المؤلفون: REGUERO, MARCELO A., GASPARINI, ZULMA, OLIVERO, EDUARDO B., CORIA, RODOLFO A., FERNÁNDEZ, MARTA S., O´GORMAN, JOSÉ P., GOUIRIC-CAVALLI, SOLEDAD, HOSPITALECHE, CAROLINA ACOSTA, BONA, PAULA, IGLESIAS, ARI, GELFO, JAVIER N., RAFFI, MARÍA E., MOLY, JUAN JOSÉ, SANTILLANA, SERGIO N., CÁRDENAS, MAGALÍ

المصدر: Anais da Academia Brasileira de Ciências. January 2022 94(1)

مصطلحات موضوعية: Antarctic Peninsula, Late Cretaceous, NG Sequence, Snow Hill Island Formation

الوصف: The Snow Hill Island Formation (SHIF; late Campanian – early Maastrichtian) crops out in the northeast of the Antarctic Peninsula and constitutes the basal part of the late Campanian-early Maastrichtian sedimentary succession of the James Ross Basin (NG Sequence). Its major exposures occur at the James Ross and Vega islands. Several fossil-bearing localities have been identified in the SHIF providing a valuable fauna of invertebrates and vertebrates, and flora. Our study focuses on the vertebrate fauna recovered at Gamma and Cape Lamb members of the SHIF. The marine vertebrate assemblages include chondrichthyans, actinopterygians, and marine reptiles (elasmosaurid plesiosaurs and mosasaurs). A diverse terrestrial vertebrate assemblage has been reported being characterized by dinosaurs (sauropod, elasmarian ornithopods, nodosaurid ankylosaur, and a paravian theropod), pterosaurs and birds. Most SHIF dinosaurs share close affinities with penecontemporaneous taxa from southern South America, indicating that at least some continental vertebrates could disperse between southern South America and Antarctica during the Late Cretaceous. The Snow Hill Island Formation provides the most diverse Late Cretaceous marine and continental faunas from Antarctica. The present study summarizes previous and new vertebrate findings with the best actualized stratigraphical framework, providing a more complete fauna association and analyzing further perspectives.

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الوصول الحر: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000201202Test

المؤلفون: Soria, Ignasi Navarro, Fernández, José Manuel García, Saura, Cándido J. Inglés, Fernández, Marta Real

المصدر: Psicologia: Reflexão e Crítica. January 2020 33

مصطلحات موضوعية: Cognitive skills, Mathematics, Language, Learning difficulties, Primary education

الوصف: The aim of the present study was to assess the predictive capacity of several of the most relevant cognitive skills in the academic field that were evaluated using Differential and General Skills Battery(BADyG-E2r). Particular attention was focused on the variables that need to be overcome regarding the curricular objectives related to pass/fail grading as evaluated by the teachers in the instrumental disciplines of Mathematics and Language. The psychometric battery was applied to the 3rd year students in primary education (a total of 512 students) at 4 public schools that were randomly selected in the province of Alicante (Spain). A follow-up of their academic evolution was under taken until the end of primary education. The obtained results show that high scores in Verbal Reasoning, Numerical Reasoning, and Verbal Syllogisms positively and significantly predict academic success at the end of primary education in the subjects of Language and Mathematics.

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الوصول الحر: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-79722020000100204Test

المؤلفون: Fernandez, Marta, Espinosa, Hugo G., Guerra, David, Pena, Ivan, Thiel, David V., Arrinda, Amaia

المصدر: Marta Fernandez, Hugo G. Espinosa, David Guerra, Ivan Pena, David V. Thiel, Amaia Arrinda, RF Energy Absorption in Human Bodies Due to Wearable Antennas in the 2.4 GHz Frequency Band, Bioelectromagnetics, Vol. 41, No. 1, pp. 73-.79, 2020

مصطلحات موضوعية: Electrical Engineering and Systems Science - Signal Processing

الوصف: Human exposure to electromagnetic fields produced by two wearable antennas operating in the 2.4 GHz frequency band was assessed by computational tools. Both antennas were designed to be attached to the skin, but they were intended for different applications. The first antenna was designed for off-body applications, i.e. to communicate with a device placed outside the body, while the second antenna model was optimized to communicate with a device located inside the body. The power absorption in human tissues was determined at several locations of adult male and female body models. The maximum specific absorption rate (SAR) value obtained with the off-body antenna was found on the torso of the woman model and was equal to 0.037 W/kg at 2.45 GHz. SAR levels increased significantly for the antenna transmitting inside the body. In this case, SAR values ranged between 0.23 and 0.45 W/kg at the same body location. The power absorbed in different body tissues and total power absorbed in the body were also calculated; the maximum total power absorbed was equal to 5.2 mW for an antenna input power equal to 10 mW.

