المؤلفون: Campbell, PJ, Getz, G, Korbel, JO, Stuart, JM, Jennings, JL, Stein, LD, Perry, MD, Nahal-Bose, HK, Ouellette, BFF, Li, CH, Rheinbay, E, Nielsen, GP, Sgroi, DC, Wu, CL, Faquin, WC, Deshpande, V, Boutros, PC, Lazar, AJ, Hoadley, KA, Louis, DN, Dursi, LJ, Yung, CK, Bailey, MH, Saksena, G, Raine, KM, Buchhalter, I, Kleinheinz, K, Schlesner, M, Zhang, J, Wang, W, Wheeler, DA, Ding, L, Simpson, JT, O'Connor, BD, Yakneen, S, Ellrott, K, Miyoshi, N, Butler, AP, Royo, R, Shorser, S, Vazquez, M, Rausch, T, Tiao, G, Waszak, SM, Rodriguez-Martin, B, Shringarpure, S, Wu, DY, Demidov, GM, Delaneau, O, Hayashi, S, Imoto, S, Habermann, N, Segre, A, Garrison, E, Cafferkey, A, Alvarez, EG, Heredia-Genestar, JM, Muyas, F, Drechsel, O, Bruzos, AL, Temes, J, Zamora, J, Baez-Ortega, A, Kim, HL, Mashl, RJ, Ye, K, DiBiase, A, Huang, KL, Letunic, I, McLellan, MD, Newhouse, SJ, Shmaya, T, Kumar, S, Wedge, DC, Wright, MH, Yellapantula, VD, Gerstein, M, Khurana, E, Marques-Bonet, T, Navarro, A, Bustamante, CD, Siebert, R, Nakagawa, H, Easton, DF, Ossowski, S, Tubio, JMC, De La Vega, FM, Estivill, X, Yuen, D, Mihaiescu, GL, Omberg, L, Ferretti, V, Sabarinathan, R, Pich, O, Gonzalez-Perez, A, Weiner, AT, Fittall, MW, Demeulemeester, J, Tarabichi, M, Roberts, ND, Van Loo, P, Cortes-Ciriano, I, Urban, L, Park, P, in Zhu, Pitkaenen, E, Li, Y, Saini, N, Klimczak, LJ, Weischenfeldt, J, Sidiropoulos, N, Alexandrov, LB, Rabionet, R, Escaramis, G, Bosio, M, Holik, AZ, Susak, H, Prasad, A, Erkek, S, Calabrese, C, Raeder, B, Harrington, E, Mayes, S, Turner, D, Juul, S, Roberts, SA, Song, L, Koster, R, Mirabello, L, Hua, X, Tanskanen, TJ, Tojo, M, Chen, J, Aaltonen, LA, Ratsch, G, Schwarz, RF, Butte, AJ, Brazma, A, Chanock, SJ, Chatterjee, N, Stegle, O, Harismendy, O, Bova, GS, Gordenin, DA, Haan, D, Sieverling, L, Feuerbach, L, Chalmers, D, Joly, Y, Knoppers, B, Molnar-Gabor, F, Phillips, M, Thorogood, A, Townend, D, Goldman, M, Fonseca, NA, Xiang, Q, Craft, B, Pineiro-Yanez, E, Munoz, A, Petryszak, R, Fullgrabe, A, Al-Shahrour, F, Keays, M, Haussler, D, Weinstein, J, Huber, W, Valencia, A, Papatheodorou, I, Zhu, J, Fan, Y, Torrents, D, Bieg, M, Chen, K, Chong, Z, Cibulskis, K, Eils, R, Fulton, RS, Gelpi, JL, Gonzalez, S, Gut, IG, Hach, F, Heinold, M, Hu, T, Huang, V, Hutter, B, Jaeger, N, Jung, J, Kumar, Y, Lalansingh, C, Leshchiner, I, Livitz, D, Ma, EZ, Maruvka, YE, Milovanovic, A, Nielsen, MM, Paramasivam, N, Pedersen, JS, Puiggros, M, Sahinalp, SC, Sarrafi, I, Stewart, C, Stobbe, MD, Wala, JA, Wang, J, Wendl, M, Werner, J, Wu, Z, Xue, H, Yamaguchi, TN, Yellapantula, V, Davis-Dusenbery, BN, Grossman, RL, Kim, Y, Heinold, MC, Hinton, J, Jones, DR, Menzies, A, Stebbings, L, Hess, JM, Rosenberg, M, Dunford, AJ, Gupta, M, Imielinski, M, Meyerson, M, Beroukhim, R, Reimand, J, Dhingra, P, Favero, F, Dentro, S, Wintersinger, J, Rudneva, V, Park, JW, Hong, EP, Heo, SG, Kahles, A, jong-Van Lehmann, Soulette, CM, Shiraishi, Y, Liu, F, He, Y, Demircioglu, D, Davidson, NR, 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المصدر: Nature. 578(7793):82

مصطلحات موضوعية: Medicin och hälsovetenskap

الوصول الحر: http://kipublications.ki.se/Default.aspx?queryparsed=id:143672104Test

المؤلفون: Craft, B. R.

مصطلحات موضوعية: 005.74

الوصف: The aim of this research is to describe a useful approach for supporting creativity and problem-solving in the design of Information Visualization software. This type of software is useful for helping people to understand large or complex collections of data by making the data easier to see and use. Because it can be so helpful, many people are motivated to create visualization software to address their own unique problems of understanding data. However, the techniques which visualizations use to enhance cognition of data are not widely known. Also, there are currently few resources which comprehensively describe a method for designing novel visualizations. Consequently, people who seek to build new Information Visualization tools are left to consult design examples, guidelines, and reference models, which do not adequately describe the visualization design process. The key question of the research concerns how Information Visualization methodologies should account for representation of the user, existing visualization design knowledge, and sketching. Given that the current methods of Information Visualization design are incomplete and show evidence of significant shortcomings, how can novice visualization design teams bridge these gaps by using methods from other design disciplines to successfully create effective visualizations To investigate this question, several studies were conducted. Also, a design methodology called So Viz was developed. It incorporates a participatory design approach, using sketching and visualization design patterns to support creativity and problem-solving. A prototype was designed using the SoViz approach. The key contributions of this thesis are results which show that Information Visualization designers can benefit from using this method. The thesis presents the results of using SoViz to create an Information Visualization prototype and describes the theoretical consequences for Information Visualization methodology.

الإتاحة: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686673Test

المؤلفون: Jines, P., Craft, B.

