يعرض 1 - 10 نتائج من 13 نتيجة بحث عن '"Garcia-Luna PP"', وقت الاستعلام: 1.11s تنقيح النتائج
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    الوصف: International scientific experts in food, nutrition, dietetics, endocrinology, physical activity, paediatrics, nursing, toxicology and public health met in Lisbon on 2-4 July 2017 to develop a Consensus on the use of low- and no-calorie sweeteners (LNCS) as substitutes for sugars and other caloric sweeteners. LNCS are food additives that are broadly used as sugar substitutes to sweeten foods and beverages with the addition of fewer or no calories. They are also used in medicines, health-care products, such as toothpaste, and food supplements. The goal of this Consensus was to provide a useful, evidence-based, point of reference to assist in efforts to reduce free sugars consumption in line with current international public health recommendations. Participating experts in the Lisbon Consensus analysed and evaluated the evidence in relation to the role of LNCS in food safety, their regulation and the nutritional and dietary aspects of their use in foods and beverages. The conclusions of this Consensus were: (1) LNCS are some of the most extensively evaluated dietary constituents, and their safety has been reviewed and confirmed by regulatory bodies globally including the World Health Organisation, the US Food and Drug Administration and the European Food Safety Authority; (2) Consumer education, which is based on the most robust scientific evidence and regulatory processes, on the use of products containing LNCS should be strengthened in a comprehensive and objective way; (3) The use of LNCS in weight reduction programmes that involve replacing caloric sweeteners with LNCS in the context of structured diet plans may favour sustainable weight reduction. Furthermore, their use in diabetes management programmes may contribute to a better glycaemic control in patients, albeit with modest results. LNCS also provide dental health benefits when used in place of free sugars; (4) It is proposed that foods and beverages with LNCS could be included in dietary guidelines as alternative options to products sweetened with free sugars; (5) Continued education of health professionals is required, since they are a key source of information on issues related to food and health for both the general population and patients. With this in mind, the publication of position statements and consensus documents in the academic literature are extremely desirable.

    وصف الملف: application/pdf

    العلاقة: 2072-6643

  2. 2
    دورية أكاديمية

    المصدر: International Journal of Women's Health, Vol Volume 8, Pp 721-729 (2016)

    الوصف: Irene González,1 Albert Lecube,2 Miguel Ángel Rubio,3 Pedro Pablo García-Luna4 1Endocrinology and Nutrition Department, Complejo Hospitalario Universitario de Huelva, Huelva, Spain; 2Endocrinology and Nutrition Department, Arnau de Vilanova University Hospital, Lleida Biomedicine Research Institute (IRB-Lleida), CIBER in Diabetes and Associated Metabolic Disorders (CIBERDEM), Lleida University, Lleida, Spain; 3Endocrinology and Nutrition Department, Hospital Clínico San Carlos, IDISSC, Madrid, Spain; 4Endocrinology and Nutrition Department, Hospitales Universitarios Virgen del Rocío, Seville, Spain Abstract: The significant increase in the prevalence of obesity has led to an increase in the number of obese women who become pregnant. In this setting, in recent years, there has been an exponential rise in the number of bariatric procedures, with approximately half of them performed in women of childbearing age, and a remarkable surge in the number of women who become pregnant after having undergone bariatric surgery (BS). These procedures entail the risk of nutritional deficiencies, and nutrition is a crucial aspect during pregnancy. Therefore, knowledge and awareness of the consequences of these techniques on maternal and fetal outcomes is essential. Current evidence suggests a better overall obstetric outcome after BS, in comparison to morbid obese women managed conservatively, with a reduction in the prevalence of gestational diabetes mellitus, pregnancy-associated hypertensive disorders, macrosomia, and congenital defects. However, the risk of potential maternal nutritional deficiencies and newborns small for gestational age cannot be overlooked. Results concerning the incidence of preterm delivery and the number of C-sections are less consistent. In this paper, we review the updated evidence regarding the impact of BS on pregnancy. Keywords: bariatric surgery, pregnancy, maternal and fetal outcomes, gestational diabetes mellitus, small for gestational age

  3. 3
    دورية أكاديمية

    المساهمون: Alimentació, Nutrició, Creixement i Salut Mental, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili

    جغرافية الموضوع: Castellà

    الوقت: 0025-7753

    الوصف: SEEDO consensus ' 2000 for the evaluation of overweight and obesity and the establishment of criteria for therapeutic intervention. ; Consenso SEEDO' 2000 para la evaluación del sobrepeso y la obesidad y el establecimiento de criterios de intervención terapéutica.

