة: https://doi.org/10.1016/j.idnow.2024.104892Test
https://api.elsevier.com/content/article/PII:S2666991924000472?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2666991924000472?httpAccept=text/plainTest

المؤلفون: Julie Hervé, Karine Haurogné, Arnaud Buchet, Elodie Bacou, Grégoire Mignot, Marie Allard, Mily Leblanc-Maridor, Solenn Gavaud, Anne Lehébel, Elena Terenina, Pierre Mormède, Elodie Merlot, Catherine Belloc, Jean-Marie Bach, Blandine Lieubeau

المصدر: BMC Immunology, Vol 23, Iss 1, Pp 1-12 (2022)

مصطلحات موضوعية: Immunity, Pig, Pathogen exposure, Weaning, On-field study, Immunologic diseases. Allergy, RC581-607

الوصف: Abstract Background Multiple antigenic stimulations are crucial to immune system training during early post-natal life. These stimulations can be either due to commensals, which accounts for the acquisition and maintenance of tolerance, or to pathogens, which triggers immunity. In pig, only few works previously explored the influence of natural exposition to pathogens upon immune competence. We propose herein the results of a multicentric, field study, conducted on 265 piglets exposed to contrasted pathogen levels in their living environment. Piglets were housed in 15 different commercial farms, sorted in two groups, low (HSLOW)- and high (HSHIGH)-health status farms, depending on their recurrent exposition to five common swine pathogens. Results Using animal-based measures, we compared the immune competence and growth performances of HSLOW and HSHIGH pigs around weaning. As expected, we observed a rise in the number of circulating leucocytes with age, which affected different cell populations. Monocyte, antigen-experienced and cytotoxic lymphocyte subpopulation counts were higher in piglets reared in HSLOW farms as compared to their HSHIGH homologs. Also, the age-dependent evolution in γδ T cell and neutrophil counts was significantly affected by the health status. With age, circulating IFNα level decreased and IgM level increased while being greater in HSLOW piglets at any time. After weaning, LPS-stimulated blood cells derived from HSLOW piglets were more prone to secrete IL-8 than those derived from HSHIGH pigs did. Monocytes and granulocytes issued from HSLOW pigs also exhibited comparable phagocytosis capacity. Altogether our data emphasize the more robust immunophenotype of HSLOW piglets. Finally, piglets raised under higher pathogen pressure grew less than HSHIGH piglets did and exhibited a different metabolic profile. The higher cost of the immune responses associated with the low farm health status may account for lower HSLOW piglet performances. Conclusions Altogether, our data, obtained in field conditions, provide evidence that early exposure to pathogens shapes the immune competence of piglets. They also document the negative impact of an overstimulation of the immune system on piglets’ growth.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1471-2172Test

الوصول الحر: https://doaj.org/article/1c762acaf2984dae84bfd6856b771a5cTest

المؤلفون: S. Gavaud, K. Haurogné, A. Buchet, I. Garcia Vinado, M. Allard, A. Lehébel, M. Leblanc-Maridor, J.M. Bach, C. Belloc, B. Lieubeau, J. Hervé

المصدر: Animal, Vol 17, Iss 6, Pp 100810- (2023)

مصطلحات موضوعية: Body lesions, Early socialisation, Growth, Immune competence, Stress, Animal culture, SF1-1100

الوصف: Nowadays, most pigs are raised indoors, on intensive farms providing a poor environment. In these conditions, the risk of the occurrence of damaging behaviours is high, with dramatic consequences for animal health and welfare as well as economic losses for farmers. Early-life conditions may predispose individuals to develop damaging behaviours later in life. In contrast, reinforcing affiliative behaviours between piglets before weaning might help to prevent tail-biting episodes. In this field study, we aimed at improving early-life conditions of piglets on a commercial farm by completely suppressing painful procedures and staggering their exposure to weaning stress factors. The alternative early-life management strategy combined housing in free-farrowing pens with temporary crating of the sow, socialisation during the lactation period with whole-life maintenance of the hierarchical groups, and delayed transfer to the postweaning room after sow removal. Control conditions included birth in farrowing crates, tail docking, absence of socialisation during the lactation period, abrupt weaning with immediate transfer to the postweaning room and mixing with non-littermates. We evaluated the health, welfare, and performance of alternatively raised pigs (n = 80) as compared to controls (n = 75). Visits were made throughout the lifespan of individuals to evaluate their growth and health status. Body and tail lesions were scored as proxy measures of aggressiveness and impaired welfare. Blood and bristle samples were periodically collected to evaluate stress, inflammation and immune competence. While the whole-life performance of pigs was similar among groups, the alternative early-life conditions prevented the growth slowdown usually observed after weaning. In addition, alternatively raised pigs displayed more neutrophils, eosinophils and monocytes the day after weaning, as well as higher C-Reactive Protein levels. One week later, their monocytes displayed greater phagocytic capacity. Altogether, these data suggest an enhanced innate immune competence for alternatively raised pigs around weaning. Piglets reared under alternative conditions also exhibited fewer and less severe body lesions than standard pigs, one week after weaning. In contrast, they showed more tail lesions on days 36 and 66 associated with greater levels of acute phase proteins (C-Reactive Protein and haptoglobin). To conclude, alternative early-life management better prepared piglets for weaning. However, the whole-life maintenance of early-established social groups was not sufficient to prevent the occurrence of damaging behaviours in undocked pigs.

