المؤلفون: Vilafranca Cartagena, Mireia

المساهمون: University/Department: Universitat de Lleida. Departament d'Infermeria

مرشدي الرسالة: Tort Nasarre, Glòria, Blanco Blanco, Joan

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Diabetis mellitus tipus 2, Exercici, Estil de vida, Diabetes mellitus tipo 2, Ejercicio, Estilo de vida, Diabetes Mellitus Type 2, Exercise, Lifestyle, Infermeria

الوصف: Introducció: El tractament de la diabetis mellitus tipus 2 (DM2) inclou activitat física (AF), dieta i medicació. L'AF proporciona beneficis importants per a les persones amb diabetis. Tanmateix, la majoria dels persones amb DM2 no assoleixen els nivells recomanats d'AF. Objectius: L’objectiu principal d’aquesta tesi és explorar com es produeix el canvi d'hàbits en la realització i el manteniment de l’AF en adults amb DM2 que tenen pràctiques d’AF exitoses en les persones dels centres d’atenció primària de Manresa (Catalunya). Metodologia: El primer article és un scoping review on es va realitzar una cerca de bases de dades sistemàtiques rellevants amb el model definit per Arksey i O'Malley. En el segon i tercer estudis es va utilitzar una metodologia descriptiva qualitativa on es van realitzar entrevistes semiestructurades i es va realitzar una anàlisi temàtica segons el model de Brawn i Clarke. Per últim, es va realitzar una revisió sistemàtica d'estudis qualitatius utilitzant el mètode de cerca sistemàtica SPIDER utilitzant una síntesi temàtica de dades qualitatives. Resultats: En el primer article es van identificar sis components: personal, motivació, social, mental, clínic i autoeficàcia. En el segon article van identificar dos temes: integrar l’AF com a estil de vida i trobar suport per canviar l’AF. En el tercer article es van identificar 3 temes: ansietat, por i vulnerabilitat; monitorització insuficient de la diabetis per part del sistema sanitari; i autocura proactiva. En el quart article es van identificar 4 temes: factors relacionats amb l'AF, factors relacionats amb el programa, factors relacionats amb el suport, i factors relacionats amb la persona. Conclusions: Factors claus per poder mantenir l’hàbit de la realització de l’AF han estat els beneficis psicològics i fisiològics al realitzar AF, tenir temps per poder realitzar AF, el suport que rebut i rebre una educació sanitària individualitzada per augmentar la motivació autònoma i promoure el compromís. La persona amb DM2 ben adherits prèviament al tractament que van estar en confinament domiciliari durant la primera onada de la Covid-19 van aconseguir establir rutines d'autocura d’AF i d’alimentació tot i l’aïllament.

