المؤلفون: Al-Hawary, Sulieman Ibraheem Shelash, Mushabab, Faris, Abullais, Shahabe Saquib, Althomali, Raed H., Saleh, Ebraheem Abdu Musad, Alnajjar, Serar Nassir, Oudaha, Khulood H., Romero-Parra, Rosario Mireya, Hussien, Beneen M., Garousi, Nazila

المصدر: Frontiers in Nutrition ; volume 10 ; ISSN 2296-861X

مصطلحات موضوعية: Nutrition and Dietetics, Endocrinology, Diabetes and Metabolism, Food Science

الوصف: Background and aim Several studies have identified that dietary acid load (DAL) may be associated with the odds of metabolic syndrome (MetS); however, the evidence is inconclusive. This dose–response meta-analysis aimed to examine the relation of DAL to MetS. Methods A systematic literature search was carried out in PubMed and Scopus up to April 2023 for pertinent studies evaluating the relation of DAL scores, including potential renal acid load (PRAL) and net endogenous acid production (NEAP), to the odds of MetS. The odds ratios (OR) with 95% confidence intervals (CI) were pooled using a random-effects meta-analysis to test the association. Results Eight studies, with an overall sample size of 31,351 participants, were included in this meta-analysis. Higher DAL scores were significantly related to the elevated odds of MetS (NEAP: OR = 1.42, 95%CI = 1.12–1.79; PRAL: OR = 1.76, 95%CI = 1.11–2.78), with significant evidence of heterogeneity across studies. The linear dose–response analysis proposed that a 10 mEq/day elevation in NEAP and PRAL was linked to a 2% (OR = 1.02, 95%CI = 1.001–1.05) and 28% (OR = 1.28, 95%CI = 1.11–1.47) increased odds of MetS, respectively. No non-linear association was observed between MetS and NEAP (P-non-linearity = 0.75) and PRAL (P-non-linearity = 0.92). Conclusion This study revealed a significant direct relationship between DAL and MetS. Therefore, lower acidogenic diets are suggested for the prevention of MetS.

الإتاحة: https://doi.org/10.3389/fnut.2023.1233746Test

المؤلفون: Margiana, Ria, Hamoud Alshahrani, Shadia, Kayumova, Dilrabo, Hussien Radie Alawadi, Ahmed, Hjazi, Ahmed, Alsalamy, Ali, Qasim, Qutaiba A., Juyal, Ashima, Garousi, Nazila

المصدر: International Journal of Environmental Health Research; Aug2024, Vol. 34 Issue 8, p2947-2956, 10p

مصطلحات موضوعية: DRINKING (Physiology), RISK assessment, STATISTICAL models, MATERNAL exposure, PREMATURE infants, META-analysis, SYSTEMATIC reviews, MEDLINE, ODDS ratio, WATER, ARSENIC, ONLINE information services, CONFIDENCE intervals, DATA analysis software, REGRESSION analysis, PREGNANCY

مستخلص: The relation of exposure to arsenic in drinking water during pregnancy to the risk of preterm birth (PTB) was contradictory. This meta-analysis aimed to examine the association between drinking water arsenic and PTB. A systematic search in PubMed and Scopus was performed to achieve all relevant studies. Odds ratios (OR) and 95% confidence intervals (CI) were used to pool data using the random-effect models. Overall, 11 studies with a total sample size of 3,404,189 participants were included in the meta-analysis. Arsenic exposure through drinking water during pregnancy was related to an increased risk of PTB (OR = 1.06; 95%CI = 1.01–1.10 for highest versus lowest category of arsenic), with significant heterogeneity across the studies (I² = 84.8%, P = 0.001). This finding was supported by cohort studies (OR = 1.05; 95%CI = 1.01–1.10). This meta-analysis proposes that higher arsenic exposure in drinking water may be a risk factor for PTB. [ABSTRACT FROM AUTHOR]

: Copyright of International Journal of Environmental Health Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Ramaiah, Pushpamala, Baljon, Kamilya Jamel, Hjazi, Ahmed, Qasim, Maytham T., Salih Al-ani, Omar Abdulwahid, Imad, Shad, Hussien, Beneen M., Alsalamy, Ali, Garousi, Nazila

المصدر: BMC Endocrine Disorders; 3/1/2024, Vol. 24 Issue 1, p1-14, 14p

مصطلحات موضوعية: METABOLIC syndrome risk factors, ONLINE information services, POLYPHENOLS, META-analysis, FLAVONOIDS, FOOD consumption, SYSTEMATIC reviews, ISOFLAVONES, RISK assessment, STILBENE, QUERCETIN, FLAVONES, MEDLINE, FLAVANONES

