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1دورية أكاديمية
المؤلفون: Stefanie C van den Bosch, Demi Van Dalen, Marjan Meinders, Harry van Goor, Stefaan Bergé, Martijn Stommel, Sandra van Dulmen
المصدر: Journal of Medical Internet Research, Vol 26, p e49058 (2024)
مصطلحات موضوعية: Computer applications to medicine. Medical informatics, R858-859.7, Public aspects of medicine, RA1-1270
الوصف: BackgroundDuring the first lockdown of the COVID-19 pandemic, an exponential increase in video consultations replacing in-person outpatient visits was observed in hospitals. Insight into patients’ experiences with this type of consultation is helpful for a broad, sustainable, and patient-centered implementation of video consultation. ObjectiveThis study aims to examine patients’ experiences with video consultation during the COVID-19 pandemic and identify discriminative patient and consultation characteristics to determine when video consultation is most feasible. MethodsA cross-sectional survey study was conducted. Patients aged ≥18 years and scheduled for a video consultation at the outpatient clinic of a Dutch university medical center from August 2020 to December 2020 for all medical specialties were eligible. Patients’ experiences were explored through a study-specific survey using descriptive quantitative statistics. Open-ended questions were qualitatively analyzed and thematically categorized into appreciated aspects and aspects for improvement. Discriminative patient and consultation characteristics were identified using 3 distinctive survey items. Characteristics of patients who scored and those who did not score all 3 items positively were analyzed using binary logistic regression. ResultsA total of 1054 patients were included in the analysis. Most patients (964/1054, 91.46%) were satisfied with their video consultation, with a mean overall grade of 8.6 (SD 1.3) of 10. In the qualitative analyses, 70.02% (738/1054) of the patients cited aspects they appreciated and 44.97% (474/1054) mentioned aspects for improvement during their consultation. Patients with better self-rated health reported a positive evaluation significantly more often (P=.001), which also held true for other medical specialties (vs surgical and nonsurgical specialties; P
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Merlijn Smits, Demi van Dalen, Danny Popping, René Bleeker, Martijn W. J. Stommel, Harry van Goor
المصدر: Frontiers in Digital Health, Vol 5 (2023)
مصطلحات موضوعية: video consultation, evidence-based healthcare design, hybrid care, built environment, human factors, Medicine, Public aspects of medicine, RA1-1270, Electronic computers. Computer science, QA75.5-76.95
الوصف: IntroductionAccelerated by the coronavirus pandemic, the healthcare landscape is rapidly evolving, with a shift towards hybrid care models combining in-person and online care. To support this shift, the Radboudumc, an academic hospital in the Netherlands, decided to redesign an existing space facilitating the conduction of video consultations.MethodThe design process involved participation of end-users to ensure that the physical space met their needs. The look and feel of the area was based on evidence-based design guidelines. Two prototype setups were built and tested, and the feedback informed the final design of the Garden Room.ResultsIdentified end-user needs were divided into 3 major categories entailing consultation room setup, optimal use of technology and practical issues involving room availability. Combined with the look and feel of the hospital, final design requirements were developed. The Garden Room consists of 18 video consultation rooms, 4 shared workspaces, relaxation area with kitchen, and meeting rooms. Specific attention is given to the ergonomics, technology and privacy in the rooms to facilitate optimal video conversations between patients and healthcare providers. In the Garden Room, natural elements and an open design supports working in a healing environment.DiscussionNext challenge will be optimizing the use of the Garden Room, which may be hindered by various barriers like resistance to change, existing work processes, and lack of skills training. To address these barriers and support use of the Garden Room, the hospital should focus on the implementation of education, changes in work processes, and the presence of advocates for telehealth.