الوصف (مترجم): Introducción: El tratamiento de la diabetes mellitus tipo 2 (DM2) incluye actividad física (AF), dieta y medicación. La AF proporciona importantes beneficios para las personas con diabetes. Sin embargo, la mayoría de las personas con DM2 no alcanzan los niveles recomendados de AF. Objetivos: El objetivo principal de esta tesis es explorar cómo se produce el cambio de hábito en la realización y el mantenimiento de la AF en adultos con DM2 que tienen prácticas de AF exitosas en las personas de los centros de atención primaria de Manresa (Cataluña). Metodología: El primer artículo es un scoping review en el que se realizó una búsqueda de bases de datos sistemáticas relevantes con el modelo definido por Arksey y O'Malley. En el segundo y tercer estudio, se utilizó una metodología descriptiva cualitativa en la que se realizaron entrevistas semiestructuradas y se realizó un análisis temático según el modelo de Brawn y Clarke. Por último, se realizó una revisión sistemática de estudios cualitativos utilizando el método de búsqueda sistemática SPIDER utilizando una síntesis temática de datos cualitativos. Resultados: En el primer artículo se identificaron seis componentes: personal, motivación, social, mental, clínico y autoeficacia. En el segundo artículo se identificaron dos temas: integrar la AF como estilo de vida y encontrar soporte para cambiar la AF. En el tercer artículo se identificaron 3 temas: ansiedad, miedo y vulnerabilidad; monitorización insuficiente de la diabetes por parte del sistema sanitario; y autocuidado proactivo. En el cuarto artículo se identificaron 4 temas: factores relacionados con la AF, factores relacionados con el programa, factores relacionados con el soporte, y factores relacionados con la persona. Conclusiones: Factores claves para poder mantener el hábito de la realización de la AF han sido los beneficios psicológicos y fisiológicos al realizar AF, tener tiempo para poder realizar AF, el apoyo recibido y recibir una educación sanitaria individualizada para aumentar la motivación autónoma y promover el compromiso. Las personas con DM2 bien adheridos previamente al tratamiento que estuvieron en confinamiento domiciliario durante la primera ola de la Covid-19 consiguieron establecer rutinas de autocuidado de AF y de alimentación a pesar del aislamiento.
Introduction: The treatment of diabetes mellitus type 2 (DM2) includes physical activity (PA), diet and medication. FA provides important benefits for people with diabetes. However, most DM2 patients do not achieve recommended FA levels. Objectives: The main objective of this thesis is to explore how the change in habits occurs in the performance and maintenance of PA in adults with DM2 who have successful PA practices in patients of primary care centers from Manresa (Catalonia). Methodology: The first article is a scoping review where a search was made of relevant systematic databases using the model defined by Arksey and O'Malley. In the second and third studies, a qualitative descriptive methodology was used where semistructured interviews were carried out and a thematic analysis was carried out according to Brawn and Clarke's model. Finally, a systematic review of qualitative studies was conducted using the SPIDER systematic search method using a thematic synthesis of qualitative data. Results: Six components were identified in the first article: personal, motivational, social, mental, clinical and self-efficacy. Two themes were identified in the second article: integrating PA as a lifestyle and finding support to change PA. In the third article, 3 themes were identified: anxiety, fear and vulnerability; insufficient monitoring of diabetes by the healthcare system; and proactive self-care. In the fourth article, 4 themes were identified: FA-related factors, program-related factors, support-related factors, and patient-related factors. Conclusions: Key factors to be able to maintain the habit of doing AF have been the psychological and physiological benefits of doing AF, having time to perform PA, the support received and receiving individualized health education to increase motivation autonomous and promote commitment. DM2 patients previously well-adherent to treatment who were under home confinement during the first wave of Covid-19 managed to establish FA self-care and feeding routines despite isolation. Keywords: Diabetes Mellitus Type 2, exercise, motivation, lifestyle, Sedentary Behaviour, qualitative research, Systematic Review.

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/690049Test

المؤلفون: Vlacho, Bogdan

مرشدي الرسالة: Farré Albaladejo, Magí, Franch Nadal, Josep, Mundet i Tudurí, Xavier

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Utilització fàrmacs, Utilización fármacos, Drug use, Diabetis mellitus tipus 2, Diabetes mellitus tipo 2, Diabetes mellitus type 2, Macro dades, Macro datos, Big data, Ciències de la Salut

