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المؤلفون: Naim Nazef, Cliff C. Cheng, D. Allen Annis, Cheng-Chi Chuang, John D. McCarter, Huw M. Nash, Gerald W. Shipps, Todd Rowe, Robert J.M. Kurzeja
المصدر: Combinatorial Chemistry & High Throughput Screening. 12:760-771
مصطلحات موضوعية: High-throughput screening, Phosphatase, Pyrazole, Mass Spectrometry, Structure-Activity Relationship, chemistry.chemical_compound, Catalytic Domain, Drug Discovery, Combinatorial Chemistry Techniques, Structure–activity relationship, Enzyme Inhibitors, chemistry.chemical_classification, Molecular Structure, biology, Inositol Polyphosphate 5-Phosphatases, Organic Chemistry, Active site, Stereoisomerism, General Medicine, Ligand (biochemistry), Combinatorial chemistry, Phosphoric Monoester Hydrolases, High-Throughput Screening Assays, Computer Science Applications, Enzyme, chemistry, Biochemistry, biology.protein, Pyrazoles
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d151261fb2420ad78b5420bc1e802cd1Test
https://doi.org/10.2174/138620709789104870Test -
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المؤلفون: Donna Carr, Ahmed A. Samatar, Weihong Jin, Yang Nan, Jessie M. English, William T. Windsor, Li Xiao, D. Allen Annis, Tong Wang, Hugh Y. Zhu, Alan B. Cooper, Cheng-Chi Chuang, Paul Kirschmeier, Yongqi Deng, Alan Hruza, Gerald W. Shipps, Priya Dayananth
المصدر: Journal of medicinal chemistry. 57(21)
مصطلحات موضوعية: MAPK/ERK pathway, Pyrrolidines, MAP Kinase Signaling System, Affinity label, Crystallography, X-Ray, environment and public health, Pyrrolidine, Mass Spectrometry, chemistry.chemical_compound, Inhibitory Concentration 50, Structure-Activity Relationship, Drug Discovery, Structure–activity relationship, Anilides, Kinase activity, Phosphorylation, Protein Kinase Inhibitors, Mitogen-Activated Protein Kinase 1, biology, Kinase, Substrate (chemistry), Affinity Labels, enzymes and coenzymes (carbohydrates), Biochemistry, chemistry, biology.protein, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1a311ef544d7d53c3130ec6bb13a5fTest
https://pubmed.ncbi.nlm.nih.gov/25313996Test -
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المؤلفون: Naim Nazef, Huw M. Nash, Margaret Porter Scott, Cheng-Chi Chuang, D. Allen Annis
المصدر: Journal of the American Chemical Society. 126:15495-15503
مصطلحات موضوعية: Stereochemistry, Allosteric regulation, Protein Serine-Threonine Kinases, Ligands, Binding, Competitive, Biochemistry, Chemical synthesis, Mass Spectrometry, Catalysis, Colloid and Surface Chemistry, Affinity chromatography, Proto-Oncogene Proteins, Chemical affinity, Combinatorial Chemistry Techniques, Binding site, Serum Albumin, Chromatography, Receptor, Muscarinic M2, Binding Sites, ZAP-70 Protein-Tyrosine Kinase, Chemistry, Drug discovery, Proteins, Stereoisomerism, General Chemistry, Protein-Tyrosine Kinases, Staurosporine, Ligand (biochemistry), Affinities, Kinetics, Warfarin, Proto-Oncogene Proteins c-akt
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9013eb78b1b8388f9493585457f69fTest
https://doi.org/10.1021/ja048365xTest -
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المؤلفون: D. Allen Annis, Jean Paul A. Orminati, G. R.A. Thaddupathy, Patrick J. Curran, Krishna Kalghatgi, Edward A. Wintner, Gerald W. Shipps, Huw M. Nash, William H. Lee, Kristin E. Rosner, Andrew N. Tyler, Carston R. Wagner, John Athanasopoulos, Lev Vilenchik, Jason S. Felsch
المصدر: International Journal of Mass Spectrometry. 238:77-83
مصطلحات موضوعية: biology, Ligand, Chemistry, Drug discovery, Antagonist, Biological activity, Condensed Matter Physics, Mass spectrometry, medicine.disease_cause, Small molecule, Combinatorial chemistry, Dihydrofolate reductase, biology.protein, medicine, Physical and Theoretical Chemistry, Instrumentation, Escherichia coli, Spectroscopy
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ae966614540c07151bcb313c4614775aTest
https://doi.org/10.1016/j.ijms.2003.11.022Test -
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المؤلفون: Gerald Steven Falchook, Manuel Aivado, Funda Meric-Bernstam, Sanjay Goel, Vincent Guerlavais, Marie Payton, Judy Sing-Zan Wang, David S. Hong, Robert M. Conry, Mansoor N. Saleh, Loren D. Walensky, Manish R. Patel, Ulrich Steidl, Jeffrey R. Infante, Geoffrey I. Shapiro, Ki Y Chung, D. Allen Annis
المصدر: Journal of Clinical Oncology. 35:2505-2505