المصدر: eConf C011127 (2001) WEAP037

مصطلحات موضوعية: Physics - Accelerator Physics

الوصف: Louisiana State University Center for Advanced Microstructures and Devices (CAMD) began a control system upgrade project in early 1997. At the time, the storage ring was controlled by a VAX/VMS system, primarily using CAMAC for I/O. The injector Linac was controlled by a separate VME/OS/9 system using custom I/O components. The storage ring control system has been replaced with a PC/Linux based system, utilizing the existing CAMAC subsystem [1]. In an effort to both migrate channels away from CAMAC, and integrate the Linac controls with the storage ring controls, a design for upgrades utilizing AutomationDirect.com PLCs was presented [2]. This paper will discuss the detailed design for the Linac PLC based control system, and discuss the status of PLC upgrades for the Vacuum system, Kicker controls, 2nd RF system, and utilities monitoring.
Comment: Poster Session paper for ICALEPCS 2001 conference, San Jose, California, November 2001 (PSN# WEAP037). 3 pages. PDF format

الوصول الحر: http://arxiv.org/abs/physics/0111113Test

المؤلفون: Zhang, Y., Chen, F., Fonseca, N.A., He, Y., Fujita, M., Nakagawa, H., Zhang, Z., Brazma, A., Amin, S.B., Awadalla, P., Bailey, P.J., Brooks, A.N., Calabrese, C., Chateigner, A., Cortés-Ciriano, I., Craft, B., Craft, D., Creighton, C.J., Davidson, N.R., Demircioglu, D., Erkek, S., Frenkel-Morgenstern, M., Goldman, M.J., Greger, L., Göke, J., Hoadley, K.A., Hou, Y., Huska, M.R., Kahles, A., Khurana, E., Kilpinen, H., Korbel, J.O., Lamaze, F.C., Lehmann, K.-V., Li, C., Li, S., Li, X., Liu, D., Liu, F., Liu, X., Marin, M.G., Markowski, J., Meyerson, M., Nandi, T., Nielsen, M.M., Ojesina, A.I., Ouellette, B.F.F., Pan-Hammarström, Q., Park, P.J., Pedamallu, C.S., Pedersen, J.S., Perry, M.D., Rätsch, G., Schwarz, R.F., Shiraishi, Y., Siebert, R., Soulette, C.M., Stark, S.G., Stegle, O., Su, H., Tan, P., Teh, B.T., Urban, L., Wang, J., Waszak, S.M., Wu, K., Xiang, Q., Xiong, H., Yakneen, S., Yang, H., Ye, C., Yung, C.K., Zhang, F., Zhang, J., Zhang, X., Zheng, L., Zhu, J., Zhu, S., Akdemir, K.C., Alvarez, E.G., Baez-Ortega, A., Beroukhim, R., Boutros, P.C., Bowtell, D.D.L., Brors, B., Burns, K.H., Campbell, P.J., Chan, K., Chen, K., Dueso-Barroso, A., Dunford, A.J., Edwards, P.A., Estivill, X., Etemadmoghadam, D., Feuerbach, L., Fink, J.L., Garsed, D.W., Gerstein, M., Gordenin, D.A., Haan, D., Haber, J.E., Hess, J.M., Hutter, B., Imielinski, M., Jones, D.T.W., Ju, Y.S., Kazanov, M.D., Klimczak, L.J., Koh, Y., Kumar, K., Lee, E.A., Lee, J.J.-K., Li, Y., Lynch, A.G., Macintyre, G., Markowetz, F., Martincorena, I., Martinez-Fundichely, A., Miyano, S., Navarro, F.C.P., Ossowski, S., Pearson, J.V., Puiggròs, M., Rippe, K., Roberts, N.D., Roberts, S.A., Rodriguez-Martin, B., Schumacher, S.E., Scully, R., Shackleton, M., Sidiropoulos, N., Sieverling, L., Stewart, C., Torrents, D., Tubio, J.M.C., Villasante, I., Waddell, N., Wala, J.A., Weischenfeldt, J., Yang, L., Yao, X., Yoon, S.-S., Zamora, J., Zhang, C.-Z., PCAWG Transcriptome Working Group., PCAWG Structural Variation Working Group., PCAWG Consortium.

المساهمون: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL), DUKE-NUS MEDICAL SCHOOL

المصدر: Scopus OA2020

الوصف: 10.1038/s41467-019-13885-w ; Nature Communications ; 11 ; 1 ; 736

العلاقة: Zhang, Y., Chen, F., Fonseca, N.A., He, Y., Fujita, M., Nakagawa, H., Zhang, Z., Brazma, A., Amin, S.B., Awadalla, P., Bailey, P.J., Brooks, A.N., Calabrese, C., Chateigner, A., Cortés-Ciriano, I., Craft, B., Craft, D., Creighton, C.J., Davidson, N.R., Demircioglu, D., Erkek, S., Frenkel-Morgenstern, M., Goldman, M.J., Greger, L., Göke, J., He, Y., Hoadley, K.A., Hou, Y., Huska, M.R., Kahles, A., Khurana, E., Kilpinen, H., Korbel, J.O., Lamaze, F.C., Lehmann, K.-V., Li, C., Li, S., Li, X., Li, X., Liu, D., Liu, F., Liu, X., Marin, M.G., Markowski, J., Meyerson, M., Nandi, T., Nielsen, M.M., Ojesina, A.I., Ouellette, B.F.F., Pan-Hammarström, Q., Park, P.J., Pedamallu, C.S., Pedersen, J.S., Perry, M.D., Rätsch, G., Schwarz, R.F., Shiraishi, Y., Siebert, R., Soulette, C.M., Stark, S.G., Stegle, O., Su, H., Tan, P., Teh, B.T., Urban, L., Wang, J., Waszak, S.M., Wu, K., Xiang, Q., Xiong, H., Yakneen, S., Yang, H., Ye, C., Yung, C.K., Zhang, F., Zhang, J., Zhang, X., Zheng, L., Zhu, J., Zhu, S., Akdemir, K.C., Alvarez, E.G., Baez-Ortega, A., Beroukhim, R., Boutros, P.C., Bowtell, D.D.L., Brors, B., Burns, K.H., Campbell, P.J., Chan, K., Chen, K., Dueso-Barroso, A., Dunford, A.J., Edwards, P.A., Estivill, X., Etemadmoghadam, D., Feuerbach, L., Fink, J.L., Garsed, D.W., Gerstein, M., Gordenin, D.A., Haan, D., Haber, J.E., Hess, J.M., Hutter, B., Imielinski, M., Jones, D.T.W., Ju, Y.S., Kazanov, M.D., Klimczak, L.J., Koh, Y., Kumar, K., Lee, E.A., Lee, J.J.-K., Li, Y., Lynch, A.G., Macintyre, G., Markowetz, F., Martincorena, I., Martinez-Fundichely, A., Miyano, S., Navarro, F.C.P., Ossowski, S., Pearson, J.V., Puiggròs, M., Rippe, K., Roberts, N.D., Roberts, S.A., Rodriguez-Martin, B., Schumacher, S.E., Scully, R., Shackleton, M., Sidiropoulos, N., Sieverling, L., Stewart, C., Torrents, D., Tubio, J.M.C., Villasante, I., Waddell, N., Wala, J.A., Weischenfeldt, J., Yang, L., Yao, X., Yoon, S.-S., Zamora, J., Zhang, C.-Z., PCAWG Transcriptome Working Group., PCAWG Structural Variation Working Group., PCAWG Consortium. (2020). High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations. Nature Communications 11 (1) : 736. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-019-13885-wTest; https://scholarbank.nus.edu.sg/handle/10635/198087Test