    وصف الملف: 10180 kb

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    المؤلفون: James, Wp, Caterson, Id, Coutinho, W, Finer, N, VAN GAAL LF, Maggioni, Ap, TORP-PEDERSEN, C, Sharma, Am, Shepherd, Gm, Rode, Ra, Renz, Cl, Van Gaal LF, Torp-Pedersen, C, Pepine, C, Pocock, S, Drexler, H, Swedberg, K, Sleight, P, Armstrong, P, Kerr, D, Dagenais, G, Brophy, J, Avezum, A, Bogaty, P, Fabbri, G, Galli, M, Hildebrandt, P, Mann, J, Ostergren, J, Sherman, D, Zannad, F, Colquhoun, D, Hollanders, G, e Forti A, Costa, Cifkova, R, Toubro, S, Ziegler, O, Scherbaum, Wa, Jordan, J, Halmy, L, Ferrannini, E, Santini, F, Gonzalez, C, Narkiewicz, K, Hancu, N, Payer, J, Pascual, J, Wilding, J, Campbell, L, Carey, D, Gerstman, M, Karrasch, J, Lefkovits, J, Marks, J, Marks, S, Moses, R, Phillips, P, Proietto, J, Roberts, D, Roberts-Thomson, P, Shaw, J, Simpson, R, Singh, B, Singleton Jeffries, W, Stuckey, B, Boland, J, Brohet, C, Coucke, F, Dendale, P, Jouret, G, Kolanowski, J, Kutnowski, M, Martens, F, Muls, E, Peiffer, F, Penninckx, H, Scheen, A, Schoors, D, Vaerenberg, M, Van Cleemput, J, Van Crombrugge, P, Van Kuyk, M, Verhaegen, A, Wollaert, B, de Albuquerque DC, Appolinario, J, de Godoy Matos AF, Gross, Jl, Halpern, A, Kerr Saraiva JF, Milagres, R, Repetto, G, Suplicy, Hl, Zanella, Mt, Bednarova, J, Cepelak, V, Cerny, P, Hainer, V, Havranek, P, Homza, M, Jansa, P, Karlicek, M, Kolesar, J, Kotik, I, Kucera, D, Kuchar, J, Kunc, M, Kvapil, M, Linhart, A, Machova, V, Matuska, J, Oral, I, Pavlas, J, Pesatova, S, Povolny, J, Semrad, B, Smetana, K, Soucek, M, Svacina, S, Tesinsky, P, Urbanek, R, Wasserburger, B, Zachoval, R, Zahumensky, E, Zidkova, E, Astrup, A, Dominguez, H, Faber, J, Hilderbrant, P, Kober, L, Perrild, H, Richelsen, B, Sogaard, P, Svendsen, Ol, Urhammer, S, Archambeaud, F, Basdevant, A, Borys, Jm, Bringer, J, Brunetiere, C, Charpentier, G, Cocaul-André, M, Dabadie, H, Dubreuil, A, Estour, B, Gautier, Jf, Gibault, T, Halimi, S, Hespel, Jp, Issa Sayegh, M, Krempf, M, Laville, M, Lecerf, Jm, Louvet, Jp, Penfornis, A, Ritz, P, Schlienger, Jl, Schmitt, B, Valensi, P, Baar, M, Beermann, J, Bock, M, Boenner, G, Dammann, Hg, Diehm, C, Ditschuneit, H, Gadow, J, Gehlhar, S, Gessner, S, Guthersohn, A, Hamann, A, Hanefeld, M, Hasenfuss, G, Herzner, A, Heun, Kc, Heufelder, Ae, Hohensee, H, Jacob, S, Krings, P, Krätzig, B, Krosse, B, Lehmann, Rt, Mindt-Prüfert, S, Maisch, B, Pfeiffer, Af, Richard, F, Rose, B, Schmidt, E, Scholze, J, Schreckenberg, A, Stuebler, P, Walter, J, Wirth, A, Wunderlich, J, Abraham, G, Altorjay, A, Augusztin, G, Csaszar, A, Czuriga, I, Dinnyes, J, Gero, L, Gyimesi, A, Janosi, A, Kovacs, I, Liziczai, I, Majtenyi, A, Medvegy, M, Nadhazi, Z, Pados, G, Polak, G, Ronaszeki, A, Sido, Z, Simon, K, Anzà, C, Bevilacqua, M, Bosello, O, Chiariello, M, Cordera, R, Ferrari, E, Frittitta, L, Giorgino, R, Liuzzi, A, Malinverni, C, Di Mario, U, Melchionda, N, Occhi, G, Perticone, F, Pinchera, A, Pinelli, G, Rovera, G, Santeusanio, F, Urbinati, S, Alpizar-Salazar, M, Carrillo-Ortega, E, Fanghanel Salmon, G, Laviada-Molina, Ha, Madero, Ma, Rodriguez, G, Saldate, C, Sanchez-Castillo, Cp, Violante, Rm, Wacher, N, Zayas-Jaime, Fj, Zuniga-Guajardo, S, Adamiec, R, Banasiak, W, Chrusciel, P, Derlaga, B, Gebala, A, Gessek, J, Janik, K, Janion, M, Kalina, Z, Kozlowski, A, Kusnierz, B, Majcher, Z, Miekus, P, Niegowska, J, Okopien, B, Ostrowska, L, Pasowicz, M, Piepiorka, M, Pluta, W, Polaszewska-Muszynska, M, Ponikowski, P, Pupek-Musialik, D, Sawicki, A, Sobocik, H, Stankiewicz, A, Szpajer, M, Trojnar, R, Tykarski, A, Wrabec, K, Wyrzkowski, B, Zahorska-Markiewicz, B, Zalewski, M, Carrageta, M, Mendes Pedro MM, Parente Martins LM, dos Santos, L, Babes, A, Creteanu, G, Dan, Ga, Dragulescu, Si, Graur, M, Tirgoviste, Ci, Morosanu, M, Mota, M, Paveliu, Fs, Radoi, M, Ranetti, A, Totoian, I, Andre, I, Bugan, V, Cencarik, J, Csala, L, Farsky, S, Gonsorcik, J, Kamensky, G, Kmec, J, Krahulec, B, Kurian, R, Macek, V, Majercak, I, Micko, K, Mokan, M, Riecansky, I, Sojka, G, Uhliar, R, Urgeova, L, Vancik, J, Baro, Fm, Barrios Merino, A, Borras, Jl, Caixas, A, Cuatrecasas Cambra, G, Dominguez Escribano JR, Duran Garcia, S, Escobar-Jimenez, L, Esteva de Antonio, I, Formiguera Sala, X, Garcia-Luna, Pp, Garcia Robles, R, Gonzalez Albarran, O, Hernandez-Mijares, A, Martin Hidalgo, A, Masmiquel Comas, L, Morales Perez, F, Moreno Esteban, B, Pascual Izuel JM, Redon Mas, J, Ricart, W, Rubio, Ma, Ruilope, Lm, Salas-Salvado, J, Terroba Larumbe, M, Tinahones, F, de la Torre Casares ML, Vidal Cortada, J, Zuniga-Perez Lemaur, M, Abdulhakim, Ee, Adler, A, Barnett, Ah, Bodmer, C, Campbell, Iw, Chowdhury, T, Cleland, J, Cook, Rc, Dinneen, S, Donnachie, H, Haslam, Dw, Hillis, Gs, Horne, M, Howarth, Dj, Hughes, E, Jackson, S, Jones, Sc, Jones, Th, Kumar, S, Lean, M, Maroni, J, Mcinnes, G, Middleton, A, Morris, A, Newcombe, G, O'Kane, Kp, Pavel, Ic, Pawa, R, Perry, C, Pitts, C, Raja, A, Reckless, J, Robinson, J, Sarmiento, R, Soo, Sc, Taylor, S, Thomas, Ho, Thomson, Ma, Wilkins, M.