مستخلص: Background: Accumulating evidence has suggested that dietary polyphenols may be protective against metabolic syndrome (MetS); however, the available evidence is contradictory. The aim of this meta-analysis was to assess the association between dietary intake of polyphenols and the odds of MetS. Methods: The PubMed and Scopus databases were systematically searched to obtain eligible studies. The risk of MetS for the highest versus the lowest intakes of total, subclasses and individual polyphenols were examined by pooling odds ratios (OR) and 95% confidence intervals (95%CI) using the random effects model. Results: A total of 14 studies (6 cohort and 8 cross-sectional studies) involving a total of 50,366 participants with 10,879 cases of MetS were included. When various polyphenol compounds were pooled, they were significantly related to a 22% decreased odds of MetS (([5 studies]; OR: 0.78; 95%CI: 0.72–0.85). Higher intakes of total flavonoids (([9 studies]; OR: 0.78; 95%CI: 0.72–0.85), flavan-3-ols (([2 studies]; OR: 0.64; 95%CI: 0.43–0.94), isoflavones (([3 studies]; OR: 0.84; 95%CI: 0.75–0.93), stilbenes (([4 studies]; OR: 0.86; 95%CI: 0.76–0.97), flavones (([2 studies]; OR: 0.79; 95%CI: 0.71–0.89), and quercetin (([2 studies]; OR: 0.63; 95%CI: 0.43–0.93) were also significantly associated with a decreased risk of MetS. The associations were not modified by the age of the participants. No association was found for total polyphenols, phenolic acids, lignans, anthocyanins, and flavonols. Conclusion: The results of this meta-analysis supported that higher polyphenol intake can lower the risk of MetS. [ABSTRACT FROM AUTHOR]

: Copyright of BMC Endocrine Disorders is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Goodarzi, Golnoosh, Mozaffari, Hadis, Raeisi, Tahereh, Mehravar, Fatemeh, Razi, Bahman, Ghazi, Maryam Lafzi, Garousi, Nazila, Alizadeh, Shahab, Janmohammadi, Parisa

المصدر: BMC Cancer ; volume 22, issue 1 ; ISSN 1471-2407

مصطلحات موضوعية: Cancer Research, Genetics, Oncology

الوصف: Background The association of obesity with colorectal cancer (CRC) may vary depending on metabolic status. Objective This meta-analysis aimed to investigate the combined impacts of obesity and metabolic status on CRC risk. Methods The Scopus, PubMed, and web of sciences databases were systematically searched up to Jun 2021 to find all eligible publications examining CRC risk in individuals with metabolically unhealthy normal-weight (MUHNW), metabolically healthy obesity (MHO), and metabolically unhealthy obesity (MUHO) phenotypes. Results A total of 7 cohort studies with a total of 759,066 participants were included in this meta-analysis. Compared with healthy normal-weight people, MUHNW, MHO, and MUHO individuals indicated an increased risk for CRC with a pooled odds ratio of 1.19 (95% CI = 1.09–1.31) in MUHNW, 1.14 (95% CI = 1.06–1.22) in MHO, and 1.24 (95% CI = 1.19–1.29) in MUHO subjects. When analyses were stratified based on gender, associations remained significant for males. However, the elevated risk of CRC associated with MHO and MUHO was not significant in female participants. Conclusions The individuals with metabolic abnormality, although at a normal weight, have an increased risk for CRC. Moreover, obesity is associated with CRC irrespective of metabolic status.

الإتاحة: https://doi.org/10.1186/s12885-021-09149-wTest

المؤلفون: Garousi, Nazila¹ (AUTHOR), Tamizifar, Babak² (AUTHOR), Pourmasoumi, Makan³ (AUTHOR), Feizi, Awat⁴ (AUTHOR), Askari, Gholamreza⁵ (AUTHOR), Clark, Cain C. T.⁶ (AUTHOR), Entezari, Mohammad Hasan¹ (AUTHOR)

المصدر: Archives of Physiology & Biochemistry. Dec2023, Vol. 129 Issue 4, p975-983. 9p.

مصطلحات موضوعية: *NON-alcoholic fatty liver disease, *INSULIN aspart, *LDL cholesterol, *FISH eggs, *CLINICAL trials, *SYSTOLIC blood pressure, *LOW-fat diet, *DIET

مستخلص: The aim of the study was to compare the effects of a lacto-ovo-vegetarian diet (LOV-D) vs. a standard weight-loss diet (SWL-D) on obese/overweight adults with NAFLD. Present randomised clinical trial recruited 75 overweight/obese adults with NAFLD, who were randomly assigned into LOV-D and SWL-D groups for 3 months. The LOV-D was designed based on eliminating meat, poultry, and fish; while including dairy products and eggs. The SWL-D was planned according to the standard food pyramid, which was free in all sources of food. Adherence to LOV-D significantly outperformed SWL-D in reducing levels of alanine aminotransferase (ALT), body weight, waist circumference, BMI, fasting blood sugar, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), triacylglycerol (TG), cholesterol, low-density lipoprotein cholesterol (LDL-C), and systolic blood pressure (SBP). Furthermore, ultrasonography revealed a higher alleviation in NAFLD grade among LOV-D, compared with SWL-D. This study suggests that adherence to LOV-D for 3 months has beneficial effects on NAFLD improvement, anthropometric measures, glycaemic-related markers, and lipid profiles. [ABSTRACT FROM AUTHOR]