الإتاحة: https://doi.org/10.1038/s41467-019-13885-wTest
https://scholarbank.nus.edu.sg/handle/10635/198087Test

المؤلفون: Cortés-Ciriano, I., Lee, J. J-K., Xi, R., Jain, D., Jung, Y. L., Yang, L., Gordenin, D., Klimczak, L. J., Zhang, C-Z., Pellman, D. S., Akdemir, K. C., Alvarez, E. G., Baez-Ortega, A., Beroukhim, R., Boutros, P. C., Bowtell, D. D. L., Brors, B., Burns, K. H., Campbell, P. J., Chan, K., Chen, K., Dueso-Barroso, A., Dunford, A. J., Edwards, P. A., Estivill, X., Etemadmoghadam, D., Feuerbach, L., Fink, J. L., Frenkel-Morgenstern, M., Garsed, D. W., Gerstein, M., Gordenin, D. A., Haan, D., Haber, J. E., Hess, J. M., Hutter, B., Imielinski, M., Jones, D. T. W., Ju, Y. S., Kazanov, M. D., Koh, Y., Korbel, J. O., Kumar, K., Lee, E. A., Li, Y., Lynch, A. G., Macintyre, G., Markowetz, F., Martincorena, I., Martinez-Fundichely, A., Miyano, S., Nakagawa, H., Navarro, F. C. P., Ossowski, S., Park, P. J., Pearson, J. V., Puiggròs, M., Rippe, K., Roberts, N. D., Roberts, S. A., Rodriguez-Martin, B., Schumacher, S. E., Scully, R., Shackleton, M., Sidiropoulos, N., Sieverling, L., Stewart, C., Torrents, D., Tubio, J. M. C., Villasante, I., Waddell, N., Wala, J. A., Weischenfeldt, J., Yao, X., Yoon, S-S., Zamora, J., Aaltonen, L. A., Abascal, F., Abeshouse, A., Aburatani, H., Adams, D. J., Agrawal, N., Ahn, K. S., Ahn, S-M., Aikata, H., Akbani, R., Al-Ahmadie, H., Al-Sedairy, S. T., Al-Shahrour, F., Alawi, M., Albert, M., Aldape, K., Alexandrov, L. B., Ally, A., Alsop, K., Amary, F., Amin, S. B., Aminou, B., Ammerpohl, O., Anderson, M. J., Ang, Y., Antonello, D., Anur, P., Aparicio, S., Appelbaum, E. L., Arai, Y., Aretz, A., Arihiro, K., Ariizumi, S-I., Armenia, J., Arnould, L., Asa, S., Assenov, Y., Atwal, G., Aukema, S., Auman, J. T., Aure, M. R. R., Awadalla, P., Aymerich, M., Bader, G. D., Bailey, M. H., Bailey, P. J., Balasundaram, M., Balu, S., Bandopadhayay, P., Banks, R. E., Barbi, S., Barbour, A. P., Barenboim, J., Barnholtz-Sloan, J., Barr, H., Barrera, E., Bartlett, J., Bartolome, J., Bassi, C., Bathe, O. F., Baumhoer, D., Bavi, P., Baylin, S. B., Bazant, W., Beardsmore, D., Beck, T. A., Behjati, S., Behren, A., Niu, B., Bell, C., Beltran, S., Benz, C., Berchuck, A., Bergmann, A. K., Bergstrom, E. N., Berman, B. P., Berney, D. M., Bernhart, S. H., Berrios, M., Bersani, S., Bertl, J., Betancourt, M., Bhandari, V., Bhosle, S. G., Biankin, A. V., Bieg, M., Bigner, D., Binder, H., Birney, E., Birrer, M., Biswas, N. K., Bjerkehagen, B., Bodenheimer, T., Boice, L., Bonizzato, G., De Bono, J. S., Boot, A., Bootwalla, M. S., Borg, A., Borkhardt, A., Boroevich, K. A., Borozan, I., Borst, C., Bosenberg, M., Bosio, M., Boultwood, J., Bourque, G., Bova, G. S., Bowen, D. T., Bowlby, R., Boyault, S., Boyce, R., Boyd, J., Brazma, A., Brennan, P., Brewer, D. S., Brinkman, A. B., Bristow, R. G., Broaddus, R. R., Brock, J. E., Brock, M., Broeks, A., Brooks, A. N., Brooks, D., Brunak, S., Bruxner, T. J. C., Bruzos, A. L., Buchanan, A., Buchhalter, I., Buchholz, C., Bullman, S., Burke, H., Burkhardt, B., Busanovich, J., Bustamante, C. D., Butler, A. P., Butte, A. J., Byrne, N. J., Børresen-Dale, A-L., Caesar-Johnson, S. J., Cafferkey, A., Cahill, D., Calabrese, C., Caldas, C., Calvo, F., Camacho, N., Campo, E., Cantù, C., Cao, S., Carey, T. E., Carlevaro-Fita, J., Carlsen, R., Cataldo, I., Cazzola, M., Cebon, J., Cerfolio, R., Chadwick, D. E., Chakravarty, D., Chalmers, D., Chan, C. W. Y., Chan-Seng-Yue, M., Chandan, V. S., Chang, D. K., Chanock, S. J., Chantrill, L. A., Chateigner, A., Chatterjee, N., Chayama, K., Chen, H-W., Chen, J., Chen, Y., Chen, Z., Cherniack, A. D., Chien, J., Chiew, Y-E., Chin, S-F., Cho, J., Cho, S., Choi, J. K., Choi, W., Chomienne, C., Chong, Z., Choo, S. P., Chou, A., Christ, A. N., Christie, E. L., Chuah, E., Cibulskis, C., Cibulskis, K., Cingarlini, S., Clapham, P., Claviez, A., Cleary, S., Cloonan, N., Cmero, M., Collins, C. C., Connor, A. A., Cooke, S. L., Cooper, C. S., Cope, L., Corbo, V., Cordes, M. G., Cordner, S. M., Covington, K., Cowin, P. A., Craft, B., Craft, D., Creighton, C. J., Cun, Y., Curley, E., Cutcutache, I., Czajka, K., Czerniak, B., Dagg, R. A., Danilova, L., Davi, M. V., Davidson, N. R., Davies, H., Davis, I. J., Davis-Dusenbery, B. N., Dawson, K. J., De