    المصدر: The New England journal of medicine
    James, W P T, Caterson, I D, Coutinho, W, Finer, N, Van Gaal, L F, Maggioni, A P, Torp-Pedersen, C T, Sharma, A M, Shepherd, G M, Rode, R A, Renz, C L, SCOUT Investigators & Richelsen, B 2010, ' Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects ', Briefings from the New England Journal of Medicine, vol. 363, no. 10, pp. 905-17 . https://doi.org/10.1056/NEJMoa1003114Test

    الوصف: Background The long-term effects of sibutramine treatment on the rates of cardiovascular events and cardiovascular death among subjects at high cardiovascular risk have not been established. Methods We enrolled in our study 10,744 overweight or obese subjects, 55 years of age or older, with preexisting cardiovascular disease, type 2 diabetes mellitus, or both to assess the cardiovascular consequences of weight management with and without sibutramine in subjects at high risk for cardiovascular events. All the subjects received sibutramine in addition to participating in a weight-management program during a 6-week, single-blind, lead-in period, after which 9804 subjects underwent random assignment in a double-blind fashion to sibutramine (4906 subjects) or placebo (4898 subjects). The primary end point was the time from randomization to the first occurrence of a primary outcome event (nonfatal myocardial infarction, nonfatal stroke, resuscitation after cardiac arrest, or cardiovascular death). Results The mean duration of treatment was 3.4 years. The mean weight loss during the lead-in period was 2.6 kg; after randomization, the subjects in the sibutramine group achieved and maintained further weight reduction (mean, 1.7 kg). The mean blood pressure decreased in both groups, with greater reductions in the placebo group than in the sibutramine group (mean difference, 1.2/1.4 mm Hg). The risk of a primary outcome event was 11.4% in the sibutramine group as compared with 10.0% in the placebo group (hazard ratio, 1.16; 95% confidence interval [CI], 1.03 to 1.31; P=0.02). The rates of nonfatal myocardial infarction and nonfatal stroke were 4.1% and 2.6% in the sibutramine group and 3.2% and 1.9% in the placebo group, respectively (hazard ratio for nonfatal myocardial infarction, 1.28; 95% CI, 1.04 to 1.57; P=0.02; hazard ratio for nonfatal stroke, 1.36; 95% CI, 1.04 to 1.77; P=0.03). The rates of cardiovascular death and death from any cause were not increased. Conclusions Subjects with preexisting cardiovascular conditions who were receiving long-term sibutramine treatment had an increased risk of nonfatal myocardial infarction and nonfatal stroke but not of cardiovascular death or death from any cause. (Funded by Abbott; ClinicalTrials.gov number, NCT00234832.)