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S1751731123001064Test; https://doaj.org/toc/1751-7311Test

الوصول الحر: https://doaj.org/article/89180d3329554276a76c4e88ddc890a5Test

المؤلفون: Levallois, Pierre, Leblanc-Maridor, Mily, Gavaud, Solenn, Lieubeau, Blandine, Morgant, Guillaume, Fourichon, Christine, Hervé, Julie, Belloc, Catherine

المساهمون: Biologie, Epidémiologie et analyse de risque en Santé Animale (BIOEPAR), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS), Immuno-Endocrinologie Cellulaire et Moléculaire (IECM), Métaprogramme SANBA, IFIP, INRAE

المصدر: 55èmes Journées de la Recherche Porcine
https://hal.inrae.fr/hal-04351072Test
55èmes Journées de la Recherche Porcine, IFIP
INRAE, Jan 2023, Saint Malo, France. pp.63-68
https://www.journees-recherche-porcine.comTest/

مصطلحات موضوعية: [SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health

جغرافية الموضوع: Saint Malo, France

الوصف: International audience ; Cortisol accumulates in hair over time. Measuring hair cortisol could thus be used to assess the exposure of pigs to stress in the weeks/months prior to sampling. The objective of this study was to describe the variability in hair cortisol concentrations within a batch, between batches and among farms in twenty farrow-to-finish farms in western France, selected according to the diversity of their management practices and their health status. Hair was sampled twice on the farms, eight months apart. The necks of 24 fattening pigs were clipped during each sampling session. The management practices and health status of the farms were also described. To describe the variability in hair cortisol concentrations, a linear model was built, and hierarchical clustering on principal components was performed. Hair cortisol concentration ranged from 0,4 to 121,6 pg/mg, with a mean of 25,9 ± 16,2 pg/mg. Within a batch, the coefficient of variation of hair cortisol concentration ranged from 15 and 71 %. On six farms, hair cortisol concentration differed significantly between the two batches sampled. Hair cortisol concentration varied significantly among farms and three farm clusters were identified: low and homogeneous concentration (n = 3 farms) or higher and heterogeneous concentration for the first (n = 9) or second (n = 8) batch sampled. The management practices and health statuses allowed us to consider explanatory hypotheses for the observed variations. Thus, pig hair, whose collection is not invasive, may be relevant for studying stress exposure on pig farms ; Le cortisol s’accumule au cours du temps dans les soies. Le dosage du cortisol pilaire pourrait permettre d’évaluer l’exposition des porcs au stress durant les semaines/mois précédant le prélèvement. L’objectif de cette étude est de décrire les variabilités des concentrations de cortisol pilaire intra-bande, inter-bandes et inter-élevages dans 20 élevages naisseurs-engraisseurs du grand-ouest français, sélectionnés en considérant la ...

العلاقة: hal-04351072; https://hal.inrae.fr/hal-04351072Test; https://hal.inrae.fr/hal-04351072/documentTest; https://hal.inrae.fr/hal-04351072/file/Levallois2023JRP.pdfTest

الإتاحة: https://hal.inrae.fr/hal-04351072Test
https://hal.inrae.fr/hal-04351072/documentTest
https://hal.inrae.fr/hal-04351072/file/Levallois2023JRP.pdfTest

المؤلفون: Palich, Romain, Burrel, Sonia, Monsel, Gentiane, Nouchi, Agathe, Bleibtreu, Alexandre, Seang, Sophie, Bérot, Vincent, Brin, Cécile, Gavaud, Ariane, Wakim, Yara, Godefroy, Nagisa, Fayçal, Antoine, Tamzali, Yanis, Grunemwald, Thomas, Ohayon, Michel, Todesco, Eve, Leducq, Valentin, Marot, Stéphane, Calvez, Vincent, Marcelin, Anne-Geneviève, Pourcher, Valérie

