المؤلفون: Galluzzo, C., Pipitone, N., Possemato, N., Crescentini, F., Fautrel, B., Allenbach, Y., Salvarani, C., Benveniste, O.

المصدر: Scientific Abstracts

الإتاحة: https://doi.org/10.1136/annrheumdis-2024-eular.3489Test

المؤلفون: Baroncelli S., Galluzzo C. M., Orlando S., Mphwere R., Kavalo T., Luhanga R., Amici R., Floridia M., Andreotti M., Scarcella P., Marazzi M. C., Giuliano M.

المساهمون: Baroncelli, S, Galluzzo, Cm, Orlando, S, Mphwere, R, Kavalo, T, Luhanga, R, Amici, R, Floridia, M, Andreotti, M, Scarcella, P, Marazzi, Mc, Giuliano, M

مصطلحات موضوعية: infants, Malawi, SARS-CoV-2 antibody prevalence, Settore MED/42 - IGIENE GENERALE E APPLICATA

الوصف: Background: Very limited information is available on SARS-CoV-2 seroprevalence in infants in sub-Saharan countries. Objective: In this study, we aimed to determine the rate and the temporal evolution of SARS CoV-2 seropositivity in breastfed Malawian infants. Study design: Blood samples (n = 250) from 158 infants, born to HIV-negative women and women living with HIV, collected from February 2020 to May 2021, were first tested using an Anti-IgG/A/M SARS CoV 2 ELISA assay against trimeric spike protein, and then, if positive, confirmed using a second ELISA assay detecting IgG against Receptor Binding Domain. Results: The confirmed prevalence of anti-SARS CoV-2 antibodies was 31.0% (95% CI: 23.7%-38.3%) with no significant difference between HIV-exposed and HIV-unexposed infants (29.3% and 37.1% respectively, P = 0.410). The presence of anti-SARS-CoV-2 IgG was not associated with maternal socioeconomic or demographic indices. Conclusions: Our data underline the wide spread of the SARS-CoV-2 infection in the pediatric population in sub-Saharan Africa. Design of more specific serological tests for African samples and improvements in serosurveillance programs are needed for more rigorous monitoring of the dynamics of SARS-CoV-2 infection in Africa.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36128323; info:eu-repo/semantics/altIdentifier/wos/WOS:000865026000001; volume:2; issue:4; firstpage:100110; journal:JOURNAL OF CLINICAL VIROLOGY PLUS; https://hdl.handle.net/2108/329207Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85138556743

الإتاحة: https://doi.org/10.1016/j.jcvp.2022.100110Test
https://hdl.handle.net/2108/329207Test

المؤلفون: Mauro, F. R., Giannarelli, D., Galluzzo, C., Visentin, A., Frustaci, A. M., Sportoletti, P., Vitale, C., Reda, G., Gentile, M., Levato, L., Murru, R., Armiento, D., Ielo, C., Maglione, R., Crisanti, E., Cipiciani, A., Mattiello, V., Gianfelici, V., Barabino, L., Amici, R., Coscia, M., Tedeschi, A., Trentin, L., Baroncelli, S.

المصدر: HemaSphere ; volume 6, page 558-559 ; ISSN 2572-9241

الإتاحة: https://doi.org/10.1097/01.hs9.0000845524.05971.e8Test

المؤلفون: Sandri, G., Belletti, L., Cavedoni, M., Galluzzo, C., Bruni, S., Mascia, M. T.

المصدر: Annals of the Rheumatic Diseases ; volume 80, issue Suppl 1, page 1416.2-1416 ; ISSN 0003-4967 1468-2060

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology, Immunology, Immunology and Allergy, Rheumatology