    وصف الملف: application/pdf

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    دورية أكاديمية

    المساهمون: Perez Jimenez, F, Alvarez de Cienfuegos, G, Badimon, L, Barja, G, Battino, M, Blanco, A, Bonanome, A, Colomer, R, Corella Piquer, D, Covas, I, Chamorro Quiros, J, Escrich, E, Gaforio, Jj, Garcia Luna, Pp, Hidalgo, L, Kafatos, A, Kris Etherton, Pm, Lairon, D, Lamuela Raventos, R, Lopez Miranda, J, Lopez Segura, F, Martinez Gonzalez, Ma, Mata, P, Mataix, J, Ordovas, J, Osada, J, Pacheco Reyes, R, Perucho, M, Pineda Priego, M, Quiles, Jl, Ramirez Tortosa, Mc, Ruiz Gutierrez, V, Sanchez Rovira, P, Solfrizzi, V, Soriguer Escofet, F, de la Torre Fornell, R, Trichopoulos, A, Villalba Montoro, Jm, Villar Ortiz, Jr, Visioli, Francesco

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/16008542; info:eu-repo/semantics/altIdentifier/wos/WOS:000230293600002; volume:35; journal:EUROPEAN JOURNAL OF CLINICAL INVESTIGATION; http://hdl.handle.net/11577/3156774Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-22244490340

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    دورية أكاديمية

    المساهمون: Pérez Jiménez, F, Álvarez De Cienfuegos, G, Badimón, L, Barja, G, Battino, Maurizio, Blanco, A, Bonanome, A, Colomer, R, Corella Piquer, D, Covas, I, Chamorro Quirós, J, Escrich, E, Gaforio, Jj, García Luna, Pp, Hidalgo Ardanaz, L, Kafatos, A, Kris Etherton, Pm, Lairon, D, Lamuela Raventós, R, López Miranda, J, López Segura, F, Martínez González, Ma, Mata, P, Mataix, J, Ordovás, J, Osada, J, Pacheco Reyes, R, Perucho, M, Pineda Priego, M, Quiles, Jl, Ramírez Tortosa, Mc, Ruiz Gutiérrez, V, Sánchez Rovira, P, Solfrizzi, V, Soriguer Escofet, F, De La Torre Fornell, R, Trichopoulos, A, Villalba Montoro, Jm, Villar Ortiz, Jr, Visioli, F.

    الوصف: Aging represents a great concern in developed countries because the number of people involved and the pathologies related with it, like atherosclerosis, Parkinson, Alzheimer, vascular dementia, cognitive decline, diabetes and cancer. Epidemiological studies suggest that a Mediterranean diet (which is rich in virgin olive oil) decreases the risk of cardiovascular disease. The Mediterranean diet, rich in virgin olive oil, improves the major risk factors for cardiovascular disease, such as the lipoprotein profile, blood pressure, glucose metabolism antiantithrombotic profile. Endothelial function, inflammation and oxidative stress are also positively modulated. Some of these effects are attributed to minor components of virgin olive oil. Therefore, the definition of the Mediterranean diet should include virgin olive oil. Different observational studies conducted in humans have shown that the intake of monounsaturated fat may be protective against age-related cognitive decline and Alzheimer's disease. Microconstituents from virgin olive oil are bioavailable in humans and have shown antioxidant properties and capacity to improve endothelial function. Furthermore, they are also able to modify the haemostasis, showing antithrombotic properties. In countries in which the populations fulfilled a typical Mediterranean diet, such as Spain, Greece, and Italy, where virgin olive oil is the principal source of fat, cancer incidence rates are lower than in Northern European countries. The protective effect of virgin olive oil can be most important in the first decades of life, which suggests that the dietetic benefit of virgin olive oil intake should be initiated before puberty, and maintained through life. The more recent studies consistently support that the Mediterranean diet, based in virgin olive oil, is compatible with a healthier aging and increased longevity. However, despite the significant advances of the recent years, the final proof about the specific mechanisms and contributing role of the different components of ...

    العلاقة: volume:3; issue:4; firstpage:212; lastpage:217; numberofpages:6; journal:REVISTA ESPAÑOLA DE OBESIDAD; http://hdl.handle.net/11566/80770Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-33646865487