وصف الملف: electronic resource
العلاقة: https://www.frontiersin.org/articles/10.3389/fdgth.2023.1198565/fullTest; https://doaj.org/toc/2673-253XTest
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3دورية أكاديمية
المؤلفون: for the Dutch Pancreatic Cancer Group, Stijn van Roessel, Eline C. Soer, Lois A. Daamen, Demi van Dalen, Arantza Fariña Sarasqueta, Martijn W.J. Stommel, I. Quintus Molenaar, H. C. van Santvoort, Vincent C.J. van de Vlasakker, I. H.J.T. de Hingh, Jesse V. Groen, J. Sven D. Mieog, J.L. (Coen) van Dam, C.H.J. (Casper) van Eijck, Geertjan van Tienhoven, Heinz Josef Klümpen, J. W. Wilmink, Olivier R. Busch, Lodewijk A.A. Brosens, B. (Bas) Groot Koerkamp, Joanne Verheij, Marc G. Besselink
المصدر: European Journal of Surgical Oncology vol. 47 no. 10, pp. 2525-2532
الوصف: Introduction: Whereas neoadjuvant chemo(radio)therapy is increasingly used in pancreatic cancer, it is currently not recommended for other periampullary (non-pancreatic) cancers. This has important implications for the relevance of the preoperative diagnosis for pancreatoduodenectomy. This retrospective multicentre cohort study aimed to determine the frequency of clinically relevant misdiagnoses in patients undergoing pancreatoduodenectomy for pancreatic or other periampullary cancer. Methods: Data from all consecutive patients who underwent a pancreatoduodenectomy between 2014 and 2018 were obtained from the prospective Dutch Pancreatic Cancer Audit. The preoperative diagnosis as concluded by the multidisciplinary team (MDT) meeting was compared with the final postoperative diagnosis at pathology to determine the rate of clinically relevant misdiagnosis (defined as missed pancreatic cancer or incorrect diagnosis of pancreatic cancer). Results: In total, 1244 patients underwent pancreatoduodenectomy of whom 203 (16%) had a clinically relevant misdiagnosis preoperatively. Of all patients with a final diagnosis of pancreatic cancer, 13% (87/679) were preoperatively misdiagnosed as distal cholangiocarcinoma (n = 41, 6.0%), ampullary cancer (n = 27, 4.0%) duodenal cancer (n = 16, 2.4%), or other (n = 3, 0.4%). Of all patients with a final diagnosis of periampullary (non-pancreatic) cancer, 21% (116/565) were preoperatively incorrectly diagnosed as pancreatic cancer. Accuracy of preoperative diagnosis was 84% for pancreatic cancer, 71% for distal cholangiocarcinoma, 73% for ampullary cancer and 73% for duodenal cancer. A prediction model for the preoperative likelihood of pancreatic cancer (versus other periampullary cancer) prior to pancreatoduodenectomy demonstrated an AUC of 0.88. Discussion: This retrospective multicentre cohort study showed that 16% of patients have a clinically relevant misdiagnosis that could result in either missing the opportunity of neoadjuvant chemotherapy in patients with pancreatic ...
العلاقة: https://repub.eur.nl/pub/136510Test; urn:hdl:1765/136510
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المؤلفون: Olga Zaborina, Sanjiv Hyoju, Marc G. Besselink, Demi van Dalen, John C. Alverdy, Fons F. van den Berg, Marja A. Boermeester, Hjalmar C. van Santvoort, Willem Joost Wiersinga
المساهمون: AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Surgery, AII - Infectious diseases, Graduate School, Center of Experimental and Molecular Medicine, Infectious diseases
المصدر: Gut
Gut, 70(5):gutjnl-2019-320430, 915-927. BMJ Publishing Groupمصطلحات موضوعية: acute pancreatitis, medicine.drug_class, Antibiotics, Physiology, Butyrate, Gut flora, Systemic inflammation, antibiotics, Cecum, Mice, Immune system, medicine, Animals, Humans, Pancreas, biology, business.industry, Pancreatitis, Acute Necrotizing, Gastroenterology, bacterial infection, Fecal Microbiota Transplantation, biology.organism_classification, medicine.disease, butyrate, Gastrointestinal Microbiome, Mice, Inbred C57BL, Butyrates, Disease Models, Animal, medicine.anatomical_structure, Phenotype, Diet, Western, Disease Progression, Pancreatitis, Acute pancreatitis, medicine.symptom, business, diet