الوصف: Background: Rare diseases are all those diseases that present, in the European Union, a prevalence of less than 5 cases per 10,000 people. The number of rare diseases is estimated at roughly 7,000 but there are also longstanding medical conditions that elude diagnosis and could be identified as rare. Objectives: Demonstrate the importance of international research in orphan diseases. Methods: We report a case of 44 y/o female patient who arrived to our observation in 2006. Short stature, early puberty, ligament laxity, BMI <17. From the age of 29: recurrent diarrhea, pain in the spine, osteolytic lesions in spine and endosteal thickening in long bones, muscle contractures, strength deficit, muscular hypotrophy and hypotonia, cardiac conduction and blood pressure disorders, demyelinating MS-lesions, hyperprolactinaemia, slow wound healing, sicca syndrome, osteoporosis. No familiarity for bone lesions. In 2007 her first son (21y/o) began to complain pain at limbs. The young man presented the same bone lesions as the mother and shortening of the PR, prolactinoma, recurrent diarrhea, short stature, early puberty. Over the years numerous pathologies have been first hypothesized and then excluded: multiple sclerosis, bone metastases, Paget’s disease, celiac disease, McCune Albright, Camurati-Engelmann syndrome, mitochondrial disease. No conclusive diagnosis despite the thousands of kilometers traveled, the numerous experts heard and the countless examinations carried out by the patients. Results: In September 2009, the patients had been investigated at the NIH (Washington D.C.) during the “Undiagnosed Diseases Program” but without results until 2013 when the patients were informed of the detection of an ATP6V1H gene mutation never described before in humans. The gene encodes a vacuolar ATPase, a multimeric enzyme that plays several roles: is involved in endocytosis, intracellular trafficking, and protein degradation and energy production, appears to be a risk factor in the development of dyslipidemias and type II ...

الإتاحة: https://doi.org/10.1136/annrheumdis-2021-eular.3573Test

المؤلفون: Bucchi L., Mancini S., Zamagni F., Crocetti E., Dal Maso L., Ferretti S., Baldacchini F., Giuliani O., Ravaioli A., Vattiato R., Brustolin A., Candela G., Carone S., Carrozzi G., Cavallo R., Dinaro Y. M., Ferrante M., Iacovacci S., Mazzoleni G., Musolino A., Rizzello R. V., Serraino D., Biggeri A., Stanganelli I., Falcini F., Bella F., Cirilli C., Curatella S., Tumino R., Galluzzo C., Stracci F., Gili A., Ippolito A., Michiara M., Oriente C., Piffer S., Scuderi T., Toffolutti F., Vittadello F.

المساهمون: Bucchi, L., Mancini, S., Zamagni, F., Crocetti, E., Dal Maso, L., Ferretti, S., Baldacchini, F., Giuliani, O., Ravaioli, A., Vattiato, R., Brustolin, A., Candela, G., Carone, S., Carrozzi, G., Cavallo, R., Dinaro, Y. M., Ferrante, M., Iacovacci, S., Mazzoleni, G., Musolino, A., Rizzello, R. V., Serraino, D., Biggeri, A., Stanganelli, I., Falcini, F., Bella, F., Cirilli, C., Curatella, S., Tumino, R., Galluzzo, C., Stracci, F., Gili, A., Ippolito, A., Michiara, M., Oriente, C., Piffer, S., Scuderi, T., Toffolutti, F., Vittadello, F.

الوصف: Background: The global increase in incidence of cutaneous malignant melanoma (CMM) occurring in the past decades has been partly attributed to increased diagnostic scrutiny of early lesions, with a potential phenomenon of overdiagnosis. The reported positive linear relation between skin biopsy rate and incidence of early CMM is compatible with this hypothesis. Objectives: We explored the ecological association between the trends in annual dermatologic office visit rates, skin biopsy rates, incidence rates of in situ and invasive CMM by tumour thickness category, and CMM mortality rates in the Emilia-Romagna Region (northern Italy). Methods: Four cancer registries covering a population of 2,696,000 provided CMM incidence data for the years 2003–2017. Dermatologic office visit rates and skin biopsy rates were calculated using the Regional outpatient care database. All rates were age-standardized. Trends were described with the estimated average annual per cent change (EAAPC). Correlations were tested with the Spearman correlation coefficient. Results: Incidence increased significantly. The increase was steeper for in situ CMM (EAAPC: men, 10.2; women, 6.9) followed by CMM <0.8 mm thick (9.1; 5.2), but the rates grew significantly for most subgroups of CMMs ≥0.8 mm thick. Mortality decreased significantly among women (−2.3) and non-significantly among men. For dermatologic office visit rate and skin biopsy rate the EAAPC were, respectively, 1.7 and 1.8 for men and 1.2 and 0.9 for women. Annual dermatologic office visit rate correlated with skin biopsy rate in both sexes. However, the proportion of skin biopsies out of dermatologic office visits was constant across the years (range: men, 0.182–0.216; women, 0.157–0.191). Conclusions: In Italy, the increasing CMM incidence trend is, at least in part, genuine. Overdiagnosis—if any—is due to an increased patient presentation at dermatologic offices and not to a lower dermatologic threshold to perform biopsy.

