المؤلفون: Aoyagi, Ryuichi, Maehara, Takashi, Koga, Risako, Munemura, Ryusuke, Tomonaga, Tadashi, Murakami, Yuka, Doi, Atsushi, Yamamoto, Hidetaka, Kiyoshima, Tamotsu, Kawano, Shintaro, Nakamura, Seiji

المساهمون: Takeda Science Foundation, Japan Society for the Promotion of Science

المصدر: Journal of Allergy and Clinical Immunology ; volume 153, issue 2, page 513-520.e10 ; ISSN 0091-6749

مصطلحات موضوعية: Immunology, Immunology and Allergy

الإتاحة: https://doi.org/10.1016/j.jaci.2023.08.019
https://api.elsevier.com/content/article/PII:S0091674923010722?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0091674923010722?httpAccept=text/plainTest

المؤلفون: Sonohata,Motoki, Doi,Atsushi, Uchihashi,Kazuyoshi, Hashimoto,Akira, Kii,Sakumo, Inoue,Takao, Mawatari,Masaaki

مصطلحات موضوعية: Journal of Pain Research

الوصف: Motoki Sonohata,1,2,* Atsushi Doi,3,* Kazuyoshi Uchihashi,4 Akira Hashimoto,2 Sakumo Kii,1 Takao Inoue,5 Masaaki Mawatari1 1Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, Saga, Japan; 2Department of Orthopaedic Surgery, Saga Central Hospital, Saga, Japan; 3Department of Rehabilitation, Kumamoto Health Science University, Kumamoto, Japan; 4Department of Surgical Pathology, National Hospital Organization Saga Hospital, Saga, Japan; 5Organization of Research Initiatives, Yamaguchi University, Yamaguchi, Japan*These authors contributed equally to this workCorrespondence: Atsushi Doi, Department of Rehabilitation, Kumamoto Health Science University, 324, Izumi, Kumamoto-kitaku, Kumamoto, 861-5598, Japan, Tel +81-96-275-2111, Email atsushidoi01@gmail.comPurpose: This study used a sciatic nerve injury rat model to investigate the short-term effects of a polyglycolic acid (PGA)-collagen tube for nerve injury in continuity.Materials and Methods: Sixteen female Wistar rats (6– 8 weeks) were used, and the left sciatic nerve was crushed with a Sugita aneurysm clip. Sciatic nerve model rats were randomly categorized into two groups (n = 8; control group, n = 8; nerve wrapping group). Then, we measured four sensory thresholds, magnetically stimulated the lumbar region to induce motor-evoked potentials (MEPs), and evaluated the sciatic nerve histopathologically.Results: In the sensory thresholds, there were significant differences for the main effect in 250 and 2000 Hz stimulation (p = 0.048 and 0.006, respectively). Further, a significant difference was observed with 2000 Hz stimulation at 1 week (p = 0.003). In the heat stimulation, there were significant differences for the main effect in both weeks and groups (p = 0.0002 and 0.0185, respectively). The post-hoc test showed a significant difference between groups only in 2W (p = 0.0283). Three weeks after the surgery, both 2nd and 3rd MEPs waves-related latencies in the nerve wrapping group were significantly shorter than those in the control ...

وصف الملف: text/html

العلاقة: https://www.dovepress.com/short-term-collagen-nerve-wrapping-facilitates-motor-and-sensory-recov-peer-reviewed-fulltext-article-JPRTest

الإتاحة: https://doi.org/10.2147/JPR.S401126
https://www.dovepress.com/short-term-collagen-nerve-wrapping-facilitates-motor-and-sensory-recov-peer-reviewed-fulltext-article-JPRTest

المؤلفون: Kawano, Noriaki, Kyohei, Yamada, Miyoshi, Hiroaki, Yoshida, Noriaki, Ohshima, Kouichi, Arakawa, Fumiko, Nakashima, Kazutaka, Kameda, Takuro, Kogure, Yasunori, Ito, Yuta, Yoshida, Shuro, Kuriyama, Takuro, Nakaike, Takashi, Tochigi, Taro, Takigawa, Ken, Yamashita, Kiyoshi, Toyofuku, Atsushi, Manabe, Tatsuya, Doi, Atsushi, Terasaka, Soushi, Marutsuka, Kouske, Ochiai, Hidenobu, Kikuchi, Ikuo, Mori, Yasuo, Kataoka, Keisuke, Yoshizumi, Tomoharu, Yamauchi, Junji, Yamano, Yoshihisa, Shimoda, Kazuya