المساهمون: CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Centre Hospitalier Andrée Rosemon Cayenne, Guyane Française, Maladies métaboliques, diabète et co-morbidités = Metabolic Diseases, Diabetes and co-morbidities CRC, Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), CHU Tenon AP-HP, Centre de santé sexuelle

المصدر: ISSN: 1473-3099.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio]

الوصف: International audience ; Background: Monkeypox virus (MPXV) is currently spreading among men who have sex with men, outside of sub-Saharan Africa, and close contact during sex seems to be one of the key pathways of viral transmission in the current outbreak. Our aim was to describe the distribution of MPXV in the human body, as it might play a role in its dissemination through sexual contact.Methods: The study population in this case series consisted of patients with confirmed MPXV infection attending the Pitié-Salpêtrière Hospital (Paris, France), who had been sampled from multiple anatomical sites, including skin, anus, throat, blood, urine, and semen, at diagnosis and 2 weeks later. We compared the proportion of positive samples and MPXV viral loads (given as PCR cycle thresholds [Ct]) between anatomical sites, and between day 0 (D0) and D14.Findings: Overall, 356 samples were collected between May 20 and June 13, 2022, from 50 men with a median age of 34 years (IQR 29-40). 22 (44%) of the 50 men were classified as HIV-negative on day (D)0, and 22 (44%) were living with HIV. At D0, MPXV detection was more frequent from skin (44 [88%] of 50), anus (30 [71%] of 42), and throat (36 [77%] of 47) than from blood (13 [29%] of 45), urine (nine [22%] of 41), or semen (13 [54%] of 24). Viral loads were significantly higher from skin lesions (Ct 19·8) and anal samples (Ct 20·9) than from throat (Ct 27·2), blood (Ct 32·8), urine (31·1), or semen samples (Ct 27·8). When analysing the 107 samples taken from 24 patients at D14, the proportion of positive samples strongly decreased between D0 and D14 at all sites: skin (four [22%] of 18), anus (two [9%] of 22), throat (none of 21), blood (one [5%] of 21), urine (none of 14), and semen (two [9%] of 11).Interpretation: These data contribute to a better understanding of how the virus might spread between sexual partners over a relatively short period of time. High MPXV viral loads from skin and mucosa, including genital and anal sites, suggest that transmission most likely ...

العلاقة: hal-03939118; https://hal.science/hal-03939118Test; https://hal.science/hal-03939118/documentTest; https://hal.science/hal-03939118/file/VL%20Lancet%20ID.pdfTest

الإتاحة: https://doi.org/10.1016/s1473-3099Test(22)00586-2
https://hal.science/hal-03939118Test
https://hal.science/hal-03939118/documentTest
https://hal.science/hal-03939118/file/VL%20Lancet%20ID.pdfTest

المؤلفون: Gavaud, S., Haurogné, K., Buchet, A., Garcia Vinado, I., Allard, M., Lehébel, A., Leblanc-Maridor, M., Bach, J.M., Belloc, C., Lieubeau, B., Hervé, J.

المساهمون: Immuno-Endocrinologie Cellulaire et Moléculaire (IECM), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), COOPERL INNOVATION S.A.S, Hyovet, Biologie, Epidémiologie et analyse de risque en Santé Animale (BIOEPAR), This work was supported by the Association LIT Ouesterel and the French government through the ‘‘Programme d’Investissement d’Avenir (action: Territoires d’Innovation de grande ambition, Op3.10)”. Cooperl Innovation supported extra costs on the farm.

المصدر: ISSN: 1751-7311.

مصطلحات موضوعية: Body lesions, Early socialisation, Growth, Immune competence, Stress, [SDV]Life Sciences [q-bio]

الوصف: International audience ; Nowadays, most pigs are raised indoors, on intensive farms providing a poor environment. In these conditions, the risk of the occurrence of damaging behaviours is high, with dramatic consequences for animal health and welfare as well as economic losses for farmers. Early-life conditions may predispose individuals to develop damaging behaviours later in life. In contrast, reinforcing affiliative behaviours between piglets before weaning might help to prevent tail-biting episodes. In this field study, we aimed at improving early-life conditions of piglets on a commercial farm by completely suppressing painful procedures and staggering their exposure to weaning stress factors. The alternative early-life management strategy combined housing in free-farrowing pens with temporary crating of the sow, socialisation during the lactation period with whole-life maintenance of the hierarchical groups, and delayed transfer to the postweaning room after sow removal. Control conditions included birth in farrowing crates, tail docking, absence of socialisation during the lactation period, abrupt weaning with immediate transfer to the postweaning room and mixing with non-littermates. We evaluated the health, welfare, and performance of alternatively raised pigs (n = 80) as compared to controls (n = 75). Visits were made throughout the lifespan of individuals to evaluate their growth and health status. Body and tail lesions were scored as proxy measures of aggressiveness and impaired welfare. Blood and bristle samples were periodically collected to evaluate stress, inflammation and immune competence. While the whole-life performance of pigs was similar among groups, the alternative early-life conditions prevented the growth slowdown usually observed after weaning. In addition, alternatively raised pigs displayed more neutrophils, eosinophils and monocytes the day after weaning, as well as higher C-Reactive Protein levels. One week later, their monocytes displayed greater phagocytic capacity. Altogether, ...