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36181283; info:eu-repo/semantics/altIdentifier/wos/WOS:000870309900001; volume:37; issue:2; firstpage:293; lastpage:302; numberofpages:10; journal:JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY; https://hdl.handle.net/11391/1546973Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85140259995

الإتاحة: https://doi.org/10.1111/jdv.18635Test
https://hdl.handle.net/11391/1546973Test

المؤلفون: Baroncelli S., Maria Galluzzo C., Liotta G., Orlando S., Ciccacci F., Andreotti M., Mpwhere R., Luhanga R., Sagno J. B., Amici R., Marazzi M. C., Giuliano M.

المساهمون: Baroncelli, S, Maria Galluzzo, C, Liotta, G, Orlando, S, Ciccacci, F, Andreotti, M, Mpwhere, R, Luhanga, R, Sagno, Jb, Amici, R, Marazzi, Mc, Giuliano, M

مصطلحات موضوعية: Africa, HIV, Hypergammaglobulinemia, IgG subclasse, Pregnancy, Adult, Anti-Retroviral Agent, CD4 Lymphocyte Count, Female, HIV Infection, HIV Seropositivity, Human, Immunoglobulin G, Malawi, Postpartum Period, Young Adult, Settore MED/42 - IGIENE GENERALE E APPLICATA

الوصف: Objectives: Hypergammaglobulinemia and anomalies in the IgG subclass distribution are common in HIV-infected individuals and persist even after many years of antiretroviral therapy (ART). The aim of this study was to investigate the IgG profile and dynamics in pregnant HIV-infected Malawian women in the Option B era.Methods: Thirty-seven treatment-naive women received ART from the third trimester of pregnancy to 6 months post delivery (end of the breastfeeding period). ART continuation (group C) or interruption (group I) was then decided on the basis of the CD4+ cell count at enrolment (>350 or <= 350/mu l). Total IgG and IgG subclasses were determined in maternal serum using a nephelometric assay at baseline and at 6 and 24 months postpartum.Results: At enrolment, 36/37 women had IgG levels >15 g/l and there was a predominance of the IgG1 isotype (more than 90%) in parallel with underrepresentation of IgG2 (5.0%). After 6 months of ART, both groups showed a significant median decrease in total IgG (-3.1 g/l in group I, -3.5 g/l in group C) and in IgG1 (-4.0 g/l and -3.6 g/l, respectively), but only a modest recovery in IgG2 levels (+0.16 in group I, +0.14 g/l in group C). At month 24, hypergammaglobulinemia was still present in 73.7% of women in group C, although a significant reduction was observed in total IgG level and in IgG1 and IgG3 subclasses (p < 0.0001 in all cases). IgG2 levels did not show any significant change. In group I at 24 months, total IgG and IgG subclasses had returned to levels comparable to those at baseline.Conclusions: The beneficial effects of 24 months of ART appear to be limited in the B-cell compartment, with an incomplete reduction of total IgG levels and no recovery of IgG2 depletion. A short ART period did not have significant effects on IgG abnormalities in women who interrupted treatment. (C) 2019 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31499207; info:eu-repo/semantics/altIdentifier/wos/WOS:000493901000001; volume:88; firstpage:1; lastpage:7; numberofpages:7; journal:INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES; http://hdl.handle.net/2108/232593Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85072565373