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    دورية أكاديمية

    المؤلفون: JAMES WP, CATERSON ID, COUTINHO W, FINER N, VAN GAAL LF, MAGGIONI AP, TORP-PEDERSEN C, SHARMA AM, SHEPHERD GM, RODE RA, RENZ CL, James WP, Caterson ID, Coutinho W, Finer N, Van Gaal LF, Maggioni AP, Sharma AM, Torp-Pedersen C, Pepine C, Pocock S, Drexler H, Swedberg K, Sleight P, Armstrong P, Kerr D, Dagenais G, Brophy J, Avezum A, Bogaty P, Fabbri G, Galli M, Hildebrandt P, Mann J, Ostergren J, Sherman D, Zannad F, Colquhoun D, Hollanders G, Costa e Forti A, Cifkova R, Toubro S, Ziegler O, Scherbaum WA, Jordan J, Halmy L, Ferrannini E, Santini F, Gonzalez C, Narkiewicz K, Hancu N, Payer J, Pascual J, Wilding J, Campbell L, Carey D, Gerstman M, Karrasch J, Lefkovits J, Marks J, Marks S, Moses R, Phillips P, Proietto J, Roberts D, Roberts-Thomson P, Shaw J, Simpson R, Singh B, Singleton Jeffries W, Stuckey B, Boland J, Brohet C, Coucke F, Dendale P, Jouret G, Kolanowski J, Kutnowski M, Martens F, Muls E, Peiffer F, Penninckx H, Scheen A, Schoors D, Vaerenberg M, Van Cleemput J, Van Crombrugge P, Van Kuyk M, Verhaegen A, Wollaert B, de Albuquerque DC, Appolinario J, de Godoy Matos AF, Gross JL, Halpern A, Kerr Saraiva JF, Milagres R, Repetto G, Suplicy HL, Zanella MT, Bednarova J, Cepelak V, Cerny P, Hainer V, Havranek P, Homza M, Jansa P, Karlicek M, Kolesar J, Kotik I, Kucera D, Kuchar J, Kunc M, Kvapil M, Linhart A, Machova V, Matuska J, Oral I, Pavlas J, Pesatova S, Povolny J, Semrad B, Smetana K, Soucek M, Svacina S, Tesinsky P, Urbanek R, Wasserburger B, Zachoval R, Zahumensky E, Zidkova E, Astrup A, Dominguez H, Faber J, Hilderbrant P, Kober L, Perrild H, Richelsen B, Sogaard P, Svendsen OL, Urhammer S, Archambeaud F, Basdevant A, Borys JM, Bringer J, Brunetiere C, Charpentier G, Cocaul-André M, Dabadie H, Dubreuil A, Estour B, Gautier JF, Gibault T, Halimi S, Hespel JP, Issa Sayegh M, Krempf M, Laville M, Lecerf JM, Louvet JP, Penfornis A, Ritz P, Schlienger JL, Schmitt B, Valensi P, Baar M, Beermann J, Bock M, Boenner G, Dammann HG, Diehm C, Ditschuneit H, Gadow J, Gehlhar S, Gessner S, Guthersohn A, Hamann A, Hanefeld M, Hasenfuss G, Herzner A, Heun KC, Heufelder AE, Hohensee H, Jacob S, Krings P, Krätzig B, Krosse B, Lehmann RT, Mindt-Prüfert S, Maisch B, Pfeiffer AF, Richard F, Rose B, Schmidt E, Scholze J, Schreckenberg A, Stuebler P, Walter J, Wirth A, Wunderlich J, Abraham G, Altorjay A, Augusztin G, Csaszar A, Czuriga I, Dinnyes J, Gero L, Gyimesi A, Janosi A, Kovacs I, Liziczai I, Majtenyi A, Medvegy M, Nadhazi Z, Pados G, Polak G, Ronaszeki A, Sido Z, Simon K, Anzà C, Bevilacqua M, Bosello O, Chiariello M, Cordera R, Ferrari E, Frittitta L, Giorgino R, Liuzzi A, Malinverni C, Di Mario U, Melchionda N, Occhi G, Perticone F, Pinchera A, Pinelli G, Rovera G, Santeusanio F, Urbinati S, Alpizar-Salazar M, Carrillo-Ortega E, Fanghanel Salmon G, Laviada-Molina HA, Madero MA, Rodriguez G, Saldate C, Sanchez-Castillo CP, Violante RM, Wacher N, Zayas-Jaime FJ, Zuniga-Guajardo S, Adamiec R, Banasiak W, Chrusciel P, Derlaga B, Gebala A, Gessek J, Janik K, Janion M, Kalina Z, Kozlowski A, Kusnierz B, Majcher Z, Miekus P, Niegowska J, Okopien B, Ostrowska L, Pasowicz M, Piepiorka M, Pluta W, Polaszewska-Muszynska M, Ponikowski P, Pupek-Musialik D, Sawicki A, Sobocik H, Stankiewicz A, Szpajer M, Trojnar R, Tykarski A, Wrabec K, Wyrzkowski B, Zahorska-Markiewicz B, Zalewski M, Carrageta M, Mendes Pedro MM, Parente Martins LM, dos Santos L, Babes A, Creteanu G, Dan GA, Dragulescu SI, Graur M, Tirgoviste CI, Morosanu M, Mota M, Paveliu FS, Radoi M, Ranetti A, Totoian I, Andre I, Bugan V, Cencarik J, Csala L, Farsky S, Gonsorcik J, Kamensky G, Kmec J, Krahulec B, Kurian R, Macek V, Majercak I, Micko K, Mokan M, Riecansky I, Sojka G, Uhliar R, Urgeova L, Vancik J, Baro FM, Barrios Merino A, Borras JL, Caixas A, Cuatrecasas Cambra G, Dominguez Escribano JR, Duran Garcia S, Escobar-Jimenez L, Esteva de Antonio I, Formiguera Sala X, Garcia-Luna PP, Garcia Robles R, Gonzalez Albarran O, Hernandez-Mijares A, Martin Hidalgo A, Masmiquel Comas L, Morales Perez F, Moreno Esteban B, Pascual Izuel JM, Redon Mas J, Ricart W, Rubio MA, Ruilope LM, Salas-Salvado J, Terroba Larumbe M, Tinahones F, de la Torre Casares ML, Vidal Cortada J, Zuniga-Perez Lemaur M, Abdulhakim EE, Adler A, Barnett AH, Bodmer C, Campbell IW, Chowdhury T, Cleland J, Cook RC, Dinneen S, Donnachie H, Haslam DW, Hillis GS, Horne M, Howarth DJ, Hughes E, Jackson S, Jones SC, Jones TH, Kumar S, Lean M, Maroni J, McInnes G, Middleton A, Morris A, Newcombe G, O'Kane KP, Pavel IC, Pawa R, Perry C, Pitts C, Raja A, Reckless J, Robinson J, Sarmiento R, Soo SC, Taylor S, Thomas HO, Thomson MA, Wilkins M.

