المؤلفون: Binbin Gu, Anwei Hou, Jeroen S. Dickschat

المصدر: Beilstein Journal of Organic Chemistry, Vol 18, Iss 1, Pp 818-824 (2022)

مصطلحات موضوعية: biosynthesis, enantioselective synthesis, enzyme mechanisms, gas chromatography, terpenoids, Science, Organic chemistry, QD241-441

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1860-5397Test

الوصول الحر: https://doaj.org/article/3db49b027d0c4ea2af3caaadd38ad04bTest

المؤلفون: Stoffel, Gabriele MM, Saez, David Adrian, DeMirci, Hasan, Vögeli, Bastian, Rao, Yashas, Zarzycki, Jan, Yoshikuni, Yasuo, Wakatsuki, Soichi, Vöhringer-Martinez, Esteban, Erb, Tobias J

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 116(28)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Amino Acids, Carbon Dioxide, Carrier Proteins, Catalysis, Catalytic Domain, Enzymes, Fatty Acid Desaturases, Models, Molecular, Streptomycetaceae, carboxylases, enzyme mechanisms, carbon dioxide, CO2 fixation, RuBisCO

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4010m3wjTest

المؤلفون: Heidi Klem, Juan V. Alegre-Requena, Robert S. Paton

مصطلحات موضوعية: Biophysics, Biochemistry, Computational Biology, Chemical Sciences not elsewhere classified, val51 dihedral flip, studied enzyme mechanisms, second active site, oxyanion strand relative, multistep reaction leading, crystallized structures representing, corresponding energy profile, competent oxyanion hole, atomistic changes required, allosterically active conformations, 25 å away, state kinetic studies, glutamine turnover number, inactive igps conformation, igps allosteric mechanism, proposed mechanism, many studies, hydrolyzes glutamine, glutamine amidotransferase, allosteric communication, allosteric activation, igps based, ∼ 4500, thioester formation, subsequent investigations, results reveal

العلاقة: https://figshare.com/articles/journal_contribution/Catalytic_Effects_of_Active_Site_Conformational_Change_in_the_Allosteric_Activation_of_Imidazole_Glycerol_Phosphate_Synthase/24751708Test

الإتاحة: https://doi.org/10.1021/acscatal.3c04176.s001Test
https://figshare.com/articles/journal_contribution/Catalytic_Effects_of_Active_Site_Conformational_Change_in_the_Allosteric_Activation_of_Imidazole_Glycerol_Phosphate_Synthase/24751708Test

المؤلفون: Sridhar, S. (Shruthi), Zavarise, A. (Alberto), Kiema, T.-R. (Tiila-Riikka), Dalwani, S. (Subhadra), Eriksson, T. (Tor), Hajee, Y. (Yannick), Enugala, T. R. (Thilak Reddy), Wierenga, R. K. (Rik K.), Widersten, M. (Mikael)

مصطلحات موضوعية: FucO, aldehyde reductase, directed evolution, enzyme functions, enzyme mechanisms, substrate selectivity

وصف الملف: application/pdf

الإتاحة: http://urn.fi/urn:nbn:fi-fe20230919132255Test

المؤلفون: Rahman, M. T. (M. Tanvir), Koski, M. K. (M. Kristian), Panecka-Hofman, J. (Joanna), Schmitz, W. (Werner), Kastaniotis, A. J. (Alexander J.), Wade, R. C. (Rebecca C.), Wierenga, R. K. (Rik K.), Hiltunen, J. K. (J. Kalervo), Autio, K. J. (Kaija J.)

مصطلحات موضوعية: Enzyme mechanisms, Fatty acids, Protein design, Respiration, X-ray crystallography

وصف الملف: application/pdf

الإتاحة: http://urn.fi/urn:nbn:fi-fe2023071390600Test

المؤلفون: Höpfner, Dorothea, Cichy, Adam, Pogenberg, Vivian, Krisp, Christoph, Mezouar, Soraya, Bach, Nina, C, Grotheer, Jan, Zarza, Sandra, Madariaga, Martinez, Eric, Bonazzi, Matteo, Feige, Matthias, J, Sieber, Stephan, A, Schlüter, Hartmut, Itzen, Aymelt

المساهمون: Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf (UKE), Martinistraße 52, 20246, Hamburg, Germany., Center for Integrated Protein Science Munich (CIPSM), Department Chemistry, Group of Proteinchemistry, Technical University of Munich, Lichtenbergstraße 4, 85747, Garching, Germany., Institute of Clinical Chemistry and Laboratory Medicine, Section Mass Spectrometry and Proteomics, University Medical Center Hamburg-Eppendorf (UKE), Martinistraße 52, 20246, Hamburg, Germany., Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Technische Universität Munchen - Technical University Munich - Université Technique de Munich (TUM), Institut universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Institut de Recherche en Infectiologie de Montpellier (IRIM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf (UKE), Martinistraße 52, 20246, Hamburg, Germany

المصدر: ISSN: 2399-3642 ; Communications Biology ; https://amu.hal.science/hal-04537727Test ; Communications Biology, 2023, 6 (1), pp.1124. ⟨10.1038/s42003-023-05494-7⟩.