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Cancer Research, medicine.medical_specialty, Cell cycle checkpoint, MDMX, biology, business.industry, Peptide, Endogeny, Pharmacology, 03 medical and health sciences, 030104 developmental biology, Endocrinology, Oncology, chemistry, Apoptosis, Internal medicine, medicine, biology.protein, Stapled peptide, Mdm2, In patient, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::07d1a6660473756fd356e92a899dd543Test
https://doi.org/10.1200/jco.2017.35.15_suppl.2505Test -
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المؤلفون: John R. Engen, Noriyuki Somerville Kawahata, Thomas E. Wales, D. Allen Annis, Xiangguo Eric Shi, Carl Elkin
مصطلحات موضوعية: Proteases, Stereochemistry, Protein Conformation, Proteolysis, medicine.medical_treatment, Molecular Sequence Data, Peptide, Article, Mass Spectrometry, Analytical Chemistry, chemistry.chemical_compound, Protein structure, Amide, medicine, Pharmacokinetics, Amino Acid Sequence, Peptide sequence, chemistry.chemical_classification, Protease, medicine.diagnostic_test, Deuterium Exchange Measurement, Peptide Fragments, Protein Structure, Tertiary, chemistry, Forecasting, Hydrogen
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1876ffcfa3c141ee218f5c4eede9135bTest
https://europepmc.org/articles/PMC3883098Test/ -
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المؤلفون: Krzysztof Darlak, Hongliang Cai, Eric Feyfant, Tomi K. Sawyer, Packman Kathryn E, Lyubomir T. Vassilev, Christian Tovar, Carl Elkin, Huw M. Nash, James Horstick, D. Allen Annis, Vincent Guerlavais, Anthony M. Manning, Nader Fotouhi, Aditi Mukherjee, Xiangguo E. Shi, Karen A. Olson, Kwong-Him To, Kamala Kesavan, Yong S. Chang, Pamela Berry, Theresa Baker, Zoran Filipovic, Bradford Graves, Farooq Qureshi, Pranoti Gangurde
المصدر: Proceedings of the National Academy of Sciences. 110
مصطلحات موضوعية: Male, Models, Molecular, MDMX, Protein Conformation, Mice, Nude, Antineoplastic Agents, Plasma protein binding, Crystallography, X-Ray, Binding, Competitive, Peptides, Cyclic, Protein Structure, Secondary, Mice, Protein structure, In vivo, Cell Line, Tumor, Neoplasms, medicine, Animals, Humans, Rats, Long-Evans, Multidisciplinary, biology, Cancer, Proto-Oncogene Proteins c-mdm2, HCT116 Cells, medicine.disease, Xenograft Model Antitumor Assays, Rats, PNAS Plus, Mechanism of action, Biochemistry, Area Under Curve, MCF-7 Cells, biology.protein, Cancer research, Mdm2, Female, Target protein, Tumor Suppressor Protein p53, medicine.symptom, Peptides, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bf7583698e4f39a7bb9cea1d284dbfTest
https://doi.org/10.1073/pnas.1303002110Test -
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المؤلفون: D. Allen Annis and, Eric N. Jacobsen
المصدر: Journal of the American Chemical Society. 121:4147-4154
مصطلحات موضوعية: inorganic chemicals, Chemistry, Aryl, Enantioselective synthesis, chemistry.chemical_element, General Chemistry, Biochemistry, Combinatorial chemistry, Catalysis, Kinetic resolution, chemistry.chemical_compound, Colloid and Surface Chemistry, Covalent bond, Reactivity (chemistry), Polystyrene, Cobalt
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b46d19d6a7e3f2c0c8adb3df7f088d61Test
https://doi.org/10.1021/ja984410nTest -
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المؤلفون: Eric N. Jacobsen, D. Allen Annis
المصدر: ChemInform. 30
مصطلحات موضوعية: Hydrolysis, Terminal (electronics), Computational chemistry, Chemistry, Organic chemistry, General Medicine, Polymer supported, Kinetic resolution
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f0e9ee300d9c116759c91bada4373f50Test
https://doi.org/10.1002/chin.199936028Test -
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المؤلفون: Eric N. Jacobsen, D. Allen Annis, Olivier Helluin
المصدر: Angewandte Chemie International Edition. 37:1907-1909
مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, Diastereomer, Enantioselective synthesis, Alcohol, Sequence (biology), General Chemistry, Ring (chemistry), Combinatorial chemistry, Catalysis, Cyclic peptide, chemistry.chemical_compound, Solid-phase synthesis, chemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b4a788450ced05fb8469544ea824b46dTest
https://doi.org/10.1002Test/(sici)1521-3773(19980803)37:13/14<1907::aid-anie1907>3.0.co;2-a