المؤلفون: Hae Won Kim, Duck Hee Kim, Youngji Kim

المصدر: BMC Women's Health, Vol 18, Iss 1, Pp 1-10 (2018)

مصطلحات موضوعية: Awareness, Cervical cancer, Interview, Qualitative research, Gynecology and obstetrics, RG1-991, Public aspects of medicine, RA1-1270

الوصف: Abstract Backgrounds As HPV is a sexually transmitted virus, men are crucial in the prevention of cervical cancer, but research about men’s awareness on cervical cancer is limited. Therefore, in this study, we investigated men’s awareness toward women’s cervical cancer, to thoroughly understand the viewpoints of men, and to emphasize the centrality of the role of men in the prevention of cervical cancer. Methods A qualitative descriptive design was chosen to explore men’s awareness of women’s cervical cancer. Twelve men aged 20–58 were interviewed. Snowball sampling was conducted to recruit participants. Results Most participants stated that they were not interested in women’s health, and that they did not have much knowledge about cause and prevention of cervical cancer. They acknowledged that cervical cancer was different from other cancers, based on cause and prognosis of disease. The recognition of cervical cancer in participants varied widely depending on their relationship with women. Respondents’ recognition of cervical cancer was classified into four types based on a Situational Awareness (SA) model including individual factors (knowledge about cervical cancer, interest in women’s health) and system/task factors (relationship with women, men’s responsibility). Conclusion This study is one of the few studies describing men’s awareness on cervical cancer. Korean men’s awareness level was low, and their concern and knowledge were not good. Some participants thought that cervical cancer can be treated, can be prevented, and is recognized as a disease of a female with men intervening. Our participants perceived that the role of men is necessary for the prevention of cervical cancer. Therefore, a strategy is needed to develop the awareness and knowledge of men on cervical cancer prevention. When planning cervical cancer education for men, phase and type-specific approaches are required, depending on perception level.

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s12905-018-0650-9Test; https://doaj.org/toc/1472-6874Test

الوصول الحر: https://doaj.org/article/9ba4fbb09ca14e268e31aae72fdec1bfTest

المؤلفون: Hae Won Kim, Duck Hee Kim, Yeon Hee Kim, Eun Ju Lee, Saem Yi Kang, Da Bit Lee, Youngji Kim

المصدر: PLoS ONE, Vol 14, Iss 5, p e0217201 (2019)

مصطلحات موضوعية: Medicine, Science

الوصف: To determine the degree to which nurses are aware of cervical cancer and to describe nurses' experiences of caring for patients with cervical cancer. To promote quality of nursing care of cervical cancer, we need to explore their perceptions and nursing experience in doing cervical-cancer care. This study was a qualitative descriptive design. Interviews were conducted with 14 registered nurses. The interviews were audiotaped, transcribed and analyzed. Content analysis was performed. Fourteen nurses who had been working at wards and cancer education centers were recruited in this study. Nine key themes emerged from three categories such as nurses' awareness of cervical cancer, awareness of cervical cancer patient and caring experience. Nurses expressed fear of cervical cancer and helplessness in the face of a life-threatening prognosis. Nurses stated that they might have prejudice about cervical cancer, since it is caused by a sexually transmitted disease. They also recalled that patients with cervical cancer were more sensitive and demanding. Our findings provide a comprehensive and in-depth perspective in understanding the experience of caring for cervical cancer patients. Clinical nurses showed complex emotional reactions to cervical cancer, and expressed prejudice against the sex life of cervical-cancer patients. More education is required to ensure that clinical nurses can provide a nurse-led intervention with patients by managing nurses' fear, prejudice, and the care burden.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/cac983756b474099807a21dc38b8464eTest

المؤلفون: Hae Won Kim, Duck Hee Kim, Hyang Yuol Lee, Young Jin Lee, Hye Young Ahn

المصدر: International Journal of Environmental Research and Public Health; Volume 17; Issue 7; Pages: 2460

مصطلحات موضوعية: pregnancy, preconception care, social perception, focus groups

جغرافية الموضوع: agris

الوصف: The fastest aging society with the lowest fertility rate can be buffered by support for healthy pregnancies using sociocultural approaches. We aimed to address adult perceptions of a healthy pregnancy and explored their needs and concerns about childbirth across the lifespan. We conducted a qualitative study using content analysis to investigate general perceptions of a healthy pregnancy after focus-group interviews with adult men and women. We interviewed 60 participants in nine group sessions of 5 to 8 people per group. Three major themes emerged that affect healthy pregnancies: Taking responsibility for a prepared pregnancy, factors that interfere with a healthy pregnancy, and improving strategies for a healthy pregnancy. For the first theme, the two main concerns were financial and parenthood preparation. Factors interfering with a healthy pregnancy had direct and indirect causes, considering personal, social, and cultural changes. Strategies for a healthy pregnancy included family and workplace support, systematic education, and governmental support for financial preparation and health screening. Participants averred that various kinds of support (financial, healthcare, and career) are needed for a healthy pregnancy and childbirth. This public awareness could promote better decisions toward healthy pregnancy with more sociocultural approaches in the various settings of home, school, and the workplace.