الوصف: A la pràctica clínica és molt comú afegir un segon fàrmac antidiabètic al tractament amb la metformina per millorar el control glucèmic i reduir els riscos de malaltia cardiovascular i renal entre els pacients amb diabetis mellitus tipus 2. Els inhibidors del pèptid de dipeptidil-4 (iDPP -4), els inhibidors del cotransportador de glucosa en sodi tipus 2 (iSGLT-2) i sulfonilurees (SU) són les tres classes fàrmacs més combinats amb la metformina. L'objectiu de l'estudi eControl Met+ era comparar les dades d'eficàcia, adherència i seguretat després de l'addició d'iDPP-4, iSGLT-2 o SU a la metformina en condicions de pràctica clínica habitual. Addicionalment es va realitzar una anàlisi per comparar la seguretat cardiovascular i mortalitat entre els usuaris que van iniciar tractament amb iSGLT-2 davant d'un altre tractament antidiabètics. Els subjectes inclosos es van aparellar per característiques de base clínicament rellevant per a cada anàlisi. La font de dades era la base de dades (SIDIAP) que registra totes les patologies, proves diagnòstiques i tractaments de les persones ateses als centres d'atenció primària de l'Institut Català de la Salut. La proporció de pacients que van aconseguir la reducció combinada de HbA1c (≥0,5%) i pes (≥3%) després de l'addició d'iDPP-4, iSGLT-2 o SU va ser: 23,3%, 40,2% i 14,7% respectivament. Els usuaris de iSGLT-2 tenien 1,7 vegades més probabilitats d'aconseguir bona adherència en comparació dels usuaris de iDPP-4 i 2,8 vegades més probabilitats en comparació dels usuaris de SU. No es van observar diferències pels esdeveniments adversos entre els grups de tractament. L'ús de iSGLT-2 es va associar amb un risc d'insuficiència cardíaca menor (HR: 0,59, interval de confiança [IC] del 95%: 0,47;0,74, p<0,001), mortalitat qualsevol causa (HR=0 ,41, IC del 95%: 0,31;0,54, p<0,001), o combinació dels dos esdeveniments (HR=0,55, IC95%: 0,47;0,63, p<0,001). Les persones que van iniciar tractament amb un iSGLT-2 en combinació amb la metformina van aconseguir millors resultats per a l'objectiu de reducció de pes i HbA1c i tenien millor adherència al tractament comparant amb la resta de grups. La iniciació de tractament antidiabètic amb SGLT-2i es va associar amb un risc menor d'esdeveniments greus.

الوصف (مترجم): En la práctica clínica es muy habitual añadir un segundo fármaco antidiabético al tratamiento con la metformina para mejorar el control glucémico y reducir los riesgos de enfermedad cardiovascular y renal entre los pacientes con diabetes mellitus tipo 2. Los inhibidores del péptido de dipeptidil-4 (iDPP-4), los inhibidores del co-transportador de glucosa en sodio tipo 2 (iSGLT-2) y sulfonilureas (SU) son las tres clases fármacos más frecuentemente combinados con la metformina. El objetivo del estudio eControl Met+ fue comparar los datos de eficacia, adherencia y seguridad después de la adición de iDPP-4, iSGLT-2 o SU a la metformina en condiciones de la práctica clínica habitual. Adicionalmente se realizó un análisis para comparar la seguridad cardiovascular y mortalidad entre los usuarios que iniciaron tratamiento con iSGLT-2 frente a otro tratamiento antidiabéticos. Los sujetos incluidos se emparejaron por características de base clínicamente relevante para cada análisis. Como fuente de datos se utilizó la base de datos (SIDIAP) que registra todas las patologías, pruebas diagnósticas y tratamientos de las personas atendidas en los centros de Atención Primaria del Instituto Catalán de la Salud. La proporción de pacientes que consiguieron la reducción combinada de HbA1c (≥0,5%) y peso (≥3%) después de la adición de iDPP-4, iSGLT-2 o SU a la metformina fue: 23,3%, 40,2% y 14,7%, respectivamente. Los usuarios de iSGLT-2 tenían 1,7 veces más probabilidades de conseguir buena adherencia en comparación con los usuarios de iDPP-4 y 2,8 veces más probabilidades en comparación con los usuarios de SU. No se observaron diferencias para los eventos adversos entre los grupos de tratamiento. El uso de iSGLT-2 se asoció con un menor riesgo de insuficiencia cardíaca (HR: 0,59, intervalo de confianza [IC] del 95%: 0,47; 0,74, p<0,001), mortalidad cualquier causa (HR=0,41; IC del 95%: 0,31; 0,54, p<0,001), o combinación de los dos eventos (HR=0,55, IC 95%: 0,47; 0,63, p<0,001). Las personas que iniciaron tratamiento con un iSGLT-2 en combinación con la metformina consiguieron mejor resultados para el objetivo reducción de peso y HbA1c y tenían mejor adherencia al tratamiento comparando con el resto de grupos. La iniciación de tratamiento antidiabético con iSGLT-2 se asoció con un menor riesgo de eventos graves.
In clinical practice, adding a second antidiabetic drug to metformin treatment is very common to improve glycemic control and reduce the risks of cardiovascular and renal disease among patients with type 2 diabetes mellitus. Dipeptidyl-4 peptide inhibitors (DPP -4i), sodium-glucose co-transporter type 2 (SGLT2i) inhibitors, and sulfonylureas (SU) are the three-drug classes most often combined with metformin. The objective of the eControl Met+ study was to compare the efficacy, adherence, and safety data after the addition of DPP-4i, SGLT-2i, or SU to metformin under routine clinical practice conditions. Additionally, an analysis was performed to compare cardiovascular safety and mortality among users who started treatment with iSGLT-2 versus another antidiabetic treatment. Included subjects were matched for clinically relevant baseline characteristics for each analysis. The data source was the database (SIDIAP) that records all pathologies, diagnostic tests and treatments of people treated at the Primary Care centres of the Catalan Institute of Health. The proportion of patients who achieved the combined reduction in HbA1c (≥0.5%) and weight (≥3%) after the addition of DPP-4i, SGLT-2i, or SU was: 23.3%, 40.2% and 14.7%, respectively. SGLT-2i users were 1.7 times more likely to achieve good adherence than DPP-4i users and 2.8 times more likely than SU users. No differences were observed for adverse events between the treatment groups. The use of SGLT2i was associated with a lower risk of heart failure (HR: 0.59, 95% confidence interval [CI]: 0.47;0.74, p<0.001), all-cause mortality (HR=0 .41, 95% CI: 0.31; 0.54, p<0.001), or a combination of the two events (HR=0.55, 95% CI: 0.47;0.63, p<0.001). Persons who initiated treatment with an SGLT-2i in combination with metformin achieved better results for the objective weight reduction and HbA1c and had better adherence to treatment compared to the rest of the groups. Initiation of antidiabetic treatment with SGLT-2i was associated with a lower risk of serious events.
Universitat Autònoma de Barcelona. Programa de Doctorat en Farmacologia

