نتائج البحث - "David Lagorce"

31

A leap into the chemical space of protein-protein interaction inhibitors

المؤلفون: Olivier Sperandio, Guillaume Laconde, David Lagorce, Bruno O. Villoutreix, Céline M. Labbé

المساهمون: Molécules Thérapeutiques in silico (MTI), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Sperandio, Olivier

المصدر: Current Pharmaceutical Design
Current Pharmaceutical Design, Bentham Science Publishers, 2012, 18 (30), pp.4648-67
Protein-Protein Interactions in Drug Discovery

مصطلحات موضوعية: Druggability, protein-protein interactions, Bioinformatics, therapeutic targets, 01 natural sciences, Drug likeness, Drug Discovery, MESH: Proteins, Protein Interaction Maps, Enzyme Inhibitors, Chemical space, MESH: Protein Interaction Maps, [INFO.INFO-BI] Computer Science [cs]/Bioinformatics [q-bio.QM], Principal Component Analysis, 0303 health sciences, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Chemistry, Drug discovery, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], MESH: Enzyme Inhibitors, Design drugs, druggability, Protein Binding, enzymes, Computational biology, chemoinformatics, G-Protein Coupled Receptor (GPCR), Article, Protein–protein interaction, Small Molecule Libraries, 03 medical and health sciences, MESH: Computer Simulation, MESH: Drug Discovery, MESH: Small Molecule Libraries, MESH: Protein Binding, Computer Simulation, Set (psychology), 030304 developmental biology, Pharmacology, MESH: Principal Component Analysis, Binding Sites, 010405 organic chemistry, Proteins, compound collection, mutations, 0104 chemical sciences, MESH: Binding Sites, ADME, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f50673bbfe618e15914c8a432263c815Test
https://www.hal.inserm.fr/inserm-00828202/file/Sperandio-CurrPharmDes-Oct2012-for-HAL.pdfTest

32

AMMOS Software: Method and Application

المؤلفون: Bruno O. Villoutreix, Ilza Pajeva, Tania Pencheva, David Lagorce, Maria A. Miteva

المصدر: Methods in Molecular Biology ISBN: 9781617794643

مصطلحات موضوعية: Identification (information), Virtual screening, ComputingMethodologies_PATTERNRECOGNITION, Lead (geology), Software, Drug discovery, Computer science, business.industry, Interface (computing), In silico, Software engineering, business, Automation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::9fcdb7ee01bc00af4e9824b4406643daTest
https://doi.org/10.1007/978-1-61779-465-0_9Test

33

Tyrosine Kinase Syk Non-Enzymatic Inhibitors and Potential Anti-Allergic Drug-Like Compounds Discovered by Virtual and In Vitro Screening

المؤلفون: Pierre Martineau, Guillaume Laconde, Maria A. Miteva, Piona Dariavach, David Lagorce, Bruno O. Villoutreix

المساهمون: Molécules Thérapeutiques in silico (MTI), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de recherche en cancérologie de Montpellier (IRCM - U896 Inserm - UM1), Université Montpellier 1 (UM1)-CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Le Ster, Yves, CRLCC Val d'Aurelle - Paul Lamarque-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Montpellier 1 (UM1)

المصدر: PLoS ONE
PLoS ONE, Public Library of Science, 2011, 6 (6), pp.e21117. ⟨10.1371/journal.pone.0021117⟩
PLoS ONE, Vol 6, Iss 6, p e21117 (2011)

مصطلحات موضوعية: [SDV.IMM] Life Sciences [q-bio]/Immunology, Immunology, Drug Evaluation, Preclinical, Syk, lcsh:Medicine, Biology, Models, Biological, 03 medical and health sciences, 0302 clinical medicine, In vivo, Cell Line, Tumor, Drug Discovery, Anti-Allergic Agents, Animals, Syk Kinase, Mast Cells, Enzyme Inhibitors, lcsh:Science, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Molecular Structure, Drug discovery, Kinase, Allergy and Hypersensitivity, lcsh:R, Intracellular Signaling Peptides and Proteins, Computational Biology, Biological activity, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, Protein-Tyrosine Kinases, Small molecule, In vitro, 3. Good health, Rats, [SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences, Biochemistry, 030220 oncology & carcinogenesis, [SDV.IMM]Life Sciences [q-bio]/Immunology, lcsh:Q, Tyrosine kinase, Research Article, Biotechnology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3125f2fa9b7f92f8f7768022cdb9942fTest
http://europepmc.org/articles/PMC3118801Test

34

Chemical Libraries for Virtual Screening

المؤلفون: David Lagorce, Olivier Sperandio, Maria A. Miteva, Bruno O. Villoutreix

المصدر: In Silico Lead Discovery ISBN: 9781608051427

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a78672f6c1a9d0ced4ad73c9044a4d64Test
https://doi.org/10.2174/978160805142711101010001Test

35

In Silico ADME/Tox Predictions

المؤلفون: Olivier Sperandio, Bruno O. Villoutreix, David Lagorce, Anne-Claude Camproux, Christelle Reynes, Maria A. Miteva

المصدر: ADMET for Medicinal Chemists: A Practical Guide

مصطلحات موضوعية: Computer science, In silico, Combinatorial chemistry, Adme tox

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::336a18b43a3d163b20fea356ca1ce4c4Test
https://doi.org/10.1002/9780470915110.ch2Test

36

دورية أكاديمية

Free Resources to Assist Structure-Based Virtual Ligand Screening Experiments

المؤلفون: Bruno O. Villoutreix, Nicolas Renault, David Lagorce, Matthieu Montes, Maria A. Miteva

المصدر: Current Protein & Peptide Science ; volume 8, issue 4, page 381-411 ; ISSN 1389-2037

الإتاحة: https://doi.org/10.2174/138920307781369391Test
http://eurekaselect.com/article/download/78570Test

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37

DG-AMMOS: A New tool to generate 3D conformation of small molecules using D istance G eometry and A utomated M olecular M echanics O ptimization for in silico S creening

المؤلفون: Tania Pencheva, Bruno O. Villoutreix, David Lagorce, Maria A. Miteva

المساهمون: Molécules Thérapeutiques in silico (MTI), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre of Biomedical Engineering, Bulgarian Academy of Sciences (BAS), We would like to thank the Inserm institute, Paris Descartes University and Paris Diderot University for supports. TP thanks the 'Mairie de Paris' fellowship and the National Science Fund of Bulgaria, BMC, Ed.

المصدر: BMC Chemical Biology
BMC Chemical Biology, BioMed Central, 2009, 9 (1), pp.6. ⟨10.1186/1472-6769-9-6⟩
BMC Chemical Biology, Vol 9, Iss 1, p 6 (2009)

مصطلحات موضوعية: Computer science, In silico, Nanotechnology, Energy minimization, 01 natural sciences, Molecular mechanics, Computational science, lcsh:Biochemistry, 03 medical and health sciences, Drug Discovery, lcsh:QD415-436, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [INFO.INFO-BI] Computer Science [cs]/Bioinformatics [q-bio.QM], 030304 developmental biology, 0303 health sciences, Virtual screening, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Drug discovery, Process (computing), [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Small molecule, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Molecular Medicine, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], Software, Generator (mathematics)