La Vega, F. M., De Paoli-Iseppi, R., Defreitas, T., Tos, A. P. D., Delaneau, O., Demchok, J. A., Demeulemeester, J., Demidov, G. M., Demircioğlu, D., Dennis, N. M., Denroche, R. E., Dentro, S. C., Desai, N., Deshpande, V., Deshwar, A. G., Desmedt, C., Deu-Pons, J., Dhalla, N., Dhani, N. C., Dhingra, P., Dhir, R., DiBiase, A., Diamanti, K., Ding, L., Ding, S., Dinh, H. Q., Dirix, L., Doddapaneni, H., Donmez, N., Dow, M. T., Drapkin, R., Drechsel, O., Drews, R. M., Serge, S., Dudderidge, T., Dunn, M., Dursi, L. J., Duthie, F. R., Dutton-Regester, K., Eagles, J., Easton, D. F., Edmonds, S., Edwards, S. E., Eeles, R. A., Ehinger, A., Eils, J., Eils, R., El-Naggar, A., Eldridge, M., Ellrott, K., Erkek, S., Escaramis, G., Espiritu, S. M. G., Eyfjord, J. E., Faltas, B. M., Fan, D., Fan, Y., Faquin, W. C., Farcas, C., Fassan, M., Fatima, A., Favero, F., Fayzullaev, N., Felau, I., Fereday, S., Ferguson, M. L., Ferretti, V., Field, M. A., Finocchiaro, G., Fisher, C., Fittall, M. W., Fitzgerald, A., Fitzgerald, R. C., Flanagan, A. M., Fleshner, N. E., Flicek, P., Foekens, J. A., Fong, K. M., Fonseca, N. A., Foster, C. S., Fox, N. S., Fraser, M., Frazer, S., Friedman, W., Frigola, J., Fronick, C. C., Fujimoto, A., Fujita, M., Fukayama, M., Fulton, L. A., Fulton, R. S., Furuta, M., Futreal, P. A., Füllgrabe, A., Gabriel, S. B., Gallinger, S., Gambacorti-Passerini, C., Gao, J., Gao, S., Garraway, L., Garred, Ø., Garrison, E., Gehlenborg, N., Gelpi, J. L. L., George, J., Gerhard, D. S., Gerhauser, C., Gershenwald, J. E., Gerstung, M., Getz, G., Ghori, M., Ghossein, R., Giama, N. H., Gibbs, R. A., Gibson, B., Gill, A. J., Gill, P., Giri, D. D., Glodzik, D., Gnanapragasam, V. J., Goebler, M. E., Goldman, M. J., Gomez, C., Gonzalez, S., Gonzalez-Perez, A., Gossage, J., Gotoh, K., Govindan, R., Grabau, D., Graham, J. S., Grant, R. C., Green, A. R., Green, E., Greger, L., Grehan, N., Grimaldi, S., Grimmond, S. M., Grossman, R. L., Grundhoff, A., Gundem, G., Guo, Q., Gupta, M., Gupta, S., Gut, I. G., Gut, M., Göke, J., Ha, G., Haake, A., Haas, S., Haase, K., Habermann, N., Hach, F., Haider, S., Hama, N., Hamdy, F. C., Hamilton, A., Hamilton, M. P., Han, L., Hanna, G. B., Hansmann, M., Haradhvala, N. J., Harismendy, O., Harliwong, I., Harmanci, A. O., Harrington, E., Hasegawa, T., Haussler, D., Hawkins, S., Hayami, S., Hayashi, S., Hayes, D. N., Hayes, S. J., Hayward, N. K., Hazell, S., He, Y., Heath, A. P., Heath, S. C., Hedley, D., Hegde, A. M., Heiman, D. I., Heinold, M. C., Heins, Z., Heisler, L. E., Hellstrom-Lindberg, E., Helmy, M., Heo, S. G., Hepperla, A. J., Heredia-Genestar, J. M., Herrmann, C., Hersey, P., Hilmarsdottir, H., Hinton, J., Hirano, S., Hiraoka, N., Hoadley, K. A., Hobolth, A., Hodzic, E., Hoell, J. I., Hoffmann, S., Hofmann, O., Holbrook, A., Holik, A. Z., Hollingsworth, M. A., Holmes, O., Holt, R. A., Hong, C., Hong, E. P., Hong, J. H., Hooijer, G. K., Hornshøj, H., Hosoda, F., Hou, Y., Hovestadt, V., Howat, W., Hoyle, A. P., Hruban, R. H., Hu, J., Hu, T., Hua, X., Huang, K-L., Huang, M., Huang, M. N., Huang, V., Huang, Y., Huber, W., Hudson, T. J., Hummel, M., Hung, J. A., Huntsman, D., Hupp, T. R., Huse, J., Huska, M. R., Hutter, C. M., Hübschmann, D., Iacobuzio-Donahue, C. A., Imbusch, C. D., Imoto, S., Isaacs, W. B., Isaev, K., Ishikawa, S., Iskar, M., Islam, S. M. A., Ittmann, M., Ivkovic, S., Izarzugaza, J. M. G., Jacquemier, J., Jakrot, V., Jamieson, N. B., Jang, G. H., Jang, S. J., Jayaseelan, J. C., Jayasinghe, R., Jefferys, S. R., Jegalian, K., Jennings, J. L., Jeon, S-H., Jerman, L., Ji, Y., Jiao, W., Johansson, P. A., Johns, A. L., Johns, J., Johnson, R., Johnson, T. A., Jolly, C., Joly, Y., Jonasson, J. G., Jones, C. D., Jones, D. R., Jones, N., Jones, S. J. M., Jonkers, J., Juhl, H., Jung, J., Juul, M., Juul, R. I., Juul, S., Jäger, N., Kabbe, R., Kahles, A., Kahraman, A., Kaiser, V. B., Kakavand, H., Kalimuthu, S., von