وصف الملف: application/pdf

العلاقة: https://dx.doi.org/10.3390/ijerph17072460Test

الإتاحة: https://doi.org/10.3390/ijerph17072460Test

المؤلفون: Hyun-Ah Kang, Sung Rae Kim, Jin-Ae Kim, Duck-Hee Kim

مصطلحات موضوعية: Genetics, biology, Genetic linkage, Brassica rapa, Nonsense-mediated decay, Brassica, Chromosome, Single-nucleotide polymorphism, Vernalization, Quantitative trait locus, biology.organism_classification

الوصف: Many Brassica species require vernalization (long-term winter-like cooling) for transition to the reproductive stage. In the past several decades, scientific efforts have been made to discern the molecular mechanisms underlying vernalization in many species. Thus, to identify the key regulators required for vernalization in Brassica rapa L., we constructed a linkage map composed of 7,833 single nucleotide polymorphism (SNP) markers using the late-flowering Chinese cabbage (B. rapa L. ssp. pekinensis) inbred line ‘Chiifu’ and the early-flowering yellow sarson (B. rapa L. ssp. trilocularis (Roxb.)) line ‘LP08’ and identified a single major QTL on the upper-arm of the chromosome A02. In addition, we compared the transcriptomes of the lines ‘Chiifu’ and ‘LP08’ at five vernalization time points, including both non-vernalized and post-vernalization conditions. We observed that BrFLC2 was significantly downregulated in the early flowering ‘LP08’ and had two deletion sites around the BrFLC2 genomic region compared with the BrFLC2 genomic region in ‘Chiifu.’ In the present study, we also demonstrate that early flowering in ‘LP08’ line is attributed to the low expression of BrFLC2, which is caused by nonsense-mediated mRNA decay (NMD). Therefore, this study provides a better understanding of the molecular mechanisms underlying floral transition in B. rapa.One sentence summaryNMD-mediated degradation of BrFLC2 mRNA transcripts is the main cause of rapid flowering of oilseed-type B. rapa ‘LP08’ plants.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8d91888bd6aba13fee823d6135797dccTest
https://doi.org/10.1101/2021.05.05.442798Test

المؤلفون: Sun Whoa Choi, Duck Hee Kim

المصدر: Journal of Korean Gerontological Nursing. 19:125-134

مصطلحات موضوعية: medicine.medical_specialty, Job stress, 030504 nursing, business.industry, 06 humanities and the arts, Burnout, 0603 philosophy, ethics and religion, 03 medical and health sciences, Long-term care, Nursing, Family medicine, Health care, medicine, 060301 applied ethics, 0305 other medical science, Resilience (network), business, Gerontology, Accreditation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f26335173ee142fb206fad6901f3a098Test
https://doi.org/10.17079/jkgn.2017.19.2.125Test

المؤلفون: Yeon Hee Kim, Duck Hee Kim, Hae Won Kim, Da Bit Lee, Youngji Kim, Eun Ju Lee, Saem Yi Kang

المصدر: PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0217201 (2019)

مصطلحات موضوعية: Sexually transmitted disease, Health Knowledge, Attitudes, Practice, Health Care Providers, Emotions, Cancer Treatment, Uterine Cervical Neoplasms, Nurses, Social Sciences, Nursing Staff, Hospital, Cervical Cancer, Nursing care, 0302 clinical medicine, Sociology, Medicine and Health Sciences, Psychology, 030212 general & internal medicine, Medical Personnel, Prejudice (legal term), Qualitative Research, Cervical cancer, Multidisciplinary, Social Discrimination, Fear, Professions, Oncology, 030220 oncology & carcinogenesis, Sex life, Medicine, Female, Clinical Competence, Research Article, Adult, medicine.medical_specialty, Patients, Science, 03 medical and health sciences, Young Adult, Nursing Science, Intervention (counseling), medicine, Humans, business.industry, Cancer, Cancers and Neoplasms, Biology and Life Sciences, medicine.disease, Health Care, Family medicine, People and Places, Population Groupings, business, Nurse-Patient Relations, Gynecological Tumors, Qualitative research