الإتاحة: https://doi.org/10.1016/j.ijid.2019.09.001Test
http://hdl.handle.net/2108/232593Test

المؤلفون: Floridia M., Masuelli G., Ravizza M., Tassis B., Cetin I., Sansone M., Antoni A. D., Simonazzi G., Maccabruni A., Francisci D., Frisina V., Liuzzi G., Dalzero S., Tamburrini E., Di Lorenzo F., Sterrantino G., Meli M., Campolmi I., Vichi F., Del Pin B., Marocco R., Mastroianni C., S. Mercurio V., Zanaboni D., Guaraldi G., Nardini G., Stentarelli C., Beghetto B., Antoni A. M. D., Molinari A., Crisalli M. P., Donisi A., Piepoli M., Cerri V., Zuccotti G., Giacomet V., Coletto S., Di Nello F., Madia C., Placido G., Milini P., Savalli F., Portelli V., Sabbatini F., Papalini C., Bernini L., Grossi P., Rizzi L., Bernardon M., Maso G., Rizzante E., Belcaro C., Meloni A., Dedoni M., Ortu F., Piano P., Citernesi A., BordoniVicini I., Luzi K., Spinillo A., Roccio M., Vimercati A., Crupano F. M., Calabretti D., Cervi F., Margarito E., Capretti M. G., Marsico C., Faldella G., Martinelli P., Agangi A., Capone A., Maruotti G. M., Tibaldi C., Trentini L., Todros T., Brambilla T., Savasi V., Personeni C., Giaquinto C., Fiscon M., Rubino E., Franceschetti L., Badolato R., Tiso G. C., Genovese O., Cafforio C., Pinnetti C., Casadei A. M., Cavaliere A. F., Cellini M., Marconi A. M., Sacchi V., Ierardi M., Polizzi C., Mattei A., Pirillo M. F., Amici R., Galluzzo C. M., Donnini S., Baroncelli S., Villani P., Cusato M., Cerioli A., De Martino M., Parazzini F., Vella S.

المساهمون: Floridia, M., Masuelli, G., Ravizza, M., Tassis, B., Cetin, I., Sansone, M., Antoni, A. D., Simonazzi, G., Maccabruni, A., Francisci, D., Frisina, V., Liuzzi, G., Dalzero, S., Tamburrini, E., Di Lorenzo, F., Sterrantino, G., Meli, M., Campolmi, I., Vichi, F., Del Pin, B., Marocco, R., Mastroianni, C., S. Mercurio, V., Zanaboni, D., Guaraldi, G., Nardini, G., Stentarelli, C., Beghetto, B., Antoni, A. M. D., Molinari, A., Crisalli, M. P., Donisi, A., Piepoli, M., Cerri, V., Zuccotti, G., Giacomet, V., Coletto, S., Di Nello, F., Madia, C., Placido, G., Milini, P., Savalli, F., Portelli, V., Sabbatini, F., Papalini, C., Bernini, L., Grossi, P., Rizzi, L., Bernardon, M., Maso, G., Rizzante, E., Belcaro, C., Meloni, A., Dedoni, M., Ortu, F., Piano, P., Citernesi, A., Bordonivicini, I., Luzi, K., Spinillo, A., Roccio, M., Vimercati, A., Crupano, F. M., Calabretti, D., Cervi, F., Margarito, E., Capretti, M. G., Marsico, C., Faldella, G., Martinelli, P., Agangi, A., Capone, A., Maruotti, G. M., Tibaldi, C., Trentini, L., Todros, T., Brambilla, T., Savasi, V., Personeni, C., Giaquinto, C., Fiscon, M., Rubino, E., Franceschetti, L., Badolato, R., Tiso, G. C., Genovese, O., Cafforio, C., Pinnetti, C., Casadei, A. M., Cavaliere, A. F., Cellini, M., Marconi, A. M., Sacchi, V., Ierardi, M., Polizzi, C., Mattei, A., Pirillo, M. F., Amici, R., Galluzzo, C. M., Donnini, S.