Kalle, C., Kang, K. J., Karaszi, K., Karlan, B., Karlić, R., Karsch, D., Kasaian, K., Kassahn, K. S., Katai, H., Kato, M., Katoh, H., Kawakami, Y., Kay, J. D., Kazakoff, S. H., Keays, M., Kebebew, E., Kefford, R. F., Kellis, M., Kench, J. G., Kennedy, C. J., Kerssemakers, J. N. A., Khoo, D., Khoo, V., Khuntikeo, N., Khurana, E., Kilpinen, H., Kim, H. K., Kim, H-L., Kim, H-Y., Kim, H., Kim, J., Kim, J. K., Kim, Y., King, T. A., Klapper, W., Kleinheinz, K., Knappskog, S., Kneba, M., Knoppers, B. M., Jan Komorowski, Komura, D., Komura, M., Kong, G., Kool, M., Korchina, V., Korshunov, A., Koscher, M., Koster, R., Kote-Jarai, Z., Koures, A., Kovacevic, M., Kremeyer, B., Kretzmer, H., Kreuz, M., Krishnamurthy, S., Kube, D., Kumar, P., Kumar, S., Kumar, Y., Kundra, R., Kübler, K., Küppers, R., Lagergren, J., Lai, P. H., Laird, P. W., Lakhani, S. R., Lalansingh, C. M., Lalonde, E., Lamaze, F. C., Lambert, A., Lander, E., Landgraf, P., Landoni, L., Langerød, A., Lanzós, A., Larsimont, D., Larsson, E., Lathrop, M., Lau, L. M. S., Lawerenz, C., Lawlor, R. T., Lawrence, M. S., Lazar, A. J., Lazic, A. M., Le, X., Lee, D., Lee, H. J., Lee, J-Y., Lee, J., Lee, M. T. M., Lee-Six, H., Lehmann, K-V., Lehrach, H., Lenze, D., Leonard, C. R., Leongamornlert, D. A., Leshchiner, I., Letourneau, L., Letunic, I., Levine, D. A., Lewis, L., Ley, T., Li, C., Li, C. H., Li, H. I., Li, J., Li, L., Li, S., Li, X., Liang, H., Liang, S-B., Lichter, P., Lin, P., Lin, Z., Linehan, W. M., Lingjærde, O. C., Liu, D., Liu, E. M., Liu, F-F. F., Liu, F., Liu, J., Liu, X., Livingstone, J., Livitz, D., Livni, N., Lochovsky, L., Loeffler, M., Long, G. V., Lopez-Guillermo, A., Lou, S., Louis, D. N., Lovat, L. B., Lu, Y., Lu, Y-J., Luchini, C., Lungu, I., Luo, X., Luxton, H. J., Lype, L., López, C., López-Otín, C., Ma, E. Z., Ma, Y., MacGrogan, G., MacRae, S., Madsen, T., Maejima, K., Mafficini, A., Maglinte, D. T., Maitra, A., Majumder, P. P., Malcovati, L., Malikic, S., Malleo, G., Mann, G. J., Mantovani-Löffler, L., Marchal, K., Marchegiani, G., Mardis, E. R., Margolin, A. A., Marin, M. G., Markowski, J., Marks, J., Marques-Bonet, T., Marra, M. A., Marsden, L., Martens, J. W. M., Martin, S., Martin-Subero, J. I., Maruvka, Y. E., Mashl, R. J., Massie, C. E., Matthew, T. J., Matthews, L., Mayer, E., Mayes, S., Mayo, M., Mbabaali, F., McCune, K., McDermott, U., McGillivray, P. D., McLellan, M. D., McPherson, J. D., McPherson, J. R., McPherson, T. A., Meier, S. R., Meng, A., Meng, S., Menzies, A., Merrett, N. D., Merson, S., Meyerson, M., Meyerson, W., Mieczkowski, P. A., Mihaiescu, G. L., Mijalkovic, S., Mikkelsen, T., Milella, M., Mileshkin, L., Miller, C. A., Miller, D. K., Miller, J. K., Mills, G. B., Milovanovic, A., Minner, S., Miotto, M., Arnau, G. M., Mirabello, L., Mitchell, C., Mitchell, T. J., Miyoshi, N., Mizuno, S., Molnár-Gábor, F., Moore, M. J., Moore, R. A., Morganella, S., Morris, Q. D., Morrison, C., Mose, L. E., Moser, C. D., Muiños, F., Mularoni, L., Mungall, A. J., Mungall, K., Musgrove, E. A., Mustonen, V., Mutch, D., Muyas, F., Muzny, D. M., Muñoz, A., Myers, J., Myklebost, O., Möller, P., Nagae, G., Nagrial, A. M., Nahal-Bose, H. K., Nakagama, H., Nakamura, H., Nakamura, T., Nakano, K., Nandi, T., Nangalia, J., Nastic, M., Navarro, A., Neal, D. E., Nettekoven, G., Newell, F., Newhouse, S. J., Newton, Y., Ng, A. W. T., Ng, A., Nicholson, J., Nicol, D., Nie, Y., Nielsen, G. P., Nielsen, M. M., Nik-Zainal, S., Noble, M. 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مصطلحات موضوعية: RC0254 Neoplasms. Tumors. Oncology (including Cancer)