الوصول الحر: http://arxiv.org/abs/2402.05700Test

المؤلفون: Fernandez, Marta, Guerra, David, Gil, Unai, Trigo, Inigo, Pena, Ivan, Arrinda, Amaia

المصدر: Marta Fernandez, David Guerra, Unai Gil, Inigo Trigo, Ivan Pena, Amaia Arrinda, Measurements and Analysis of Temporal and Spatial Variability of WiFi Exposure Levels in the 2.4 GHz Frequency Band, Measurement, 149, pp. 1-9, 2020

مصطلحات موضوعية: Electrical Engineering and Systems Science - Signal Processing

الوصف: This paper presents an evaluation of the WiFi exposure levels inside the university in the 2.4 GHz frequency band. The selected environment is the typical scenario where WiFi exposure concerns have increased in the last years, since a Wireless Local Area Network is deployed close to the users. Measurements of 1 h and 24 h of duration were performed to assess the temporal and spatial variability of the signal. Two instruments were employed, a spectrum analyzer appropriate configured for recording accurate and realistic samples and an exposimeter. A detailed description of the equipment, the measurement procedure and data analysis is provided in order to allow the reproducibility of these types of measurements. Finally, a comparison of the WiFi levels obtained by other authors is presented, concluding that all these methods are useful for determining WiFi exposure distribution, but if more accurate results are required, professional equipment appropriately configured should be used.
Comment: 9 pages

الوصول الحر: http://arxiv.org/abs/2402.05083Test

المؤلفون: Santos, Camila dos, Siman, Maíra, Fernández, Marta

المصدر: Brazilian Political Science Review. January 2019 13(1)

مصطلحات موضوعية: Brazil, South-South cooperation narratives, postcolonial theory, identity, ambivalences, Africa, Angola

الوصف: Adopting a postcolonial perspective, this article approaches Brazilian South-South cooperation ‘narratives’ in Africa as part of a politics of identity that helps redefine Brazil’s place in the modern world. The article discusses how South-South cooperation operates as a site of knowledge and power through which a developmentalist Brazilian identity is reproduced and subalternity can be constantly renegotiated. Through a brief analysis of the narratives of Brazilian involvement in Angola, it emphasizes how the production of the state self is also permeated by several ambivalences that update colonial tropes and bring new forms of subjugation. If, on the one hand, the movement undertaken in the article permits discussing the very ambiguity of the postcolonial condition – mainly by exposing the tensions and indeterminacies that permeate Brazil’s engagements in the global arena – on the other hand, it opens up new theoretical avenues for analyzing Brazilian foreign policy.

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الوصول الحر: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1981-38212019000100206Test

المؤلفون: Almenara Fernández, Marta

المساهمون: University/Department: Universitat Autònoma de Barcelona. Departament de Cirurgia

مرشدي الرسالة: Lamas Gómez, Claudia Mariana

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Osteosarcoma, Adults, Adultos, Pronòstic, Pronóstico, Prognostic, Ciències de la Salut