    المساهمون: James, Wp, Caterson, Id, Coutinho, W, Finer, N, VAN GAAL, Lf, Maggioni, Ap, TORP-PEDERSEN, C, Sharma, Am, Shepherd, Gm, Rode, Ra, Renz, Cl, Van Gaal, Lf, Torp-Pedersen, C, Pepine, C, Pocock, S, Drexler, H, Swedberg, K, Sleight, P, Armstrong, P, Kerr, D, Dagenais, G, Brophy, J, Avezum, A, Bogaty, P, Fabbri, G, Galli, M, Hildebrandt, P, Mann, J, Ostergren, J, Sherman, D, Zannad, F, Colquhoun, D, Hollanders, G, Costa, e Forti A, Cifkova, R, Toubro, S, Ziegler, O, Scherbaum, Wa, Jordan, J, Halmy, L, Ferrannini, E, Santini, F, Gonzalez, C, Narkiewicz, K, Hancu, N, Payer, J, Pascual, J, Wilding, J, Campbell, L, Carey, D, Gerstman, M, Karrasch, J, Lefkovits, J, Marks, J, Marks, S, Moses, R, Phillips, P, Proietto, J, Roberts, D, Roberts-Thomson, P, Shaw, J, Simpson, R, Singh, B, Singleton Jeffries, W, Stuckey, B, Boland, J, Brohet, C, Coucke, F, Dendale, P, Jouret, G, Kolanowski, J, Kutnowski, M, Martens, F, Muls, E, Peiffer, F, Penninckx, H, Scheen, A, Schoors, D, Vaerenberg, M, Van Cleemput, J, Van Crombrugge, P, Van Kuyk, M, Verhaegen, A, Wollaert, B, de Albuquerque, Dc, Appolinario, J, de Godoy Matos, Af, Gross, Jl, Halpern, A, Kerr Saraiva, Jf, Milagres, R

    الوصف: BACKGROUND: The long-term effects of sibutramine treatment on the rates of cardiovascular events and cardiovascular death among subjects at high cardiovascular risk have not been established. METHODS: We enrolled in our study 10,744 overweight or obese subjects, 55 years of age or older, with preexisting cardiovascular disease, type 2 diabetes mellitus, or both to assess the cardiovascular consequences of weight management with and without sibutramine in subjects at high risk for cardiovascular events. All the subjects received sibutramine in addition to participating in a weight-management program during a 6-week, single-blind, lead-in period, after which 9804 subjects underwent random assignment in a double-blind fashion to sibutramine (4906 subjects) or placebo (4898 subjects). The primary end point was the time from randomization to the first occurrence of a primary outcome event (nonfatal myocardial infarction, nonfatal stroke, resuscitation after cardiac arrest, or cardiovascular death). RESULTS: The mean duration of treatment was 3.4 years. The mean weight loss during the lead-in period was 2.6 kg; after randomization, the subjects in the sibutramine group achieved and maintained further weight reduction (mean, 1.7 kg). The mean blood pressure decreased in both groups, with greater reductions in the placebo group than in the sibutramine group (mean difference, 1.2/1.4 mm Hg). The risk of a primary outcome event was 11.4% in the sibutramine group as compared with 10.0% in the placebo group (hazard ratio, 1.16; 95% confidence interval [CI], 1.03 to 1.31; P=0.02). The rates of nonfatal myocardial infarction and nonfatal stroke were 4.1% and 2.6% in the sibutramine group and 3.2% and 1.9% in the placebo group, respectively (hazard ratio for nonfatal myocardial infarction, 1.28; 95% CI, 1.04 to 1.57; P=0.02; hazard ratio for nonfatal stroke, 1.36; 95% CI, 1.04 to 1.77; P=0.03). The rates of cardiovascular death and death from any cause were not increased. CONCLUSIONS: Subjects with preexisting cardiovascular ...