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/687806Test

المؤلفون: Harcke, Katri, Lindunger, Anders, Kollinius, Erik, Gebreslassie, Mihretab, Morawski, Anna Ugarph, Nylen, Charlotta, Peterson, Magnus, 1966, Yucel-Lindberg, Tuelay, Ostenson, Claes-Goran, Skott, Pia, Stattin, Nouha Saleh

المصدر: Scandinavian Journal of Primary Health Care. 42(1):170-177

مصطلحات موضوعية: Diabetes mellitus type 2, oral health, periodontitis, primary health care, prediabetic state, noncommunicable disease

الوصف: Objective: Describe a method in a real-world setting to identify persons with undiagnosed prediabetes and type 2 diabetes through an interprofessional collaboration between Public Dental Services and Primary Health Care in Regions Stockholm.Design: A descriptive observational study.Setting: The study was conducted at seven sites in the region of Stockholm, Sweden. Each collaborating site consisted of a primary health clinic and dental clinic.Subjects: Study participants included adults over 18 years of age who visited the Public Dental Services and did not have a medical history of prediabetes or type 2 diabetes.Main outcome measures: Selective screening is conducted in accordance with a risk assessment protocol at the Public Dental Services. In the investigated method, DentDi (Dental and Diabetes), adults diagnosed with caries and/or periodontitis over a cut-off value are referred to the Primary Health Care clinic for screening of prediabetes and type 2 diabetes.Results: DentDi, introduced at seven sites, between the years 2017 and 2020, all of which continue to use the method today. A total of 863 participants from the Public Dental Services were referred to the Primary Health Care. Of those 396 accepted the invitation to undergo screening at the primary health care centre. Twenty-four individuals did not meet the inclusion criteria, resulting in a total of 372 persons being included in the study. Among the 372 participants, 27% (101) had elevated glucose levels, of which 12 were diagnosed with type 2 diabetes and 89 with prediabetes according to the study classification.Conclusions: DentDi is a feasible method of interprofessional collaboration where each profession contributes with the competence included in everyday clinical practice for early identification of persons with prediabetes and type 2 diabetes with a complete chain of care. The goal is to disseminate this method throughout Stockholm County and even other regions in Sweden.