الوصف: Chromothripsis is a mutational phenomenon characterized by massive, clustered genomic rearrangements that occurs in cancer and other diseases. Recent studies in selected cancer types have suggested that chromothripsis may be more common than initially inferred from low-resolution copy-number data. Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA), we analyze patterns of chromothripsis across 2,658 tumors from 38 cancer types using whole-genome sequencing data. We find that chromothripsis events are pervasive across cancers, with a frequency of more than 50% in several cancer types. Whereas canonical chromothripsis profiles display oscillations between two copy-number states, a considerable fraction of events involve multiple chromosomes and additional structural alterations. In addition to non-homologous end joining, we detect signatures of replication-associated processes and templated insertions. Chromothripsis contributes to oncogene amplification and to inactivation of genes such as mismatch-repair-related genes. These findings show that chromothripsis is a major process that drives genome evolution in human cancer.

وصف الملف: text

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D., McLellan, M. D., McPherson, J. D., McPherson, J. R., McPherson, T. A., Meier, S. R., Meng, A., Meng, S., Menzies, A., Merrett, N. D., Merson, S., Meyerson, M., Meyerson, W., Mieczkowski, P. A., Mihaiescu, G. L., Mijalkovic, S., Mikkelsen, T., Milella, M., Mileshkin, L., Miller, C. A., Miller, D. K., Miller, J. K., Mills, G. B., Milovanovic, A., Minner, S., Miotto, M., Arnau, G. M., Mirabello, L., Mitchell, C., Mitchell, T. J., Miyano, S., Miyoshi, N., Mizuno, S., Molnár-Gábor, F., Moore, M. J., Moore, R. A., Morganella, S., Morris, Q. D., Morrison, C., Mose, L. E., Moser, C. D., Muiños, F., Mularoni, L., Mungall, A. J., Mungall, K., Musgrove, E. A., Mustonen, V., Mutch, D., Muyas, F., Muzny, D. M., Muñoz, A., Myers, J., Myklebost, O., Möller, P., Nagae, G., Nagrial, A. M., Nahal-Bose, H. K., Nakagama, H., Nakagawa, H., Nakamura, H., Nakamura, T., Nakano, K., Nandi, T., Nangalia, J., Nastic, M., Navarro, A., Navarro, F. C. P., Neal, D. E., Nettekoven, G., Newell, F., Newhouse, S. 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A., Rohde, M., Rokutan, H., Romieu, G., Rooman, I., Roques, T., Rosebrock, D., Rosenberg, M., Rosenstiel, P. C., Rosenwald, A., Rowe, E. W., Royo, R., Rozen, S. G., Rubanova, Y., Rubin, M. A., Rubio-Perez, C., Rudneva, V. A., Rusev, B. C., Ruzzenente, A., Rätsch, G., Sabarinathan, R., Sabelnykova, V. Y., Sadeghi, S., Sahinalp, S. C., Saini, N., Saito-Adachi, M., Saksena, G., Salcedo, A., Salgado, R., Salichos, L., Sallari, R., Saller, C., Salvia, R., Sam, M., Samra, J. S., Sanchez-Vega, F., Sander, C., Sanders, G., Sarin, R., Sarrafi, I., Sasaki-Oku, A., Sauer, T., Sauter, G., Saw, R. P. M., Scardoni, M., Scarlett, C. J., Scarpa, A., Scelo, G., Schadendorf, D., Schein, J. E., Schilhabel, M. B., Schlesner, M., Schlomm, T., Schmidt, H. K., Schramm, S-J., Schreiber, S., Schultz, N., Schumacher, S. E., Schwarz, R. F., Scolyer, R. A., Scott, D., Scully, R., Seethala, R., Segre, A. V., Selander, I., Semple, C. A., Senbabaoglu, Y., Sengupta, S., Sereni, E., Serra, S., Sgroi, D. C., Shackleton, M., Shah, N. C., Shahabi, S., Shang, C. A., Shang, P., Shapira, O., Shelton, T., Shen, C., Shen, H., Shepherd, R., Shi, R., Shi, Y., Shiah, Y-J., Shibata, T., Shih, J., Shimizu, E., Shimizu, K., Shin, S. J., Shiraishi, Y., Shmaya, T., Shmulevich, I., Shorser, S. I., Short, C., Shrestha, R., Shringarpure, S. S., Shriver, C., Shuai, S., Sidiropoulos, N., Siebert, R., Sieuwerts, A. M., Sieverling, L., Signoretti, S., Sikora, K. O., Simbolo, M., Simon, R., Simons, J. V., Simpson, J. T., Simpson, P. T., Singer, S., Sinnott-Armstrong, N., Sipahimalani, P., Skelly, T. J., Smid, M., Smith, J., Smith-McCune, K., Socci, N. D., Sofia, H. J., Soloway, M. G., Song, L., Sood, A. K., Sothi, S., Sotiriou, C., Soulette, C. M., Span, P. N., Spellman, P. T., Sperandio, N., Spillane, A. J., Spiro, O., Spring, J., Staaf, J., Stadler, P. F., Staib, P., Stark, S. G., Stebbings, L., Stefánsson, Ó. A., Stegle, O., Stein, L. D., Stenhouse, A., Stewart, C., Stilgenbauer, S., Stobbe, M. D., Stratton, M. R., Stretch, J. R., Struck, A. J., Stuart, J. M., Stunnenberg, H. G., Su, H., Su, X., Sun, R. X., Sungalee, S., Susak, H., Suzuki, A., Sweep, F., Szczepanowski, M., Sültmann, H., Yugawa, T., Tam, A., Tamborero, D., Tan, B. K. T., Tan, D., Tan, P., Tanaka, H., Taniguchi, H., Tanskanen, T. J., Tarabichi, M., Tarnuzzer, R., Tarpey, P., Taschuk, M. L., Tatsuno, K., Tavaré, S., Taylor, D. F., Taylor-Weiner, A., Teague, J. W., Teh, B. T., Tembe, V., Temes, J., Thai, K., Thayer, S. P., Thiessen, N., Thomas, G., Thomas, S., Thompson, A., Thompson, A. M., Thompson, J. F. F., Thompson, R. H., Thorne, H., Thorne, L. B., Thorogood, A., Tiao, G., Tijanic, N., Timms, L. E., Tirabosco, R., Tojo, M., Tommasi, S., Toon, C. W., Toprak, U. H., Torrents, D., Tortora, G., Tost, J., Totoki, Y., Townend, D. https://openaccess.city.ac.uk/view/creators_id/david=2Etownend.htmlTest , Traficante, N., Treilleux, I., Trotta, J-R., Trümper, L. H. P., Tsao, M., Tsunoda, T., Tubio, J. M. C., Tucker, O., Turkington, R., Turner, D. J., Tutt, A., Ueno, M., Ueno, N. T., Umbricht, C., Umer, H. M., Underwood, T. J., Urban, L., Urushidate, T., Ushiku, T., Uusküla-Reimand, L., Valencia, A., Van Den Berg, D. J., Van Laere, S., Van Loo, P., Van Meir, E. G., Van den Eynden, G. G., Van der Kwast, T., Vasudev, N., Vazquez, M., Vedururu, R., Veluvolu, U., Vembu, S., Verbeke, L. P. C., Vermeulen, P., Verrill, C., Viari, A., Vicente, D., Vicentini, C., VijayRaghavan, K., Viksna, J., Vilain, R. E., Villasante, I., Vincent-Salomon, A., Visakorpi, T., Voet, D., Vyas, P., Vázquez-García, I., Waddell, N. M., Waddell, N., Wadelius, C., Wadi, L., Wagener, R., Wala, J. A., Wang, J., Wang, J., Wang, L., Wang, Q., Wang, W., Wang, Y., Wang, Z., Waring, P. M., Warnatz, H-J., Warrell, J., Warren, A. Y., Waszak, S. M., Wedge, D. C., Weichenhan, D., Weinberger, P., Weinstein, J. N., Weischenfeldt, J., Weisenberger, D. J., Welch, I., Wendl, M. C., Werner, J., Whalley, J. P., Wheeler, D. A., Whitaker, H. C., Wigle, D., Wilkerson, M. D., Williams, A., Wilmott, J. S., Wilson, G. W., Wilson, J. M., Wilson, R. K., Winterhoff, B., Wintersinger, J. A., Wiznerowicz, M., Wolf, S., Wong, B. H., Wong, T., Wong, W., Woo, Y., Wood, S., Wouters, B. G., Wright, A. J., Wright, D. W., Wright, M. H., Wu, C-L., Wu, D-Y., Wu, G., Wu, J., Wu, K., Wu, Y., Wu, Z., Xi, L., Xia, T., Xiang, Q., Xiao, X., Xing, R., Xiong, H., Xu, Q., Xu, Y., Xue, H., Yachida, S., Yakneen, S., Yamaguchi, R., Yamaguchi, T. N., Yamamoto, M., Yamamoto, S., Yamaue, H., Yang, F., Yang, H., Yang, J. Y., Yang, L., Yang, L., Yang, S., Yang, T-P., Yang, Y., Yao, X., Yaspo, M-L., Yates, L., Yau, C., Ye, C., Ye, K., Yellapantula, V. D., Yoon, C. J., Yoon, S-S., Yousif, F., Yu, J., Yu, K., Yu, W., Yu, Y., Yuan, K., Yuan, Y., Yuen, D., Yung, C. K., Zaikova, O., Zamora, J., Zapatka, M., Zenklusen, J. C., Zenz, T., Zeps, N., Zhang, C-Z., Zhang, F., Zhang, H., Zhang, H., Zhang, H., Zhang, J., Zhang, J., Zhang, J., Zhang, X., Zhang, X., Zhang, Y., Zhang, Z., Zhao, Z., Zheng, L., Zheng, X., Zhou, W., Zhou, Y., Zhu, B., Zhu, H., Zhu, J., Zhu, S., Zou, L., Zou, X., deFazio, A., van As, N., van Deurzen, C. H. M., van de Vijver, M. J., van’t Veer, L. von Mering, C.view all authorsEPJS_limit_names_shown_load( 'creators_name_32290_et_al', 'creators_name_32290_rest' ); (2020). Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing. Nature Genetics, 52(3), pp. 331-341. doi:10.1038/s41588-019-0576-7 https://doi.org/10.1038/s41588-019-0576-7Test