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/20818901; info:eu-repo/semantics/altIdentifier/wos/WOS:000281441500004; volume:363; firstpage:905; lastpage:917; numberofpages:13; journal:NEW ENGLAND JOURNAL OF MEDICINE; http://hdl.handle.net/11568/141621Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-77956284607

  8. 8
  9. 9
    دورية أكاديمية

    المساهمون: Grupo NADYA-SENPE, Wanden-Berghe,C FISABIO-Hospital General Universitario de Alicante. Universidad Miguel Hernández (Elche), Alicante. Cuerda Compes,JC Hospital Gregorio Marañón. Burgos Peláez,R Hospital Vall d’Hebrón, Barcelona. Gómez Candela,C Hospital La Paz. Virgili Casas,N Hospital Universitario Bellvitge, L’Hospitalet de Llobregat, Barcelona. Pérez de la Cruz,A Hospital Virgen de las Nieves, Granada. Moreno Villares,JM Hospital Universitario 12 de Octubre, Madrid. Carabaña Pérez,F Hospital Ramón y Cajal, Madrid. Garde Orbaiz,C Hospital Universitario Donostia, Guipuzkoa. Martínez Faedo,C Hospital Universitario Central de Asturias. Penacho Lázaro,MA Hospital El Bierzo, Ponferrada, León. Gonzalo Marín,M Hospital Universitario Carlos Haya. Málaga. García Luna,PP Hospital Universitario Virgen del Rocío, Sevilla. Matía Martín,P Hospital Clínico San Carlos, Madrid. Sanz Paris,A Hospital Universitario Miguel Servet, Zaragoza. Luengo Pérez,LM Hospital Infanta Cristina, Badajoz. Martín Folgueras,T Complejo Hospitalario Universitario de Canarias, Santa Cruz de Tenerife. García Zafra,MV Hospital Universitario Virgen de la Arrixaca, Murcia. Álvarez Hernández Hospital Príncipe de Asturias ,Alcalá de Henares, Madrid. Campos Martín,C Hospital Universitario Virgen Macarena, Sevilla. Suárez Llanos,JP Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife. Zugasti,A Hospital Virgen del Camino, Pamplona. Apezetxea Celaya,A Hospital Basurto, Bilbao. Urgeles Planella,JR Hospital Universitario Son Espases, Palma de Mallorca. Laborda González,L Hospital de Cruce, Bilbao. Sánchez-Vilar Burdiel,O Fundación Jiménez Díaz, Madrid. Joaquín Ortiz,C Hospital Germans Trias i Pujol, Barcelona. Martínez Costa,C Hospital Clínico Universitario, Valencia. Vidal Casariego,A Complejo Asistencial de León. Leyes García,P Hospital Clinic, Barcelona. Ponce González,MA Hospital Universitario Dr Negrín, Gran Canaria. Gil Martínez,MC Hospital Central de la Defensa Gomez Ulla, Madrid. Sánchez Martos,EA Corporació Sanitària Parc Taulí, Barcelona. del Olmo García,MD Hospital Universitario Severo Ochoa , Leganés, Madrid. Díaz Guardiola,P Hospital Infanta Sofía, San Sebastian de los Reyes, Madrid. Spain.

    مصطلحات موضوعية: Home parenteral nutrition, Parenteral nutrition, Nutritional support, Home care services, Registries, Epidemiolgy, Nutrición parenteral domiciliaria, Nutrición parenteral, Soporte nutricional, Cuidados domiciliarios, Registros, Epidemiología, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult, Medical Subject Headings::Named Groups::Persons::Age Groups::Child, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Follow-Up Studies, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases, Medical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Intestinal Obstruction, Medical Subject Headings::Disciplines and Occupations::Social Sciences::Sociology::Minority Groups, Medical Subject Headings::Diseases::Neoplasms, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Registries, Medical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Malabsorption Syndromes::Short Bowel Syndrome, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Feeding Methods::Parenteral Nutrition::Parenteral Nutrition, Home, Medical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Mesenteric Ischemia

    الوصف: Objetivo: comunicar los datos del registro de Nutrición Parenteral Domiciliaria (NPD) del grupo de trabajo NADYA-SENPE del años 2013. Material y métodos: recopilación de los datos del registro “on-line” introducidos por los colaboradores del grupo NADYA responsables del seguimiento de la NPD desde el 1 de enero de 2013 al 31 de diciembre de 2013. Resultados: se registraron 197 pacientes, procedentes de 35 hospitales, lo que representa una tasa de 4,22 pacientes/ millón habitantes/año 2013, con 202 episodios de NPD. La edad media de los 189 pacientes mayores de 14 años fue de 53 años (IIQ 40 – 64), y en los niños de 7 meses (IIQ 6 – 35,5). La patología más frecuente en los adultos fue la neoplasia (30,7%) seguida por otras patologías (20,1%) y la isquemia mesentérica (12,7%). En el 35,4% de los casos el motivo de indicación fue el síndrome de intestino corto, seguido de la obstrucción intestinal (25,9%). En los niños el diagnóstico más frecuente fueron las alteraciones congénitas intestinales y ‘otros diagnósticos’, ambas con un 37,5 %, y la causa de la indicación el síndrome de intestino corto y la obstrucción intestinal, que se repartieron el 50% de la muestra. Los catéteres más utilizados fueron los tunelizados (50%) y los reservorios subcutáneos (27,7%). Las complicaciones más frecuentes fueron las sépticas, relacionadas con el catéter, con una tasa de 0,74 infecciones/1.000 días de NPD. La duración de la NPD presentó una mediana de 1,69 años. Durante el año finalizaron 86 episodios, la principal causa de la finalización en adultos fue el fallecimiento (45%) seguido del ‘paso a la vía oral’ (43,75%) y en los niños a la inversa 66,7% pasan a vía oral y 16,7% fallecen. Se consideraron candidatos para trasplante intestinal el 15% de los pacientes, siendo proporcionalmente los candidatos niños, p-valor 0,002. Conclusiones: se observa un aumento progresivo de los centros participantes y de los pacientes registrados respecto a años anteriores. El principal grupo patológico sigue siendo oncológico, ocupando el ...