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-531616Test
https://doi.org/10.1080/02813432.2023.2299114Test
https://uu.diva-portal.org/smash/get/diva2:1871521/FULLTEXT01.pdfTest

المؤلفون: HUANG Shuwei, ZHOU Zhiheng, FENG Tianyuan, LIU Li, DENG Guangpu, LI Yaotian, ZHU Hong

المصدر: Zhongguo quanke yixue, Vol 27, Iss 19, Pp 2364-2374 (2024)

مصطلحات موضوعية: diabetes mellitus, type 2, hyperuricemia, middle aged, aged, insulin resistance, risk assessment, Medicine

الوصف: Background In China, there is a significant prevalence of type 2 diabetes patients (T2DM) , who also have an increased risk of developing secondary hyperuricemia (HUA) . Patients with T2DM who develops HUA are at increased risk of developing further problems, which could have detrimental effects on their health. Consequently, it is crucial to promptly identify individuals who have a high risk of developing secondary HUA and to begin early prevention and therapy. Objective Exploring the predictive value of common insulin resistance (IR) surrogates for the HUA in middle-aged and elderly T2DM patients. And employ a subset of these metrics as predictive metrics for the occurrence and progression of HUA. Methods Using stratified random sampling, 479 individuals with type 2 diabetes mellitus (T2DM) and 1 528 patients with non-hyperuricemia (NHUA) were chosen from seven community health service centers in Shenzhen between January and March 2023. Multivariate Logistic regression analysis was used to evaluate the effects of various insulin resistance (IR) metrics and their quartiles on the incidence of HUA in middle-aged and older type 2 diabetic patients. Triglyceride-high density lipoprotein cholesterol (TG/HDL-C) index, non-high density lipoprotein cholesterol ratio (Non-HDL-C/HDL-C) index, triglyceride glucose (TyG) index, triglyceride glucose body mass (TyG-BMI) index, triglyceride glucose waist circumference (TyG-WC) index, and insulin resistance metabolism (METS-IR) index are some of these metrics. The predictive efficacy of several IR substitution measures for HUA in middle-aged and older T2DM patients was assessed using the ROC curve. The CHARLS database's cohort data from 2011 and 2015 were filtered in order to create a nested case-control that would validate the predictive power of different IR alternative indicators for the likelihood of HUA. Results Multivariate Logistic regression study revealed that the METS-IR index, TG/HDL-C index, Non HDL-C/HDL-C index, TyG index, TyG-BMI index, TyG-WC index, and TG/HDL-C index were independent influencing factors for the occurrence of HUA (P

وصف الملف: electronic resource

العلاقة: https://www.chinagp.net/fileup/1007-9572/PDF/20230472.pdfTest; https://doaj.org/toc/1007-9572Test

الوصول الحر: https://doaj.org/article/7776ff1e09074bd0a6744f8e85bf9ff9Test

المؤلفون: ZHOU Xiao, ZHOU Yunting, KONG Xiaocen, LIU Xiaomei, YUAN Lu, JING Ting, WANG Weiping, LI Huiqin

المصدر: Zhongguo quanke yixue, Vol 27, Iss 21, Pp 2572-2577 (2024)

مصطلحات موضوعية: blood glucose self-monitoring, continuous glucose monitoring, diabetes mellitus, type 2, health education, blood glucose profile, time in range, Medicine