المصدر: Renal Replacement Therapy ; volume 9, issue 1 ; ISSN 2059-1381

مصطلحات موضوعية: Transplantation, Urology, Nephrology

الوصف: Backgrounds Therefore, reports on the risk of HTLV-1-related diseases in organ transplantation have increased in recent years, and the management of HTLV in renal transplantation remains a challenge. Patients and methods We retrospectively analyzed four HTLV-1-positive recipients or donors among 89 renal transplantation cases from 2006 to 2021. Results Among the four HTLV-1-positive recipients, two patients developed adult T cell leukemia/lymphoma (ATL) derived from recipients at approximately 3 years (1016 days and 1195 days) after renal transplantation. Case 1 developed lymphoma-type ATL (an extranodal primary cutaneous variant), including skin and pulmonary lesions. The patient achieved CR with FK tapering and CHOP therapy following cord blood stem cell transplantation. However, the patient died 101 days after ATL development because of a severe fungal infection. Case 2 developed acute-type ATL with an unusual phenotype of CD4+8+30+. The patient was treated with FK tapering and palliative therapy because of poor PS. Notably, in case 1, histopathological findings showed high numbers of PD-1-positive TIL cells in ATL, suggesting exhausted T cells and a correlation with the early onset of ATL. Furthermore, in Case 2, histopathological findings revealed CD 30 expression in ATL cells, suggesting the importance of CD 30 in ATL development. Importantly, case 2 showed typical driver mutations, including CCR4 truncation mutations of the C-terminal, TBL1XR1 mutation, and TP53 mutation in the splice site. Notably, our present study and our previous study on renal transplantation strongly indicated that two out of two and one out of 59 “recipient” positive cases developed ATL, respectively. Furthermore, our previous nationwide study 4 out of 10 “donor” positive cases developed HAM. These findings showed that ATL may be derived from HTLV-I+ recipient cells and HAM may be derived from HTLV-1+ donor cells, although the precise mechanism remains unknown. Conclusions Thus, early onset and rapid progression of ATL ...

الإتاحة: https://doi.org/10.1186/s41100-023-00480-5

المؤلفون: Sonohata, Motoki, Doi, Atsushi, Uchihashi, Kazuyoshi, Hashimoto, Akira, Kii, Sakumo, Inoue, Takao, Mawatari, Masaaki

المصدر: Journal of Pain Research ; volume Volume 16, page 1683-1695 ; ISSN 1178-7090

الإتاحة: https://doi.org/10.2147/jpr.s401126
https://www.dovepress.com/getfile.php?fileID=89850Test

المؤلفون: Moriwaki, Kazuki¹ (AUTHOR), Doi, Atsushi¹ (AUTHOR) adoi7abl@gmail.com, Nishigaki, Keisuke¹ (AUTHOR), Tsukamoto, Takuya¹ (AUTHOR), Tanaka, Sawa¹ (AUTHOR), Yamasaki, Reiko¹ (AUTHOR), Fukuda, Keisuke¹ (AUTHOR), Yoshiyama, Tomotaka² (AUTHOR), Kawarabayashi, Takahiko¹ (AUTHOR), Fukuda, Daiju² (AUTHOR)

المصدر: Journal of Cardiovascular Electrophysiology. May2024, p1. 5p. 3 Illustrations.

المؤلفون: Doi, Atsushi, Moriwaki, Kazuki, Nishigaki, Keisuke, Tsukamoto, Takuya, Tanaka, Sawa, Yamasaki, Reiko, Fukuda, Keisuke, Kawarabayashi, Takahiko, Fukuda, Daiju

المصدر: JACC: Clinical Electrophysiology ; volume 10, issue 2, page 439-446 ; ISSN 2405-500X

الإتاحة: https://doi.org/10.1016/j.jacep.2023.10.017
https://api.elsevier.com/content/article/PII:S2405500X23008083?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2405500X23008083?httpAccept=text/plainTest

المؤلفون: Koga, Risako, Maehara, Takashi, Aoyagi, Ryuichi, Munemura, Ryusuke, Murakami, Yuka, Doi, Atsushi, Kono, Michihito, Yamamoto, Hidetaka, Niiro, Hiroaki, Kiyoshima, Tamotsu, Tanabe, Mika, Nakano, Toshiaki, Matsukuma, Yuta, Kawano, Mitsuhiro, Stone, John H., Pillai, Shiv, Nakamura, Seiji, Kawano, Shintaro