الوصف: El osteosarcoma es un tumor maligno del esqueleto caracterizado por la formación directa de hueso inmaduro o tejido osteoide por las células tumorales. Representa el 0.2% de todos los tumores malignos y el 15-20% de las neoplasias primarias de hueso, constituyendo el segundo tumor óseo primario maligno en frecuencia, tras el mieloma múltiple. La incidencia estimada del osteosarcoma es de 3 casos/millón de población/año. La mayoría de osteosarcomas primarios de alto grado aparecen en la segunda década de la vida, pero existe un segundo pico significativo de incidencia la sexta y séptima décadas, donde es de 1.5 casos/millón de población/año. La edad del paciente en el momento del diagnóstico del osteosarcoma está incrementando; sin embargo, las características tumorales en pacientes con edad igual o superior a 40 años no están tan establecidas como en el paciente adolescente o adulto joven. Es conocido que la proporción de osteosarcomas en este grupo de edad es del 13-30% de la totalidad de los osteosarcomas, y que estos tumores suelen ser secundarios a la enfermedad de Paget, radiación o condrosarcomas desdiferenciados. Se han revisado los osteosarcomas en pacientes con edad igual o superior a 40 años, diagnosticados y tratados en la Unidad de Cirugía Ortopédica Oncológica del Hospital de la Santa Creu i Sant Pau, en el periodo comprendido entre los años 1986-2016. Se han recogido datos epidemiológicos, clínicos, radiológicos y analíticos, así como del tratamiento empleado y su evolución. Se ha procedido a realizar una comparación de los datos obtenidos con la literatura publicada y con un grupo de pacientes diagnosticados de osteosarcoma y edad inferior a 40 años, tratados durante el mismo periodo. La muestra está formada por 37 pacientes, con una edad media de 52 años (40-89 años). Respecto al osteosarcoma de aparición en edades más tempranas, presenta una mayor predilección por la localización pélvica, un mayor porcentaje de patrones radiológicos osteolíticos, un mayor número de osteosarcomas secundarios y subtipos histológicos fibroblásticos. El número de ciclos empleado en el tratamiento quimioterápico es menor, así como el porcentaje de cirugía de salvamento de extremidad y la tasa de infección y fracaso mecánico tras la cirugía. El estadio inicial de la enfermedad, la recidiva y la diseminación tumoral son similares. Los factores pronósticos de supervivencia global (SG) del osteosarcoma son: el estadio de la enfermedad en el momento del diagnóstico del osteosarcoma y la diseminación tumoral, siendo la SG a 5 años del 62.2% y del 57% a 10 años. Los factores pronósticos de supervivencia libre de evento (SLE) son: el estadio de la enfermedad en el momento inicial, la recidiva local y la diseminación tumoral, siendo la SLE a 5 años del 52.2% y del 42.5% a 10 años. La frecuencia de cirugía de salvamento de extremidad es del 59.4%, y la frecuencia de amputación global (primaria y secundaria) es del 40.6%. La frecuencia de recidiva local es del 32.4%, y la de diseminación a distancia de la enfermedad es del 43.2%. La presencia de antecedentes personales o familiares oncológicos, el tabaquismo y la existencia de un antecedente traumático sobre la región donde asienta el tumor no se correlacionan de forma signifivativa con la aparición de un osteosarcoma.

الوصف (مترجم): Osteosarcoma is a malignant skeletal tumor from the direct formation of immature bone or osteoid tissue by tumor cells. It represents 0.2% of all malignant tumors and 15-20% of primary neoplasms of bone, constituting the second malignant primary bone tumor in frequency, after multiple myeloma. The estimated incidence of osteosarcoma is 3 cases/million population/year. Most cases of osteosarcomas appear in the second decade of life, but there is also a second significant peak of incidence in the sixth and seventh decade, where it is 1.5 cases/million population/year. The age of the patient at the time of diagnosis of osteosarcoma is increasing; however, the tumoral characteristics in patients with age equal or greater than 40 years are not as established as in the adolescent or young adult patient. It is known that the proportion of osteosarcomas in this age group is 13-30% of all osteosarcomas, and these are found in Paget's disease, radiation or dedifferentiated chondrosarcomas. Osteosarcomas have been reviewed in patients with age equal or greater than 40 years, diagnoses and procedures in the Orthopedic Surgery Unit of the Hospital de la Santa Creu i Sant Pau, in the period between 1986-2016. Epidemiological, clinical, radiological and analytical data have been collected, as well as the treatment used and disease’s evolution. We proceeded to make a comparison of the data corresponding to the published literature and to the group of patients diagnosed with osteosarcoma under 40 years, during the same period and hospital. The sample consists of 37 patients, with an average age of 52 years (40-89 years). Respect to osteosarcoma in the earliest ages, there is a predilection of the pelvic location, a greater percentage of osteolytic radiological patterns, a greater number of secondary osteosarcomas and fibroblastic histological subtypes. The number of cycles used in chemotherapy treatment is lower, as well as the percentage of limb salvage surgery and the rate of infection and mechanical failure after surgery. The initial stage of the disease, recurrence and tumoral dissemination are similar in both groups. Prognostic factors to the overall survival (OS) of osteosarcoma are: the stage of the disease at the time of diagnosis of osteosarcoma and tumoral dissemination, with the OS at 5 years of 62.2% and 57% at 10 years. Prognostic factors to event-free survival (SLE) are: the stage of the disease at the initial moment, the local recurrence and the tumoral dissemination, being the SLE at 5 years of 52.2% and 42.5% at 10 years. The frequency of limb salvage surgery is 59.4%, and the frequency of the amputation (primary and secondary) is 40.6%. The frequency of local recurrence is 32.4%, and the tumoral dissemination is 43.2%. The presence of personal or family history of cancer, smoking and the existence of a traumatic history in the region where the tumor is found does not correlate significantly with the appearance of an osteosarcoma.