    وصف الملف: application/pdf

    العلاقة: http://www.aulamedica.es/gdcr/index.php/nh/article/view/9052Test; Wanden-Berghe C, Cuerda Compes JC, Burgos Peláez R, Gómez Candela C, Virgili Casas N, Pérez de la Cruz A, et al. A Home and Ambulatory Artificial Nutrition (NADYA) group report, Home Parenteral Nutrition in Spain, 2015. Nutr Hosp; 31(6):2533-8; http://hdl.handle.net/10668/2224Test

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    دورية أكاديمية

    المساهمون: González Navarro,I, Pereira Cunill,JL, Serrano Aguayo,P, García Luna,PP Unidad de Nutrición Clínica y Dietética, Unidad de Gestión Clínica de Endocrinología y Nutrición, Hospital Universitario Virgen del Rocío, Sevilla, España. Morales Conde,S Unidad de Cirugía Laparoscópica, Servicio de Cirugía General y Digestiva,Hospital Universitario Virgen del Rocío, Sevilla, España. Martos Martínez,JM Unidad de Cirugía Endocrina, Servicio de Cirugía General y Digestiva, Hospital Universitario Virgen del Rocío, Sevilla, España.

    مصطلحات موضوعية: Pregnancy, Obesity, Bariatric surgery, Biliopancreatic diversion, Roux-en-Y gastric bypass, Gestación, Obesidad, Cirugía bariátrica, Derivación biliopancreática, Bypass gástrico, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Bariatric Surgery, Operative::Digestive System Surgical Procedures::Biliopancreatic Diversion, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Birth Weight, Medical Subject Headings::Check Tags::Female, Medical Subject Headings::Anatomy::Embryonic Structures::Fetus, Operative::Bariatric Surgery::Gastric Bypass, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Diseases::Cardiovascular Diseases::Vascular Diseases::Hypertension, Medical Subject Headings::Named Groups::Persons::Age Groups::Infant::Infant, Newborn, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Nutritional Status, Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity, Medical Subject Headings::Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy, Medical Subject Headings::Diseases::Female Urogenital Diseases and Pregnancy Complications::Pregnancy Complications, Medical Subject Headings::Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy::Pregnancy Outcome, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Growth Substances::Micronutrients::Vitamins, Medical Subject Headings::Named Groups::Persons::Age Groups::Adult

    الوصف: English Abstract; Journal Article; ; Introducción: La obesidad es la enfermedad metabòlica más frecuente en el mundo y conlleva múltiples co-morbilidades, siendo la cirugía bariátrica (CB) una opción terapéutica cuando fallan las medidas clásicas. La mitad de los pacientes intervenidos son mujeres en edad fértil y está demostrado que la obesidad se asocia a peores resultados obstétricos y fetales. Dado que el estado nutricional se ve afectado por la CB y es un factor esencial para el adecuado desarrollo del embarazo, el objetivo de nuestro trabajo es valorar los efectos de la CB sobre la gestación en mujeres obesas intervenidas. Material y métodos: Seguimiento de 10 mujeres y 15 gestaciones tras CB durante el periodo 2003-2009. Se realizaron visitas trimestrales en consultas de Nutrición y Obstetricia, con evaluación clínica y de laboratorio en cada una. Resultados: Se evidenció deficiencia de hierro en el 80% de las gestaciones, de vitamina D en el 46,7%, de vitamina A en el 20%, de vitamina E en el 13,3% y de vitamina B12 en el 26,7%. No hubo complicaciones durante la gestación salvo un caso de hiperemesis gravidica. Hubo 9 partos de recién nacidos vivos sin malformaciones de los cuales 3 fueron recién nacidos pequeños para la edad gestacional (RNPEG) y uno presentó neumonía por aspiración de meconio. Hubo 3 abortos y un parto prematuro con feto muerto. Conclusiones: En nuestro grupo de estudio hubo menos complicaciones durante la gestación comparado con lo descrito en obesas no operadas y similares a la población general. ; BACKGROUND Obesity is the most frequent metabolic disease in the World, and is associated with several comorbidities. Bariatric procedures arise as a promising treatment when classical approach is ineffective. Half of the operated patients are reproductive-aged women and there is evidence that obesity is related to worse maternal and fetal outcomes. Because nutritional status is affected by bariatric surgery and is a vital component during pregnancy, the aim of our study is to asses the ...

    وصف الملف: application/pdf

    العلاقة: http://www.aulamedica.es/gdcr/index.php/nh/article/view/4998Test; González Navarro I, Pereira Cunill JL, Serrano Aguayo P, Morales Conde S, Martos Martínez JM, García Luna PP. Resultados materno-fetales de la gestación tras cirugía bariátrica. Nutr Hosp. 2011; 26(2):376-83; http://hdl.handle.net/10668/2186Test; http://dx.doi.org/10.3305%2Fnh.2011.26.2.4998Test