الإتاحة: https://doi.org/10.1038/s41588-019-0576-7Test
https://openaccess.city.ac.uk/id/eprint/32290Test/
https://openaccess.city.ac.uk/id/eprint/32290/1/s41588-019-0576-7.pdfTest
https://openaccess.city.ac.uk/id/eprint/32290/2/s41588-020-0634-1.pdfTest
https://openaccess.city.ac.uk/id/eprint/32290/3/s41588-023-01315-z.pdfTest

المؤلفون: Craft, B, Fisher, S

المصدر: Climate Policy , 18 (9) pp. 1203-1209. (2018)

الوصف: The Paris Agreement establishes a global goal on adaptation which will be assessed through the global stocktake, the first attempt by the international climate change regime to measure collective progress on adaptation. This policy analysis identifies four main challenges to designing a meaningful assessment. These are: designing a system that can aggregate results; managing the dual mandate of reviewing collective progress and informing the enhancement of national level actions; methodological challenges in adaptation; and political challenges around measurement. We propose a mixed-methods approach to addressing these challenges, combining short-term needs for reporting with longer-term aims of enhancing national adaptation actions.

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10062822/1/CraftFisherAdaptationGoal_acceptedClimatePolicy.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10062822Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10062822/1/CraftFisherAdaptationGoal_acceptedClimatePolicy.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10062822Test/

المؤلفون: Laurillard, D., Charlton, P., Craft, B.

المصدر: Journal of Computer Assisted Learning. Feb 2013 29(1):15-30.

تمت مراجعته من قبل الزملاء: Y

Page Count: 16

الواصفات: Teacher Improvement, Instructional Innovation, Instructional Design, Instructional Improvement, Technological Literacy, Technology Integration, Technology Education, Program Descriptions, Teacher Education Programs, Blended Learning, Instructional Development, Improvement Programs, Change Strategies, Training Methods, Capacity Building, Educational Technology, Teaching Models, Educational Environment, Scaffolding (Teaching Technique)

مستخلص: The use of digital technologies is now widespread and increasing, but is not always optimized for effective learning. Teachers in higher education have little time or support to work on innovation and improvement of their teaching, which often means they simply replicate their current practice in a digital medium. This paper makes the case for a learning design support environment to support and scaffold teachers' engagement with and development of technology-enhanced learning, based on user requirements and on pedagogic theory. To be able to adopt, adapt, and experiment with learning designs, teachers need a theory-informed way of representing the critical characteristics of good pedagogy as they discover how to optimize learning technologies. This paper explains the design approach of the Learning Design Support Environment project, and how it aims to support teachers in achieving this goal. (Contains 5 tables and 2 figures.)