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/666747Test

المؤلفون: Santiago, Vinícius, Fernández, Marta

المصدر: Contexto Internacional. April 2017 39(1)

مصطلحات موضوعية: War, Favelas, State, Mothers, Temporality

الوصف: This article analyses the political status of mothers whose children have been killed by members of the Brazilian military police and armed forces in the favelas of Rio de Janeiro in the course of the ‘war against drugs’. These mothers bear witness to the reality of state interference in the lives of their families. The loss of a child interrupts their intimate affective bonds and temporal linkages between the past, present and future, thereby requiring a resignification of the meaning and temporality of their lives. The war waged by the state and the mothers’ struggle for justice gives rise to a social dynamic that positions these mothers in a reordering of space and a redefinition of time, creating a spatio-temporal existence of pain, despair and hope.

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الوصول الحر: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-85292017000100035Test

المؤلفون: Dinarès Fernández, Marta

المساهمون: University/Department: Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals

مرشدي الرسالة: Saurí i Pujol, David, Rovira i Val, MªRosa

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Metabolisme urbà, Metabolismo urbano, Urban metabolism, Anàlisi de flux de substàncies, Análisis del flujo de sustancias, Substance flow analysis, Marroc, Marruecos, Morocco, Ciències Experimentals

الوصف: Por primera vez en la historia de la humanidad, una mayor proporción de la población global vive en áreas urbanas. En las próximas décadas, se espera que la mayor parte del crecimiento mundial previsto sea absorbido por las zonas urbanas costaneras del mundo en desarrollo, específicamente en las ciudades pequeñas y medianas así como en las zonas periféricas. En las últimas décadas, tanto las actividades humanas de producción y consumo de alimentos, cómo el fenómeno de la urbanización, se han identificado como actividades que contribuyen a alterar los ciclos naturales de los nutrientes del nitrógeno (N) y del fósforo (P), así como de promover el agotamiento de los recursos minerales del fósforo, generando impactos medioambientales negativos resultantes de la acumulación y pérdida de nutrientes en la tierra, el agua y en la atmosfera. Ambos macronutrientes son básicos para la seguridad alimentaria regional y global al ser insumos esenciales para la producción agrícola de los alimentos. En un mundo cada vez más urbanizado, tanto las áreas urbanas como su desarrollo se encuentan en el centro de todas las discusiones sobre sostenibilidad y desarrollo sostenible. Sin embargo, el papel que desempeñan las ciudades como motores de cambio ambiental a múltiples escalas, p.ej. como agentes en el flujo de energía y materiales, permanece poco reconocido, y por lo tanto poco estudiado, siendo aún más escasos los estudios sobre ciudades en los países en desarrollo, debido a su limitada disponibilidad, acceso y recolección de datos. La noción de metabolismo urbano (UM) proporciona un marco conceptual para el estudio del funcionamiento de las ciudades, y consecuentemente, una aproximación al análisis de la sostenibilidad de las mismas. La presente investigación, centrada en el caso de estudio de la ciudad-región de Gran Nador, en el noreste de Marruecos, tiene por objetivo el estudio del papel que desempeñan las áreas urbanas como agentes en el metabolismo de los alimentos. El estudio, por un lado, analiza la circulación de los principales flujos de nutrientes de los alimentos, el nitrógeno (N) y el fósforo (P), mediante la aplicación del método de Análisis del Flujo de Sustancias (SFA). Por otro lado, contextualiza el desarrollo sociopolítico e histórico de la región urbana de estudio. Los flujos de N y P se calcularon mediante el uso,principalmente, de datos procedentes de bases de datos estadísticas oficiales, literatura publicada e informes no publicados elaborados por las instituciones municipales y regionales de la zona. Además, se utilizaron distintas aproximaciones y “proxies”, así como la adopción de diferentes supuestos y métodos de estimación. Finalmente, se realizó un análisis de incertidumbre para mejorar la fiabilidad de los resultados. Los resultados muestran la linealidad de los flujos de N y P analizados, evidenciando así la apertura del metabolismo de los alimentos en el sistema urbano de Gran Nador. Los resultados también sugieren los fuertes indicios en relación a la influencia significativa que las historias urbanas, es decir, el contexto sociopolítico e histórico en que se desarrolla una región o área urbana, tienen sobre la estructura, el funcionamiento y los flujos metabólicos de la misma área urbana. Posteriormente, el estudio presenta distintas opciones existentes hacia una gestión más equilibrada de los nutrientes, a la vez que para reducir la pérdida y acumulación y aumentar la recirculación de los nutrientes de N y P en Gran Nador. Finalmente, el estudio introduce posibles nuevas líneas de investigación para avanzar con el presente estudio.