الوصف: Background: Atazanavir and darunavir represent the main HIV PIs recommended in pregnancy, but comparativedata in pregnant women are limited.We assessed the safety and activity profile of these two drugs in pregnancyusing data from a national observational study.Methods: Women with atazanavir or darunavir exposure in pregnancy were evaluated for laboratory measuresand main pregnancy outcomes (e.g. preterm delivery, low birthweight, non-elective caesarean section and neonatalgestational age-adjusted birthweight Z-score).Results: Final analysis included 500 pregnancies with either atazanavir (n"409) or darunavir (n"91) exposure.No differences in pregnancy outcomes, weight gain in pregnancy, drug discontinuations, undetectable HIV-RNA,haemoglobin, ALT, total cholesterol, HDL cholesterol and LDL cholesterol were observed between the twogroups. At third trimester, exposure to darunavir was associated with higher levels of plasma triglycerides(median 235.5 versus 179 mg/dL; P"0.032) and a higher total cholesterol/HDL cholesterol ratio (median 4.03versus 3.27; P"0.028) and exposure to atazanavir was associated with higher levels of plasma bilirubin (1.54versus 0.32 mg/dL; P<0.001).Conclusions: In this observational study, the two main HIV PIs currently recommended by perinatal guidelinesshowed similar safety and activity in pregnancy, with no evidence of differences between the two drugs in termsof main pregnancy outcomes. Based on the minor differences observed in laboratory measures, prescribingphysicians might prefer either drug in some particular situations where the different impacts of treatment onlipid profile and bilirubin may have clinical relevance.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29244115; info:eu-repo/semantics/altIdentifier/wos/WOS:000429019600026; volume:73; issue:4; firstpage:1025; lastpage:1030; numberofpages:6; journal:JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY; http://hdl.handle.net/11380/1221117Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85044864905

الإتاحة: https://doi.org/10.1093/jac/dkx478Test
http://hdl.handle.net/11380/1221117Test

المؤلفون: Floridia, M, Masuelli, G., Tamburrini, E., Cetin, I., Liuzzi, G., Martinelli, P., Guaraldi, G., Spinillo, A., VIMERCATI, antonella, Maso, G., Pinnetti, C., Frisina, V., Dalzero, S., Ravizza, M., Di Lorenzo, F., Sterrantino, G., Meli, M., Campolmi, I., Vichi, F., Del Pin, B., Marocco, R., Mastroianni, C., Mercurio, V. S., Maccabruni, A., Zaramella, M., Mariani, B., Nardini, G., Stentarelli, C., Beghetto, B., Antoni, A. M. Degli, Molinari, A., Crisalli, M. P., Donisi, A., Piepoli, M., Cerri, V., Zuccotti, G., Giacomet, V., Coletto, S., Di Nello, F., Madia, C., Placido, G., Milini, P., Savalli, F., Portelli, V., Sabbatini, F., Francisci, D., Angeli, G., Bernini, L., Grossi, P., Rizzi, L., Bernardon, M., Rizzante, E., Belcaro, C., Meloni, A., Dedoni, M., Ortu, F., Piano, P., Citernesi, A., Vicini, I. Bordoni, Luzi, K., Roccio, M., MICCOLIS, ANGELICA, DE GENNARO, ALESSANDRA CATERINA, Guerra, B., Cervi, F., Simonazzi, G., Margarito, E., Capretti, M. G., Marsico, C., Faldella, G., Sansone, M., Agangi, A., Capone, A., Maruotti, G. M., Tibaldi, C., Trentini, L., Todros, T., Brambilla, T., Savasi, V., Personeni, C., Giaquinto, C., Fiscon, M., Rubino, E., Franceschetti, L., Tassis, B., Genovese, O., Cafforio, C., Casadei, A. M., Cavaliere, A. F., Cellini, M., Marconi, A. M., Sacchi, V., Ierardi, M., Polizzi, C., Mattei, A., Pirillo, M. F., Amici, R., Galluzzo, C. M., Donnini, S., Baroncelli, S., Cerioli, A., De Martino, M., Parazzini, F., Vella, S.