Abstractor: As Provided

المؤلفون: Aguet, F, Brown, AA, Castel, SE, Davis, JR, He, Y, Jo, B, Mohammadi, P, Park, Y, Parsana, P, Segre, AV, Strober, BJ, Zappala, Z, Cummings, BB, Gelfand, ET, Hadley, K, Huang, KH, Lek, M, Li, X, Nedzel, JL, Nguyen, DY, Noble, MS, Sullivan, TJ, Tukiainen, T, MacArthur, DG, Getz, G, Management, NP, Addington, A, Guan, P, Koester, S, Little, AR, Lockhart, NC, Moore, HM, Rao, A, Struewing, JP, Volpi, S, Collection, B, Brigham, LE, Hasz, R, Hunter, M, Johns, C, Johnson, M, Kopen, G, Leinweber, WF, Lonsdale, JT, McDonald, A, Mestichelli, B, Myer, K, Roe, B, Salvatore, M, Shad, S, Thomas, JA, Walters, G, Washington, M, Wheeler, J, Bridge, J, Foster, BA, Gillard, BM, Karasik, E, Kumar, R, Miklos, M, Moser, MT, Jewell, SD, Montroy, RG, Rohrer, DC, Valley, D, Mash, DC, Davis, DA, Sobin, L, Barcus, ME, Branton, PA, Grp, EMW, Abell, NS, Balliu, B, Delaneau, O, Fresard, L, Gamazon, ER, Garrido-Martin, D, Gewirtz, ADH, Gliner, G, Gloudemans, MJ, Han, B, He, AZ, Hormozdiari, F, Liu, B, Kang, EY, McDowell, IC, Ongen, H, Palowitch, JJ, Peterson, CB, Quon, G, Ripke, S, Saha, A, Shabalin, AA, Shimko, TC, Sul, JH, Teran, NA, Tsang, EK, Zhang, H, Zhou, Y-H, Bustamante, CD, Cox, NJ, Guigo, R, Kellis, M, McCarthy, MI, Conrad, DF, Eskin, E, Li, G, Nobel, AB, Sabatti, C, Stranger, BE, Wen, X, Wright, FA, Ardlie, KG, Dermitzakis, ET, Lappalainen, T, Battle, A, Brown, CD, Engelhardt, BE, Montgomery, SB, Handsaker, RE, Kashin, S, Karczewski, KJ, Nguyen, DT, Trowbridge, CA, Barshir, R, Basha, O, Bogu, GK, Brown, A, Chen, LS, Chiang, C, Damani, FN, Ferreira, PG, Hall, IM, Howald, C, Im, HK, Kim, Y, Kim-Hellmuth, S, Mangul, S, Monlong, J, Munoz-Aguirre, M, Ndungu, AW, Nicolae, DL, Oliva, M, Panousis, N, Papasaikas, P, Payne, AJ, Quan, J, Reverter, F, Sammeth, M, Scott, AJ, Sodaei, R, Stephens, M, Urbut, S, De Bunt, MV, Wang, G, Xi, HS, Yeger-Lotem, E, Zaugg, JB, Akey, JM, Bates, D, Chan, J, Claussnitzer, M, Demanelis, K, Diegel, M, Doherty, JA, Feinberg, AP, Fernando, MS, Halow, J, Hansen, KD, Haugen, E, Hickey, PF, Hou, L, Jasmine, F, Jian, R, Jiang, L, Johnson, A, Kaul, R, Kibriya, MG, Lee, K, Li, JB, Li, Q, Lin, J, Lin, S, Linder, S, Linke, C, Liu, Y, Maurano, MT, Molinie, B, Nelson, J, Neri, FJ, Pierce, BL, Rinaldi, NJ, Rizzardi, LF, Sandstrom, R, Skol, A, Smith, KS, Snyder, MP, Stamatoyannopoulos, J, Tang, H, Wang, L, Wang, M, Van Wittenberghe, N, Wu, F, Zhang, R, Fund, NC, Nierras, CR, Nci, N, Carithers, LJ, Vaught, JB, Nhgri, N, Gould, SE, Lockart, NC, Martin, C, Nimh, N, Addington, AM, Koester, SE, Nida, N, Valley, DR, Undale, AH, Smith, AM, Tabor, DE, Roche, NV, McLean, JA, Vatanian, N, Robinson, KL, Valentino, KM, Qi, L, Hunter, S, Hariharan, P, Singh, S, Um, KS, Matose, T, Tomaszewski, MM, Study, E, Barker, LK, Mosavel, M, Siminoff, LA, Traino, HM, Flicek, P, Juettemann, T, Ruffier, M, Sheppard, D, Taylor, K, Trevanion, SJ, Zerbino, DR, Craft, B, Goldman, M, Haeussler, M, Kent, WJ, Lee, CM, Paten, B, Rosenbloom, KR, Vivian, J, Zhu, J

الوصف: Characterization of the molecular function of the human genome and its variation across individuals is essential for identifying the cellular mechanisms that underlie human genetic traits and diseases. The Genotype-Tissue Expression (GTEx) project aims to characterize variation in gene expression levels across individuals and diverse tissues of the human body, many of which are not easily accessible. Here we describe genetic effects on gene expression levels across 44 human tissues. We find that local genetic variation affects gene expression levels for the majority of genes, and we further identify inter-chromosomal genetic effects for 93 genes and 112 loci. On the basis of the identified genetic effects, we characterize patterns of tissue specificity, compare local and distal effects, and evaluate the functional properties of the genetic effects. We also demonstrate that multi-tissue, multi-individual data can be used to identify genes and pathways affected by human disease-associated variation, enabling a mechanistic interpretation of gene regulation and the genetic basis of disease.

العلاقة: pii: nature24277; Aguet, F., Brown, A. A., Castel, S. E., Davis, J. R., He, Y., Jo, B., Mohammadi, P., Park, Y., Parsana, P., Segre, A. V., Strober, B. J., Zappala, Z., Cummings, B. B., Gelfand, E. T., Hadley, K., Huang, K. H., Lek, M., Li, X., Nedzel, J. L. ,. Zhu, J. (2017). Genetic effects on gene expression across human tissues. NATURE, 550 (7675), pp.204-+. https://doi.org/10.1038/nature24277Test.; http://hdl.handle.net/11343/307525Test

الإتاحة: https://doi.org/10.1038/nature24277Test
http://hdl.handle.net/11343/307525Test

المؤلفون: Todd, D. J., Craft, B. B., Vaydich, J. L.

المصدر: School of Psychology, Family, and Community Research Conference

الوصف: Misrepresentation in online dating platforms has become more common. Individuals purposefully misrepresent themselves in relationship goals, personal assets, past relationships, personal attributes, personal interests, and attractiveness. External shame, where an individual perceives themselves as existing negatively in the mind of another, has been linked to the use of misrepresentation. There is a gap in the existing literature on how external shame impacts the use of misrepresentation in the context of online dating. Data is being gathered using self-report surveys. Results will be discussed in terms of the impact that external shame has on misrepresentation in the context of online dating.

العلاقة: https://digitalcommons.spu.edu/spfc_research_conference/spfc_conf_2022/spfc_conf_2022_events/19Test

الإتاحة: https://digitalcommons.spu.edu/spfc_research_conference/spfc_conf_2022/spfc_conf_2022_events/19Test

المؤلفون: Avramides, K, Craft, B, Luckin, R

المصدر: Interactive Learning Environments , 24 (1) pp. 33-48. (2016)

مصطلحات موضوعية: context, design, informal learning, energy, teenagers

الوصف: © 2013 Taylor & Francis. Energy sustainability is prevalent in political and popular rhetoric and yet energy consumption is rising. Teenagers are an important category of future energy consumers, but little is known of their conceptions about energy and energy saving. We report on empirical research with two groups of teenagers. This is part of ongoing work to design learning technologies that support teenagers learn about personal energy consumption. In this paper we describe our analysis and methodology, which are shaped by the Ecology of Resources (EoR) design framework [Luckin, R. (2010). Re-designing learning contexts: Technology-rich, learner-centred ecologies. London and New York, NY: Routledge]. Our findings informed the development of an EoR model of the participants' personal context, which includes their world resources (people, tools, knowledge, skills, and environment) and their personal resources (conceptions, motivations and concerns around energy consumption). We discuss the range of methods we employed to understand learners' personal contexts. These findings contribute to our understanding of how to explore teenagers' personal contexts and have implications for the design of technology to support learning about personal energy consumption.

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/1474757/1/Avramides%20et%20al%20%20in%20press.pdfTest; https://discovery.ucl.ac.uk/id/eprint/1474757Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/1474757/1/Avramides%20et%20al%20%20in%20press.pdfTest
https://discovery.ucl.ac.uk/id/eprint/1474757Test/