المساهمون: NIH, National Institutes of Health, Takeda Science Foundation, Japan Society for the Promotion of Science, Kanae Foundation for the Promotion of Medical Science

المصدر: Journal of Allergy and Clinical Immunology ; volume 153, issue 4, page 1095-1112 ; ISSN 0091-6749

مصطلحات موضوعية: Immunology, Immunology and Allergy

الإتاحة: https://doi.org/10.1016/j.jaci.2023.11.916
https://api.elsevier.com/content/article/PII:S0091674923024120?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0091674923024120?httpAccept=text/plainTest

المؤلفون: Munemura, Ryusuke, Maehara, Takashi, Murakami, Yuka, Koga, Risako, Aoyagi, Ryuichi, Kaneko, Naoki, Doi, Atsushi, Perugino, Cory A., Della-Torre, Emanuel, Saeki, Takako, Sato, Yasuharu, Yamamoto, Hidetaka, Kiyoshima, Tamotsu, Stone, John H., Pillai, Shiv, Nakamura, Seiji

المساهمون: National Institutes of Health, Rheumatology Research Foundation, Takeda Science Foundation, Japan Society for the Promotion of Science, Kanae Foundation for the Promotion of Medical Science

المصدر: Journal of Allergy and Clinical Immunology ; volume 150, issue 2, page 440-455.e17 ; ISSN 0091-6749

مصطلحات موضوعية: Immunology, Immunology and Allergy

الإتاحة: https://doi.org/10.1016/j.jaci.2022.03.034
https://api.elsevier.com/content/article/PII:S0091674922006224?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0091674922006224?httpAccept=text/plainTest

المؤلفون: Fujisawa, Yoko, Doi, Atsushi, Shintani, Natsuko

الوصف: This review employed a scoping review approach to synthesize studies published between 2015 and 2024, focusing on the depth of processing (DoP) of written corrective feedback (WCF) in second language (L2) writing. The objective was to identify trends and issues in the research methods employed in this area. The publications were extracted from Google Scholar using three keywords. After screening with coding criteria, 15 studies were identified from an initial pool of 1,850 published studies. Our review suggests that most of the selected studies were conducted in university settings and compared different types of WCF as independent variables, with DoP and accuracy as dependent variables. To measure DoP, the two primary methods adopted were think-aloud protocols (TA) and written languaging (WL). The levels of DoP varied across the studies, ranging from two to five. Several gaps in the existing DoP studies were identified and discussed, providing recommendations for future research.

الإتاحة: https://doi.org/10.31219/osf.io/w32r8

المؤلفون: Saga, Norihiko, Doi, Atsushi, Oda, Teruo, Kudoh, Suguru N.

المساهمون: JKA Foundation

المصدر: Frontiers in Neurorobotics ; volume 14 ; ISSN 1662-5218

مصطلحات موضوعية: Artificial Intelligence, Biomedical Engineering

الوصف: Non-invasive brain–computer interfaces (BCIs) based on common electroencephalography (EEG) are limited to specific instrumentation sites and frequency bands. These BCI induce certain targeted electroencephalographic features of cognitive tasks, identify them, and determine BCI's performance, and use machine-learning to extract these electroencephalographic features, which makes them enormously time-consuming. In addition, there is a problem in which the neurorehabilitation using BCI cannot receive ambulatory and immediate rehabilitation training. Therefore, we proposed an exploratory BCI that did not limit the targeted electroencephalographic features. This system did not determine the electroencephalographic features in advance, determined the frequency bands and measurement sites appropriate for detecting electroencephalographic features based on their target movements, measured the electroencephalogram, created each rule (template) with only large “High” or small “Low” electroencephalograms for arbitrarily determined thresholds (classification of cognitive tasks in the imaginary state of moving the feet by the size of the area constituted by the power spectrum of the EEG in each frequency band), and successfully detected the movement intention by detecting the electroencephalogram consistent with the rules during motor tasks using a fuzzy inference-based template matching method (FTM). However, the electroencephalographic features acquired by this BCI are not known, and their usefulness for patients with actual cerebral infarction is not known. Therefore, this study clarifies the electroencephalographic features captured by the heuristic BCI, as well as clarifies the effectiveness and challenges of this system by its application to patients with cerebral infarction.

الإتاحة: https://doi.org/10.3389/fnbot.2020.607706