المؤلفون: Kouby, F., Chanal, J., Jafari, A., Ermisch, C., Farhi, D., Aractingi, S., Avril, M.-F.

المصدر: Annales de Dermatologie et de Vénéréologie ; volume 147, issue 4, page 265-270 ; ISSN 0151-9638

مصطلحات موضوعية: Dermatology

الإتاحة: https://doi.org/10.1016/j.annder.2019.01.028Test
https://api.elsevier.com/content/article/PII:S0151963820300624?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0151963820300624?httpAccept=text/plainTest

المؤلفون: Grange, P. A., Gressier, L., Dion, P. L., Farhi, D., Benhaddou, N., Gerhardt, P., Morini, J. P., Deleuze, J., Pantoja, C., Bianchi, A., Lassau, F., Avril, M. F., Janier, M., Dupin, N.

المصدر: Journal of Clinical Microbiology ; volume 50, issue 3, page 546-552 ; ISSN 0095-1137 1098-660X

الوصف: Syphilis diagnosis is based on clinical observation, serological analysis, and dark-field microscopy (DFM) detection of Treponema pallidum subsp. pallidum , the etiological agent of syphilis, in skin ulcers. We performed a nested PCR (nPCR) assay specifically amplifying the tpp47 gene of T. pallidum from swab and blood specimens. We studied a cohort of 294 patients with suspected syphilis and 35 healthy volunteers. Eighty-seven of the 294 patients had primary syphilis, 103 had secondary syphilis, 40 had latent syphilis, and 64 were found not to have syphilis. The T. pallidum nPCR results for swab specimens were highly concordant with syphilis diagnosis, with a sensitivity of 82% and a specificity of 95%. Reasonable agreement was observed between the results obtained with the nPCR and DFM methods (kappa = 0.53). No agreement was found between the nPCR detection of T. pallidum in blood and the diagnosis of syphilis, with sensitivities of 29, 18, 14.7, and 24% and specificities of 96, 92, 93, and 97% for peripheral blood mononuclear cell (PBMC), plasma, serum, and whole-blood fractions, respectively. HIV status did not affect the frequency of T. pallidum detection in any of the specimens tested. Swab specimens from mucosal or skin lesions seemed to be more useful than blood for the efficient detection of the T. pallidum genome and, thus, for the diagnosis of syphilis.

الإتاحة: https://doi.org/10.1128/jcm.00702-11Test

المؤلفون: Jarzebowski, W, Piketty, C, de Truchis, P, Caumes, E, Farhi, D, Lascaux, AS, Bouldouyre, MA, Derradji, O, Pacanowski, J, Dupin, N, Costagliola, D, Grabar, S

المصدر: Journal of the International AIDS Society ; volume 13, issue S4 ; ISSN 1758-2652 1758-2652

الوصف: 7‐11 November 2010, Tenth International Congress on Drug Therapy in HIV Infection, Glasgow, UK

الإتاحة: https://doi.org/10.1186/1758-2652-13-s4-p223Test

المؤلفون: Farhi, D.

المصدر: Rencontre Chrétiens et Juifs. 8 (1974) 19-22

مصطلحات موضوعية: Berit milah -- Biblical teaching

الوصول الحر: https://uli.nli.org.il/discovery/search?query=issn,exact,0223-5579&tab=LibraryCatalog&search_scope=MyInstitution&vid=972NNL_ULI_C:MAINTest

المؤلفون: Bruno, M., Donay, J.L., Resche-Rigon, M., Tristan, A., Farhi, D., Mercier-Delarue, S., Cavelier-Balloy, B., Assouly, P., Petit, A., Bagot, M., Reygagne, P.

المصدر: Annales de Dermatologie et de Vénéréologie ; volume 145, issue 12, page S124-S125 ; ISSN 0151-9638

مصطلحات موضوعية: Dermatology

الإتاحة: https://doi.org/10.1016/j.annder.2018.09.139Test
https://api.elsevier.com/content/article/PII:S0151963818306926?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0151963818306926?httpAccept=text/plainTest

المؤلفون: Auffret, N., Claudel, J.‐P., Leccia, M.‐T., Poli, F., Farhi, D., Dréno, B.