الوصف: Background Continuous glucose monitoring (CGM) is rarely applied to outpatient treatments. The impact of CGM-based diabetes education to change unhealthy living and eating habits on the blood glucose profile is still unclear. Objective Based on the retrospective results of CGM, outpatient education such as diet and exercise was applied to outpatients with type 2 diabetes mellitus (T2DM) who were managed by oral hypoglycemic drugs. This study aims to evaluate the effects on blood glucose profiles. Methods A total of 88 outpatient T2DM patients medicated with oral hypoglycemic drugs in the Department of Endocrinology, Nanjing First Hospital in 2021 were included and managed by CGM, involving 60 male and 28 female patients. The enrolled patients maintained the original hypoglycemic treatment regimen and lifestyle habits on the 1st to 3rd day. On the 4th day, we downloaded and analyzed CGM data and provided outpatient education based on individualized eating habit and exercise. On the 6th day, the CGM sensor and recorder were removed. CGM data on the 2nd day versus 5th day were compared for dynamic blood glucose profiles, including the 24 h mean blood glucose (MBG), mean amplitude of glycemic excursion (MAGE) and time in target glucose range (TIR) . Results Based on the CGM results, MBG in outpatients with T2DM on the 5th day after outpatient education was significantly reduced from (8.34±1.97) mmol/L to (7.85±1.65) mmol/L (P

وصف الملف: electronic resource

العلاقة: https://www.chinagp.net/fileup/1007-9572/PDF/2023-090578.pdfTest; https://doaj.org/toc/1007-9572Test

الوصول الحر: https://doaj.org/article/aaf79282f0ee4041bddb850805f2aaa2Test

المؤلفون: Yeonji Kang, Minji Kang, Hyunjung Lim

المصدر: BMC Public Health, Vol 24, Iss 1, Pp 1-12 (2024)

مصطلحات موضوعية: Meals, Intermittent fasting, Hyperglycemia, Prediabetic state, Diabetes Mellitus, type 2, Circadian clocks, Public aspects of medicine, RA1-1270

الوصف: Abstract Background Glucose metabolism regulation is influenced by age and meal skipping, although research on their interplay with hyperglycemia remains limited. This study aims to explore the intricate relationship between meal-skipping patterns and hyperglycemia risk across distinct age groups in South Korean adults. Methods Utilizing data from the Korea National Health and Nutrition Examination Surveys (KNHANES) conducted from 2013 to 2020, comprising 28,530 individuals aged 19 years and older, this study employed multivariable logistic regression models to examine the associations between meal-skipping patterns and the risk of hyperglycemia. Results Meal-skipping patterns were categorized into three groups: no skipping (NS), skipping breakfast (SB), and skipping dinner (SD). Age groups were defined as “young” (aged 19–44), “middle-aged” (aged 45–64), and “elderly” adults (over 65 years old). Among “young” adults, SB was associated with a 1.33-fold higher risk of hyperglycemia (OR = 1.33, 95% CI = 1.14–1.54) compared to NS. Conversely, in “elderly” adults, SD was linked to a 0.49-fold reduced risk (95% CI = 0.29–0.82) when compared to NS. Additionally, we observed that the Korean Health Eating Index (KHEI) scores, representing the quality of diet on a scale of 0 to 100, were consistently lower in SB compared to NS across all age groups. Intriguingly, specifically among the “elderly” group, this score was higher in SD compared to NS (p

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1471-2458Test

الوصول الحر: https://doaj.org/article/18f6863cc48e49f8940fe220f6025135Test

المؤلفون: Neydi F SOUISA, Budi SANTOSA, Edward Kurnia Setiawan LIMIJADI

المصدر: Modern Medicine, Vol 31, Iss 2, Pp 117-122 (2024)

مصطلحات موضوعية: hba1c, hdl, triglyceride, coronary heart disease, diabetes mellitus type 2, Medicine, Medicine (General), R5-920