مصطلحات موضوعية: Bacterial toxins, Enzyme mechanisms, Nucleotide-binding proteins, X-ray crystallography, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology

العلاقة: hal-04537727; https://amu.hal.science/hal-04537727Test; https://amu.hal.science/hal-04537727/documentTest; https://amu.hal.science/hal-04537727/file/42003_2023_Article_5494.pdfTest

الإتاحة: https://doi.org/10.1038/s42003-023-05494-7Test
https://amu.hal.science/hal-04537727Test
https://amu.hal.science/hal-04537727/documentTest
https://amu.hal.science/hal-04537727/file/42003_2023_Article_5494.pdfTest

المؤلفون: Pitsawong, Warintra, Pádua, Ricardo A P, Grant, Timothy, Hoemberger, Marc, Otten, Renee, Bradshaw, Niels, Grigorieff, Nikolaus, Kern, Dorothee

المساهمون: RNA Therapeutics Institute

المصدر: Nature ; 616 ; 7955 ; 183 ; 189 ; England

مصطلحات موضوعية: Enzyme mechanisms, Structural biology

العلاقة: Nature; https://doi.org/10.1038/s41586-023-05836-9Test; Pitsawong W, Pádua RAP, Grant T, Hoemberger M, Otten R, Bradshaw N, Grigorieff N, Kern D. From primordial clocks to circadian oscillators. Nature. 2023 Apr;616(7955):183-189. doi:10.1038/s41586-023-05836-9. Epub 2023 Mar 22. PMID: 36949197; PMCID: PMC10076222.; http://hdl.handle.net/20.500.14038/52137Test

الإتاحة: https://doi.org/10.1038/s41586-023-05836-9Test
https://doi.org/20.500.14038/52137Test
https://hdl.handle.net/20.500.14038/52137Test

المؤلفون: Maiti, Atanu, Hedger, Adam K, Myint, Wazo, Balachandran, Vanivilasini, Watts, Jonathan K, Schiffer, Celia A, Matsuo, Hiroshi

المساهمون: Biochemistry and Molecular Biotechnology, Institute for Drug Resistance, Morningside Graduate School of Biomedical Sciences, RNA Therapeutics Institute, Schiffer Lab

المصدر: Nature communications ; 13 ; 1 ; 7117 ; England

مصطلحات موضوعية: X-ray crystallography, Enzyme mechanisms

العلاقة: Nature Communications; https://doi.org/10.1038/s41467-022-34752-1Test; Maiti A, Hedger AK, Myint W, Balachandran V, Watts JK, Schiffer CA, Matsuo H. Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state. Nat Commun. 2022 Nov 19;13(1):7117. doi:10.1038/s41467-022-34752-1. PMID: 36402773; PMCID: PMC9675756.; http://hdl.handle.net/20.500.14038/51572Test

الإتاحة: https://doi.org/10.1038/s41467-022-34752-1Test
https://doi.org/20.500.14038/51572Test
https://hdl.handle.net/20.500.14038/51572Test

المؤلفون: Redhead, MA, Owen, CD, Brewitz, L, Collette, AH, Lukacik, P, Strain-Damerell, C, Robinson, SW, Collins, PM, Schäfer, P, Swindells, M, Radoux, CJ, Hopkins, IN, Fearon, D, Douangamath, A, von Delft, F, Malla, TR, Vangeel, L, Vercruysse, T, Thibaut, J, Leyssen, P, Nguyen, T-T, Hull, M, Tumber, A, Hallett, DJ, Schofield, CJ, Stuart, DI, Hopkins, AL, Walsh, MA

مصطلحات موضوعية: SARS-CoV-2, X-ray crystallography, Enzyme mechanisms, High-throughput screening

العلاقة: https://ora.ox.ac.uk/objects/uuid:bd0f4213-3e07-4471-9796-40203a186faaTest; https://doi.org/10.1038/s41598-021-92416-4Test

الإتاحة: https://doi.org/10.1038/s41598-021-92416-4Test
https://ora.ox.ac.uk/objects/uuid:bd0f4213-3e07-4471-9796-40203a186faaTest

المؤلفون: Griffin A. Welfer, Veniamin A. Borin, Luis M. Cortez, Patricia L. Opresko, Pratul K. Agarwal, Bret D. Freudenthal

المصدر: Genes; Volume 14; Issue 2; Pages: 281

مصطلحات موضوعية: telomeres, telomerase, telomere biology disorders, cancer, enzyme mechanisms

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/genes14020281Test

الإتاحة: https://doi.org/10.3390/genes14020281Test