الوصف: ObjectiveThe gut microbiota are the main source of infections in necrotising pancreatitis. We investigated the effect of disruption of the intestinal microbiota by a Western-type diet on mortality and bacterial dissemination in necrotising pancreatitis and its reversal by butyrate supplementation.DesignC57BL/6 mice were fed either standard chow or a Western-type diet for 4 weeks and were then subjected to taurocholate-induced necrotising pancreatitis. Blood and pancreas were collected for bacteriology and immune analysis. The cecum microbiota composition of mice was analysed using 16S rRNA gene amplicon sequencing and cecal content metabolites were analysed by targeted (ie, butyrate) and untargeted metabolomics. Prevention of necrotising pancreatitis in this model was compared between faecal microbiota transplantation (FMT) from healthy mice, antibiotic decontamination against Gram-negative bacteria and oral or systemic butyrate administration. Additionally, the faecal microbiota of patients with pancreatitis and healthy subjects were analysed.ResultsMortality, systemic inflammation and bacterial dissemination were increased in mice fed Western diet and their gut microbiota were characterised by a loss of diversity, a bloom ofEscherichia coliand an altered metabolic profile with butyrate depletion. While antibiotic decontamination decreased mortality, Gram-positive dissemination was increased. Both oral and systemic butyrate supplementation decreased mortality, bacterial dissemination, and reversed the microbiota alterations. Paradoxically, mortality and bacterial dissemination were increased with FMT administration. Finally, patients with acute pancreatitis demonstrated an increase in Proteobacteria and a decrease of butyrate producers compared with healthy subjects.ConclusionButyrate depletion and its repletion appear to play a central role in disease progression towards necrotising pancreatitis.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5397e4e91fc00b9fe339ee78bf584e3Test
https://pubmed.ncbi.nlm.nih.gov/32873697Test -
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المؤلفون: Harm Winters, Kirsten Peperkamp, Demi van Dalen, Dietmar J.O. Ulrich, Hanneke J.P. Tielemans, Arico C. Verhulst
المصدر: Skin Research and Technology, 25, 6, pp. 787-792
Skin Research and Technology
Skin Research and Technology, 25, 787-792مصطلحات موضوعية: Adult, Diagnostic Imaging, Male, Intraclass correlation, Dermatology, behavioral disciplines and activities, 01 natural sciences, Skin thickness, skin elasticity, 010309 optics, Young Adult, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, 0103 physical sciences, DermaLab Combo®, Humans, Elasticity (economics), Aged, Skin, Mathematics, Observer Variation, reliability, skin thickness, ICC, Reproducibility of Results, Original Articles, test‐retest, Equipment Design, Middle Aged, Elasticity, Healthy Volunteers, Women's cancers Radboud Institute for Health Sciences [Radboudumc 17], Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Inter-rater reliability, inter‐rater, Arm, healthy participants, Original Article, Female, Biomedical engineering, Skin elasticity
الوصف: Contains fulltext : 215728.pdf (Publisher’s version ) (Open Access) BACKGROUND: For several purposes, skin parameters like thickness and elasticity can be measured. However, little is known about the accuracy of those measurements. AIM: The aim of this study was to determine the intrarater and test-retest reliability of skin thickness and elasticity measurements performed with the DermaLab Combo(R). METHODS: A total of 49 participants were included in this study. Skin thickness and elasticity were measured at six defined locations on the dominant arm. Measurements were repeated two times by the same observer to determine the test-retest reliability. To determine the inter-rater reliability, a second observer repeated the measurements once. RESULTS: Inter-rater and test-retest reliability for elasticity measurements fluctuates per location and per parameter: Inter-rater intraclass correlation coefficient (ICC) ranged from 0.23 to 0.80, and test-retest ICC ranged from 0.25 to 0.84. Skin thickness was measured reliable by every observer on every location, with a test-retest ICC ranging from 0.71 to 0.83 and an inter-rater ICC ranging from 0.69 to 0.80. CONCLUSION: The DermaLab Combo(R) showed a good inter-rater reliability when measuring skin thickness and elasticity. Not all locations are suitable for reliable inter-rater or test-retest measurements. The device is difficult to use by inexperienced users, as the echo probe is sensitive to small movements.
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108bec707e62328b53a3d6daa45b1fc8Test
https://hdl.handle.net/2066/215728Test