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37172358; hal-04107212; https://hal.inrae.fr/hal-04107212Test; https://hal.inrae.fr/hal-04107212/documentTest; https://hal.inrae.fr/hal-04107212/file/1-s2.0-S1751731123001064-main-1.pdfTest; PUBMED: 37172358; WOS: 001025540200001

الإتاحة: https://doi.org/10.1016/j.animal.2023.100810Test
https://hal.inrae.fr/hal-04107212Test
https://hal.inrae.fr/hal-04107212/documentTest
https://hal.inrae.fr/hal-04107212/file/1-s2.0-S1751731123001064-main-1.pdfTest

المؤلفون: Gavaud, Solenn, Haurogne, Karine, Buchet, Arnaud, Garcia-Vinado, Inès, Allard, Marie, Leblanc-Maridor, Mily, Bach, Jean-Marie, Belloc, Catherine, Lieubeau, Blandine, Hervé, Julie

المساهمون: Immuno-Endocrinologie Cellulaire et Moléculaire (IECM), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Cooperl Arcatlantique, Hyovet, Biologie, Epidémiologie et analyse de risque en Santé Animale (BIOEPAR), Ifip, INRAE

المصدر: Journées de la Recherche Porcine ; 54. Journées de la Recherche Porcine ; https://hal.inrae.fr/hal-03671395Test ; 54. Journées de la Recherche Porcine, Ifip; INRAE, Feb 2022, Paris, France. pp.281-286 ; http://www.journees-recherche-porcine.com/texte/2022.phpTest

مصطلحات موضوعية: Welfare --- porc, Animal health, Weaned piglet, Pig breeding, Santé animale, Bien-être animal, Porcelet sevré, Elevage porcin, [SDV]Life Sciences [q-bio]

جغرافية الموضوع: Paris, France

الوصف: International audience ; In France, the majority of pigs is raised on full-slatted floors and exposed to many stress factors, especially at weaning. The aim of the WellPigWean project consists in analyzing, in a conventional commercial farm, on a hundred pigs, the consequences of an alternative breeding strategy (birth in free-farrowing pen, no tail docking, socialization of piglets from the age of 9 days and maintenance of established social groups until slaughter) in relation to standard breeding conditions. For this purpose, stress, immune competence, behavior and performances of animals were assessed from the age of 10 days until slaughter.Just after weaning, the pre-socialized piglets in the free-farrowing pen show significantly less body lesions than their counterparts reared under standard conditions. At the same age, their numbers of circulating leukocytes are higher than those of non-presocialized pigs. Unfortunately, the occurrence, during post-weaning, of tail-biting episodes induced a significant and lasting increase in tail lesions in individuals raised under alternative breeding strategy. Despite rapid and appropriate management, this was accompanied by an increase in serum levels of C-reactive protein and an increase in the concentration of hair cortisol, indicating an alteration in animal welfare. On the other hand, as it was a field-test it was difficult to control whole parameters, and pigs raised under alternative conditions were significantly younger than their counterparts, which may explain, at least partly, their lower levels of anti-PCV2 antibodies after vaccination. Despite this, the overall performances (weight, ADG, P1, Tmp) of pigs from both groups are similar ; En France, la majorité des porcs est élevée sur caillebotis et exposée à de nombreux facteurs de stress, en particulier lors du sevrage. L’objectif du projet WellPigWean consiste à analyser, dans un élevage commercial conventionnel, sur une centaine de porcs charcutiers, les conséquences d’une conduite d’élevage alternative ...

العلاقة: hal-03671395; https://hal.inrae.fr/hal-03671395Test; https://hal.inrae.fr/hal-03671395/documentTest; https://hal.inrae.fr/hal-03671395/file/b05.pdfTest

الإتاحة: https://hal.inrae.fr/hal-03671395Test
https://hal.inrae.fr/hal-03671395/documentTest
https://hal.inrae.fr/hal-03671395/file/b05.pdfTest