الوصف: Background: Coronary Heart Disease (CHD) is a disease caused by the narrowing of the coronary artery wall as a result of the atherosclerosis process. Atherosclerosis plays an important role from the beginning of plaque formation until plaque rupture which causes blood clots. Diabetes mellitus and dyslipidemia are one of the major risk factors for CHD. In patients with type 2 Diabetes Mellitus, there was an altered lipid profile which led to endothelial damage that caused the formation of atherosclerosis. HDL cholesterol labeled as good cholesterol was decreased due to uncontrolled LDL cholesterol labeled as bad cholesterol. LDL cholesterol synthesis process was disrupted then causing plaque formation in the arteries which causes CHD. Aim: The aim of this study was to analysis correlation between HbA1c levels, triglyceride levels, HDL levels and the degree of stenosis in coronary heart disease sufferers with type 2 diabetes mellitus. Method: This study was an observational cross-sectional analytical study with total of 51 patients with CHD who underwent cardiac catheterization at Telogorejo Hospital. Semarang. The correlation test in this study using the Spearman test with p

وصف الملف: electronic resource

العلاقة: https://medicinamoderna.ro/wp-content/uploads/2024/06/Correlation-of-Hba1c-Triglyceride-HDL-with-the-Degree-of-Stenosis-in-Coronary-Heart-Patients-withTest-Type-2-Diabetes-Mellitus.pdf; https://doaj.org/toc/1223-0472Test; https://doaj.org/toc/2360-2473Test

الوصول الحر: https://doaj.org/article/d12a644ee5e448259143b5daae8e750eTest

المؤلفون: Mohammad Ishaq Soltaninia, Zohreh Kahramfar, Leili Tapak, Shiva Borzouei

المصدر: پزشکی بالینی ابن سینا, Vol 31, Iss 1, Pp 47-53 (2024)

مصطلحات موضوعية: diabetes mellitus type 2, hemoglobin a1c, obstructive sleep apnea, sleepiness, Medicine

الوصف: Background and Objective: Lack of sleep and insomnia are associated with an increase in the risk of diabetes. Sleep disorders in diabetic people are significantly higher than in healthy people. Moreover, sleep duration is related to blood sugar control in diabetes. This study was conducted with the purpose of investigating the level of sleepiness and obstructive sleep apnea in type 2 diabetic patients and its relationship with glycemic levels. Materials and Methods: This cross-sectional study was conducted on 200 patients with type 2 diabetes referred to Shahid Beheshti Hospital in Hamadan in­ 2023­. Diabetes control status was evaluated by hemoglobin A1c, and the frequency of sleepiness and obstructive sleep apnea was assessed by the Epworth Sleepiness Scale and STOP-BANG questionnaires. Data analysis was done using SPSS 26 statistical software. Results: The mean age of the participants was 56.16 ± 9.77 years. A significant difference was observed between the frequency of daily sleepiness score with gender (P

وصف الملف: electronic resource

العلاقة: http://sjh.umsha.ac.ir/article-1-2947-en.pdfTest; https://doaj.org/toc/2588-722XTest; https://doaj.org/toc/2588-7238Test

الوصول الحر: https://doaj.org/article/907e77c74ed24253a965debc5e549520Test

المؤلفون: Kai Lin, Mi Yao, Xinxin Ji, Rouyan Li, Lesley Andrew, Jacques Oosthuizen, Moira Sim, Yongsong Chen

المصدر: BMC Primary Care, Vol 25, Iss 1, Pp 1-14 (2024)

مصطلحات موضوعية: Diabetes mellitus type 2, Treatment burden, Patient reported outcome measurement, Instrument, Measurement properties, Primary care settings, Medicine (General), R5-920

