المؤلفون: Hirozumi Sano, Ryoji Kobayashi, Daisuke Suzuki, Masato Yanagi, Daiki Hori, Satoru Matsushima, Kunihiko Kobayashi

المصدر: Pediatrics and Neonatology, Vol 65, Iss 1, Pp 23-30 (2024)

مصطلحات موضوعية: Non-alcoholic fatty liver disease (NAFLD), B-cell precursor acute lymphoblastic leukemia (BCP-ALL), Induction therapy, Prognosis, Pediatrics, RJ1-570

الوصف: Background: A prospective evaluation of non-alcoholic fatty liver disease (NAFLD) during induction therapy for acute lymphoblastic leukemia (ALL) has not been performed. Herein, we prospectively investigated the frequency, risk factors, and outcomes of NAFLD during induction therapy in children and adolescents with B-cell precursor ALL (BCP-ALL). Methods: This study enrolled 74 newly diagnosed BCP-ALL cases aged 1 year and older who were admitted to our department between January 2011 and December 2020. Median age was 6.6 years (1.3–17.5 years). Plain computed tomography (CT) of the upper abdomen was performed before induction therapy, and on days 15 and 29 after initiation of induction therapy. Patients with a liver/spleen CT ratio

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S1875957223001249Test; https://doaj.org/toc/1875-9572Test

الوصول الحر: https://doaj.org/article/1747f9c5e738499f9e9687f357ff7696Test

المؤلفون: Yoshimi Muta, Kazuo Kobayashi, Masao Toyoda, Atsuhito Tone, Daisuke Suzuki, Daisuke Tsuriya, Hideo Machimura, Hidetoshi Shimura, Hiroshi Takeda, Hisashi Yokomizo, Kei Takeshita, Keiichi Chin, Keizo Kanasaki, Kouichi Tamura, Masaaki Miyauchi, Masuo Saburi, Miwa Morita, Miwako Yomota, Moritsugu Kimura, Nobuo Hatori, Shinichi Nakajima, Shun Ito, Shunichiro Tsukamoto, Takashi Murata, Takaya Matsushita, Takayuki Furuki, Takuya Hashimoto, Tomoya Umezono, Yuichi Takashi, Daiji Kawanami

المصدر: Frontiers in Pharmacology, Vol 15 (2024)

مصطلحات موضوعية: sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide 1 receptor agonists, renal outcome, combination therapy, preceding drug, diabetic kidney disease, Therapeutics. Pharmacology, RM1-950

الوصف: Accumulating evidence has demonstrated that both SGLT2 inhibitors (SGLT2i) and GLP-1 receptor agonists (GLP1Ra) have protective effects in patients with diabetic kidney disease. Combination therapy with SGLT2i and GLP1Ra is commonly used in patients with type 2 diabetes (T2D). We previously reported that in combination therapy of SGLT2i and GLP1Ra, the effect on the renal composite outcome did not differ according to the preceding drug. However, it remains unclear how the initiation of combination therapy is associated with the renal function depending on the preceding drug. In this post hoc analysis, we analyzed a total of 643 T2D patients (GLP1Ra-preceding group, n = 331; SGLT2i-preceding group, n = 312) and investigated the differences in annual eGFR decline. Multiple imputation and propensity score matching were performed to compare the annual eGFR decline. The reduction in annual eGFR decline in the SGLT2i-preceding group (pre: −3.5 ± 9.4 mL/min/1.73 m2/year, post: −0.4 ± 6.3 mL/min/1.73 m2/year, p < 0.001), was significantly smaller after the initiation of GLP1Ra, whereas the GLP1Ra-preceding group tended to slow the eGFR decline but not to a statistically significant extent (pre: −2.0 ± 10.9 mL/min/1.73 m2/year, post: −1.8 ± 5.4 mL/min/1.73 m2/year, p = 0.83) after the initiation of SGLT2i. After the addition of GLP1Ra to SGLT2i-treated patients, slower annual eGFR decline was observed. Our data raise the possibility that the renal benefits—especially annual eGFR decline—of combination therapy with SGLT2i and GLP1Ra may be affected by the preceding drug.

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2024.1358573/fullTest; https://doaj.org/toc/1663-9812Test

الوصول الحر: https://doaj.org/article/e387d4d5ba7242e08853f9abf1debf8dTest

المؤلفون: Ryota Hase, Daisuke Suzuki, Cynthia de Luise, Haoqian Chen, Edward Nonnenmacher, Takakazu Higuchi, Kayoko Katayama, Mitsuyo Kinjo, Sadao Jinno, Toshitaka Morishima, Naonobu Sugiyama, Yoshiya Tanaka, Soko Setoguchi

المصدر: BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-10 (2023)

مصطلحات موضوعية: Tuberculosis, Herpes zoster, Nontuberculous mycobacteria infections, Pneumocystis jirovecii pneumonia, Japan, Positive predictive value, Infectious and parasitic diseases, RC109-216