الوصف (مترجم): For the first time in history a majority of the global population live in urban areas. In the coming decades, most of the world’s population growth is expected to be absorbed by coastal urban areas -specifically in small and medium cities and urban peripheries- of the developing world. In the last decades, anthropogenic food-related activities and urbanization have been identified to contribute altering the natural nitrogen (N) and phosphorus (P) nutrient cycles, as well as exhausting P-mineral resources. These alterations have caused a myriad of pollution and environmental problems resulting from nutrient accumulation and loss to the soil, waters and air. Both macronutrients are critical for regional and global food security, by virtue of being essential inputs for agricultural food production. In an increasingly urbanized world, urban areas and their development are at the centre of all discussions on sustainability and/or sustainable development. Yet, the role played by cities as drivers of environmental change at multiple scales, e.g. as agents in the flow of energy and materials, stays poorly recognized, and thus grossly understudied, remaining even more scarce (even least available) when it comes to studies of cities in developing countries. The latter are significantly constrained by limited data availability, access, and data collection resources. The notion of Urban Metabolism (UM) provides a conceptual framework to study how a city functions, and hence, a way to address the sustainability of a city. The present research, focused in the city-region of Grand Nador in northeast Morocco as a case study, aimed to study the role played by urban areas as agents in the metabolism of food by, on the one hand, examining the circulation of the major nitrogen (N) and phosphorus (P) food-related flows by using the analytical method of Substance Flow Analysis (SFA), and on the other hand, contextualizing the politico-historical development of the urban region. N and P flows were estimated using mainly data from official statistical databases, published literature and unpublished reports authored by municipal and regional level institutions. Besides, approximations, surrogates and proxies were used, as well as the adoption of different assumptions and estimation methods. As a result of data limitations, an uncertainty analysis was performed to enhance the reliability of results. The results displayed the linearity of the N and P food-related flows studied, elucidating the openness of the food metabolism in the urban system of Grand Nador. Results also showed the strong insights of the significant influence that urban histories, namely the sociopolitical and historical context in which a region develops, have on its structure, functioning and metabolic flows. Different existing options towards more-balanced nutrient management and to reduce and enhance nutrient N and P recirculation in Grand Nador are discussed. Likewise, new lines of further research are advanced.

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/399282Test

المؤلفون: Fernández, Marta

المصدر: Contexto Internacional. December 2014 36(2)

مصطلحات موضوعية: Kant, Iluminismo, Cosmopolitismo, Eurocentrismo, Racismo

الوصف: Desde o fim da Guerra Fria, as teorias liberais das Relações Internacionais e os discursos das Nações Unidas vêm evocando a autoridade de Immanuel Kant e o seu famoso tratado A paz perpétua para avançar a ideia acerca da conexão entre a paz e as democracias liberais. O artigo visa oferecer uma leitura alternativa de Kant, vis-à-vis a literatura mainstream das Relações Internacionais, chamando a atenção para os limites e ambiguidades do suposto cosmopolitismo kantiano ao resgatar os rastros racistas e excludentes da sua filosofia.