الوصف: To determine the degree to which nurses are aware of cervical cancer and to describe nurses' experiences of caring for patients with cervical cancer. To promote quality of nursing care of cervical cancer, we need to explore their perceptions and nursing experience in doing cervical-cancer care. This study was a qualitative descriptive design. Interviews were conducted with 14 registered nurses. The interviews were audiotaped, transcribed and analyzed. Content analysis was performed. Fourteen nurses who had been working at wards and cancer education centers were recruited in this study. Nine key themes emerged from three categories such as nurses’ awareness of cervical cancer, awareness of cervical cancer patient and caring experience. Nurses expressed fear of cervical cancer and helplessness in the face of a life-threatening prognosis. Nurses stated that they might have prejudice about cervical cancer, since it is caused by a sexually transmitted disease. They also recalled that patients with cervical cancer were more sensitive and demanding. Our findings provide a comprehensive and in-depth perspective in understanding the experience of caring for cervical cancer patients. Clinical nurses showed complex emotional reactions to cervical cancer, and expressed prejudice against the sex life of cervical-cancer patients. More education is required to ensure that clinical nurses can provide a nurse-led intervention with patients by managing nurses’ fear, prejudice, and the care burden.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1444d70b2c85e743539ac8022984014dTest
https://pubmed.ncbi.nlm.nih.gov/31112578Test

المؤلفون: Youngji Kim, Duck Hee Kim, Hae Won Kim

المصدر: BMC Women's Health, Vol 18, Iss 1, Pp 1-10 (2018)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Health Knowledge, Attitudes, Practice, Sexual Behavior, Awareness level, Reproductive medicine, Uterine Cervical Neoplasms, Disease, lcsh:Gynecology and obstetrics, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Republic of Korea, medicine, Humans, Interview, 030212 general & internal medicine, lcsh:RG1-991, Qualitative Research, Cervical cancer, business.industry, lcsh:Public aspects of medicine, Qualitative descriptive, Obstetrics and Gynecology, lcsh:RA1-1270, Men, General Medicine, Awareness, Middle Aged, medicine.disease, Snowball sampling, Reproductive Medicine, 030220 oncology & carcinogenesis, Family medicine, Cervical cancer prevention, Women's Health, Female, business, Qualitative research

الوصف: Backgrounds As HPV is a sexually transmitted virus, men are crucial in the prevention of cervical cancer, but research about men’s awareness on cervical cancer is limited. Therefore, in this study, we investigated men’s awareness toward women’s cervical cancer, to thoroughly understand the viewpoints of men, and to emphasize the centrality of the role of men in the prevention of cervical cancer. Methods A qualitative descriptive design was chosen to explore men’s awareness of women’s cervical cancer. Twelve men aged 20–58 were interviewed. Snowball sampling was conducted to recruit participants. Results Most participants stated that they were not interested in women’s health, and that they did not have much knowledge about cause and prevention of cervical cancer. They acknowledged that cervical cancer was different from other cancers, based on cause and prognosis of disease. The recognition of cervical cancer in participants varied widely depending on their relationship with women. Respondents’ recognition of cervical cancer was classified into four types based on a Situational Awareness (SA) model including individual factors (knowledge about cervical cancer, interest in women’s health) and system/task factors (relationship with women, men’s responsibility). Conclusion This study is one of the few studies describing men’s awareness on cervical cancer. Korean men’s awareness level was low, and their concern and knowledge were not good. Some participants thought that cervical cancer can be treated, can be prevented, and is recognized as a disease of a female with men intervening. Our participants perceived that the role of men is necessary for the prevention of cervical cancer. Therefore, a strategy is needed to develop the awareness and knowledge of men on cervical cancer prevention. When planning cervical cancer education for men, phase and type-specific approaches are required, depending on perception level.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e25eeaa71b1c434e0f5a16c58cf5004Test
https://pubmed.ncbi.nlm.nih.gov/30249228Test

المؤلفون: Heui-Chul Gwak, Soo-Hwan Jung, Hye-Jung Choo, Jun-Woo Jeong, Duck-Hee Kim, Young-Jun Kim, Sang-Myung Roh

المصدر: Journal of Korean Foot and Ankle Society. 23:35

مصطلحات موضوعية: medicine.anatomical_structure, medicine.diagnostic_test, business.industry, Medicine, Magnetic resonance imaging, Lipoma arborescens, Anatomy, Ankle, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::360e84b86dbc6a6addefc4193f2630d0Test
https://doi.org/10.14193/jkfas.2019.23.1.35Test

المؤلفون: Duck-Hee Kim, Eun-Mi Kim, Jun-Seong Park, Juhan Kim, Byung-Gee Kim, Joo-Hyun Seo