المؤلفون: Raeisi, Tahereh, Mozaffari, Hadis, Sepehri, Nazaninzahra, Darand, Mina, Razi, Bahman, Garousi, Nazila, Alizadeh, Mohammad, Alizadeh, Shahab

المصدر: Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity ; volume 27, issue 3, page 893-911 ; ISSN 1590-1262

مصطلحات موضوعية: Psychiatry and Mental health, Clinical Psychology

الإتاحة: https://doi.org/10.1007/s40519-021-01269-3Test

المؤلفون: Raeisi, Tahereh, Rezaie, Hossein, Darand, Mina, Taheri, Akram, Garousi, Nazila, Razi, Bahman, Roever, Leonardo, Mohseni, Reza, Hussien Mohammed, Shimels, Alizadeh, Shahab

المساهمون: Atkin, Stephen L.

المصدر: PLOS ONE ; volume 16, issue 3, page e0246200 ; ISSN 1932-6203

الوصف: This meta-analysis was performed to resolve the inconsistencies regarding resistin and follistatin levels in women with polycystic ovary syndrome (PCOS) by pooling the available evidence. A systematic literature search using PubMed and Scopus was carried out through November 2020 to obtain all pertinent studies. Weighted mean differences (WMDs) with corresponding 95% confidence intervals (CIs) were calculated to evaluate the strength of the association between the levels of resistin and follistatin with PCOS in the overall and stratified analysis by obesity status. A total of 47 publications, 38 for resistin (2424 cases; 1906 controls) and 9 studies for follistatin (815 cases; 328 controls), were included in the meta-analysis. Resistin levels were significantly higher in PCOS women compared with non-PCOS controls (WMD = 1.96 ng/ml; 95%CI = 1.25–2.67, P≤0.001) as well as in obese PCOS women vs. obese controls, and in non-obese PCOS women compared with non-obese controls, but not in obese PCOS vs. non-obese PCOS patients,. A significantly increased circulating follistatin was found in PCOS patients compared with the controls (WMD = 0.44 ng/ml; 95%CI = 0.30–0.58, P≤0.001) and in non-obese PCOS women compared with non-obese controls and in obese PCOS women vs. obese controls, but, no significant difference in follistatin level was observed in obese PCOS compared with non-obese PCOS women. Significant heterogeneity and publication bias was evident for some analyses. Circulating levels of resistin and follistatin, independent of obesity status, are higher in women with PCOS compared with controls, showing that these adipokines may contribute to the pathology of PCOS.

الإتاحة: https://doi.org/10.1371/journal.pone.0246200Test

المؤلفون: Rashidi, Kamil, Darand, Mina, Garousi, Nazila, Dehghani, Azadeh, Alizadeh, Shahab

المصدر: Complementary Therapies in Medicine ; volume 63, page 102795 ; ISSN 0965-2299

الإتاحة: https://doi.org/10.1016/j.ctim.2021.102795Test
https://api.elsevier.com/content/article/PII:S0965229921001369?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0965229921001369?httpAccept=text/plainTest

المؤلفون: Margiana, Ria, Hamoud Alshahrani, Shadia, Kayumova, Dilrabo, Hussien Radie Alawadi, Ahmed, Hjazi, Ahmed, Alsalamy, Ali, Qasim, Qutaiba A., Juyal, Ashima, Garousi, Nazila

المساهمون: no specific funding

المصدر: International Journal of Environmental Health Research ; volume 34, issue 8, page 2947-2956 ; ISSN 0960-3123 1369-1619

الإتاحة: https://doi.org/10.1080/09603123.2023.2280155Test

المؤلفون: Taheri, Akram, Raeisi, Tahereh, Darand, Mina, Jafari, Alireza, Janmohammadi, Parisa, Razi, Bahman, Mofidi Nejad, Maryam, Lafzi Ghazi, Maryam, Garousi, Nazila, Alizadeh, Shahab

المصدر: Breastfeeding Medicine ; volume 17, issue 1, page 22-32 ; ISSN 1556-8253 1556-8342

مصطلحات موضوعية: Maternity and Midwifery, Obstetrics and Gynecology, Health Policy, Pediatrics

الإتاحة: https://doi.org/10.1089/bfm.2021.0204Test