المساهمون: Floridia, M, Masuelli, G., Tamburrini, E., Cetin, I., Liuzzi, G., Martinelli, P., Guaraldi, G., Spinillo, A., Vimercati, Antonella, Maso, G., Pinnetti, C., Frisina, V., Dalzero, S., Ravizza, M., Di Lorenzo, F., Sterrantino, G., Meli, M., Campolmi, I., Vichi, F., Del Pin, B., Marocco, R., Mastroianni, C., Mercurio, V. S., Maccabruni, A., Zaramella, M., Mariani, B., Nardini, G., Stentarelli, C., Beghetto, B., Antoni, A. M. Degli, Molinari, A., Crisalli, M. P., Donisi, A., Piepoli, M., Cerri, V., Zuccotti, G., Giacomet, V., Coletto, S., Di Nello, F., Madia, C., Placido, G., Milini, P., Savalli, F., Portelli, V., Sabbatini, F., Francisci, D., Angeli, G., Bernini, L., Grossi, P., Rizzi, L., Bernardon, M., Rizzante, E., Belcaro, C., Meloni, A., Dedoni, M., Ortu, F., Piano, P., Citernesi, A., Vicini, I. Bordoni, Luzi, K., Roccio, M., Miccolis, Angelica, DE GENNARO, ALESSANDRA CATERINA, Guerra, B., Cervi, F., Simonazzi, G., Margarito, E., Capretti, M. G., Marsico, C., Faldella, G., Sansone, M., Agangi, A., Capone, A., Maruotti, G. M., Tibaldi, C., Trentini, L., Todros, T., Brambilla, T., Savasi, V., Personeni, C., Giaquinto, C., Fiscon, M., Rubino, E., Franceschetti, L., Tassis, B., Genovese, O., Cafforio, C., Casadei, A. M., Cavaliere, A. F., Cellini, M., Marconi, A. M., Sacchi, V., Ierardi, M., Polizzi, C., Mattei, A., Pirillo, M. F., Amici, R., Galluzzo, C. M., Donnini, S., Baroncelli, S.

مصطلحات موضوعية: Antiretroviral treatment, HIV diagnosi, HIV testing, pregnancy, women's health, Adolescent, Cohort Studie, Female, HIV Infection, Human, Italy, Odds Ratio, Young Adult, Epidemiology, Infectious Diseases

الوصف: Young pregnant women with HIV may be at significant risk of unplanned pregnancy, lower treatment coverage, and other adverse pregnancy outcomes. In a large cohort of pregnant women with HIV in Italy, among 2979 pregnancies followed in 2001-2016, 9.0% were in women <25 years, with a significant increase over time (2001-2005: 7.0%; 2006-2010: 9.1%; 2011-2016: 12.2%, P < 0.001). Younger women had a lower rate of planned pregnancy (23.2% vs. 37.7%, odds ratio (OR) 0.50, 95% confidence interval (CI) 0.36-0.69), were more frequently diagnosed with HIV in pregnancy (46.5% vs. 20.9%, OR 3.29, 95% CI 2.54-4.25), and, if already diagnosed with HIV before pregnancy, were less frequently on antiretroviral treatment at conception (<25 years: 56.3%; ≥25 years: 69.0%, OR 0.58, 95% CI 0.41-0.81). During pregnancy, treatment coverage was almost universal in both age groups (98.5% vs. 99.3%), with no differences in rate of HIV viral suppression at third trimester and adverse pregnancy outcomes. The data show that young women represent a growing proportion of pregnant women with HIV, and are significantly more likely to have unplanned pregnancy, undiagnosed HIV infection, and lower treatment coverage at conception. During pregnancy, antiretroviral treatment, HIV suppression, and pregnancy outcomes are similar compared with older women. Earlier intervention strategies may provide additional benefits in the quality of care for women with HIV.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28712385; info:eu-repo/semantics/altIdentifier/wos/WOS:000409124100021; volume:145; issue:11; firstpage:2360; lastpage:2365; numberofpages:6; journal:EPIDEMIOLOGY AND INFECTION; http://hdl.handle.net/11586/199453Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85026872682; http://journals.cambridge.org/action/displayJournal?jid=HYGTest