المصدر: Applied Microbiology and Biotechnology. 97:8031-8039

مصطلحات موضوعية: chemistry.chemical_classification, Glycosylation, Sapogenins, Chromatography, Ginsenosides, Molecular Structure, Sphingobacterium multivorum, Plant Extracts, Chemistry, Electrospray ionization, General Medicine, Applied Microbiology and Biotechnology, High-performance liquid chromatography, Ginseng, chemistry.chemical_compound, Enzyme, Biochemistry, Biotransformation, Tandem Mass Spectrometry, Ginsenoside, Sphingobacterium, Specific activity, Chromatography, High Pressure Liquid, Biotechnology

الوصف: Using enrichment culture, Sphingobacterium multivorum GIN723 (KCCM80060) was isolated as having activity for deglycosylation of compound K and ginsenoside F1 to produce ginsenoside aglycons such as S-protopanaxadiol (PPD(S)) and S-protopanaxatriol (PPT(S)). Through BLAST search, purified enzyme from S. multivorum GIN723 was revealed to be the outer membrane protein. The purified enzyme from S. multivorum GIN723 has unique specificity for the glucose moiety. However, it has activity with PPD and PPT group ginsenosides such as ginsenosides Rb1, Rb2, Rb3, Rc, F2, CK, Rh2, Re, and F1. From these results, it was predicted that the enzyme has activity on several ginsenosides. Therefore, the biotransformation pathway from Rb1, which is a major, highly glycosylated compound of ginseng, was analyzed using high-performance liquid chromatography and electrospray ionization mass spectrometry/mass spectrometry. The dominant biotransformation pathway from Rb1 to PPD(S) was determined to be Rb1 → Gp-XVII → Gp-LXXV → CK → PPD(S). S. multivorum GIN723 can be used as a whole cell biocatalyst because its activity as whole cells is nine times higher than its activity as cell extracts. The specific activity of whole cells is 2.89 nmol/mg/min in the production of PPD(S). On the other hand, the specific activity of cell extracts is 0.32 nmol/mg/min. The productivity of this enzyme in whole cell form is 500 mg/1 l of cultured cell. Its optimum reaction condition is 10 mM of calcium ions added to a phosphate buffer with a pH of 8.5.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309bfd8dc848aac7cab566d3eaa84cc4Test
https://doi.org/10.1007/s00253-013-4982-yTest

المؤلفون: Chang Ahn Seol, Yong Pil Chong, Duck Hee Kim, Misuk Ji, Mi Na Kim, Heungsup Sung

المصدر: Annals of Laboratory Medicine

مصطلحات موضوعية: medicine.drug_class, hsp65, Clinical Biochemistry, Antibiotics, Microscopic Polyangiitis, Case Report, Nocardia, Microbiology, Asian People, Bacterial Proteins, Adrenal Cortex Hormones, RNA, Ribosomal, 16S, Ampicillin, Republic of Korea, medicine, Corticosteroids, Humans, Skin, Scalp, integumentary system, biology, Nocardia brasiliensis, Biochemistry (medical), Nocardiosis, Sequence Analysis, DNA, General Medicine, Sulbactam, Middle Aged, Amoxicillin, bacterial infections and mycoses, biology.organism_classification, medicine.disease, Clinical Microbiology, Mycetoma, Female, Microscopic polyangiitis, Nocardia pseudobrasiliensis, 16S ribosomal RNA, medicine.drug

الوصف: Nocardia pseudobrasiliensis is predominantly associated with invasive infections in immunocompromised patients. We report a case of disseminated mycetoma caused by N. pseudobrasiliensis in a 57-yr-old woman with microscopic polyangiitis, who was treated for 3 months with corticosteroids. The same organism was isolated from mycetoma cultures on the patient's scalp, right arm, and right leg. The phenotypic characteristics of the isolate were consistent with both Nocardia brasiliensis and N. pseudobrasiliensis, i.e., catalase and urease positivity, hydrolysis of esculin, gelatin, casein, hypoxanthine, and tyrosine, but no hydrolysis of xanthine. The isolate was identified as N. pseudobrasiliensis based on 16S rRNA and hsp65 gene sequencing. The patient was treated for 5 days with intravenous ampicillin/sulbactam, at which time both the mycetomas and fever had subsided and discharged on amoxicillin/clavulanate. This case highlights a very rare presentation of mainly cutaneous mycetoma caused by N. pseudobrasiliensis. This is the first reported case of N. pseudobrasiliensis infection in Korea.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b73e2cfe5f0b71cc9b310de8575eb6Test
https://doi.org/10.3343/alm.2013.33.3.203Test