المساهمون: Galderma International, France

المصدر: Journal of the European Academy of Dermatology and Venereology ; volume 30, issue 5, page 824-828 ; ISSN 0926-9959 1468-3083

الوصف: Background Acne is a concern in adults, especially in women. The specifications in current acne grading systems are not applicable to this particular population. Objective To develop and validate a measurement tool ( AFAST : adult female acne scoring tool) for acne in women by taking into account the specific locations of adult female acne, and to evaluate the impact of the photographic modalities on rating reproducibility. Methods Six experts in dermatology rated pictures of 54 women with a phototype from I to IV during two sessions, with an interval of 24 h. They rated the acne severity on the face using the GEA scale (Score 1) together with a new scale to assess acne on the mandibular zone (Score 2). Pictures of 30 women were taken using a standardized photographic device; pictures of the other 24 women were taken by their own dermatologists during daily practice. Results At session 1, the inter‐rater's reproducibility was good for Score 1 with an ICC of 0.77 [0.72–0.83], and excellent for Score 2 with an ICC of 0.87 [0.82–0.91]. Between sessions 1 and 2, the mean intra‐rater's reproducibility was excellent for both scores with an ICC of 0.88 [0.84–0.92] for Score 1, and an ICC of 0.87 [0.78–0.92] for Score 2. Photographic modalities had no significant effect on the inter‐ and intra‐rater's reproducibility. Conclusion For the first time, it has been demonstrated that AFAST can accurately rate acne severity in women. It is a promising, easy‐to‐use tool for both daily practice and clinical investigation.

الإتاحة: https://doi.org/10.1111/jdv.13518Test

المؤلفون: Farhi, D., Gerhardt, P., Dupin, N.

المصدر: Les infections sexuellement transmissibles ; page 152-156

الإتاحة: https://doi.org/10.1016/b978-2-294-08874-2.00026-8Test

المؤلفون: Chanal, J., Jafari, A., Ermisch, C., Farhi, D., Bui, P., Batchvarova, Z., Kalampokas, A., Carlotti, A., Avril, M.-F.

المصدر: Annales de Dermatologie et de Vénéréologie ; volume 141, issue 6-7, page S34-S35 ; ISSN 0151-9638

مصطلحات موضوعية: Dermatology

الإتاحة: https://doi.org/10.1016/j.annder.2014.04.055Test
https://api.elsevier.com/content/article/PII:S0151963814002105?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0151963814002105?httpAccept=text/plainTest

المؤلفون: Farhi, D., Bouadjar, B.

المصدر: Annales de Dermatologie et de Vénéréologie ; volume 140, issue 5, page 387-389 ; ISSN 0151-9638

مصطلحات موضوعية: Dermatology

الإتاحة: https://doi.org/10.1016/j.annder.2013.02.020Test
https://api.elsevier.com/content/article/PII:S0151963813005504?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0151963813005504?httpAccept=text/plainTest

المؤلفون: Régnier-Rosencher, E., Farhi, D., Lebrun, A., Salliot, C., Dougados, M., Dupin, N.

المصدر: Dermatology ; volume 224, issue 1, page 72-83 ; ISSN 1018-8665 1421-9832

مصطلحات موضوعية: Dermatology

الوصف: Background: The incidence of severe infections is increased under biologic therapies and the skin is the second localization. Objective: To appraise the factors associated with severe skin infections (SSI) in patients under biologic therapies for inflammatory rheumatic diseases (IRD). Methods: We performed a case-control (ratio 1:3) study nested in a prospective cohort of patients with IRD. SSI was defined as requiring hospitalization or intravenous anti-infectious therapy. We defined two imbedded periods: period A was the time window between the first biologic therapy and the SSI; period B was the last 3 or 12 months (for tumor necrosis factor blockers or rituximab, respectively) before the SSI. Results: Among 4,361 patients with IRD, 29 had a SSI under biologic therapy. In multivariate analyses, SSI were significantly associated with smoking, baseline C-reactive protein and gammaglobulinemia, non-steroidal anti-inflammatory drugs before biologic therapy, cumulative dose of steroids, concomitant steroids during period A, number of different biologic therapies during period A, treatment with infliximab during period A, period B or as first biologic therapy and treatment at high dose during period B. Conclusion: In patients under biologic therapies for IRD, the risk of SSI is associated with several factors including tobacco, treatment with infliximab or high dose range.

الإتاحة: https://doi.org/10.1159/000337422Test
https://www.karger.com/Article/Pdf/337422Test