الوصف: Abstract Background Measuring treatment burden is important for the effective management of Type 2 Diabetes Mellitus (T2DM) care. The purpose of this systematic review was to identify the most robust approach for measuring treatment burden in people with T2DM based on existing evidence. Methods Articles from seven databases were retrieved. Qualitative, quantitative, and mixed-methods studies examining treatment burden in adults with T2DM and/or reporting relevant experiences were included. A convergent segregated approach with a mixed-methods design of systematic review was employed, creating a measurement framework in a narrative review for consistent critical appraisal. The quality of included studies was assessed using the Joanna Briggs Institute tool. The measurement properties of the instruments were evaluated using the Consensus based Standards for selection of Health Measurement Instruments (COSMIN) checklist. Results A total of 21,584 records were screened, and 26 articles were included, comprising 11 quantitative, 11 qualitative, and 4 mixed-methods studies. A thematic analysis of qualitative data extracted from the included articles summarised a measurement framework encompassing seven core and six associated measurements. The core measurements, including financial, medication, administrative, lifestyle, healthcare, time/travel, and medical information burdens, directly reflect the constructs pertinent to the treatment burden of T2DM. In contrast, the associated measurement themes do not directly reflect the burdens or are less substantiated by current evidence. The results of the COSMIN checklist evaluation demonstrated that the Patient Experience with Treatment and Self-management (PETS), Treatment Burden Questionnaire (TBQ), and Multimorbidity Treatment Burden Questionnaire (MTBQ) have robust instrument development processes. These three instruments, with the highest total counts combining the number of themes covered and "positive" ratings in COSMIN evaluation, were in the top tertile stratification, demonstrating superior applicability for measuring T2DM treatment burden. Conclusions This systematic review provides evidence for the currently superior option of measuring treatment burden in people with T2DM. It also revealed that most current research was conducted in well-resourced institutions, potentially overlooking variability in under-resourced settings.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2731-4553Test

الوصول الحر: https://doaj.org/article/8c922aae5eae4458a420ac01edc9a311Test

المؤلفون: MA Jia, ZHANG Minjue, ZHANG Shaowei, YU Haiyan, CHEN Shen, Gulibaier MAMUTI, HONG Juan, LU Yuan

المصدر: Zhongguo quanke yixue, Vol 27, Iss 16, Pp 1984-1989 (2024)

مصطلحات موضوعية: diabetes mellitus, type 2, aged, cognitive dysfunction, mild cognitive impairment, community health services, root cause analysis, Medicine

الوصف: Background Type 2 diabetes mellitus (T2DM) and mild cognitive impairment (MCI) are common health problems in the elderly in the community. Research on the status and influencing factors of MCI in the elderly with T2DM who participate in community management is needed. Objective To explore the cognitive characteristics and related factors of elderly patients with T2DM complicated with MCI under community management. Methods From July to October 2022, a total of 399 patients with type 2 diabetes over 60 years of age in a community health service center in Shanghai were selected by systematic sampling method. General demographic data and health problems, physical examination and laboratory test results, including fasting blood glucose (FBG), total triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), glycosylated hemoglobin (HbA1c) were collected. They were divided into MCI group (n=157) and non-MCI group (n=242) according to the presence or absence of MCI. Binary Logistic regression analysis was used to explore the influencing factors of MCI in elderly patients with type 2 diabetes under community management. Results The prevalence of MCI was 39.3% (157/399) in community-managed elderly patients with type 2 diabetes. The comparison of cognitive characteristics between MCI group and non-MCI group showed that the MCI group had higher abnormality rates in executive function, orientation, calculation, abstraction, delayed memory, visual perception, naming and attention than the non-MCI group, and the differences were statistically significant (P9% (OR=5.106, 95%CI=2.150-12.130), LDL-C (OR=2.451, 95%CI=1.266-4.743), 7-12 years of education (OR=0.419, 95%CI=0.183-0.960) and >12 years (OR=0.243, 95%CI=0.086-0.692) was the influencing factor for MCI in elderly patients with type 2 diabetes (P9% and high level of LDC. High level of education is a protective factor for MCI in community-managed elderly patients with type 2 diabetes. Early cognitive impairment screening, long-term blood glucose control, and lowering LDL-C levels are helpful to improve the cognitive function of community-managed elderly patients with type 2 diabetes.

وصف الملف: electronic resource

العلاقة: https://www.chinagp.net/fileup/1007-9572/PDF/1712542093452-640379964.pdfTest; https://doaj.org/toc/1007-9572Test

الوصول الحر: https://doaj.org/article/88a0333fe9b845c58804ba41146a3c57Test