الإتاحة: https://doi.org/10.1017/S0950268817001340Test
http://hdl.handle.net/11586/199453Test
http://journals.cambridge.org/action/displayJournal?jid=HYGTest

المؤلفون: Galluzzo C., Chiapparoli I., Corrado A., Cantatore F. P., Salvarani C., Pipitone N.

المساهمون: Galluzzo, C., Chiapparoli, I., Corrado, A., Cantatore, F. P., Salvarani, C., Pipitone, N.

مصطلحات موضوعية: covid-19, eosinophil, graft versus host disease, granuloma, immune check point inhibitor, Myositi, vaccine, viruses

الوصف: Introduction: The idiopathic inflammatory myopathies traditionally comprise dermatomyositis, polymyositis, immune-mediated necrotizing myopathy, anti-synthetase syndrome, and inclusion body myositis. In this review, we aimed to cover the less common forms of generalized myositis. Areas covered: We identified rare forms of widespread myositis on the basis of list provided by the homepage of the Neuromuscular disease center of Washington University, USA and on the basis of the authors’ knowledge. We searched PubMed® and EMBASE® for relevant articles on these forms with the aim of providing as much as possible information on their clinical manifestations as well as guidance on their work-up and treatment. Expert opinion: There is substantial heterogeneity among the various rare forms of generalized myositis in terms of their frequency and characterization. Some forms are reasonably well defined, while others may not represent truly well-defined diseases, but rather variants of other myopathies. The landscape of rare forms appears to have evolved over time, with some forms now being better characterized, while others, such as SARS-Cov-2- and immune checkpoint inhibitor-related myositis have come to the fore only in recent years. Knowledge about rare forms of myositis can aid in their recognition and treatment.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36469633; info:eu-repo/semantics/altIdentifier/wos/WOS:000897061400001; firstpage:1; lastpage:15; numberofpages:15; journal:EXPERT REVIEW OF CLINICAL IMMUNOLOGY; https://hdl.handle.net/11369/427430Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85144108058

الإتاحة: https://doi.org/10.1080/1744666X.2023.2154656Test
https://hdl.handle.net/11369/427430Test

المؤلفون: Galluzzo C., Chiapparoli I., Corrado A., Cantatore F. P., Salvarani C., Pipitone N.

المساهمون: Galluzzo, C., Chiapparoli, I., Corrado, A., Cantatore, F. P., Salvarani, C., Pipitone, N.

مصطلحات موضوعية: eosinophilic myositi, Focal myositi, macrophagic myofasciiti, orbital myositis

الوصف: Introduction: The idiopathic inflammatory myopathies traditionally comprise dermatomyositis, polymyositis, the anti-synthetase syndromes, immune-mediated necrotizing myopathy and inclusion body myositis. However, there are uncommon localized forms that are less known. In this review, we aimed to cover these uncommon forms. Areas covered: We identified rare forms of localized myositis on the basis of list provided by the homepage of the Neuromuscular disease center of Washington University, USA and on the basis of the authors’ knowledge. We searched PubMed® for relevant articles on these forms with the aim of providing as much as possible information on their clinical manifestations as well as guidance on their work-up and treatment. Expert opinion: herein, we provide un updated description of rare forms of localized myositis. These forms are often difficult to diagnose because of their localized nature and are sometimes misdiagnosed as tumors. Knowledge about these rare forms of localized myositis can aid in their recognition and treatment.

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36469645; firstpage:1; lastpage:7; numberofpages:7; journal:EXPERT REVIEW OF CLINICAL IMMUNOLOGY; https://hdl.handle.net/11369/427429Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85144239482

الإتاحة: https://doi.org/10.1080/1744666X.2023.2154655Test
https://hdl.handle.net/11369/427429Test