وصف الملف: text/html

الوصول الحر: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-85292014000200417Test

المؤلفون: Granero Fernández, Marta

مرشدي الرسالة: López Jornet, María Pía, Universidad de Murcia. Departamento de Dermatología, Estomatología, Radiología y Medicina Física

المصدر: TDR (Tesis Doctorales en Red)

مصطلحات موضوعية: Boca, Enfermedades, Ciencias de la salud

الوقت: 616.3

الوصف: Introducción El diagnóstico precoz en el cáncer oral es un objetivo prioritario de salud pública, en el cual los profesionales de la salud oral deben desempeñar un papel protagonista. La leucoplasia es la lesión potencialmente maligna más frecuente y la que presenta mayor índice de transformación a carcinoma de células escamosas. Objetivos Analizar las variables clínicas e histológicas de los pacientes con leucoplasia oral. Conocer los factores de riesgo asociados a la leucoplasia oral.Evaluar la bioquímica sanguínea en pacientes con leucoplasia oral comparándolos con la bioquímica sanguínea del grupo control.Valorar el análisis histomorfométrico de los pacientes que presentan leucoplasia oral en la encía.Evaluar el índice de transformación maligna de la leucoplasia oral. Material y métodos Para recopilar los datos hemos realizado un estudio clínico-patológico retrospectivo basado en los expedientes clínicos diagnosticados de leucoplasiaoral y confirmados histopatológicamente en la Unidad Docente de Medicina Oral de la Universidad de Murcia. Se tomaron los datos marcados en el protocolo, y se examinaron los informes anatomopatológicos. Nuestra muestra estaba compuesta por 142 pacientes, de los cuales había 63 mujeres y 79 hombres. Los datos registrados son todos las variables sociodemográficas, las características de la leucoplasia oral (ubicación, tamaño, localización), los hábitos de consumo, la bioquímica sanguínea (colesterol, LDL, HDL y glucosa) y datoshistopatológicos; se estudió su influencia como factores de riesgo de la leucoplasia oral. También se realizó un estudio morfométrico de las leucoplasias ubicadas en la encía. Resultados - Ser fumador aumenta la probabilidad de sufrir leucoplasia oral (p=0,004; OR= 11,54). - Niveles elevados de glucosa aumentan la probabilidad de presentar leucoplasia oral(p=0,026; OR=6,42), - La forma clínica no homogénea (p=0,039; OR=9,06)y ser fumador (p=0,044; OR=28,33) favorece la aparición de displasia oral. - El índice de transformación maligna de la leucoplasia oral en la muestra de individuos de la Región de Murcia de nuestro estudio es de 3,5%. Conclusión En la leucoplasia oral es muy importante conocer los factores de riesgo que favorecen su aparición puesto que estamos hablando de un desorden potencialmente maligno, si conseguimos reducir la prevalencia de la leucoplasia oral reduciremos los casos de cáncer oral. I

الوصف (مترجم): Introduction Early diagnosis of oral cancer is a public health priority in which oral health professionals should play a leading role. Leukoplakia is the most common potentially-malignant lesion and has the highest rate of transformation into squamous cellcarcinoma. Objectives To analyse the clinical and histological variables of patients diagnosed with oral leukoplakia. To understand the risk factors associated with oral leukoplakia. To evaluate blood biochemistry in patients diagnosed with oral leukoplakia in comparison with the control group’s blood biochemistry. To assess the histomorphometric analysis of patients diagnosed with oral leukoplakia in the gum. To evaluate the rate of malignant transformation of oral leukoplakia. Material and methods A retrospective clinical-pathological study based on medical records diagnosed with oral leukoplakia and histopathologically confirmed until 2010 at the Teaching Unit of Oral Medicine of the University of Murcia has been performed in order to collect a significant amount of data. Data defined in the protocol were taken and anatomopathological hard-copy reports were examined. The sample was composed of 142 patients, of whom 63 were women and 79 men. The recorded data corresponds to the socio-demographic variables, characteristics of oral leukoplakia (size and location), consumption habits, blood chemistry (cholesterol, LDL, HDL and glucose) and histopathological data; the influence of these variables as risk factors for oral leukoplakia and oral dysplasia was studied. A morphometric study of leukoplakia located in the gum was also carried out. Results - Smoking increases the likelihood of oral leukoplakia (p = 0.004; OR = 11.54). - Diabetes increases the probability of oral leukoplakia (p = 0.026; OR = 6.42), - Non-homogeneous clinical form (p = 0.039; OR = 9.06) plus smoking (p = 0.044; OR = 28.33) favour the appearance of oral dysplasia. - The rate of malignant transformation of oral leukoplakia in the considered sample of individuals from the Region of Murcia under study is 3.5%. Conclusions It is essential to identify the risk factors that favour the appearance of oral leukoplakia since it is a potentially malignant disorder; by reducing the prevalence of oral leukoplakia, the cases of oral cancer will therefore be reduced.

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/311630Test