الوصف: Abstract Background To validate Japanese claims-based disease-identifying algorithms for herpes zoster (HZ), Mycobacterium tuberculosis (MTB), nontuberculous mycobacteria infections (NTM), and Pneumocystis jirovecii pneumonia (PJP). Methods VALIDATE-J, a multicenter, cross-sectional, retrospective study, reviewed the administrative claims data and medical records from two Japanese hospitals. Claims-based algorithms were developed by experts to identify HZ, MTB, NTM, and PJP cases among patients treated 2012–2016. Diagnosis was confirmed with three gold standard definitions; positive predictive values (PPVs) were calculated for prevalent (regardless of baseline disease-free period) and incident (preceded by a 12-month disease-free period for the target conditions) cases. Results Of patients identified using claims-based algorithms, a random sample of 377 cases was included: HZ (n = 95 [55 incident cases]); MTB (n = 100 [58]); NTM (n = 82 [50]); and PJP (n = 100 [84]). PPVs ranged from 67.4–70.5% (HZ), 67.0–90.0% (MTB), 18.3–63.4% (NTM), and 20.0–45.0% (PJP) for prevalent cases, and 69.1–70.9% (HZ), 58.6–87.9% (MTB), 10.0–56.0% (NTM), and 22.6–51.2% (PJP) for incident cases, across definitions. Adding treatment to the algorithms increased PPVs for HZ, with a small increase observed for prevalent cases of NTM. Conclusions VALIDATE-J demonstrated moderate to high PPVs for disease-identifying algorithms for HZ and MTB using Japanese claims data.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1471-2334Test

الوصول الحر: https://doaj.org/article/f0f3286b694543e28135ad3471d59841Test

المؤلفون: Yui Sasaki, Daisuke Suzuki, Ryo Tokita, Hiroyuki Takashima, Hirofumi Matsumura, Satoshi Nagoya

المصدر: PLoS ONE, Vol 19, Iss 6 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11146717/?tool=EBITest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/502186e1e0b54ead93818291da61b00eTest

المؤلفون: Ken TAKAHASHI, Daisuke SUZUKI, Sadayuki KIKAWA

المصدر: Quarterly Report of RTRI. 2024, 65(2):77-82

المؤلفون: Tomoko Yamaguchi, Hyo Kyozuka, Yoshihiro Kochi, Fumihiro Ito, Hajime Odajima, Daisuke Suzuki, Yasuhisa Nomura

المصدر: FUKUSHIMA JOURNAL OF MEDICAL SCIENCE. 2024, 70(2):93-98

المؤلفون: Naomi Takahashi, Ryosuke Igari, Chifumi Iseki, Hikaru Kawahara, Daisuke Suzuki, Yuya Suzuki, Hiroyasu Sato, Shingo Koyama, Maki Kobayashi, Yasuyuki Ohta

المصدر: Internal Medicine. 2024, 63(6):857-860

المؤلفون: Chifumi Iseki, Daisuke Suzuki, Hiroyasu Sato, Masafumi Kanoto, Naomi Takahashi, Ryosuke Igari, Shingo Koyama, Toshitada Hiraka, Yasuyuki Ohta, Yuya Suzuki

المصدر: Internal Medicine. 2023, 62(23):3541

المؤلفون: Daisuke SUZUKI, Kazuya KUSAKA, Yoshihisa SAKAIDA, 坂井田 喜久, 日下 一也, 鈴木 大介

المصدر: 材料 / Journal of the Society of Materials Science, Japan. 2023, 72(11):843

المؤلفون: Hirozumi Sano, Ryoji Kobayashi, Satoru Matsushima, Daiki Hori, Masato Yanagi, Daisuke Suzuki, Go Ohba, Hiroshi Yamamoto, Kunihiko Kobayashi

المصدر: Clinical Pediatric Hematology-Oncology, Vol 30, Iss 1, Pp 21-24 (2023)

مصطلحات موضوعية: intralobar nephroblastomatosis (nbm), wilms tumor, chemotherapy, treatment strategy, Pediatrics, RJ1-570, Internal medicine, RC31-1245, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

الوصف: Nephroblastomatosis (NBM) is a precursor of Wilms tumor. We herein report a case in which Wilms tumor was initially suspected and the affected kidney was removed. The tumor was subsequently diagnosed as intralobar NBM and a favorable outcome was achieved with postoperative chemotherapy. A 2-year-old boy who presented with gross hematuria was found to have an enlarged left kidney with hydronephrosis. Needle biopsy of the left kidney suggested Wilms tumor and left nephrectomy was performed. The tumor was histopathologically diagnosed as intralobar NBM. Although NBM is regarded as a precancerous lesion, a definite treatment plan has not yet been established. In the present case, we used a similar chemotherapy regimen to that for Wilms tumor. Eight years after the completion of chemotherapy, Wilms tumor has not developed or recurred. Appropriate management plans need to be developed by accumulating similar cases.

وصف الملف: electronic resource

العلاقة: http://www.cpho.or.kr/journal/view.html?doi=10.15264/cpho.2023.30.1.21Test; https://doaj.org/toc/2233-5250Test

الوصول الحر: https://doaj.org/article/05a5785abd4d4e34a748d863a0aa2622Test